ACR Meeting Abstracts

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Abstracts tagged "dermatomyositis"

  • Abstract Number: 1142 • ACR Convergence 2024

    Disease Trajectory in anti-MDA5 Dermatomyositis Patients Presented with Different Stage of Interstitial Lung Disease

    TING-YUAN LAN1, Tai-Ju Lee2, Ting-Wei Chang3, Chiao-Feng Cheng4, Chieh-Yu Shen5, Cheng-Hsun Lu6, Kuan-Yen Lin7, Song-Chou Hsieh8 and Ko-Jen Li9, 1National Taiwan University Hospital Hsinchu Branch, Hsinchu City, Taiwan, 2National Taiwan University Hospital Hsinchu Branch, Hsinchu City, Taiwan (Republic of China), 3National Taiwan University Hospital HsinChu Branch, Taichung, Taiwan, 4National Taiwan University Hospital Yun-Lin Branch, Yun-Lin County, Taiwan, 5National Taiwan Universtiy Hospital, Taipei, Taiwan (Republic of China), 6National Taiwan University Hospital, Taipei, Taiwan, 7National Taiwan University Hospital Hsin-Chu branch, Hsinchu, Taiwan (Republic of China), 8National Taiwan Unuversity Hospital, Taipei City, Taiwan, 9National Taiwan University Hospital, Taipei

    Background/Purpose: The necessity of intensive combination immunotherapy for all patients with anti-MDA5 ILD is debated, given the variable progression of the disease, risk of infection…
  • Abstract Number: 1268 • ACR Convergence 2024

    Neutrophil Lymphocyte Ratio as a Novel Marker of Skin Disease Activity in Older Children with Juvenile Dermatomyositis

    Shreya Swaminathan1, Nidhi Naik2, Susan Shenoi3, Sarah Vandenbergen4, Jessica Turnier5, Zilan Zheng6, Jessica Neely6, James Andrews7 and Christian Lood8, 1University of Washington, Seattle, 2Seattle children's hospital, Bothell, WA, 3Seattle Children's Hospital and Research Center, Mercer Island, WA, WA, 4University of Michigan, Ann Arbor, MI, 5University of Michigan, Saline, MI, 6UCSF, San Francisco, CA, 7University of Alabama at Birmingham, Birmingham, AL, 8University of Washington, Seattle, WA

    Background/Purpose: Exaggerated neutrophil activation can lead to inflammation and organ damage in rheumatic diseases, including dermatomyositis (DM). In both juvenile (JDM) and adult DM, markers…
  • Abstract Number: 2064 • ACR Convergence 2024

    Quantifying Cutaneous Dermatomyositis: A Novel 3D Image-based Approach

    Nantakarn Pongtarakulpanit1, Tanya Chandra1, shiri keret2, Eugenia Gkiaouraki3, Vladimir Liarski1, Dana Ascherman3, Siamak Mogahadam1, Chester Oddis1 and Rohit Aggarwal4, 1Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 2Rheumatology unit, Bnai-Zion medical center and the faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Atlit, Israel, 3Division of Rheumatology and Clinical Immunology, University of Pittsburgh Medical Center, Pittsburgh, PA, 4Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA

    Background/Purpose: Rapid advancement in image analysis now has a critical role in the diagnosis and assessment of skin lesions. The current standard of visual examination…
  • Abstract Number: 0334 • ACR Convergence 2024

    Normal Creatine Kinase in Idiopathic Inflammatory Myopathies- Patient Characteristics and Disease Activity

    shiri keret1, Tanya Chandra2, Lisa Kaly3, Raisa Silva4, Eugenia Gkiaouraki5, Nantakarn Pongtarakulpanit6, shreya Sriram5, Rajesh Gopalarathinam7, Siamak Mogahadam6, Chester Oddis6 and Rohit Aggarwal8, 1Rheumatology unit, Bnai-Zion medical center and the faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Atlit, Israel, 2University of Pittsburgh Medical Center, Pittsburgh, PA, 3Rheumatology unit, Bnai-Zion medical center and the faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Haifa, Israel, 4Internal medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, 5Division of Rheumatology and Clinical Immunology, University of Pittsburgh Medical Center, Pittsburgh, PA, 6Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 7Division of Rheumatology, Wrightington Wigan and Leigh Teaching Hospitals NHS Foundation Trust, Wigan, United Kingdom, 8Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA

    Background/Purpose: Creatine kinase (CK) is an important biomarker for the diagnosis and monitoring of Idiopathic Inflammatory Myopathies (IIM). However, in some cases, CK levels might…
  • Abstract Number: 1143 • ACR Convergence 2024

    Epidemiology and Spectrum of Idiopathic Inflammatory Myopathies in Individuals of Sub-Saharan Ancestry: Data from the Tertiary Care Center of the Caribbean Island of Martinique

    Benoit Suzon1, Rachel Robert1, Fabienne Louis-sidney2, Arthur Felix1, Illitch Coco-Viloin1, Florence Moinet3, Rodolphe Cougnaud1, Rémi Bellance1, Emmanuelle Amazan1, Emma pierrisnard1, Moustapha Agossou1, Christophe Deligny4 and Aurore Abel1, 1University Hospital of Martinique, Fort-de-France, Martinique, 2University Hospital Martinique, Fort De France, Martinique, 3University Hospital of Martinique, Fort de France, France, 4University Hospital of Martinique - National reference center for autoimmune disease, Internal Medicine, Fort-de-France, Martinique

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) are heterogeneous systemic autoimmune diseases with a worldwide incidence ranging from 0.116 to 1.9 and a prevalence from 2.4 to…
  • Abstract Number: 1269 • ACR Convergence 2024

    Altered Tryptophan Metabolism in Juvenile Dermatomyositis Is Associated with Muscle Damage and Mental Health

    Yang Wu1, Aviya Lanis2, Jorge Armando Gonzalez-Chapa3, Jia Shi1, qian wang4, Mengtao Li4, Xiaofeng Zeng5, Susan Shenoi6 and Christian Lood3, 1University of Washington, Seattle, 2Seattle Children's Hospital, Seattle, 3University of Washington, Seattle, WA, 4Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China 2National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Ministry of Science & Technology, Beijing, China, 5Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 6Seattle Children's Hospital and Research Center, Mercer Island, WA, WA

    Background/Purpose: Children with juvenile dermatomyositis (JDM) and juvenile idiopathic arthritis (JIA) experience impaired quality of life and high rates of anxiety and depression. The underlying…
  • Abstract Number: 2065 • ACR Convergence 2024

    Proposed Pathways Involved in the Pathogenesis of Juvenile Dermatomyositis (JDM)

    Samantha Coss1, Danlei Zhou1, Rabheh Abdul Aziz2, Katherine Miller3, Shoghik Akoghlanian4, Kyla Driest1, Edward Oberle1, Vidya Sivaraman5, Charles Spencer6, Stacy Ardoin1 and Chack-Yung Yu7, 1Nationwide Children's Hospital, Columbus, OH, 2University at Buffalo, Buffalo, NY, 3Nationwide Children's Hospital, Institute for Genomic Medicine, Columbus, OH, 4Nationwide Children�s Hospital, Columbus, OH, 5Nationwide Children's Hospital/ The Ohio State University, Columbus, OH, 6University of Mississippi Medical Center, Jackson, MS, 7Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, OH

    Background/Purpose: JDM is an autoimmune disease of skin and muscle. We investigated genetic factors, autoantibodies, and clinical features in JDM.Methods: Subjects came from 2 large…
  • Abstract Number: 0335 • ACR Convergence 2024

    Analysis of the Prevalence of Diabetes Mellitus in Patients with Adult-onset Dermatomyositis

    Komal Ejaz1, Chao Zhang2 and Soumya Chatterjee3, 1Cleveland Clinic, Cleveland, OH, 2Cleveland Clinic, Cleveland Heights, OH, 3Cleveland Clinic, Richmond Heights, OH

    Background/Purpose: Dermatomyositis is an idiopathic inflammatory myopathy with proximal muscle weakness and skin manifestations. Myositis patients have poor overall health partially due to co-morbidities. Data…
  • Abstract Number: 1145 • ACR Convergence 2024

    Clinico-Immunological Profile and Treatment Outcomes of Clinically Significant Diaphragmatic Weakness in Patients with Idiopathic Inflammatory Myopathies: Results from the Largest Single-Center Cohort of 16 Cases

    Siddharth Jain1, Bhargavi Pridhivi2, Adil Rashid Khan2, Stanzin Spalkit2, Manish Soneja2, Mehar Chand Sharma2, Sanjeev Sinha2, Uma Kumar2 and Naveet Wig2, 1All India Institute of Medical Sciences, New Delhi, Delhi, Delhi, India, 2All India Institute of Medical Sciences, New Delhi, Delhi, India

    Background/Purpose: Diaphragmatic myositis is rarely reported in patients with idiopathic inflammatory myopathy (IIM) but is associated with high morbidity and mortality. Epidemiology, spectrum of clinical…
  • Abstract Number: 1272 • ACR Convergence 2024

    Angiopoietin-2 and Soluble Tumor Necrosis Factor Receptor Type II Are Elevated in Treatment Naïve JDM Plasma and Associate with Increased Muscle Disease Activity and Decreased Nailfold Capillary Density

    Sophia Matossian1, Julie Sturza2, Megan Mattichak1, William Brodie1, Christine Goudsmit1, Nicholas McClellan1, J. Michelle Kahlenberg1, Pei-Suen Tsou1 and Jessica Turnier3, 1University of Michigan, Ann Arbor, MI, 2Michigan Medicine Biostatistics and Data Management, Ann Arbor, MI, 3University of Michigan, Saline, MI

    Background/Purpose: Juvenile Dermatomyositis (JDM) is an autoimmune disease characterized by vasculopathy in skin and muscle, where endothelial cell (EC) dysfunction is thought to contribute to…
  • Abstract Number: 2066 • ACR Convergence 2024

    Comparative Diagnostic Efficacy of Quantitative Measurement of Echo Intensity and Texture versus Qualitative Analysis of Ultrasound Images in Myositis

    Takeshi Yoshida1, Hiroki Yamazaki2, Naoko Takamatsu2, Yoshinori Taniguchi3, Taiki Nozaki4, masataka inoue5, Yoshitaka Kumon6, yuki matsumoto2, Yuki Kanazawa2, Masafumi Harada2, Ichizo Nishino7, Jemima Albayda8 and Yuishin Izumi2, 1Chikamori Hospital, Kochi, Kochi, Japan, 2Tokushima University School of Medicine, Tokushima, Japan, 3Kochi University School of Medicine, kochi, Japan, 4keio University School of Medicine, Tokyo, Japan, 5Hyogo Medical University, Nishinomiya, Japan, 6Chikamori Hospital, Kochi, Japan, 7National Center of Neurology and Psychiatry, Tokyo, Japan, 8Johns Hopkins School of Medicine, Baltimore, MD

    Background/Purpose: Recently, the role of imaging tests such as magnetic resonance imaging and ultrasound (US) in the diagnosis and classification of myositis has become increasingly…
  • Abstract Number: 0336 • ACR Convergence 2024

    Mortality: Comparison, Causes and Determinants in Subgroups of Idiopathic Inflammatory Myopathies

    Aurore Larrauffie1, Chloé Bost1, Marie Faruch1, Elisabeth Uro-coste1, Grégoire Prevot1, Thomas Villeneuve1, Jérémy Zordan1, Claire Barrier1, Morgane Mourguet2, Marie Guille1, Laurent Sailler1, Laurent Alric1, Sébastien De Almeida Chaves1 and Grégory Pugnet3, 1CHU Toulouse, Toulouse, France, 2service de médecine interne CHU Toulouse RANGUEIL, Toulouse, France, 3Toulouse Rangueil University Hospital, Toulouse, France

    Background/Purpose: Idiopathic Inflammatory Myopathies (IIMs) are a group of heterogeneous connective tissue diseases including dermatomyositis (DM), polymyositis (PM), anti-synthetase syndromes (ASS), immune-mediated necrotizing myopathies (NM),…
  • Abstract Number: 1148 • ACR Convergence 2024

    Simplified Cutaneous Dermatomyositis Disease Area and Severity Index Activity Scores for Cutaneous Dermatomyositis

    Nantakarn Pongtarakulpanit1, Tanya Chandra1, shiri keret2, Eugenia Gkiaouraki3, Vladimir Liarski1, Dana Ascherman3, Siamak Mogahadam1, Chester Oddis1 and Rohit Aggarwal4, 1Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 2Rheumatology unit, Bnai-Zion medical center and the faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Atlit, Israel, 3Division of Rheumatology and Clinical Immunology, University of Pittsburgh Medical Center, Pittsburgh, PA, 4Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA

    Background/Purpose: The Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI) is a clinician-scored instrument that measures activity and damage in the skin of Dermatomyositis (DM)…
  • Abstract Number: 1281 • ACR Convergence 2024

    The Brazilian Registry of Juvenile Dermatomyositis: Relationship Between Ultraviolet Radiation and Laboratory Markers of Juvenile Dermatomyositis in a Tropical Country

    Beatriz Carneiro1, Adriana Elias2, Claudia Saad-Magalhaes3, Erick Kill2, Sylvia Farhat2, Teresa Robazzi4, Ana Julia Moraes5, Sheila Oliveira6, Luciana Carvalho7, Taciana Fernandes3, Carlos Rabello8, Maria Teresa Terreri9, Silvana Sacchetti10, Simone Appenzeller11, Clovis Silva12, Claudio Len13, Darcisio Antonio14, Iloite Scheibel15, Melissa Fraga16, Marcia Bandeira17, Andre Cavalcante18, Ana Paula Vecchi19, Roberto Marini20, Flavio Sztajnbok21, Nadia Aikawa22, lucia Maria Campos2, Katia Kozu2 and Maria Paula Ribeiro2, 1University of São Paulo, São Paulo, SP, Brazil, 2University of Sao Paulo, São Paulo, SP, 3São Paulo State University, Botucatu, 4University of Bahia, Salvador, 5Para Federal University, Belém do Pará, 6Rio de Janeiro Federal University, Rio de Janeiro, Brazil, 7University of São Paulo (Ribeirao Preto), Ribeirao Preto, 8Albert Sabin Children's Hospital, Fortaleza, 9UNIFESP, São Paulo, SP, Brazil, 10Santa Casa Medical School, São Paulo, SP, Brazil, 11Unicamp, Campinas, SP, Brazil, 12Rheumatology Division and Pediatric Rheumatology Unit, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, SP, Brazil, 13Federal University of Sao Paulo, São Paulo, SP, 14São Paulo State University, Botucatu, SP, Brazil, 15Conceição's Hospital of Porto Alegre, Porto Alegre, 16Universidade Federal de São Paulo, São Paulo, SP, Brazil, 17Pequeno Principe Hospital, Curitiba, 18Pernambuco Federal University, Recife, 19Children's Hospital of Goiania, Goiânia, 20Campinas State University, Campinas, 21UFRJ/UERJ, SAO PAULO, Brazil, 22Rheumatology Division and Pediatric Rheumatology Unit, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil

    Background/Purpose: Ultraviolet (UV) waves are risk factors for juvenile dermatomyositis (JDM), when compared to other types of myositis without skin involvement. Patients with JDM have…
  • Abstract Number: 2069 • ACR Convergence 2024

    Cancer Risk and Screening Effectiveness in Idiopathic Inflammatory Myopathy: Validating IMACS Guidelines in a Retrospective Indian Cohort

    Lovely Kumari1, VISHNU KONERU2, subin Philip1, sai Kumar Dunga3, Mamatha gorijavulu4, Aishwarya Gopal5, Christina Mariaselvam6, Molly Thabah7, Vir Singh Negi8 and Chengappa Kavadichanda9, 1JIPMER,PUDUCHERRY, PUDUCHERRY, Puducherry, India, 2JIPMER,PUDUCHERRY, PUDUCHERRY, India, 3JIPMER,PUDUCHERRY, VIZAG, Andhra Pradesh, India, 4JIPMER,PUDUCHERRY, HYDERABAD, Andhra Pradesh, India, 5Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, Puducherry, India, 6JIPMER, Puducherry, Puducherry, India, 7Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, Puducherry, India, 8AIIMS BILASPUR, BILASPUR, Himachal Pradesh, India, 9Jawaharlal Institute of Postgraduate Medical Education and Research, pondicherry, Puducherry, India

    Background/Purpose: Idiopathic inflammatory myopathy (IIM) carries an elevated cancer risk. The International Myositis Assessment and Clinical Studies Group (IMACS) has issued evidence-based guidelines for cancer…
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