Abstracts tagged "Comorbidity"

Abstract Number: 580 • 2019 ACR/ARP Annual Meeting
Association of Comorbidities with Disease Activity and Functional Impairment in Axial Spondyloarthritis: Results from a Nationwide Population-Based Study
Imke Redeker¹, Johanna Callhoff ², Falk Hoffmann ³, Hildrun Haibel ⁴, Joachim Sieper ⁴, Angela Zink ⁵ and Denis Poddubnyy ⁶, ¹Charité – Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, ²German Rheumatism Research Centre, Berlin, Germany, ³Carl von Ossietzky University, Oldenburg, Germany, ⁴Charité Universitätsmedizin Berlin, Germany, Berlin, Germany, ⁵German Rheumatism Research Centre and Charité University medicine, Berlin, Germany, ⁶Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany
Background/Purpose: Data on the prevalence of comorbidities and their association with disease activity and functional impairment in axial spondyloarthritis (axSpA) are scarce. The aim of…
Abstract Number: 841 • 2019 ACR/ARP Annual Meeting
Elevation of Anti-Citrullinated Protein Antibodies Prior to Rheumatoid Arthritis Onset and Risks for Developing Chronic Obstructive Pulmonary Disease or Asthma
Alessandra Zaccardelli¹, Xinyi Liu ¹, Julia Ford ¹, Jing Cui ¹, Bing Lu ¹, Su H. Chu ², Peter Schur ¹, Cameron Speyer ¹, Karen Costenbader ¹, William Robinson ³, Jeremy Sokolove ⁴, Elizabeth Karlson ¹, Carlos Camargo ⁵ and Jeffrey Sparks ¹, ¹Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Stanford University, Stanford, CA, ⁴AbbVie Immunology Clinical Development, Redwood City, ⁵Massachusetts General Hospital, Boston, MA
Background/Purpose: Elevation of anti-citrullinated protein antibodies (ACPA) precedes clinical rheumatoid arthritis (RA) diagnosis by years and may originate at inflamed mucosa, including airways. Damage from…
Abstract Number: 1219 • 2019 ACR/ARP Annual Meeting
Uric Acid Level as a Predictor of Long Term Mortality in Advanced Age Population
‪Gabriel Breuer‬‏¹, Marwan Abu Sneineh‬‏ ¹ and Gideon Nesher ¹, ¹Shaare Zedek Medical Center, Jerusalem, Yerushalayim, Israel
Background/Purpose: Hyperuricemia is associated with the development, progression and outcome of several diseases. The purpose of this study is to evaluate the serum uric acid…
Abstract Number: 1483 • 2019 ACR/ARP Annual Meeting
Effect of Phosphodiesterase 4 Inhibition with Apremilast on Cardiometabolic Outcomes in Psoriatic Arthritis – Initial Results from the Immune Metabolic Associations in Psoriatic Arthritis (IMAPA) Study
Lyn Ferguson¹, Paul Welsh ¹, Rosemary Brown ¹, Alistair Tindell ², Sean Kerrigan ³, Naveed Sattar ¹, Iain McInnes ⁴ and Stefan Siebert ⁴, ¹Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom, ²Institute of Infection Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom, ³Institute of infection, immunity and inflammation, Glasgow, ⁴Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: Psoriatic arthritis (PsA) is associated with obesity and increased cardiometabolic risk. Weight loss has been noted in association with the phosphodiesterase 4 (PDE4) inhibitor…
Abstract Number: 2013 • 2019 ACR/ARP Annual Meeting
Increased Accumulation of Malondialdehyde-Acetaldehyde Modified HDL in Macrophage Without Decreased Cholesterol Efflux
Kevin Real¹, Michael Duryee ¹, Patrick Opperman ¹, Evan Ryan ¹, Logan Duryee ¹, James O'Dell ², Ted Mikuls ², Daniel Anderson ¹ and Geoffrey Thiele ², ¹University of Nebraska Medical Center, Omaha, NE, ²VA Nebraska-Western IA Health Care System & University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Patients with rheumatoid arthritis (RA) are approximately two-fold more likely to develop cardiovascular disease (CVD). Prior reports have suggested that “dysfunctional” HDL may explain…
Abstract Number: 2070 • 2019 ACR/ARP Annual Meeting
Co-morbidities in Patients with OA and RA: Results from a Large US Rheumatic Disease Registry
Sofia Pedro¹, Rebecca Schumacher ¹, Alyssa Dominique ², Yomei Shaw ¹, Kristin Wipfler ¹ and Kaleb Michaud ³, ¹FORWARD, The National Databank for Rheumatic Diseases, Wichita, KS, ²Bristol-Myers Squibb, Princeton, NJ, ³FORWARD, The National Databank for Rheumatic Diseases and University of Nebraska Medical Center, Wichita, KS
Background/Purpose: The burden of co-morbid conditions can impact the overall quality of life in patients with RA and OA. However, the presence of common co-morbidities…
Abstract Number: 2295 • 2019 ACR/ARP Annual Meeting
Burden of Systemic Lupus Erythematosus Among Korean Women in Childbearing Years Based on the National Health Insurance Service Data
Min Kyung Chung ¹, Jin Su Park ², Hyun Sun Lim ², Chan Hee Lee ² and Jisoo Lee¹, ¹Division of Rheumatology, Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Republic of Korea, ²Division of Rheumatology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea
Background/Purpose: Most women with systemic lupus erythematosus (SLE) are diagnosed with the disease in their reproductive ages, but the burden of SLE among women in…
Abstract Number: 2313 • 2019 ACR/ARP Annual Meeting
Patients with Rheumatoid Arthritis Have a Higher Risk of Bipolar Disorder: A Systematic Review and Meta-analysis
Patompong Ungprasert¹, Nipith Charoenngam ² and Ben Ponvilawan ², ¹Cleveland Clinic, Cleveland, OH, Bangkok, Thailand, ²Mahidol University, Bangkok, Thailand
Background/Purpose: Patients with chronic autoimmune diseases may have a higher risk of psychiatric illness as a result of chronic neuro-inflammation and immune dysregulation. The current…
Abstract Number: 2243 • 2018 ACR/ARHP Annual Meeting
Sex Difference of the Association between Serum Urate and Blood Pressure in Young Adults
Angelo Gaffo¹, Elizabeth J. Rahn², Tanja Dudenbostel¹, Amy S. Mudano¹, Peng Li³, David T. Redden³, Stephanie Biggers¹, Phillip J. Foster², Paul M. Muntner⁴, Suzanne Oparil⁵, David A. Calhoun⁵ and Kenneth Saag¹, ¹University of Alabama at Birmingham, Birmingham, AL, ²Department of Medicine, Division of Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ³Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, ⁴Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, ⁵Department of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Serum urate (sUA) has been associated with blood pressure in most but not all studies. This study aims to test whether there are sex…
Abstract Number: 2320 • 2018 ACR/ARHP Annual Meeting
Multimorbidity Is Associated with Hip Fractures in Both Women and Men and across Different Races
Shreyasee Amin¹, Elizabeth J. Atkinson² and Sundeep Khosla², ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Mayo Clinic, Rochester, MN
Background/Purpose: Multimorbidity, the coexistence of 2 or more chronic conditions, is associated with increased disability and poor functional status, and may serve as an important…
Abstract Number: 2507 • 2018 ACR/ARHP Annual Meeting
Healthcare Resource Utilization in Patients with Secondary Sjögren’s Syndrome Associated with RA Compared with Patients with RA in an Insured Population
Evo Alemao¹, Aarti Rao², Chidananda Samal² and Robert Wong¹, ¹Bristol-Myers Squibb, Princeton, NJ, ²Mu Sigma, Bangalore, India
Background/Purpose: Secondary Sjögren’s syndrome (sSS) is a rheumatic disease that may coexist with RA. Joint disease is more severe in patients (pts) with RA with…
Abstract Number: 325 • 2018 ACR/ARHP Annual Meeting
A Comparison of RADAI5 and RAPID3 Disease Measures
Ryan Jessee, Amanda M. Eudy and Megan E. B. Clowse, Department of Medicine, Division of Rheumatology and Immunology, Duke University, Durham, NC
Background/Purpose: Treat to target has been shown to improve outcomes in multiple rheumatology diseases although relies on accurate disease measures. Our academic clinic routinely measures…
Abstract Number: 2719 • 2018 ACR/ARHP Annual Meeting
Tracking the Risk of Infections in ANCA-Associated Vasculitis: Results from a Scottish Matched-Cohort Study
Shifa Sarica¹, Neeraj Dhaun², Jan Sznajd³, John Harvie³, Nicola Joss³, John McLaren⁴, Lucy McGeoch⁵, Nicole Amft⁶, Vinod Kumar⁷, Angharad Marks¹, Corri Black¹ and Neil Basu¹, ¹Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom, ²University/British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom, ³Department of Rheumatology, Raigmore Hospital, Inverness, United Kingdom, ⁴Fife Rheumatic Diseases Unit, Whyteman's Brae Hospital, Kirkcaldy, United Kingdom, ⁵Center for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, United Kingdom, ⁶Department of Rheumatology, Western General Hospital, Edinburgh, United Kingdom, ⁷Rheumatology Department, Ninewells Hospital, Dundee, United Kingdom
Background/Purpose: Evaluation of infection risk in ANCA-associated vasculitis (AAV) has been limited to small, selected populations and/or serious episodes. In this large study, we aimed…
Abstract Number: 332 • 2018 ACR/ARHP Annual Meeting
Components of Impaired Physical Function and Disability in a Non-Rheumatic Population. Normative Values of the Health Assessment Questionnaire Disability Index
C Alejandro Arce-Salinas¹, H FABRICIO ESPINOSA-ORTEGA² and Olivia Enriquez-Antonio³, ¹INTERNAL MEDICINE, Hospital Central Sur PEMEX, MEXICO, Mexico, ²Rheumatology Department, Karolinska Universitetssjukhuset, Stockolm, Sweden, ³Internal Medicine, Hospital Central Sur PEMEX, mexico, Mexico
Background/Purpose: HAQ-Di is broadly used to measure disability in RA, its assessment might influence taking decision process. However, it cannot differentiate disability related to arthritis,…
Abstract Number: 2768 • 2018 ACR/ARHP Annual Meeting
Comorbidity Accrual and Mortality in an Inception Cohort of Patients with Giant Cell Arteritis and Polymyalgia Rheumatica: A Single-Center, Observational Long-Term Study
Elisheva Pokroy-Shapira¹, Ariela Dortort-Lazar^2,3 and Yair Molad^4,5, ¹Rheumatology Unit, Rabin Medical Center, Beilinson Hospital and Sackler Faculty of Medicine, Tel Aviv University, Petach Tikva, Israel, ²Rheumatology Unit, Beilinson hospital Rabin Medical Center, Petah Tikva, Israel, ³Sackler Faculty of Medicine Tel Aviv university, Tel Aviv, Israel, ⁴Rheumatology Unit, Rabin Medical Center, Beilinson Hospital, Petach Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁵Rheumatology Unit, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel
Background/Purpose: Patients with giant-cell arteritis (GCA) and polymyalgia rheumatica (PMR) are treated with high cumulative glucocorticoid (GC) dose during their disease course. We sought to…

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