ACR Meeting Abstracts

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Abstracts tagged "Comorbidity"

  • Abstract Number: 0491 • ACR Convergence 2020

    Relationship Between Rheumatoid Arthritis and Pulmonary Function in the UK Biobank

    Lauren C. Prisco1, Matthew Moll1, Jiaqi Wang2, Weixing Huang3, Lily Martin1, Vanessa Kronzer4, Sicong Huang2, Edwin Silverman2, Tracy J. Doyle5, Michael Cho5 and Jeffrey Sparks6, 1Brigham and Women's Hospital, Boston, 2Brigham and Women's Hospital, Boston, MA, 3Division of Rheumatology, Inflammation, and Immunity; Brigham and Women’s Hospital and Harvard Medical School, Boston, 4Mayo Clinic, Rochester, MN, 5Brigham and Women's Hospital, West Roxbury, MA, 6Division of Rheumatology, Inflammation, and Immunity; Brigham and Women’s Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Established pulmonary manifestations of RA include restrictive processes such as interstitial lung disease and obstructive processes such as bronchiectasis, but clinically detected forms of…
  • Abstract Number: 1325 • ACR Convergence 2020

    Monoclonal Gammopathy in Psoriatic Arthritis

    Vanessa Ocampo1 and Dafna Gladman2, 1University of Toronto, University Health Network, Psoriatic Arthritis Research Program, Toronto, Canada, 2Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic premalignant clonal plasma disorder, defined by the presence of a serum monoclonal protein (M-protein) at…
  • Abstract Number: 0550 • ACR Convergence 2020

    Mapping Multimorbidity Using Drug Concept Unique Identifiers (RxCUIs) via the Rx-Risk Comorbidity Index

    Jared Vanderbleek1, Justin Owensby1, Alex Mccannaly1, Lang Chen1, Bryant England2, Jeffrey R Curtis3 and Huifeng Yun3, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Nebraska Medical Center, Omaha, NE, 3Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Identifying and accurately classifying comorbid conditions in large, real-world data sources is crucial for cohort establishment and confounder adjustment. However, the ability to conduct…
  • Abstract Number: 1327 • ACR Convergence 2020

    Comorbidity Burden in Patients with Non-Radiographic Axial Spondyloarthritis at Least as High as in Ankylosing Spondylitis

    Jonas Sagard1, Elisabet Lindqvist2, Elisabeth Mogard1, Anna Jöud3, Mats Geijer4, Tor Olofsson1 and Johan K. Wallman1, 1Department of Clinical Sciences Lund, Rheumatology, Lund University, Sweden. Department of Rheumatology, Skåne University Hospital, Lund, Sweden., Lund, Sweden, 2Department of Clinical Sciences Lund, Rheumatology, Lund University, Sweden. Department of Rheumatology, Skåne University Hospital. Lund, Sweden, Lund, Sweden, 3Department of Laboratory Medicine, Division of Occupational and Environmental Medicine, Lund University, Sweden., Lund, Sweden, 4Department of Radiology, Institute of Clinical Sciences, University of Gothenburg, Sahlgrenska Academy, Gothenburg, Sweden. Department of Radiology, Sahlgrenska University Hospital, Gothenburg, Sweden., Gothenburg, Sweden

    Background/Purpose: Few studies have investigated the overall occurrence of comorbidities in patients with non-radiographic axial spondyloarthritis (nr-axSpA) in relation to ankylosing spondylitis (AS). Compared to…
  • Abstract Number: 0558 • ACR Convergence 2020

    Statin Use Pattern in Patients with Inflammatory Joint Disease in a Single Site VA Medical Center

    Lenche Kostadinova1, Sofi Damjanovska2, Angela Gupta3, Ibtissam Gad4, Sameena Syed4, Alyssa Lange5, Corinne Kowal6, Carey Shive7, Christopher Burant4, Brigid Wilson4, David Canaday4, David Zidar8, Donald Anthony9 and Maya Mattar10, 1(1) Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Highland Heights, OH, 2(1) Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, OH, 3(1) Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, 4(1) Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, ohio, 5Case Western Reserve University, Cleveland, 6Case western reserve university/Cleveland VA Medical Center, ohio, 7(2) Department of Pathology, Case Western Reserve University, ohio, 8Case Western Reserve University/Cleveland VA Medical Center, Cleveland, 9Case Western Reserve University/Cleveland VA Medical Center/MetroHealth Medical Center, Cleveland, OH, 10Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, OH

    Background/Purpose: Patients with inflammatory joint disease, including rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS) carry increased risk of cardiovascular disease (CVD). Mechanisms…
  • Abstract Number: 1391 • ACR Convergence 2020

    Associations Between Autoantibodies in Systemic Sclerosis and Cancer in a National Registry

    Selma Lazizi1, Marie Hudson2, Murray Baron3, Marvin Fritzler4 and Sabrina Hoa5, 1Université de Montréal, Montreal, QC, Canada, 2Division of Rheumatology, Jewish General Hospital, Montréal, QC, Canada, 3Jewish General Hospital, Montreal, QC, Canada, 4Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 5Division of Rheumatology, Centre hospitalier de l'Université de Montréal, Montréal, QC, Canada

    Background/Purpose: Autoantibodies are useful in systemic sclerosis (SSc) for predicting disease course. Some autoantibodies have been associated with a close temporal relationship with cancer. We…
  • Abstract Number: 0661 • ACR Convergence 2020

    Genomic Regions Jointly Associated with eGFR and Serum Urate: Implications for Shared Genetic Etiology of Hyperuricemia and Chronic Kidney Disease

    Nick Sumpter1, Alexa Lupi2, Megan Leask3, Tony Merriman4, Ana Vazquez2 and Richard Reynolds1, 1University of Alabama at Birmingham, Birmingham, AL, 2Michigan State University, East Lansing, MI, 3University of Otago, Dunedin, Otago, New Zealand, 4University of Otago, Dunedin, New Zealand

    Background/Purpose: Gout and hyperuricemia (HU), serum urate (SU) > 6.8 mg/dL, often present in the context of chronic kidney disease. It has long been known…
  • Abstract Number: 1433 • ACR Convergence 2020

    Thyroid Disease in ANCA-associated Vasculitis. a Population-based Study

    Anna Wilding1, Rona Smith2, David Jayne3, Mårten Segelmark4 and Aladdin Mohammad5, 1Lund University, Staffanstorp, Sweden, 2University of Cambridge, Cambridge, United Kingdom, 3Department of Medicine, Vasculitis and Lupus Research Group, University of Cambridge, Cambridge, UK, Cambridge, United Kingdom, 4Lund University, Lund, 5Lund University, Lund, Sweden. Department of Medicine, Vasculitis and Lupus Research Group, University of Cambridge, Cambridge, UK, Lund, Sweden

    Background/Purpose: A higher incidence of thyroid disease has been seen in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). We aim to assess the incidence…
  • Abstract Number: 0002 • ACR Convergence 2020

    Hydroxychloroquine and Chloroquine and Hospitalizations for Viral Infection in the Pre-COVID-19 Era

    Cristiano Moura1, Marina Machado1, Celline Almeida-Brasil1, Jeffrey R Curtis2, Kevin Winthrop3, Michal Abrahamowicz1 and Sasha Bernatsky4, 1McGill University, Montreal, Canada, 2Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 3Oregon Health & Science University, Portland, OR, 4The Research Institute of the McGill University Health Centre, Montreal, ON, Canada

    Background/Purpose: Chloroquine (CQ) and hydroxychloroquine (HCQ) have been shown to have antiviral properties and were considered as potential therapeutic options amid the COVID-19 pandemic. The…
  • Abstract Number: 0663 • ACR Convergence 2020

    Analysis of Common Gout Comorbidities in the UK Biobank Cohort Reveals Sex-Specific Effects and Genetic Differentiation

    Nicholas Sumpter1, Murray Cadzow2, Alexander So3, Richard Reynolds1 and Tony Merriman2, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Otago, Dunedin, New Zealand, 3University of Lausanne, Lausanne, Switzerland

    Background/Purpose: This study aimed to estimate the extent to which gout associated genetic variants are associated with the presence/absence of common comorbidities in gout patients…
  • Abstract Number: 1449 • ACR Convergence 2020

    Altered Splicing in Leukocytes from Patients with Antiphospholipid Syndrome, Systemic Lupus Erythematosus and Antiphospholipid Syndrome with Lupus: Clinical Involvement

    Alejandra Maria Patiño-Trives1, Alejandro Ibáñez-Costa2, Carlos Pérez-Sánchez1, Laura Pérez-Sanchez3, Maria Luque-Tevar1, Iván Arias de la Rosa1, María-Carmen Abalos-Aguilera1, Desirée Ruiz-Vilchez4, Pedro Segui5, Mario Espinosa5, Nuria Barbarroja1, Eduardo Collantes4, Justo P. Castaño5, Raul M Luque5, María de los ángeles Aguirre-Zamorano5 and Chary Lopez-Pedrera1, 1Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Cordoba, Spain, 2IMIBIC/University of Cordoba/Reina Sofia Hospital, Córdoba, 3Hospital Universitario Reina Sofía, Córdoba, Spain, 4Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Córdoba, Spain, 5IMIBIC/University of Cordoba/Reina Sofia Hospital, Cordoba

    Background/Purpose: To identify shared and differential changes in the splicing machinery of immune cells from antiphospholipid syndrome (APS), systemic lupus erythematosus (SLE) and antiphospholipid syndrome…
  • Abstract Number: 0177 • ACR Convergence 2020

    Association of Hydroxychloroquine Use with Development of Non-Alcoholic Fatty Liver Disease in Rheumatoid Arthritis

    Nicholas Wiemer1, Rebecca Schorr2, Mary Chester Wasko3 and Tarun Sharma1, 1Allegheny Health Network, Pittsburgh, PA, 2Highmark, Pittsburgh, PA, 3Allegheny Health Network, West Penn Hospital, Pittsburgh, PA

    Background/Purpose: Non-alcoholic fatty liver disease (NAFLD), the most common form of liver disease, refers to a spectrum of conditions which includes non-alcoholic fatty liver (NAFL),…
  • Abstract Number: 0678 • ACR Convergence 2020

    Patient Characteristics and Patterns of Urate-lowering Treatments in Older Patients with Incident Gout

    Kazuki Yoshida1, Jun Liu2, Daniel H Solomon3 and Seoyoung Kim3, 1Brigham & Women's Hospital and Harvard Medical School, Boston, MA, 2Brigham and Women's Hospital, Boston, 3Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Gout is a common inflammatory arthritis caused by monosodium urate crystal deposition in the joints.  Despite this well-understood pathophysiologic mechanism of disease and ACR and EULAR…
  • Abstract Number: 1466 • ACR Convergence 2020

    Multimorbidity in Rheumatoid Arthritis, Psoriatic Arthritis, Gout, and Osteoarthritis Within the Rheumatology Informatics System for Effectiveness (RISE) Registry

    Bryant England1, Huifeng Yun2, Lang Chen3, Kaleb Michaud1, Ted Mikuls1 and Jeffrey R Curtis2, 1University of Nebraska Medical Center, Omaha, NE, 2Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 3University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Rheumatic and musculoskeletal diseases (RMDs) often predispose the development of other chronic conditions, resulting in multimorbidity. While multimorbidity is increasingly being recognized and examined…
  • Abstract Number: 0178 • ACR Convergence 2020

    Associations of Multimorbidity with DMARD Initiation and Achieving Target Disease Activity Thresholds in Active Rheumatoid Arthritis: A Cohort Study Using the Rheumatology Informatics System for Effectiveness (RISE) Registry

    Bryant England1, Huifeng Yun2, Lang Chen3, Kaleb Michaud1, Ted Mikuls1 and Jeffrey R Curtis2, 1University of Nebraska Medical Center, Omaha, NE, 2Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 3University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Although a treat-to-target strategy is endorsed in rheumatoid arthritis (RA) treatment guidelines, its routine implementation in real-world settings, particularly in the context of multimorbidity,…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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