Abstracts tagged "Cognitive dysfunction"

Abstract Number: 785 • 2016 ACR/ARHP Annual Meeting
What Is the Prevalence of Cognitive Impairment in Lupus and Which Instruments Are Used to Measure It? a Systematic Review and Meta-Analysis
Hanan Al Rayes¹, Chiara Tani², Marta Mosca², Jorge Medina-Rosas³, Ahmed Moustafa⁴, Panayiotis Lambiris⁵ and Zahi Touma¹, ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Clinical and Experimental Medicine, University of Pisa, Rheumatology Unit, Pisa, Italy, ³Medicine, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴Medicine, Western University, London, ON, Canada, ⁵University Health Network, Toronto, ON, Canada
Background/Purpose: To systematically review literature on: 1) the prevalence of Cognitive Impairment (CI) in SLE patients in the presence or absence of neuropsychiatric involvement (NPSLE),…
Abstract Number: 1396 • 2016 ACR/ARHP Annual Meeting
Cognitive Function in Children with SLE Nephritis: A Cross-Sectional Comparison to Children with Other Glomerular Chronic Kidney Diseases
Andrea Knight^1,2,3, Matthew Matheson⁴, Susan Furth⁵, Brad Warady⁶, Stephen Hooper⁷ and Amy Kogon⁸, ¹Division of Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²PolicyLab, Children's Hospital of Philadelphia, Philadelphia, PA, ³Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA, ⁴Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ⁵Division of Nephrology, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ⁶Division of Nephrology, Children's Mercy Hospital, Kansas City, MO, ⁷Department of Allied Health Sciences, University of North Carolina School of Medicine, Chapel Hill, NC, ⁸Division of Nephrology, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH
Background/Purpose: Children with lupus nephritis (LN) are at risk for cognitive impairment due to effects on the brain from systemic inflammation and from potential effects…
Abstract Number: 2205 • 2016 ACR/ARHP Annual Meeting
Cognitive Functioning in Fibromyalgia: The Central Role of Effort
Jacob Ablin¹, Tamar Bar On –Kalfon², Gilad Gal³ and Ran Shorer², ¹Rheumatology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel, ²Rheumatology, Tel Aviv Sourasky medical center, Tel Aviv, Israel, ³School of Behavioral Sciences, Tel Aviv-Jaffa Academic College, Tel Aviv, Israel
Background/Purpose: Fibromyalgia syndrome (FMS) patients demonstrate deficits in tests of attention, executive functioning and verbal memory. We assessed the role of effort in the cognitive…
Abstract Number: 63 • 2015 ACR/ARHP Annual Meeting
Association of Smoking and Cognitive Function in Patients with Fibromyalgia
Lin Ge^1,2, Terry H. Oh³, Ann Vincent⁴, Arya Mohabbat⁵, li Jiang⁶, Mary Whipple⁷, Samantha McAllister⁸, Zhen Wang⁹ and WenChun Qu¹⁰, ¹Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, ²Rheumatology, Guang An Men Hospital, China Academy of Chinese Medical Science,, Beijing, China, ³Physical Medicine & Rehabilitation, Mayo Clinic, Rochester, MN, ⁴General Internal Medicine, Mayo Clinic, Rochester, MN, ⁵Department of Medicine, Mayo Clinic, Rochester, MN, ⁶Rehabilitation, The Third Affiliated Hospital，Sun Yat-sen University,China, Guangzhou, China, ⁷Fibromyalgia and Chronic Fatigue Clinic, Mayo Clinic, Rochester, MN, ⁸Mayo Clinic, Rochester, MN, ⁹Health Sciences Research, Mayo Clinic, Rochester, MN, ¹⁰Department Physical Medicine and Rehabilitation, Department of Anesthesiology Division of Pain Medicine, Mayo Clinic, Rochester, MN
Background/Purpose: To evaluate the association between smoking and cognitive function in patients with fibromyalgia (FM). Methods: We surveyed 668 patients with FM from May 2012…
Abstract Number: 2045 • 2015 ACR/ARHP Annual Meeting
Cross-Validation of the Pediatric Automated Neuropsychological Assessment Metrics-Cognitive Performance Scores in the Screening of Neurocognitive Impairment in Childhood-Onset Systemic Lupus Erythematosus
Jasmine Nguyen¹, Tricia Williams², Earl Silverman³ and Deborah M. Levy⁴, ¹Royal College of Surgeons in Ireland, Dublin, Ireland, ²Psychology, Hospital for Sick Children, Toronto, ON, Canada, ³Division of Rheumatology, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ⁴Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Neurocognitive impairment (NCI) is an important morbidity in childhood-onset systemic lupus erythematosus (cSLE); however, the gold standard formal neuropsychological assessment is difficult to access. Screening for…
Abstract Number: 2476 • 2015 ACR/ARHP Annual Meeting
Patient-Reported Cognitive Impairment, Pain, and Depressive Symptoms in Patients with Systemic Lupus Erythematosus and Comorbid Depression
Kelly Beck¹, Xing Gao², Yu Cheng³ and Carol M. Greco⁴, ¹School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, PA, ²Biostatistics, University of Pittsburgh, Pittsburgh, PA, ³Biostatistics and Psychiatry, University of Pittsburgh, Pittsburgh, PA, ⁴University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Patients with systemic lupus erythematosus (SLE) frequently report cognitive impairment as well as depressive symptoms and significant pain. However, depression criteria and SLE symptoms…
Abstract Number: 2923 • 2015 ACR/ARHP Annual Meeting
The Effects of Disease Activity and Mood Disorders on Cognitive Function in Systemic Lupus Erythematosus
Michelle Barraclough^1,2, Rebecca Elliott^2,3, Shane McKie^2,3, Ben Parker^1,2 and Ian N. Bruce^1,2, ¹Stopford Building, Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, ²Central Manchester University Hospital NHS Foundation Trust and Manchester Academic Health Science Centre, NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester, United Kingdom, ³Stopford Building, Neuroscience and Psychiatry Unit, Institute of Brain and Behaviour and Mental Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom
Background/Purpose: Cognitive dysfunction (CD) significantly affects SLE patients with many contributing causal factors. The effect of disease activity on cognitive function remains unclear and currently…
Abstract Number: 2951 • 2015 ACR/ARHP Annual Meeting
Anti-NR2 Antibody and Blood-Brain Barrier Disruption in Systemic Lupus Erythematosus Patients with Cognitive Dysfunction
Gaurav Gulati¹, Philip Iffland², Damir Janigro², Bin Zhang³ and Michael Luggen⁴, ¹Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH, ²Cleveland Clinic Lerner College of Medicine, Cleveland, OH, ³Cincinnati Children's Hospital and Medical Center, Cincinnati, OH, ⁴Division of Immunology, University of Cincinnati Medical Center, Cincinnati, OH
Background/Purpose: Cognitive Dysfunction (CD) is one of the most common manifestations of neuropsychiatric SLE (NPSLE) and one of the most devastating. The pathogenesis of CD…
Abstract Number: 2958 • 2015 ACR/ARHP Annual Meeting
Vitamin D, Cognition and Cerebral Structural Abnormalities in Childhood- Onset Systemic Lupus Erythematosus
Nailu A. Sinicato¹, Mariana Postal², Aline Tamires Lapa², Bruna B Siqueira³, Karina Pelicari², Paula T Fernades³, Roberto Marini Sr.⁴ and Simone Appenzeller⁵, ¹Pediatrics, State University of Campinas, Campinas, Brazil, ²Medicine, State University of Campinas, Campinas, Brazil, ³State University of Campinas, Campinas, Brazil, ⁴Pediatric Rheumatology Unit, State University of Campinas, São Paulo, Brazil, ⁵Division of Rheumatology, Faculty of Medical Science, State University of Campinas, São Paulo, Brazil
Background/Purpose: About 16-95% of SLE patients have vitamin D insufficiency. Vitamin D levels, especially vitamin D deficiency, are associated with cognitive performance in adults. We…
Abstract Number: 2959 • 2015 ACR/ARHP Annual Meeting
Patterns of Vascular Brain Injury in Systemic Lupus Erythematosus Patients with Ischemic Stroke: Impact on Neuropsychological, Neurobehavioral and Physical Function Outcome
Jamal A. Mikdashi¹, Marcia Wozniak², Umran Ashraf³ and William Regenold⁴, ¹Div of Rheumatology, Univ of Maryland Schl of Med, Baltimore, MD, ²Neurology, University of Maryland School of Medicine, Baltimore, MD, ³Radiology, University fo Maryland, Baltimore, MD, ⁴Psychiatry, Univeristy of Maryland School of Medicine, Baltimore, MD
Background/Purpose: Ischemic strokes in Systemic lupus erythematosus (SLE) patients contribute to increased morbidity and mortality. Little is known however, about the patterns of ischemic brain…
Abstract Number: 3123 • 2015 ACR/ARHP Annual Meeting
Evidence of Altered Blood Brain Barrier Permeability in Systemic Lupus Erythematosus Using Magnetic Resonance Imaging
Gaurav Gulati¹, Jordan T. Jones², Mekibib Altaye³, Jamie Meyers Eaton⁴, Kasha Wiley², Mark DiFrancesco⁵ and Hermine I. Brunner⁶, ¹Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH, ²Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Biostatistics and Epidemiology, Cincinnati Children's Hospital and Medical Center, Cincinnati, OH, ⁴Division of Pediatric Rheumatology, Cincinnati Children's Hospital and Medical Center, Cincinnati, OH, ⁵Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁶Pediatric Rheumatology Collaborative Study Group, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Neurocognitive dysfunction is a common manifestation of childhood-onset Systemic Lupus Erythematosus (cSLE). Murine models suggest that loss of the blood-brain barrier (BBB) integrity allows…
Abstract Number: 2916 • 2014 ACR/ARHP Annual Meeting
Effects of Exercise on Body Composition, Cardiovascular Fitness, Muscle Strength, and Cognition in Patients with Rheumatoid Arthritis: A Randomised Controlled Trial of a Patient-Specific Exercise Programme
Maha Azeez¹, Ciara Clancy², Tom O'Dwyer³, Fiona Wilson³ and Gaye Cunnane⁴, ¹Rheumatology, St James's Hospital and Trinity College Dublin, Dublin, Ireland, ²Department of Physiotherapy, Trinity College Dublin, Dublin, Ireland, ³Physiotherapy, Trinity College Dublin, Dublin, Ireland, ⁴Dept of Rheumatology, St James's Hospital and Trinity College Dublin, Dublin, Ireland
Background/Purpose Rheumatoid Arthritis (RA) patients have lower levels of physical activity compared to their non-RA counterparts. Large proportions of patients with RA are overweight or…
Abstract Number: 2654 • 2014 ACR/ARHP Annual Meeting
Cognitive Function in Systemic Lupus Erythematosus Patients with Past History of Neuropsychiatric Manifestations : A Longitudinal Study
Yang Gao¹, Yi Lo¹, Jacky Wan², Esther YY Lau² and Mo Yin Mok¹, ¹Department of Medicine, University of Hong Kong, Hong Kong, Hong Kong, ²Department of Psychology, University of Hong Kong, Hong Kong, Hong Kong
Background/Purpose: Cognitive impairment is commonly reported in patients with systemic lupus erythematosus (SLE) and its associations with neuropsychiatric involvement (NPSLE) and psychiatric factors have been…
Abstract Number: 2660 • 2014 ACR/ARHP Annual Meeting
Metabolic Syndrome Features Can Influenciate Cognitive Functions and Brain Lesions in Childhood-Onset Systemic Lupus Erythematosus
Nailu A. Sinicato¹, Aline T. Lapa¹, Mariana Postal¹, Bruna Bellini¹, Paula T Fernandes², Roberto Marini³ and Simone Appenzeller⁴, ¹Medicine, State University of Campinas, Campinas, Brazil, ²Faculty of Physical Education, State University of Campinas, Campinas, Brazil, ³Departament of Pediatrics, State University of Campinas, Campinas, Brazil, ⁴Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil
Background/Purpose: The underlying factor for an association between the metabolic syndrome (MetS) and cognitive decline might be a subclinical inflammation. Inflammatory mechanisms are hypothesized to…
Abstract Number: 2658 • 2014 ACR/ARHP Annual Meeting
Cognitive Symptoms and Associated Disease and Non-Disease Related Factors in Patients with Systemic Lupus Erythematosus : A Longitudinal Study
Yang Gao, Yi Lo and Mo Yin Mok, Department of Medicine, University of Hong Kong, Hong Kong, Hong Kong
Background/Purpose: Cognitive impairment is commonly reported in patients with systemic lupus erythematosus (SLE). Its associated disease and non-disease related factors have been inconsistently reported. Objective:…

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