ACR Meeting Abstracts

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Abstracts tagged "Clinical"

  • Abstract Number: 734 • 2015 ACR/ARHP Annual Meeting

    Disease Patterns, Flare Incidence and Organ Damage Among Filipino Patients with Systemic Lupus Erythematosus: a One-Year Observational Study

    Mary Flor Joy Edar, Leonid Zamora, Catherine Macapagal and Sandra V. Navarra, Rheumatology, University of Santo Tomas Hospital, Manila, Philippines

    Background/Purpose: This study describes the disease patterns, flare incidence, hospitalizations and causes of mortality in a cohort of Filipino patients with systemic lupus erythematosus (SLE),…
  • Abstract Number: 744 • 2015 ACR/ARHP Annual Meeting

    Longitudinal Assessment of Th1 and Th2 Cytokines: A Comparison Between Adult-Onset and Childhood-Onset Systemic Lupus Erythematous

    Karina Pelicari1, Mariana Postal1, Nailu A. Sinicato2, Fernando A. Peres1, Roberto Marini Sr.3, Lilian Tereza Costallat4 and Simone Appenzeller5, 1Medicine, State University of Campinas, Campinas, Brazil, 2Pediatrics, State University of Campinas, Campinas, Brazil, 3Pediatric Rheumatology Unit, State University of Campinas, São Paulo, Brazil, 4RUA EZEQUIEL MAGALHAES,26, Unicamp, Campinas, Brazil, 5Division of Rheumatology, Faculty of Medical Science, State University of Campinas, São Paulo, Brazil

    Background/Purpose: The clinical presentation may be different between adult-onset SLE (aSLE) and childhood-onset SLE (cSLE). The profile of cytokine may the clarify of SLE pathophysiology. The…
  • Abstract Number: 943 • 2015 ACR/ARHP Annual Meeting

    Development of an Internationally Agreed Minimal Dataset for Juvenile Dermatomyositis (JDM) for Clinical and Research Use

    Liza J. McCann1, Lucy R Wedderburn2, Clarissa Pilkington3, Adam M. Huber4, Angelo Ravelli5, Jamie Kirkham6, Paula Williamson6 and Michael W. Beresford7, 1Paediatric Rheumatology, Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom, 2Infection, Inflammation and Rheumatology Section, UCL Institute for Child Health, London, United Kingdom, 3Department of Rheumatology, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom, 4Pediatric rheumatology, IWK Health Centre, Halifax, NS, Canada, 5Pediatria-II, IRCCS G. Gaslini and University of Genova, Genova, Italy, 6Department of Biostatistics, University of Liverpool, MRC North West Hub for Trials Methodology Research, Liverpool, United Kingdom, 7Alder Hey Children's NHS Foundation Trust Hospital, Institute of Translational Medicine (Child Health), University of Liverpool, Liverpool, United Kingdom

    Background/Purpose: Juvenile dermatomyositis (JDM) is a rare disease. International collaboration is essential for scrutiny of sufficient patient numbers. We aim to develop a core set…
  • Abstract Number: 950 • 2015 ACR/ARHP Annual Meeting

    In a Two-Year Double-Blind Randomized Controlled Multicenter Study, Chondroitin Sulfate Was Significantly Superior to Celecoxib at Reducing Cartilage Loss with Similar Efficacy at Reducing Disease Symptoms in Knee Osteoarthritis Patients

    Jean-Pierre Pelletier1, Jean Pierre Raynauld2, André Beaulieu3, Louis Bessette4, Frédéric Morin5, Artur J Fernandes6, François Abram7, Marc Dorais8 and Johanne Martel-Pelletier9, 1Rheumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada, 2Osteoarthritis Research Unit, CRCHUM, Montreal, Montreal, QC, Canada, 3Centre de rhumatologie St-Louis, St. Louis, QC, Canada, 4Groupe de Recherche en Rhumatologie et Maladies Osseuses, Quebec, Quebec, QC, Canada, 5Centre de Recherche Musculo-squelettique, Trois-Rivières, Trois-Rivières, QC, Canada, 6Centre de Recherche Musculo-squelettique, Trois-Rivières, 6Rheumatology Division, Sherbrooke, Sherbrooke, QC, Canada, 7Medical Imaging Research & Development, ArthroLab Inc, Montreal, QC, Canada, 8StatSciences Inc., Montreal, Canada, Montreal, QC, Canada, 9Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM),, Montreal, QC, Canada

    Background/Purpose: In osteoarthritis (OA) treatment, although chondroitin sulfate (CS) was found in a number of studies using radiography to have a structure modifying effect, to…
  • Abstract Number: 1642 • 2015 ACR/ARHP Annual Meeting

    A Systematic Review and Network Meta-Analysis on the Efficacy of Tumor Necrosis Factor Inhibitor-Methotrexate Combination Therapy Versus Triple Therapy in Methotrexate Inadequate Responders with Rheumatoid Arthritis

    Roy Fleischmann1, Janet E. Pope2, Vanita Tongbram3, Derek Tang4, James Chung5, David Collier5, Shilpa Urs3, Kerigo Ndirangu3, George A. Wells6 and Ronald F. van Vollenhoven7, 1Rheumatology, Metroplex Clinical Research Center, Dallas, TX, 2University of Western Ontario, London, ON, Canada, 3ICON Plc., Morristown, NJ, 4Amgen, Inc., Thousand Oaks, CA, 5Amgen Inc., Thousand Oaks, CA, 6Cardiovascular Research Reference Centre, University of Ottawa Heart Institute, Ottawa, ON, Canada, 7Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden

    Background/Purpose: Previously published rheumatoid arthritis (RA) trials in which TNFi-MTX and triple therapy (MTX + hydroxychloroquine + sulfasalazine) were included as treatment arms in MTX…
  • Abstract Number: 1654 • 2015 ACR/ARHP Annual Meeting

    A Systematic Review and Network Meta-Analysis on the Efficacy of Tumor Necrosis Factor Inhibitor-Methotrexate Combination Therapy Versus Triple Therapy in Methotrexate-Naïve Patients with Rheumatoid Arthritis

    Roy Fleischmann1, Janet E. Pope2, Vanita Tongbram3, Derek Tang4, James Chung5, David Collier5, Shilpa Urs3, Kerigo Ndirangu3, George A. Wells6 and Ronald F. van Vollenhoven7, 1University of Texas Southwestern Medical Center, Dallas, TX, 2University of Western Ontario, London, ON, Canada, 3ICON Plc., Morristown, NJ, 4Amgen, Inc., Thousand Oaks, CA, 5Amgen Inc., Thousand Oaks, CA, 6Cardiovascular Research Reference Centre, University of Ottawa Heart Institute, Ottawa, ON, Canada, 7Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden

    Background/Purpose: Several published randomized head-to-head trials in rheumatoid arthritis (RA) have compared TNFi-MTX with triple therapy (MTX + hydroxychloroquine + sulfasalazine) in MTX-naive patients (MTX-Ns)…
  • Abstract Number: 791 • 2014 ACR/ARHP Annual Meeting

    Comparison of Clinical Manifestations in Different Histological Subsets of Biopsy-Proven Giant Cell Arteritis

    Luigi Boiardi1, Francesco Muratore1, Alberto Cavazza2, Giovanna Restuccia3, Pierluigi Macchioni1, Giuseppe Germanò1, Nicolò Pipitone1, Gianluigi Bajocchi4 and Carlo Salvarani1, 1Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 2Pathology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 3Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 4Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Japan

    Background/Purpose: Temporal artery biopsy (TAB) showing transmural inflammation is considered the gold standard for the diagnosis of giant cell arteritis (GCA). In some cases of…
  • Abstract Number: 790 • 2014 ACR/ARHP Annual Meeting

    Correlations Between Histopathological Findings and Clinical Manifestations in a Large Monocentric Cohort of Patients with Biopsy-Proven Giant Cell Arteritis

    Luigi Boiardi1, Francesco Muratore1, Giovanna Restuccia2, Alberto Cavazza3, Pierluigi Macchioni1, Giuseppe Germanò1, Nicolò Pipitone1 and Carlo Salvarani1, 1Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 2Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 3Pathology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy

    Background/Purpose: Giant cell arteritis (GCA) is a vasculitis that involves large and medium sized arteries in patients older than 50 years. Temporal artery biopsy (TAB)…
  • Abstract Number: 789 • 2014 ACR/ARHP Annual Meeting

    Association Between Histological Features and Clinical Features of Patients with Biopsy Positive Giant Cell Arteritis

    Kimberley Ting1, Susan Lester2 and Catherine L. Hill3, 1Rheumatology, The Queen Elizabeth Hospital, Adelaide, Australia, 2Rheumatology Unit, Queen Elizabeth Hospital, Woodville South, Australia, 3Discipline of Medicine, University of Adelaide, Adelaide, Australia

    Background/Purpose: Temporal artery biopsy is the gold standard for diagnosing giant cell arteritis (GCA). The pathology of GCA characteristically involves transmural infiltrates, giant cell formation…
  • Abstract Number: 722 • 2014 ACR/ARHP Annual Meeting

    Prediction of Improvement in Skin Fibrosis in Diffuse Cutaneous Systemic Sclerosis

    Rucsandra Dobrota1,2, Britta Maurer1, Nicole Graf3, Carina Mihai2, Otylia Kowal-Bielecka4, Yannick Allanore5 and Oliver Distler on behalf of the EUSTAR investigators and co-authors1, 1Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 2Department of Internal Medicine and Rheumatology, Dr.I.Cantacuzino Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, 3graf biostatistics, Winterthur, Switzerland, 4Department of Rheumatology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland, 5Department of Rheumatology, University Paris Descartes and Cochin Hospital, Paris, France

    Background/Purpose Improvement of skin fibrosis over time is part of the “natural history” of patients with diffuse cutaneous systemic sclerosis (dcSSc). However, in the individual…
  • Abstract Number: 587 • 2014 ACR/ARHP Annual Meeting

    Clinical Characteristics of Nonradiographic Axial Spondyloarthritis in Korea: A Comparison with Ankylosing Spondylitis

    Hyungjin Kim1, Hyemin Jeong1, Seulkee Lee1, Inyoung Kim1, Jiwon Hwang2, Jaejoon Lee1, Jinseok Kim3, Eun-Mi Koh4 and Hoon-Suk Cha5, 1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 2Department of Medicine,Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 31753-3, Ara-1 Dong, Jeju National University Hospital, Jeju, South Korea, 4Dept of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 5Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea

    Background/Purpose: To evaluate the clinical characteristics and outcomes of nonradiographic axial spondyloarthritis (nr-axSpA) in Korean patients. Methods: A retrospective analysis evaluated 155 patients with nr-axSpA…
  • Abstract Number: 198 • 2014 ACR/ARHP Annual Meeting

    Implant Survival and Patient-Reported Outcomes after Total Hip Arthroplasty in Young Patients with JIA

    Ishaan Swarup1, Ella Christoph1, Lisa A. Mandl2, Susan M. Goodman2 and Mark P. Figgie3, 1Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, 2Rheumatology, Hospital for Special Surgery, New York, NY, 3Orthopedics, Hospital for Special Surgery, New York, NY

    Background/Purpose :  Juvenile Idiopathic Arthritis (JIA) is a common rheumatologic disease in children that often persists into adulthood.  The hip joint is commonly involved, and…
  • Abstract Number: 74 • 2014 ACR/ARHP Annual Meeting

    Influence of the Polymorphism IL1ß (-511 A/C) and IL6 (- 174 G/C) on the Activity, Radiographic Damage and Clinical Forms of Patients with Psoriatic Arthritis (PSA)

    Tatiana Carranco1, Noelia Cubino2, Clara Cieza-Borrela3, Ismael Calero3, Maria Dolores Sanchez3, C. Hidalgo-Calleja4, Alba Quesada3, Andres Plata3, Agustin Diaz Alvarez3, Ricardo Usategui5, Rogelio Gonzalez5, C.a. Montilla-Morales4 and J. Del Pino-Montes4, 1Reumathology, HOSPITAL CLINICO UNIVERSITARIO DE SALAMANCA, SALAMANCA, Spain, 2INTERNAL MEDICINE, HOSPITAL CLINICO UNIVERSITARIO DE SALAMANCA, SALAMANCA, Spain, 3HOSPITAL CLINICO UNIVERSITARIO DE SALAMANCA, SALAMANCA, Spain, 4University of Salamanca Hospital, Salamanca, Spain, 5IBSAL, SALAMANCA, Spain

    Background/Purpose: PSA is a chronic inflammatory disease associated to psoriasis which affects the joints, vertebrae and enthesis. Interleukin-1 is an inflammatory cytokine. A higher expression…
  • Abstract Number: L6 • 2014 ACR/ARHP Annual Meeting

    A PHASE 2, Randomized, Double-Blind Comparison of the Efficacy and Safety of PF-04171327 (1, 5, 10, 15 mg QD) Vs 5 and 10 Mg Prednisone QD or Placebo in Subjects with Rheumatoid Arthritis (RA) over 8 Weeks Followed By a 4-Week Taper of Study Drug

    Vibeke Strand1, Frank Buttgereit2, Dorothy McCabe3, Sheela Kolluri3, Brinda Tammara3, Ricardo Rojo3 and Judith Hey-Hadavi3,4, 1Biopharmaceutical Consultant, Portola Valley, CA, 2Charité University Hospital, Berlin, Germany, 3Pfizer Inc, New York, NY, 4Pfizer Inc, NewYork, NY

    Background/Purpose: PF-04171327 is a dissociated agonist of the glucocorticoid receptor (DAGR), a selective high-affinity partial agonist of the GR with potent anti-inflammatory activity at exposures…
  • Abstract Number: 2904 • 2014 ACR/ARHP Annual Meeting

    Clinical and Radiological Features of Down’s Arthropathy

    Charlene Foley, Orla Killeen and Emma Jane MacDermott, The National Centre for Paediatric Rheumatology, Dublin, Ireland

    Background/Purpose The ‘Arthropathy of Down syndrome’ was first described in 1984. Three decades on we still have limited literature on the clinical & radiological features…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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