ACR Meeting Abstracts

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Abstracts tagged "Clinical"

  • Abstract Number: 943 • 2015 ACR/ARHP Annual Meeting

    Development of an Internationally Agreed Minimal Dataset for Juvenile Dermatomyositis (JDM) for Clinical and Research Use

    Liza J. McCann1, Lucy R Wedderburn2, Clarissa Pilkington3, Adam M. Huber4, Angelo Ravelli5, Jamie Kirkham6, Paula Williamson6 and Michael W. Beresford7, 1Paediatric Rheumatology, Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom, 2Infection, Inflammation and Rheumatology Section, UCL Institute for Child Health, London, United Kingdom, 3Department of Rheumatology, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom, 4Pediatric rheumatology, IWK Health Centre, Halifax, NS, Canada, 5Pediatria-II, IRCCS G. Gaslini and University of Genova, Genova, Italy, 6Department of Biostatistics, University of Liverpool, MRC North West Hub for Trials Methodology Research, Liverpool, United Kingdom, 7Alder Hey Children's NHS Foundation Trust Hospital, Institute of Translational Medicine (Child Health), University of Liverpool, Liverpool, United Kingdom

    Background/Purpose: Juvenile dermatomyositis (JDM) is a rare disease. International collaboration is essential for scrutiny of sufficient patient numbers. We aim to develop a core set…
  • Abstract Number: 950 • 2015 ACR/ARHP Annual Meeting

    In a Two-Year Double-Blind Randomized Controlled Multicenter Study, Chondroitin Sulfate Was Significantly Superior to Celecoxib at Reducing Cartilage Loss with Similar Efficacy at Reducing Disease Symptoms in Knee Osteoarthritis Patients

    Jean-Pierre Pelletier1, Jean Pierre Raynauld2, André Beaulieu3, Louis Bessette4, Frédéric Morin5, Artur J Fernandes6, François Abram7, Marc Dorais8 and Johanne Martel-Pelletier9, 1Rheumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada, 2Osteoarthritis Research Unit, CRCHUM, Montreal, Montreal, QC, Canada, 3Centre de rhumatologie St-Louis, St. Louis, QC, Canada, 4Groupe de Recherche en Rhumatologie et Maladies Osseuses, Quebec, Quebec, QC, Canada, 5Centre de Recherche Musculo-squelettique, Trois-Rivières, Trois-Rivières, QC, Canada, 6Centre de Recherche Musculo-squelettique, Trois-Rivières, 6Rheumatology Division, Sherbrooke, Sherbrooke, QC, Canada, 7Medical Imaging Research & Development, ArthroLab Inc, Montreal, QC, Canada, 8StatSciences Inc., Montreal, Canada, Montreal, QC, Canada, 9Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM),, Montreal, QC, Canada

    Background/Purpose: In osteoarthritis (OA) treatment, although chondroitin sulfate (CS) was found in a number of studies using radiography to have a structure modifying effect, to…
  • Abstract Number: 1642 • 2015 ACR/ARHP Annual Meeting

    A Systematic Review and Network Meta-Analysis on the Efficacy of Tumor Necrosis Factor Inhibitor-Methotrexate Combination Therapy Versus Triple Therapy in Methotrexate Inadequate Responders with Rheumatoid Arthritis

    Roy Fleischmann1, Janet E. Pope2, Vanita Tongbram3, Derek Tang4, James Chung5, David Collier5, Shilpa Urs3, Kerigo Ndirangu3, George A. Wells6 and Ronald F. van Vollenhoven7, 1Rheumatology, Metroplex Clinical Research Center, Dallas, TX, 2University of Western Ontario, London, ON, Canada, 3ICON Plc., Morristown, NJ, 4Amgen, Inc., Thousand Oaks, CA, 5Amgen Inc., Thousand Oaks, CA, 6Cardiovascular Research Reference Centre, University of Ottawa Heart Institute, Ottawa, ON, Canada, 7Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden

    Background/Purpose: Previously published rheumatoid arthritis (RA) trials in which TNFi-MTX and triple therapy (MTX + hydroxychloroquine + sulfasalazine) were included as treatment arms in MTX…
  • Abstract Number: 1654 • 2015 ACR/ARHP Annual Meeting

    A Systematic Review and Network Meta-Analysis on the Efficacy of Tumor Necrosis Factor Inhibitor-Methotrexate Combination Therapy Versus Triple Therapy in Methotrexate-Naïve Patients with Rheumatoid Arthritis

    Roy Fleischmann1, Janet E. Pope2, Vanita Tongbram3, Derek Tang4, James Chung5, David Collier5, Shilpa Urs3, Kerigo Ndirangu3, George A. Wells6 and Ronald F. van Vollenhoven7, 1University of Texas Southwestern Medical Center, Dallas, TX, 2University of Western Ontario, London, ON, Canada, 3ICON Plc., Morristown, NJ, 4Amgen, Inc., Thousand Oaks, CA, 5Amgen Inc., Thousand Oaks, CA, 6Cardiovascular Research Reference Centre, University of Ottawa Heart Institute, Ottawa, ON, Canada, 7Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden

    Background/Purpose: Several published randomized head-to-head trials in rheumatoid arthritis (RA) have compared TNFi-MTX with triple therapy (MTX + hydroxychloroquine + sulfasalazine) in MTX-naive patients (MTX-Ns)…
  • Abstract Number: 2693 • 2015 ACR/ARHP Annual Meeting

    Comparing Eight Year Clinical and Radiographic Outcome in Two Cohorts of Patients with Rheumatoid Arthritis

    Maria LE Andersson1, Kristina Forslind2 and Ingiäld Hafström3, 1R&D Centre Spenshult,Halmstad, Halmstad, Sweden, 2Department of Medicine, Helsingborgs Lasarett, Section of Rheumatology, Helsingborg, Sweden, 3Rheumatology Dept, Karoliska Institute, Stockholm, Sweden

    Background/Purpose: To compare patient and disease characteristics over the first 8 years of disease in a large inception cohort of early RA patients included 1992…
  • Abstract Number: 2938 • 2015 ACR/ARHP Annual Meeting

    Baseline Predictors of Remission and Low Disease Activity Using Recently Defined International Criteria in a Multi-Center Lupus Registry Cohort

    Kichul Ko1, Alana B. Levine2, Russell Griffin3, Olga Dvorkina4, Saira Sheikh5, Jinoos Yazdany6, Richard Furie7 and Cynthia Aranow8, 1Section of Rheumatology and Gwen Knapp Center for Lupus and Immunology Research, University of Chicago, Chicago, IL, 2Rheumatology, Hospital for Special Surgery, New York, NY, 3University of Alabama at Birmingham, Birmingham, AL, 4Medicine, SUNY Health Science Center at Brooklyn, Brooklyn, NY, 5University of North Carolina, Chapel Hill, NC, 6Rheumatology, University of California, San Francisco, San Francisco, CA, 7Division of Rheumatology, North Shore - LIJ Health System, New York, NY, 8Feinstein Institute for Medical Research, Mahasset, NY

    Background/Purpose:  Treating to a target of remission or low disease activity state (LDAS) is an attractive potential therapeutic approach in SLE. Recently, LDAS and remission…
  • Abstract Number: 2904 • 2014 ACR/ARHP Annual Meeting

    Clinical and Radiological Features of Down’s Arthropathy

    Charlene Foley, Orla Killeen and Emma Jane MacDermott, The National Centre for Paediatric Rheumatology, Dublin, Ireland

    Background/Purpose The ‘Arthropathy of Down syndrome’ was first described in 1984. Three decades on we still have limited literature on the clinical & radiological features…
  • Abstract Number: 2404 • 2014 ACR/ARHP Annual Meeting

    RA Patients with Inadequate Response to Oral MTX Maintain Satisfactory Disease Control and Durable Long-Term Response When Switched to SC MTX Monotherapy

    Anthony Hammond1 and Michael Batley2, 1Rheumatology, Maidstone and Tunbridge Wells NHS Trust, Kent TN13 2JD, United Kingdom, 2Rheumatology, Maidstone and Tunbridge Wells Hospital, Kent, United Kingdom

    Background/Purpose: Methotrexate (MTX) is the cornerstone of rheumatoid arthritis (RA) therapy, but many patients do not achieve adequate response to oral therapy for reasons of…
  • Abstract Number: 1420 • 2014 ACR/ARHP Annual Meeting

    Non-Use of Glucocorticoid and Osteoarthritis Absence As Predictors of Clinical Remission in AR

    Salvador Loredo-Alanís1, David Vega-Morales2, Mario Garza-Elizondo1, Mario Garcia-Pompermayer3, Roberto Negrete-López1, Daniel Treviño-Montes1 and Diana Flores-Alvarado2, 1Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, Mexico, 2Rheumatology, Hospital Universitario UANL, Monterrey, Mexico, 3Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterey, Mexico

    Background/Purpose The clinical evaluation of Rheumatoid arthritis (RA) is accomplished with compound indexes allowing better clinical decision. Clinical remission nowadays is an attainable target in…
  • Abstract Number: 1318 • 2014 ACR/ARHP Annual Meeting

    Illness Onset Features and Misdiagnosis in Juvenile Idiopathic Inflammatory Myopathies (JIIM) Differ Among Clinical and Autoantibody (Ab) Subgroups

    Gulnara Mamyrova1, Lan Wu2, Adam Huber3, Ira N. Targoff4, Frederick W. Miller2 and Lisa G. Rider2, 1Rheumatology, George Washington University, Washington, DC, 2Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD, 3IWK Health Centre, Halifax, NS, Canada, 4Veterans Affairs Medical Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK

    Background/Purpose: To evaluate features of JIIM clinical and Ab subgroups at illness onset.  Methods: Physician-completed questionnaires illness onset features were reviewed in 465 JIIM pts…
  • Abstract Number: 1193 • 2014 ACR/ARHP Annual Meeting

    Diagnostic value of Contrast-Enhanced MR-Angiography in diagnosing large Vessel Vasculitis

    Sabine Adler1, Marco Sprecher1, Harald Bonel2, Thorsten Klink2 and Peter M. Villiger3, 1Rheumatology, Immunology, Allergology, University Hospital Bern, Bern, Switzerland, 2Diagnostic, Interventional and Pediatric Radiology, University Hospital Bern, Bern, Switzerland, 3Rheumatology, Immunology and Allergology, University Hospital Bern, Bern, Switzerland

    Background/Purpose Diagnosis of large-vessel vasculitis (LVV) remains difficult despite clinical and serological signs and symptoms. Detection by histology might be unavailable in exclusive thoracic or…
  • Abstract Number: 791 • 2014 ACR/ARHP Annual Meeting

    Comparison of Clinical Manifestations in Different Histological Subsets of Biopsy-Proven Giant Cell Arteritis

    Luigi Boiardi1, Francesco Muratore1, Alberto Cavazza2, Giovanna Restuccia3, Pierluigi Macchioni1, Giuseppe Germanò1, Nicolò Pipitone1, Gianluigi Bajocchi4 and Carlo Salvarani1, 1Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 2Pathology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 3Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 4Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Japan

    Background/Purpose: Temporal artery biopsy (TAB) showing transmural inflammation is considered the gold standard for the diagnosis of giant cell arteritis (GCA). In some cases of…
  • Abstract Number: 790 • 2014 ACR/ARHP Annual Meeting

    Correlations Between Histopathological Findings and Clinical Manifestations in a Large Monocentric Cohort of Patients with Biopsy-Proven Giant Cell Arteritis

    Luigi Boiardi1, Francesco Muratore1, Giovanna Restuccia2, Alberto Cavazza3, Pierluigi Macchioni1, Giuseppe Germanò1, Nicolò Pipitone1 and Carlo Salvarani1, 1Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 2Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 3Pathology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy

    Background/Purpose: Giant cell arteritis (GCA) is a vasculitis that involves large and medium sized arteries in patients older than 50 years. Temporal artery biopsy (TAB)…
  • Abstract Number: 789 • 2014 ACR/ARHP Annual Meeting

    Association Between Histological Features and Clinical Features of Patients with Biopsy Positive Giant Cell Arteritis

    Kimberley Ting1, Susan Lester2 and Catherine L. Hill3, 1Rheumatology, The Queen Elizabeth Hospital, Adelaide, Australia, 2Rheumatology Unit, Queen Elizabeth Hospital, Woodville South, Australia, 3Discipline of Medicine, University of Adelaide, Adelaide, Australia

    Background/Purpose: Temporal artery biopsy is the gold standard for diagnosing giant cell arteritis (GCA). The pathology of GCA characteristically involves transmural infiltrates, giant cell formation…
  • Abstract Number: 722 • 2014 ACR/ARHP Annual Meeting

    Prediction of Improvement in Skin Fibrosis in Diffuse Cutaneous Systemic Sclerosis

    Rucsandra Dobrota1,2, Britta Maurer1, Nicole Graf3, Carina Mihai2, Otylia Kowal-Bielecka4, Yannick Allanore5 and Oliver Distler on behalf of the EUSTAR investigators and co-authors1, 1Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 2Department of Internal Medicine and Rheumatology, Dr.I.Cantacuzino Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, 3graf biostatistics, Winterthur, Switzerland, 4Department of Rheumatology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland, 5Department of Rheumatology, University Paris Descartes and Cochin Hospital, Paris, France

    Background/Purpose Improvement of skin fibrosis over time is part of the “natural history” of patients with diffuse cutaneous systemic sclerosis (dcSSc). However, in the individual…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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