Abstracts tagged "Clinical"

Abstract Number: 191 • 2020 Pediatric Rheumatology Symposium
Utilization of Telemedicine in Pediatric Rheumatologic Care
Rajdeep Pooni¹ and Tzielan Lee ¹, ¹Stanford Children's, Palo Alto
Background/Purpose: Telemedicine has the potential for improving access to care, particularly for pediatric patients with complex needs in remote or rural locations. Previous studies have…
Abstract Number: 764 • 2019 ACR/ARP Annual Meeting
The Clinical and Angiographic Features of Chinese Takayasu’s Arteritis Patients: A Cohort Study of 591 Patients in 6 Years
Yunjiao Yang¹, Jing Li ², Xinping Tian ¹ and Xiaofeng Zeng ¹, ¹Peking Union Medical College Hospital, Beijing, China (People's Republic), ²Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Medical College, Beijing
Background/Purpose: To investigate the clinical and angiographic features of 591 Chinese Takayasu’s arteritis (TAK) patientsMethods: Clinical and angiographic findings of 591 Chinese TAK patients enrolled…
Abstract Number: 1320 • 2019 ACR/ARP Annual Meeting
Individual Socio-economic Status and Symptomatic Hip and Knee Osteoarthritis: A Longitudinal Study, Results from the KHOALA Cohort
Pauline Baudart¹, Anne-Christine Rat ², Christian Marcelli ¹ and Joséphine Bryère ³, ¹CHU Caen, rheumatology department, Caen Normandie University, Caen, France, ²CHU Caen, rheumatology department, Caen Normandie University, Université de Lorraine, EA 4360 APEMAC, Caen, France, ³Inserm, university of Caen research U1086 Anticipe, Caen, France
Background/Purpose: We analyzed the association between individual socio-economic status (SES) variables and clinical symptoms (function, pain and quality of life) in patients with symptomatic knee…
Abstract Number: 1338 • 2019 ACR/ARP Annual Meeting
Joint-specific Responses to Tofacitinib and Methotrexate in Rheumatoid Arthritis: A Post Hoc Analysis of Data from ORAL Start
Mojca Frank-Bertoncelj¹, Oliver Distler ², Tim Killeen ³, Kenneth Kwok ⁴, Lisy Wang ⁵, Caroline Ospelt ¹ and Adrian Ciurea ¹, ¹University Hospital Zürich, Zürich, Switzerland, ²Dept. of Rheumatology, University Hospital Zürich, Zürich, Switzerland, Zürich, Switzerland, ³Pfizer AG, Zürich, Switzerland, ⁴Pfizer Inc, New York, NY, ⁵Pfizer Inc, Groton, CT
Background/Purpose: Despite systemic inflammatory cues, RA affects synovial joints variably. Tofacitinib is an oral JAK inhibitor for the treatment of RA. Previous post hoc analyses…
Abstract Number: 1348 • 2019 ACR/ARP Annual Meeting
Impact of Tofacitinib on the Individual Components of the ACR Composite Score in Patients with Rheumatoid Arthritis: A Post Hoc Analysis of Phase 3 Trials
Louis Bessette¹, Maxime Dougados ², Eduardo Mysler ³, Mark Genovese ⁴, Cassandra Kinch ⁵, Kenneth Kwok ⁶, Tatjana Lukic ⁶, Tanya Girard ⁵, Pierre-Alexandre Landry ⁵ and Ronald van Vollenhoven ⁷, ¹Laval University, Quebec City, QC, Canada, ²Cochin Hospital, Paris, France, ³Organización Médica de Investigación, Buenos Aires, Argentina, ⁴Stanford University, Stanford, CA, ⁵Pfizer Canada ULC, Kirkland, QC, Canada, ⁶Pfizer Inc, New York, NY, ⁷Amsterdam Rheumatology and Immunology Center, Amsterdam, Netherlands
Background/Purpose: Tofacitinib is an oral JAK inhibitor for the treatment of RA. In clinical trials, standard criteria for measuring treatment efficacy in patients (pts) with…
Abstract Number: 2536 • 2018 ACR/ARHP Annual Meeting
Vagus Nerve Stimulation in Patients with Rheumatoid Arthritis: 24 Month Safety and Efficacy
Frieda A. Koopman¹, Anne Musters², Marieke M.J. Backer², Danielle Gerlag², Sanda Miljko³, Simeon Grazio⁴, Sekib Sokolovic⁵, Yaakov Levine⁶, David Chernoff⁶, Niek de Vries⁷ and Paul-Peter Tak², ¹Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ²Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ³University Clinical Hospital, Mostar, Bosnia, ⁴Vinogradsira 29, Clinical Hospital Center Sestre Milosrdnice, Zagreb, Croatia, ⁵Rheumatology, Sarajevo University Clinical Center, Sarajevo, BA, ⁶SetPoint Medical, Inc., Valencia, CA, ⁷Dept. of Experimental Immunology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands
Background/Purpose: RA is a debilitating chronic disease with an unmet need for additional therapeutic approaches. Modulating innate neuro-immune reflex pathways by stimulation of the vagus…
Abstract Number: 2663 • 2018 ACR/ARHP Annual Meeting
Comparison of Clinical and Laboratory Profiles in 3575 Systemic Lupus Erythematosus Patients with and without Sjögren’s Syndrome: Data from the Spanish Society for Rheumatology Lupus Registry
Juan Gabriel Ovalles-Bonilla^1,2, Francisco Javier López Longo³, Iñigo Rúa-Figueroa⁴, María Galindo⁵, Jaime Calvo-Alén⁶, Juan Carlos Nieto², Julia Martínez-Barrio³, Roberto González⁷, Belen Serrano⁸, Iustina Janta², Carlos M Gonzalez⁹, Indalecio Monteagudo² and JM Pego-Reigosa¹⁰, ¹Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain, ²Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain, ³Rheumatology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain, ⁴Rheumatology Division, Hospital Doctor Negrin, Las Palmas GC, Spain, ⁵Servicio de Reumatología, Hospital 12 de Octubre, Madrid, Spain, ⁶Rheumatology Department, Hospital Universitario Araba. Vitoria-Gasteiz, Alava, Spain, ⁷Rheumatology, Hospital general Universitario Gregorio Marañón, Madrid, Spain, ⁸Rheumatology, Hospital General Universitario Gregorio Marañón, Genoa, Italy, ⁹Servicio de Reumatología, Hospital General Universitario Gregorio Marañón, Madrid, Spain, ¹⁰Complexo Hospitalario Universitario de Vigo, Vigo, Spain
Background/Purpose: The clinical coexistence of Systemic Lupus Erythematosus (SLE) and Sjögren's Syndrome (SS) was recognized in 1959. The prevalence of SS among patients with SLE…
Abstract Number: 2881 • 2018 ACR/ARHP Annual Meeting
How Immunological Profile Drives Clinical Phenotype of Primary Sjögren’s Syndrome at Diagnosis: Analysis of 10.500 Patients (Sjögren Big Data Project)
Soledad Retamozo^1,2, Nihan Acar-Denizli³, Wan-Fai Ng⁴, Margit Zeher⁵, Astrid Rasmussen⁶, Thomas Mandl⁷, Raphaele Seror⁸, Xiaomei Li⁹, Chiara Baldini¹⁰, Jacques-Eric Gottenberg¹¹, Debashish Danda¹², Luca Quartuccio¹³, Roberta Priori¹⁴, Gabriela Hernandez-Molina¹⁵, Berkan Armagan¹⁶, Aike A. Kruize¹⁷, Seung-Ki Kwok¹⁸, Marika Kvarnström¹⁹, Sonja Praprotnik²⁰, Damien Sène²¹, Elena Bartoloni²², Roser Solans²³, Maureen Rischmueller²⁴, Yasunori Suzuki²⁵, David A. Isenberg²⁶, Valeria Valim²⁷, Piotr Wiland²⁸, Gunnel Nordmark²⁹, Guadalupe Fraile³⁰, Hendrika Bootsma³¹, Takashi Nakamura³², Roberto Giacomelli³³, Valérie Devauchelle-Pensec³⁴, Andreas Knopf³⁵, Michele Bombardieri³⁶, Virginia Fernandes Trevisani³⁷, Daniel S. Hammenfors³⁸, Sandra G Pasoto³⁹, Tamer A. Gheita⁴⁰, Fabiola Atzeni⁴¹, Jacques Morel⁴², Cristina Vollenveider⁴³, Ildiko-Fanny Horvath⁵, Kathy L. Sivils⁴⁴, Peter Olsson⁴⁵, Salvatore De Vita⁴⁶, Jorge Sánchez-Guerrero⁴⁷, Levent Kilic¹⁶, Marie Wahren-Herlenius⁴⁸, Xavier Mariette⁸, Manuel Ramos-Casals⁴⁹ and Pilar Brito-Zerón^50,51, ¹Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Córdoba, Consejo Nacional de Investigaciones Científicas y Técnicas (INICSA-UNC-CONICET), Cordoba, Argentina, ²Rheumatology Unit, Hospital Privado Universitario de Córdoba, Institute University of Biomedical Sciences University of Córdoba (IUCBC), Cordoba, Argentina, ³Department of Statistics, Faculty of Science and Letters, Mimar Sinan Fine Arts University, Istanbul, Turkey, Istanbul, Turkey, ⁴Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, Newcastle, United Kingdom, ⁵Division of Clinical Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary, ⁶Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, USA, Oklahoma City, OK, ⁷Department of Rheumatology, Skåne University Hospital, Malmö, Sweden, Lund, Sweden, ⁸Rheumatology department, Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique- Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM, Paris, Paris, France, ⁹Department of Rheumatology and Immunology, Anhui Provincial Hospital, Hefei., Hefei, China, ¹⁰Rheumatology Unit, University of Pisa, Pisa, Italy, ¹¹Rhumatologie, Hôpitaux universitaires de Strasbourg, Strasbourg, France, ¹²Clinical Immunology & Rheumatology, Christian Medical College, Vellore, India, Vellore, India, ¹³Clinic of Rheumatology, Department of Medical Area (DAME), University Hospital “Santa Maria della Misericordia”, Udine., Udine, Italy, ¹⁴Department of Internal Medicine and Medical Specialties, Rheumatology Clinic, Sapienza University of Rome., Rome, Italy, ¹⁵Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico City, Mexico, ¹⁶Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, ¹⁷Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, ¹⁸Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul., Seoul, Korea, Republic of (South), ¹⁹Unit of Rheumatology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, Stockholm, Sweden, ²⁰Department of Rheumatology, University Medical Centre, Ljubljana., Ljubljana, Slovenia, ²¹Lariboisière Hospital, Paris Diderot University, Paris, France, ²²Rheumatology Unit, University of Perugia, Perugia, Italy, ²³Department of Internal Medicine, Hospital Vall d’Hebron, Barcelona, Barcelona, Spain, ²⁴The Queen Elizabeth Hospital and University of Adelaide, Adelaide, Australia, ²⁵Ishikawa, Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Ishikawa, Ishikawa, Japan, ²⁶Centre for Rheumatology Research, University College Hospital London, UK, London, United Kingdom, ²⁷Department of Medicine, Federal University of Espírito Santo and University Hospital HUCAM/EBSERH, Vitória, Vitoria, Brazil, ²⁸Department of Rheumatology and Internal Medicine, Wroclaw Medical Hospital, Wroclaw, Wroclaw, Poland, ²⁹Rheumatology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden, ³⁰Department of Internal Medicine, Hospital Ramón y Cajal, Madrid, Madrid, Spain, ³¹Department of Rheumatology & Clinical Immunology, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands, ³²Department of Radiology and Cancer Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ³³Clinical Unit of Rheumatology, University of l’Aquila, School of Medicine, L’Aquila, L’Aquila, Italy, ³⁴Rheumatology Department, Brest University Hospital, Brest, Brest, France, ³⁵Otorhinolaryngology/ Head and Neck Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany, ³⁶Centre for Experimental Medicine and Rheumatology, Queen Mary University of London, London, United Kingdom, ³⁷Federal University of São Paulo, São Paulo, Brazil, ³⁸Department of Rheumatology, Haukeland University Hospital, University of Bergen, Bergen, Norway, ³⁹Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, ⁴⁰Rheumatology Department, Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt, ⁴¹IRCCS Galeazzi Orthopaedic Institute, Milan, and Rheumatology Unit, University of Messina, Messina, Italy, ⁴²Department of Rheumatology, Montpellier University Hospital and University of Montpellier, Montpellier, France, ⁴³German Hospital, Buenos Aires, Buenos Aires, Argentina, ⁴⁴Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma, OK, ⁴⁵Department of Rheumatology, Skane University Hospital Malmö, Lund University, Malmö, Malmö, Sweden, ⁴⁶Clinic of Rheumatology, Department of Medical Area (DAME), University Hospital “Santa Maria della Misericordia”, Udine, Udine, Italy, ⁴⁷Immunology and Rheumatology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, Mexico, Mexico, ⁴⁸Department of Medicine, Solna, Unit of Experimental Rheumatology, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden, Stockholm, Sweden, ⁴⁹University of Barcelona, Hospital Clínic, Barcelona, Barcelona, Spain, ⁵⁰Sjögren’s Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX, Department of Autoimmune Diseases, ICMiD, University of Barcelona, Hospital Clínic, Barcelona, Bercelona, Spain, ⁵¹Autoimmune Diseases Unit, Department of Medicine, Hospital CIMA Sanitas, Barcelona, Barcelona, Spain
Background/Purpose: To evaluate the influence of the main immunological markers on the disease phenotype at diagnosis in a large international cohort of patients with primary…
Abstract Number: 316 • 2018 ACR/ARHP Annual Meeting
Eligibility Rates in Axial Spondyloarthritis Clinical Trials Based on Imaging Criteria
Farhan A. Syed¹, David Bennett¹, Michael O'Connor¹, Gabriele Pradella² and Sarah Warner¹, ¹Scientific and Medical Services, PAREXEL International, Billerica, MA, ²Image Management, PAREXEL International, Billerica, MA
Background/Purpose: Axial Spondyloarthritis (AxSpA) encompasses both non-radiographic (nr-AxSpA) as well as radiographic ankylosing spondylitis (AS) which displays structural changes at the sacro-iliac joint (SIJ). Phase…
Abstract Number: 1369 • 2018 ACR/ARHP Annual Meeting
The Influence of Hand Osteoarthritis on Bone Microstructure and Biomechanical Properties of Radial Bone
David Simon, Sara Unbehend, Sara Bayat, Juergen Rech, Axel J. Hueber, Georg Schett and Arnd Kleyer, Department of Internal Medicine 3—Rheumatology and Immunology, Friedrich-Alexander-University Erlangen–Nürnberg (FAU), Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, Germany
Background/Purpose: Primary hand osteoarthritis (HOA) is a heterogeneous disease, with erosive and osteoproliferative changes of the finger joints. [1] Due to the lack of treatment…
Abstract Number: 1775 • 2018 ACR/ARHP Annual Meeting
IgG4-Related Disease, Clinical Series on Chilean Patients
Carolina Cuéllar¹, Oscar Neira^2,3, Alejandra Herrera⁴, Miguel Gutérrez⁵, Fabián Elgueta⁶, Pamela Wurmann⁶, Bellanides Mansilla^4,7, Javier Basualdo^2,8, Jorge Vega⁵, Daniel Erlij², Cristián Labarca³, Cristián Vergara⁵, Verónica Mezzano^9,10, Paula Pastenes¹¹, Lilith Stange¹², Susana Michalland², Francisco Silva³, Aquiles Jara¹³, I. Annelise Goecke⁶, Carolina Llanos⁹, María Badilla², Rodrigo Tagle¹³, Paula Burgos⁹, Mirentxu Iruretagoyena⁹, Patricio Sandoval¹⁴, Cristina Fernández¹⁵ and Carolina Landeros¹⁶, ¹Rheumatology Section., Hospital del Salvador, Universidad de Chile., SANTIAGO, Chile, ²Rheumatology Section., Hospital del Salvador, Universidad de Chile., Santiago, Chile, ³Rheumatology Unit, Clinica Alemana de Santiago. Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile, ⁴Rheumatology Departament, Pontificia Universidad Católica de Chile., Santiago, Chile, ⁵Hospital Naval Almirante Nef, Viña del Mar., Viña del Mar, Chile, ⁶Rheumatology Section, Hospital Clínico Universidad de Chile, Santiago, Chile, ⁷Hospital Clínico Magallanes, Punta Arenas, Chile, ⁸Clínica Santa María de Santiago., Santiago, Chile, ⁹Rheumatology Departament., Pontificia Universidad Católica de Chile., Santiago, Chile, ¹⁰Clínica Las Condes., Santiago, Chile, ¹¹Hospital Carlos Van Buren, Valparaíso, Chile, ¹²Clínica Ciudad del Mar, Viña del Mar, Chile, ¹³Nephrology Departament., Pontificia Universidad Católica de Chile., Santiago, Chile, ¹⁴Neurology Departament., Pontificia Universidad Católica de Chile., Santiago, Chile, ¹⁵Instituto Nacional del Tórax., Santiago, Chile, ¹⁶Internal Medicine Service., Hospital del Salvador, Universidad de Chile., Santiago, Chile
Background/Purpose: IgG4-related disease (IgG4-RD) is a chronic fibroinflammatory condition that can affect almost any organ. Gold standard for diagnosis, biopsy, can shows lymphoplasmacytic infiltration, storiform…
Abstract Number: 247 • 2017 ACR/ARHP Annual Meeting
Near Infrared Indocyanine Green Imaging Reveals Diminished Flow in Basilic Associated Lymphatic Vessels in the Hands of Rheumatoid Arthritis Patients during Flare
Richard Bell¹, Alicia Lieberman², Ronald Wood³, Cristy Bell⁴, Homaira Rahimi⁵, Edward Schwarz⁶ and Christopher T. Ritchlin⁷, ¹Orthopedics, University of Rochaester, Rochester, NY, ²Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ³University of Rochester, Rochester, NY, ⁴Allergy, Immunology & Rheumatology, University of Rochester, Rochester, NY, ⁵Rheumatology, University of Rochester/Golisano Children's Hosp, Rochester, NY, ⁶Orthopedeatrics, University of Rochester, Rochester, NY, ⁷Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY
Background/Purpose: Near infrared (NIR) imaging studies of subdermal indocyanine green (ICG) in murine models of inflammatory arthritis established the important contribution of lymphatic vessel (LV)…
Abstract Number: 306 • 2017 ACR/ARHP Annual Meeting
Relationship between Inflammatory Anterior or Posterior Arch MRI Abnormalities and Clinical Data in Low Back Pain Patients
Helene Braun¹, Clement Geniez¹, Yannick Degboe², Arnaud Constantin³, Alain Cantagrel⁴, Delphine Nigon⁵, Marie Faruch-Bilfeld¹ and Adeline Ruyssen-Witrand⁴, ¹Purpan Hospital, Toulouse, France, ²Department of Rheumatology, Purpan Hospital, Toulouse III University, Toulouse, France, Toulouse, France, ³Purpan Hospital, toulouse, France, ⁴Rheumatology, Purpan Hospital, Toulouse III University, Toulouse, France, ⁵CHU Purpan, Toulouse, France
Background/Purpose: To compare demographic characteristics, characteristics of pain and functional status according to the presence of inflammatory anterior or posterior arch MRI abnormalities in low…
Abstract Number: 934 • 2017 ACR/ARHP Annual Meeting
Effectiveness of FX006 Intra-Articular Injection in Patients with Knee Osteoarthritis Who Present with and without Clinical Inflammation at Baseline: A Pooled Analysis of Data from 3 Double-Blind, Randomized, Parallel-Group Clinical Trials
Herbert S. B. Baraf¹, Christian Lattermann², Deryk G. Jones³, Philip G. Conaghan⁴, Joelle Lufkin⁵, James Johnson⁶, Scott Kelley⁵ and Neil Bodick⁵, ¹Center for Rheumatology and Bone Research, Wheaton, MD, ²University of Kentucky, Orthopaedic Surgery and Sports Medicine, Lexington, KY, ³Ochsner Sports Medicine Institute, New Orleans, LA, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵Flexion Therapeutics, Inc., Burlington, MA, ⁶Summit Analytical, Denver, CO
Background/Purpose: Inflammation is a key contributor to osteoarthritis (OA).1 OA pain is mediated by interactions between inflammatory cytokines and other features including local tissue damage,…
Abstract Number: 1200 • 2017 ACR/ARHP Annual Meeting
Updating the Knee Osteoarthritis Intra-Articular Corticosteroid Meta-Analysis with Two Large Trials of Extended-Release Triamcinolone Acetonide (FX006) Versus Placebo
Philip G. Conaghan¹, Francis Berenbaum², Virginia B. Kraus³, James Johnson⁴ and Scott Kelley⁵, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²Pierre & Marie Curie University, Saint-Antoine Hospital, Paris, France, ³Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, ⁴Summit Analytical, Denver, CO, ⁵Flexion Therapeutics, Inc., Burlington, MA
Background/Purpose: A recent meta-analysis concluded that intra-articular corticosteroids (IACS) for knee osteoarthritis (OA) may be associated with moderate improvement in pain compared with control treatment.1,2…

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