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Abstracts tagged "classification criteria"

  • Abstract Number: 0903 • ACR Convergence 2021

    Scoring MRI Structural Lesions in Sacroiliac Joints of Patients with Axial Spondyloarthritis: How Many Slices Are Optimal?

    Walter Maksymowych1, Ulrich Weber2, Xenofon Baraliakos3, Pedro Machado4, Susanne Pedersen5, Joachim Sieper6, Stephanie Wichuk7, Denis Poddubnyy8, Martin Rudwaleit9, Désirée van der Heijde10, Robert Landewé11, Joel Paschke12, Mikkel Ostergaard13 and Robert Lambert7, 1Department of Medicine, University of Alberta, Alberta, Canada, Edmonton, AB, Canada, 2Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, 3Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, 4Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, 5Rigshospitalet, Center for Arthritis Research, Glostrup, Denmark, 6Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, 7University of Alberta, Edmonton, AB, Canada, 8Department of Rheumatology, Charité – Universitätsmedizin, Berlin, Germany, 9University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany, 10Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, 11Amsterdam Rheumatology & Clinical Immunology Center, Amsterdam, Netherlands; Zuyderland MC, Heerlen, Netherlands, 12CARE Arthritis, Edmonton, AB, Canada, 13Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, and Department of Clinical Medicine, University of Copenhagen, Glostrup, Denmark

    Background/Purpose: There is no international consensus on the optimal number of slices for evaluation of MRI structural lesions in the SIJ. An “all slice” method…
  • Abstract Number: 0904 • ACR Convergence 2021

    Data-driven Definitions Based on Inflammatory Lesions for a Positive MRI of the Spine Consistent with Axial Spondyloarthritis

    Walter Maksymowych1, Robert Lambert2, Xenofon Baraliakos3, Susanne Pedersen4, Iris Eshed5, Ulrich Weber6, Pedro Machado7, Manouk de Hooge8, Joachim Sieper9, Stephanie Wichuk2, Denis Poddubnyy10, Martin Rudwaleit11, Robert Landewé12, Désirée van der Heijde13 and Mikkel Ostergaard14, 1Department of Medicine, University of Alberta, Alberta, Canada, Edmonton, AB, Canada, 2University of Alberta, Edmonton, AB, Canada, 3Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, 4Rigshospitalet, Center for Arthritis Research, Glostrup, Denmark, 5Sheba Medical Center, Ramat Gan, Israel, 6Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, 7Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, 8Ghent University Hospital, Ghent, Belgium, 9Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, 10Department of Rheumatology, Charité – Universitätsmedizin, Berlin, Germany, 11University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany, 12Amsterdam Rheumatology & Clinical Immunology Center, Amsterdam, Netherlands; Zuyderland MC, Heerlen, Netherlands, 13Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, 14Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, and Department of Clinical Medicine, University of Copenhagen, Glostrup, Denmark

    Background/Purpose: The ASAS definition of a positive MRI for inflammation in the spine (ASAS-MRI+) is intended for classification of patients as having axSpA but is…
  • Abstract Number: 0975 • ACR Convergence 2021

    Data-driven MRI Definitions for Active and Structural Sacroiliac Joint Lesions in Juvenile Spondyloarthritis Typical of Axial Disease

    Pamela Weiss1, Timothy Brandon1, Amita Aggarwal2, Ruben Burgos-Vargas3, Robert Colbert4, Gerd Horneff5, Rik Joos6, Ronald Laxer7, Kirsten Minden8, Angelo Ravelli9, Nicolino Ruperto10, Judith Smith11, Matthew Stoll12, Shirley Tse7, Filip Van den Bosch13, Robert Lambert14, David Biko15, Nancy Chauvin16, Michael Francavilla15, Jacob Jaremko14, Nele Herregods17, Ozgur Kasapcopur18, Mehmet YILDIZ19, Alison Hendry20 and Walter Maksymowych21, 1Children's Hospital of Philadelphia, Philadelphia, PA, 2Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, 3Department of Rheumatology, General Hospital of Mexico, Ciudad de Mxico, Mexico, 4NIH/NIAMS, Bethesda, MD, 5Paediatric Rheumatology International Trials Organisation (PRINTO), Sankt Augustin, Germany, 6Ghent University, Ghent, Belgium, 7SickKids, Toronto, ON, Canada, 8German Rheumatism Research Center, Berlin, Germany, 9Istituto Giannina Gaslini, Genoa, Italy, 10IRCCS Istituto Giannina Gaslini; PRINTO, Clinica Pediatrica e Reumatologia, Genova, Italy, 11University of Wisconsin, Madison, WI, 12University of Alabama at Birmingham, Birmingham, AL, 13Dept. of Rheumatology - Ghent University Hospital, Ghent, Belgium, Ghent, Belgium, 14University of Alberta, Edmonton, AB, Canada, 15University of Pennsylvania, Philadelphia, PA, 16Penn State Health, Hershey, PA, 17Universitair Ziekenhuis Ghent, Ghent, Belgium, 18Istanbul University-Cerrahpasa, Cerrahpasa Medical School, İstanbul, Turkey, 19Istanbul University-Cerrahpasa, Faculty of Medicine, Pediatric Rheumatology, İstanbul, Turkey, 20NZ Familial GI Cancer Service, Auckland, New Zealand, 21Department of Medicine, University of Alberta, Alberta, Canada, Edmonton, AB, Canada

    Background/Purpose: Determining optimal cut-offs for active and structural imaging lesions of juvenile spondyloarthritis (JSpA) with axial disease is important for diagnosis, therapeutic management, and classification.…
  • Abstract Number: 1609 • ACR Convergence 2020

    The Accuracy of Administrative Health Data for Identifying Patients with Rheumatoid Arthritis: A Validation Study Using Medical Records in Western Australia

    Khalid Almutairi1, Johannes Nossent1, David Preen1, Helen Keen1, Katrina Rogers2 and Charles Inderjeeth1, 1The University of Western Australia, Perth, Western Australia, Australia, 2Sir Charles Gairdner Hospital, Perth, Western Australia, Australia

    Background/Purpose: The use of large administrative health datasets is increasingly important in Rheumatology for disease trends and outcome research. We established the West Australian Rheumatic…
  • Abstract Number: 1863 • ACR Convergence 2020

    Clinical History as Tool for Diagnosis and Classification of Patients with Ankylosing Spondylitis (Axial Spondyloarthritis): Evidence from a 35-Year Follow-up Family Study of a Swiss Cohort

    Sjef van der Linden1, Zhixiu Li2, Matthew Brown3, Peter Villiger4, Heinz Baumberger5, Hermine Zandwijk6 and Muhammad Khan7, 1Department of Rheumatology, Immunology and Allergology, University of Bern, Inselspital, Bern, Switzerland, Mortroux, Belgium, 2Queensland University of Technology (QUT), Translational Genomics Group, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Translational Research Institute, Princess Alexandra Hospital, Brisbane, Qld, Australia, Brisbane, Queensland, Australia, 3Guy's and St Thomas, NHS Foundation Trust and King's College London NIHR Biomedical Research Centre, King's College London, London, United Kingdom, London, United Kingdom, 4Department of Rheumatology, Immunology and Allergology, University of Bern, Inselspital, Switzerland, Bern, Switzerland, 5Retired, Flims, Tajikistan, 6Retired, Mortroux, Belgium, 7Case Western Reserve University, Cleveland OH, Westlake, OH

    Background/Purpose: Lack of sensitivity or specificity of symptoms may induce uncertainty in diagnosis and classification of AS/axSpA. We investigated if balanced sensitivity and specificity of…
  • Abstract Number: 0092 • ACR Convergence 2020

    Diagnosis of Behçet’s Disease: Comparison of Two Sets of Classification Criteria. Application in 111 Patients of a Well-defined Population

    David Martinez-Lopez1, Alba Herrero Morant2, Carmen Alvarez-Reguera2, Lara Sanchez-Bilbao2, Inigo Gonzalez-Mazon3, José Luis Martín-Varillas4, Guillermo Suarez-Amorin2, Patricia Setien-Preciados2, Cristina Mata-Arnaiz5, Miguel Ángel González-Gay6 and Ricardo Blanco2, 1Hospital Universitario Marques de Valdecilla, Santander (SPAIN), Spain, 2Hospital Universitario Marques de Valdecilla, Santander, Spain, 3Hospital Universitario Marques de Valdecilla, Bezana, Spain, 4Hospital Sierrallana, Torrelavega, Spain, 5Hospital de Laredo, Santander, Spain, 6Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain

    Background/Purpose: Behçet’s disease (BD) is a systemic, chronic, relapsing vasculitis with no pathognomonic diagnostic test. The most widely used classification criteria are those of the…
  • Abstract Number: 1870 • ACR Convergence 2020

    Development of Candidate Criteria for Axial Disease in Juvenile Spondyloarthritis: An International Collaboration

    Pamela F. Weiss1, Timothy G. Brandon2, Amita Aggarwal3, Ruben Burgos-Vargas4, Robert Colbert5, Gerd Horneff6, Rik Joos7, Ronald Laxer8, Kirsten Minden9, Angelo Ravelli10, Nicolino Ruperto11, Judith Smith12, Matthew Stoll13, Shirley Tse14, Filip Van den Bosch15 and Raymond Naden16, 1Children's Hospital of Philadelphia, Philadelphia, 2Children's Hospital of Philadelphia, Philadelphia, PA, 3Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, 4Department of Rheumatology, General Hospital of Mexico, Ciudad de Mexico, Mexico, 5Pediatric Clinical Trials Unit and Office of Clinical Director, NIAMS, NIH, Bethesda, MD, 6Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, 7Ziekenhuis Netwerk Antwerpen, Basel, Switzerland, 8The Hospital for Sick Children, Toronto, ON, Canada, 9Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany, 10Università degli Studi di Genova, Genoa, Italy, 11PRINTO, Istituto Giannina Gaslini, Genova, Italy, 12University of Wisconsin, Madison, WI, 13University of Alabama at Birmingham, Birmingham, AL, 14SickKids, Toronto, ON, Canada, 15Ghent University Hospital, Ghent, Belgium, 16Department of Medicine, Middlemore Hospital, Auckland, Auckland, New Zealand

    Background/Purpose: The lack of pediatric classification criteria for axial disease is a major impediment to the conduct of clinical trials for juvenile spondyloarthritis (SpA). Classification…
  • Abstract Number: 0270 • ACR Convergence 2020

    The New EULAR/ ACR 2019 SLE Classification Criteria: Defining Ominosity in SLE

    Laura Whittall-Garcia1, Dafna Gladman2, Murray Urowitz3, Jiandong Su4 and Sindhu Johnson5, 1University Health Network, Toronto, ON, Canada, 2Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, 3University Health Network, University of Toronto, Toronto, ON, Canada, 4University of Toronto Lupus Clinic, Centre for Prognosis Studies in Rheumatic Diseases, Toronto Western Hospital, University Health Network, Toronto, ON, Canada, 5University of Toronto, Toronto, ON, Canada

    Background/Purpose: SLE is characterized by different patterns of disease activity throughout its course. Overall, a higher disease activity is an important predictor of mortality and…
  • Abstract Number: 2038 • ACR Convergence 2020

    Characterizing Morphea Subsets Using a Multi-center, Prospective, Cross-sectional Analysis

    Jane Zhu1, Smriti Prasad2, Kaila Schollaert-Fitch3, Robert Haley4, Kathryn Torok3 and Heidi Jacobe2, 1UT Southwestern Medical Center, Dallas, 2University of Texas Southwestern Medical Center, Dallas, TX, 3University of Pittsburgh, Pittsburgh, PA, 4University of Texas Southwestern Medical Center, Dallas

    Background/Purpose: Morphea, or localized scleroderma, is an inflammatory condition of the skin and soft tissue that results in excessive collagen deposition, often producing permanent functional…
  • Abstract Number: 0277 • ACR Convergence 2020

    Incidence and Time to Classification of Systemic Lupus Erythematosus by Three Different Classification Criteria

    Ali Duarte-Garcia1, Mehmet Hocaoglu2, Shirley-Ann Osei-Onomah3, Jesse Dabit1, Rachel Giblon1 and Cynthia Crowson4, 1Mayo Clinic, Rochester, MN, 2University of Maryland Medical Center Midtown Campus, Baltimore, MD, 3Mayo Clinic, Rochester, 4Mayo Clinic, Rochester, Minnesota, USA, Rochester, MN

    Background/Purpose: Classification criteria are standardized definitions required to identify well defined cohorts of patients for research. In practice they are also used as a framework…
  • Abstract Number: 0301 • ACR Convergence 2020

    Genetic Associations and Polygenic Risk Assessment in Incomplete Lupus Erythematosus

    Matthew Slief1, Jeremy Levin2, Susan Macwana1, Wade DeJager1, Rebecka Bourn3, Swapan Nath3, Melissa Munroe4, Teresa Aberle1, Patrick Gaffney5, Joan Merrill3, Judith James6 and Joel Guthridge1, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2OU Medical Center, Oklahoma City, 3Oklahoma Medical Research Foundation, Oklahoma City, 4Oklahoma Medical Research Foundation/Progentec Diagnostics, Inc., Oklahoma City, OK, 5Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 6Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation;Department of Pathology, University of Oklahoma Health Sciences Center;Department of Medicine, University of Oklahoma Health Sciences Center, Edmond, OK

    Background/Purpose: Patients with incomplete lupus erythematosus (ILE) have features of lupus, but have insufficient criteria for SLE classification. Some ILE patients transition to classified SLE,…
  • Abstract Number: 0303 • ACR Convergence 2020

    SLE Patients Stratify into Distinct Clusters Based on Their Peripheral Blood Immunologic Phenotype During Acute Flare

    Kieran Manion1, Carolina Munoz-Grajales2, Michael Kim3, Kirubel Goliad4, Dennisse Bonilla5, Dafna Gladman1, Murray Urowitz6, Zahi Touma7 and Joan Wither5, 1Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, 2University of Toronto-UHN, Toronto, ON, Canada, 3Krembil Research Insitute, Toronto, ON, Canada, 4University of Toronto-UHN, Toronto, Canada, 5University of Toronto Lupus Clinic, Centre for Prognosis Studies in Rheumatic Diseases, Toronto Western Hospital, University Health Network, Toronto, ON, Canada, 6University Health Network, University of Toronto, Toronto, ON, Canada, 7University of Toronto, Toronto, ON, Canada

    Background/Purpose: SLE is a chronic autoimmune disease in which periods of quiescence are interspersed with acute flares of disease activity that produce much of the…
  • Abstract Number: 0401 • ACR Convergence 2020

    Prevalence and Characteristics of Systemic Sclerosis Patients Fulfilling the 2019 EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus

    Ronald Bass1, Duncan Moore2 and Virginia Steen2, 1Georgetown University School of Medicine, Washington, DC, 2Division of Rheumatology, Department of Medicine, MedStar Georgetown University Hospital, Washington, DC

    Background/Purpose: Literature describing the overlap syndrome of SSc and SLE is limited and has employed a range of case definitions. Our study sought to use…
  • Abstract Number: 0521 • ACR Convergence 2020

    Avoiding Misclassification of Primary Antiphospholipid Syndrome as Systemic Lupus Erythematosus: What Are the Best-performing SLE Classification Criteria?

    Flavio Signorelli1, Gustavo Balbi2, Eloisa Bonfa3, Eduardo Borba4 and Danieli Andrade5, 1Universidade de São Paulo, Rio de janeiro, Rio de Janeiro, Brazil, 2Universidade de São Paulo, Juiz de Fora, Minas Gerais, Brazil, 3Hospital das Clínicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Sao Paulo, Brazil, 4Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, 5University of Sao Paulo, Sao Paulo, Brazil

    Background/Purpose: Primary Antiphospholipid Syndrome (PAPS) patients, when submitted to Systemic Lupus Erythematosus (SLE) classification criteria, can be misclassified. The new 2019 ACR/EULAR classification criteria have…
  • Abstract Number: 0522 • ACR Convergence 2020

    Development of New International Classification Criteria for Antiphospholipid Syndrome: Phase III Case Collection Results

    Medha Barbhaiya1, Stephane Zuily2, Yasaman Ahmadzadeh3, Karen Costenbader4, Raymond Naden5 and Doruk Erkan6, 1Hospital for Special Surgery, Barbara Volcker Center for Women and Rheumatic Diseases, New York, NY, 2Nancy Academic Hospital, Vandoeuvre-l�Nancy, France, 3Hospital for Special Surgery, New York, 4Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 5Department of Medicine, Middlemore Hospital, Auckland, Auckland, New Zealand, 6Hospital for Special Surgery, New York, NY

    Background/Purpose: An international multi-disciplinary effort is underway to develop rigorous, new, consensus- and evidence-based classification criteria for Antiphospholipid Syndrome (APS). The methodological approach includes four…
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