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Abstracts tagged "classification criteria"

  • Abstract Number: 1733 • ACR Convergence 2021

    Classification of Patients with Systemic Lupus Erythematosus Enrolled in 2 Phase 3 Trials by EULAR/ACR 2019 Criteria

    Martin Aringer1, Ian N. Bruce2, Richard Furie3, Eric Morand4, Emmanuelle Maho5, Catharina Lindholm6 and Raj Tummala7, 1University Medical Center and Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany, 2University of Manchester and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom, 3Zucker School of Medicine at Hofstra/Northwell Health, Great Neck, NY, 4Monash University, Melbourne, Australia, 5BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom, 6BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden, 7BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD

    Background/Purpose: The TULIP-1 and TULIP-2 trials of anifrolumab, an anti–type I IFN receptor mAb, enrolled autoantibody-positive (ANA, anti-dsDNA, and/or anti-Smith [anti-Sm]) patients, who fulfilled the…
  • Abstract Number: 0335 • ACR Convergence 2021

    Performances of Different Classification Criteria for Systemic Lupus Erythematosus in a Single Center Cohort from Turkey

    Ege Sinan Torun1, Erdem Bektaş1, Fatih Kemik2, Murat Bektaş3, Cigdem Cetin4, Yasemin Yalcinkaya4, Bahar Esen4, Ahmet Gül5 and Murat Inanc6, 1Istanbul University Istanbul Faculty of Medicine, İstanbul, Turkey, 2Istanbul Faculty of Medicine, Istanbul University, Department of Internal Medicine, İstanbul, Turkey, 3Istanbul Faculty of Medicine, Istanbul, Turkey, 4Division of Rheumatology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey, 5Division of Rheumatology, Istanbul University Istanbul School of Medicine, Istanbul, Turkey, 6Istanbul University Faculty of Medicine, Istanbul, Turkey

    Background/Purpose: Recently developed EULAR/ACR classification criteria for systemic lupus erythematosus (SLE) has important differences compared to the 2012 Systemic Lupus International Collaborating Clinics (SLICC) SLE…
  • Abstract Number: 1834 • ACR Convergence 2021

    To What Extent Do Clinical Features of PsA Predict Achievement of Minimal Disease Activity at Week 24: A Post Hoc Analysis of the Phase III Clinical Trial Program of Guselkumab in a Bio-naïve Patient Population

    Marijn Vis1, Pascal Richette2, Ramirez Julio3, Marlies Neuhold4, Robert Wapenaar5, Elke Theander6, Wim Noel7, May Shawi8, Alexa Kollmeier9 and William Tillett10, 1Erasmus MC, Badhoevedorp, Netherlands, 2Lariboisiere Hospital, Paris, France, 3Hospital Universitari Clinic, Barcelona, Spain, 4Janssen-Cilag, Zug, Switzerland, 5Janssen-Cilag BV, Breda, Netherlands, 6Janssen Cilag, Lund, Sweden, 7Janssen Pharmaceutica, Vilvoorde, Belgium, 8Janssen Immunology Global Commercial Strategy Organization, Toronto, ON, Canada, 9Janssen Research & Development, LLC, La Jolla, CA, 10Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom

    Background/Purpose: Guselkumab (GUS), a human monoclonal antibody targeting the interleukin-23p19-subunit, has demonstrated efficacy across joint and skin endpoints at Week 24 (W24) in the Phase…
  • Abstract Number: 0348 • ACR Convergence 2021

    The New EULAR/ ACR 2019 SLE Classification Criteria: A Predictor of Long-term Outcomes

    Laura Whittall-Garcia1, Dafna Gladman2, Murray Urowitz3, Jiandong Su4, Zahi Touma5 and Sindhu Johnson6, 1University of Toronto, University Health Network, Toronto, ON, Canada, 2Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, 3Center for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University of Toronto, Lupus Clinic, Toronto, ON, Canada, 4University Health Network, Toronto, ON, Canada, 5University of Toronto, Mississauga, ON, Canada, 6University of Toronto, Toronto, ON, Canada

    Background/Purpose: We recently demonstrated that a EULAR/ACR classification Criteria score ≥ 20 predicts a higher disease activity throughout the first 5 years after diagnosis. Given…
  • Abstract Number: 1882 • ACR Convergence 2021

    Clinical Characteristics and Reliability of a Self-Reported Diagnosis of Large-Vessel Vasculitis

    Tannaz Kermani1, Jason Springer2, Dianne Shaw3, Kalen Young4, Cristina Burroughs5 and Peter Merkel6, 1University of California Los Angeles, Los Angeles, CA, 2Vanderbilt University Medical Center, Franklin, TN, 3Vasculitis Foundation, Chapel Hill, NC, 4Vasculitis Foundation, Kansas City, MO, 5Health Informatics Institute, Tampa, FL, 6University of Pennsylvania, Philadelphia, PA

    Background/Purpose: To compare the clinical characteristics and determine the reliability of a self-reported diagnosis of giant cell arteritis (GCA) or Takayasu’s arteritis (TAK) from an…
  • Abstract Number: 0349 • ACR Convergence 2021

    Performance of the 2019 EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus in a Predominantly African American Cohort

    Jessica English1, Dulaney Wilson2, Gary Gilkeson2, Jim Oates2 and Diane Kamen2, 1Medical University of South Carolina, Johns Island, SC, 2Medical University of South Carolina, Charleston, SC

    Background/Purpose: Classification criteria for systemic lupus erythematosus (SLE) were recently published by the European League Against Rheumatism (EULAR) and American College of Rheumatology (ACR) to…
  • Abstract Number: 1888 • ACR Convergence 2021

    Usefulness of 2019 ACR/EULAR Classification Criteria (AECC) for IgG4-Related Disease Differs Between Clinical Phenotypes of IgG4-RD

    Gözde Kübra Yardımcı1, Bayram Farisogulları2, Gizem Ayan1, Levent Kilic1, Sule Apraş Bilgen1 and Omer Karadag3, 1Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 2Division of Rheumatology, Department of Internal Medicine Faculty of Medicine, Hacettepe University, Ankara, Turkey, 3Hacettepe University, Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Ankara, Turkey

    Background/Purpose: ACR/EULAR Classification criteria for IgG4-related disease (IgG4-RD) newly published [1]. On the other hand, four distinctive phenotypes of IgG4-RD have been described [2]. We…
  • Abstract Number: 0355 • ACR Convergence 2021

    Utilization of a Clinical Data Research Network to Assess Systemic Lupus International Collaborating Clinics Classification Criteria Attributes in Patients with Systemic Lupus Erythematosus

    Noah Forrest1, Kathryn Jackson2, Al'ona Furmanchuk2, Anika Ghosh2, Jennifer Pacheco2, Vesna Mitrovic2, Abel Kho2, Rosalind Ramsey-Goldman2 and Theresa Walunas2, 1Feinberg School of Medicine, Chicago, 2Northwestern University, Chicago, IL

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by a heterogenous clinical phenotype that may present differently over time and between patients, which…
  • Abstract Number: 1945 • ACR Convergence 2021

    Efficacy of Upadacitinib on Psoriatic Arthritis with Axial Involvement Defined by Investigator Assessment and PRO-Based Criteria: Results from Two Phase 3 Studies

    Xenofon Baraliakos1, Roberto Ranza2, Andrew Ostor3, Francesco Ciccia4, Laura Coates5, Simona Rednic6, Jessica Walsh7, Tianming Gao8, Apinya Lertratanakul8, In-Ho Song8, Fabiana Ganz8, Kevin Douglas8 and Atul Deodhar9, 1Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, 2Hospital de Clinicas, Universidade Federal de Uberlândia, Uberlandia, MG, Brazil, 3Monash University, Cabrini Hospital, and Emertius Research, Malvern, Australia, 4University of Campania Luigi Vanvitelli, Napoli, Italy, 5Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 6Emergency Clinical County Hospital, Rheumatology and Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania, 7Salt Lake City Veteran Affairs Medical Center (VAMC)/University of Utah Hospital, Salt Lake City, UT, 8AbbVie Inc., North Chicago, IL, 9Oregon Health & Science University, Portland, OR

    Background/Purpose: Patients with PsA and axial involvement have higher disease activity and greater reductions in quality of life;1 however, there are no accepted criteria for…
  • Abstract Number: 0652 • ACR Convergence 2021

    Application of a GCA Probability Score to Patients Referred to a GCA Fast Track Clinic

    Mmoloki Mathake1, Julia Murdoch2, Andrew Taylor3, Jean-Louis deSousa2, Kathy Jao2, Rachel Li2 and Helen Keen4, 1Fiona Stanley Hospital, Beckenham, Australia, 2Royal Perth Hospital, Perth, Australia, 3Fiona Stanley Hospital, Murdoch, Australia, 4Fiona Stanley Hospital, Perth, Australia

    Background/Purpose: Giant cell arteritis (GCA) is the most common large vessel vasculitis, and may be associated with irreversible blindness(1). It is therefore essential to make…
  • Abstract Number: 0804 • ACR Convergence 2021

    Validation of the 2010 ACR/EULAR Classification Criteria of Rheumatoid Arthritis (RA) in a Nursing-led Triage Clinic

    Ching Man Tsang1, Chi Chiu Mok2, Kar Li Chan3, Sau Mei TSE1 and Ling Yin Ho1, 1Tuen Mun Hospital, Hong Kong, Hong Kong, 2Tuen Mun Hospital, Hong Kong, China, 3Tuen Mun Hospital, Hong Kong

    Background/Purpose: To shorten the waiting time to see rheumatologists, a nurse-led triage clinic was established in our hospital in September 2018 to triage new referrals…
  • Abstract Number: 0903 • ACR Convergence 2021

    Scoring MRI Structural Lesions in Sacroiliac Joints of Patients with Axial Spondyloarthritis: How Many Slices Are Optimal?

    Walter Maksymowych1, Ulrich Weber2, Xenofon Baraliakos3, Pedro Machado4, Susanne Pedersen5, Joachim Sieper6, Stephanie Wichuk7, Denis Poddubnyy8, Martin Rudwaleit9, Désirée van der Heijde10, Robert Landewé11, Joel Paschke12, Mikkel Ostergaard13 and Robert Lambert7, 1Department of Medicine, University of Alberta, Alberta, Canada, Edmonton, AB, Canada, 2Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, 3Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, 4Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, 5Rigshospitalet, Center for Arthritis Research, Glostrup, Denmark, 6Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, 7University of Alberta, Edmonton, AB, Canada, 8Department of Rheumatology, Charité – Universitätsmedizin, Berlin, Germany, 9University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany, 10Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, 11Amsterdam Rheumatology & Clinical Immunology Center, Amsterdam, Netherlands; Zuyderland MC, Heerlen, Netherlands, 12CARE Arthritis, Edmonton, AB, Canada, 13Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, and Department of Clinical Medicine, University of Copenhagen, Glostrup, Denmark

    Background/Purpose: There is no international consensus on the optimal number of slices for evaluation of MRI structural lesions in the SIJ. An “all slice” method…
  • Abstract Number: 0904 • ACR Convergence 2021

    Data-driven Definitions Based on Inflammatory Lesions for a Positive MRI of the Spine Consistent with Axial Spondyloarthritis

    Walter Maksymowych1, Robert Lambert2, Xenofon Baraliakos3, Susanne Pedersen4, Iris Eshed5, Ulrich Weber6, Pedro Machado7, Manouk de Hooge8, Joachim Sieper9, Stephanie Wichuk2, Denis Poddubnyy10, Martin Rudwaleit11, Robert Landewé12, Désirée van der Heijde13 and Mikkel Ostergaard14, 1Department of Medicine, University of Alberta, Alberta, Canada, Edmonton, AB, Canada, 2University of Alberta, Edmonton, AB, Canada, 3Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, 4Rigshospitalet, Center for Arthritis Research, Glostrup, Denmark, 5Sheba Medical Center, Ramat Gan, Israel, 6Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, 7Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, 8Ghent University Hospital, Ghent, Belgium, 9Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, 10Department of Rheumatology, Charité – Universitätsmedizin, Berlin, Germany, 11University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany, 12Amsterdam Rheumatology & Clinical Immunology Center, Amsterdam, Netherlands; Zuyderland MC, Heerlen, Netherlands, 13Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, 14Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, and Department of Clinical Medicine, University of Copenhagen, Glostrup, Denmark

    Background/Purpose: The ASAS definition of a positive MRI for inflammation in the spine (ASAS-MRI+) is intended for classification of patients as having axSpA but is…
  • Abstract Number: 0975 • ACR Convergence 2021

    Data-driven MRI Definitions for Active and Structural Sacroiliac Joint Lesions in Juvenile Spondyloarthritis Typical of Axial Disease

    Pamela Weiss1, Timothy Brandon1, Amita Aggarwal2, Ruben Burgos-Vargas3, Robert Colbert4, Gerd Horneff5, Rik Joos6, Ronald Laxer7, Kirsten Minden8, Angelo Ravelli9, Nicolino Ruperto10, Judith Smith11, Matthew Stoll12, Shirley Tse7, Filip Van den Bosch13, Robert Lambert14, David Biko15, Nancy Chauvin16, Michael Francavilla15, Jacob Jaremko14, Nele Herregods17, Ozgur Kasapcopur18, Mehmet YILDIZ19, Alison Hendry20 and Walter Maksymowych21, 1Children's Hospital of Philadelphia, Philadelphia, PA, 2Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, 3Department of Rheumatology, General Hospital of Mexico, Ciudad de Mxico, Mexico, 4NIH/NIAMS, Bethesda, MD, 5Paediatric Rheumatology International Trials Organisation (PRINTO), Sankt Augustin, Germany, 6Ghent University, Ghent, Belgium, 7SickKids, Toronto, ON, Canada, 8German Rheumatism Research Center, Berlin, Germany, 9Istituto Giannina Gaslini, Genoa, Italy, 10IRCCS Istituto Giannina Gaslini; PRINTO, Clinica Pediatrica e Reumatologia, Genova, Italy, 11University of Wisconsin, Madison, WI, 12University of Alabama at Birmingham, Birmingham, AL, 13Dept. of Rheumatology - Ghent University Hospital, Ghent, Belgium, Ghent, Belgium, 14University of Alberta, Edmonton, AB, Canada, 15University of Pennsylvania, Philadelphia, PA, 16Penn State Health, Hershey, PA, 17Universitair Ziekenhuis Ghent, Ghent, Belgium, 18Istanbul University-Cerrahpasa, Cerrahpasa Medical School, İstanbul, Turkey, 19Istanbul University-Cerrahpasa, Faculty of Medicine, Pediatric Rheumatology, İstanbul, Turkey, 20NZ Familial GI Cancer Service, Auckland, New Zealand, 21Department of Medicine, University of Alberta, Alberta, Canada, Edmonton, AB, Canada

    Background/Purpose: Determining optimal cut-offs for active and structural imaging lesions of juvenile spondyloarthritis (JSpA) with axial disease is important for diagnosis, therapeutic management, and classification.…
  • Abstract Number: 1029 • ACR Convergence 2021

    Evaluation of the EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus in a Population-Based Registry

    Allison Guttmann1, Brendan Denvir1, Jill Buyon2, Martin Aringer3, H. Michael Belmont2, Sara Sahl4, Jane Salmon5, Anca Askanase6, Joan Bathon7, Laura Geraldino8, Yousaf Ali9, Ellen Ginzler10, Chaim Putterman11, Caroline Gordon12, Charles Helmick13, Hilary Parton14 and Peter Izmirly1, 1New York University School of Medicine, New York, NY, 2NYU School of Medicine, New York, NY, 3Rheumatology, Medicine III, University Medical Center & Faculty of Medicine, TU Dresden, Dresden, Germany, 4UCLA-Harbor, Los Angeles, CA, 5Hospital for Special Surgery, New York, NY, 6Columbia University Medical Center, New York, NY, 7Columbia University, New York, NY, 8New York Presbyterian Hospital - Columbia Campus, New York, NY, 9Icahn School of Medicine at Mount Sinai, New York, NY, 10SUNY Downstate Health Sciences University, Brooklyn, NY, 11Albert Einstein College of Medicine, Bronx, NY, 12Rheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom, 13Centers for Disease Control and Prevention, Atlanta, GA, 14New York City Department of Health and Mental Hygiene, Long Island City, NY

    Background/Purpose: The Manhattan Lupus Surveillance Program (MLSP) is a multi-racial/ethnic population-based registry with the primary goal to determine the prevalence and incidence of Systemic Lupus…
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