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Abstract Number: 0092

Diagnosis of Behçet’s Disease: Comparison of Two Sets of Classification Criteria. Application in 111 Patients of a Well-defined Population

David Martinez-Lopez1, Alba Herrero Morant2, Carmen Alvarez-Reguera2, Lara Sanchez-Bilbao2, Inigo Gonzalez-Mazon3, José Luis Martín-Varillas4, Guillermo Suarez-Amorin2, Patricia Setien-Preciados2, Cristina Mata-Arnaiz5, Miguel Ángel González-Gay6 and Ricardo Blanco2, 1Hospital Universitario Marques de Valdecilla, Santander (SPAIN), Spain, 2Hospital Universitario Marques de Valdecilla, Santander, Spain, 3Hospital Universitario Marques de Valdecilla, Bezana, Spain, 4Hospital Sierrallana, Torrelavega, Spain, 5Hospital de Laredo, Santander, Spain, 6Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain

Meeting: ACR Convergence 2020

Keywords: Behçet's Syndrome, classification criteria, Vasculitis

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Session Information

Date: Friday, November 6, 2020

Session Title: Miscellaneous Rheumatic & Inflammatory Diseases Poster I: Diagnosis and Testing

Session Type: Poster Session A

Session Time: 9:00AM-11:00AM

Background/Purpose: Behçet’s disease (BD) is a systemic, chronic, relapsing vasculitis with no pathognomonic diagnostic test. The most widely used classification criteria are those of the International Study Group (ISG) for BD. These criteria were repeatedly found to have low sensitivity. Therefore, the International Criteria for Behçet’s Disease (ICBD) were published in 2014.
Objectives: To compare the ISG with ICBD diagnostic criteria for BD.

Methods: The study included all consecutive 111 patients diagnosed with definitive or possible BD by expert rheumatologists. They were diagnosed at a well-defined population in Northern Spain between 1980 and 2019. The ISG and ICBD diagnostic criteria for BD were applied to and compared among all patients.

Results: We studied 111 patients (62 Women/49 Men), mean age 36.8±13.2 years. BD was diagnosed in 65 (58.5%) by ISGBD criteria and in 86 (77.5%) by ICBD criteria. No significant differences were observed between both criteria (p < 0.001). The overall concordance was fair (Kappa 0.3; p< 0.001). Sensitivity was 58.6% for ICBD criteria and 80.2% for ISG. (TABLE-1)

Conclusion: ICBD criteria exhibit higher sensitivity than ISG criteria. Thus, the application of these new criteria can achieve a more correct and earlier diagnosis of BD.


Disclosure: D. Martinez-Lopez, Lilly, 2; A. Herrero Morant, None; C. Alvarez-Reguera, None; L. Sanchez-Bilbao, None; I. Gonzalez-Mazon, None; J. Martín-Varillas, None; G. Suarez-Amorin, None; P. Setien-Preciados, None; C. Mata-Arnaiz, None; M. González-Gay, None; R. Blanco, None.

To cite this abstract in AMA style:

Martinez-Lopez D, Herrero Morant A, Alvarez-Reguera C, Sanchez-Bilbao L, Gonzalez-Mazon I, Martín-Varillas J, Suarez-Amorin G, Setien-Preciados P, Mata-Arnaiz C, González-Gay M, Blanco R. Diagnosis of Behçet’s Disease: Comparison of Two Sets of Classification Criteria. Application in 111 Patients of a Well-defined Population [abstract]. Arthritis Rheumatol. 2020; 72 (suppl 10). https://acrabstracts.org/abstract/diagnosis-of-behcets-disease-comparison-of-two-sets-of-classification-criteria-application-in-111-patients-of-a-well-defined-population/. Accessed May 29, 2023.
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