ACR Meeting Abstracts

ACR Meeting Abstracts

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Abstracts tagged "Atherosclerosis"

  • Abstract Number: 469 • 2013 ACR/ARHP Annual Meeting

    Anti-TNF Therapy Induces Positive Changes In The Lipoprotein Profile Of RA Patientes. Results Of a Prospective Study

    Jaime Calvo-Alén1, Carmela Baamonde2, Ignacio Villa1, Víctor Martínez-Taboada3, Mario Agudo4 and Juan Gómez-Gerique5, 1Rheumatology, Hospital Universitario Sierrallana, Torrelavega, Spain, 2Biochemistry, Hospital Universitario Sierrallana, Torrelavega, Spain, 3Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 4Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 5Biochemistry, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain

    Background/Purpose: Anti-TNF therapy induces elevations in total cholesterol levels although does not seem to modify the atherogenic index. Otherwise, it appears to have a cardiovascular…
  • Abstract Number: 2780 • 2013 ACR/ARHP Annual Meeting

    Cumulative Exposure To Elevated Inflammatory Markers Is Associated With Increased Burden Of Atherosclerosis In Psoriatic Arthritis Patients: A Cohort Study

    Lihi Eder1, Arane Thavaneswaran2, Vinod Chandran3, Richard J. Cook4 and Dafna D. Gladman3, 1University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 4Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada

    Background/Purpose: Cardiovascular morbidity is increased in patients with psoriatic arthritis (PsA). Traditional cardiovascular risk factors do not fully explain this excessive risk. It is unclear…
  • Abstract Number: 402 • 2013 ACR/ARHP Annual Meeting

    Can Modulators Of Inflammation Serve As Biomarkers For Subclinical Atherosclerosis In Rheumatoid Arthritis?

    Kimberly P. Liang1, Douglas P. Landsittel2, Suresh R. Mulukutla3, Steven E. Reis4, Marc C. Levesque5, Donald M. Jones6, Rachel Gartland7, Ali Shoushtari8, Flordeliza S. Villanueva3, Hunter C. Champion8 and Larry W. Moreland5, 1Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 2Medicine, Biostatistics and Clinical and Translational Science, University of Pittsburgh, Center for Health Care Research Data Center, Pittsburgh, PA, 3Division of Cardiology, University of Pittsburgh, Pittsburgh, PA, 4Division of Cardiology and Department of Clinical and Translational Science, University of Pittsburgh, Pittsburgh, PA, 5Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 6Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 7Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 8Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Rheumatoid arthritis (RA) is independently associated with a higher risk of cardiovascular disease (CVD) and premature atherosclerosis. Mechanisms of atherosclerosis include (1) Endothelial dysfunction/activation mediated…
  • Abstract Number: 2763 • 2013 ACR/ARHP Annual Meeting

    Carotid Atherosclerosis As a Predictor Of Mortality In Rheumatoid Arthritis

    Inmaculada del Rincon1, Roy W. Haas2, Jose Felix Restrepo3, Daniel F. Battafarano4, Daniel H. O'Leary5, Emily Molina1 and Agustin Escalante6, 1Rheumatology, University of Texas Health Science Center, San Antonio, TX, 2Dept. of Medicine-Rheumatology, University of Texas Health Science Center, San Antonio, TX, 3Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 4Medicine / MCHE-MDR, Brooke Army Medical Ctr, San Antonio, TX, 5Radiology, Tufts University-Boston Campus, Boston, MA, 6Dept. of Medicine-Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX

    Background/Purpose: Patients with rheumatoid arthritis (RA) have higher mortality than do persons of the same age and sex without RA. This is due in part…
  • Abstract Number: 384 • 2013 ACR/ARHP Annual Meeting

    Carotid Artery Plaques Are Associated With Coronary Atherosclerosis In Patients With Inflammatory Joint Diseases Independent Of Several Cardiovascular Risk Calculators

    Silvia Rollefstad1, Eirik Ikdahl2, Inge C. Olsen3, Tore K. Kvien4,5, Anne S. Eirheim2, Terje R. Pedersen4,6 and Anne G. Semb2, 1Rhuematology, Diakonhjemmet Hospital, Oslo, Norway, 2Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Faculty of Medicine, University of Oslo, Oslo, Norway, 5Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 6Centre of Preventive Medicine, Oslo University Hospital-Ullevaal, Oslo, Norway

    Background/Purpose: Patients with rheumatoid arthritis (RA) and carotid plaque (CP) have been shown to have increased risk of future acute coronary syndrome. We have established…
  • Abstract Number: 2343 • 2013 ACR/ARHP Annual Meeting

    Assessment Of Subclinical Atherosclerosis (Flow Mediated Dilatation and arterial stiffness) After 24 Weeks Of a Tocilizumab Therapy In 22 Patients With Rheumatoid Arthritis

    Martin Soubrier1, Thomas Frayssac2, Bruno Pereira3, Marion Couderc Sr.4, Coline Daron2, Jean Jacques Dubost5, Sandrine Malochet-Guinamand4, Anne Tournadre4 and Sylvain Mathieu4, 1Rheumatology, CHU CLERMONT-FERRAND, Clermont-Ferrand, France, 2CHU CLERMONT-FERRAND, Clermont-ferrand, France, 3Clinical research department, Clermont-Ferrand, France, 4Rheumatology CHU Gabriel Montpied, Clermont-Ferrand, France, 5Rheumatology, CHU G.-Montpied, Clermont-Ferrand, France

    Background/Purpose:  Increased incidence of cardiovascular diseases and sub-clinical atherosclerosis have been observed in rheumatoid arthritis (RA). Inflammation and  traditional risk factors could be involved in…
  • Abstract Number: 386 • 2013 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis Is Associated With Systemic Inflammation In Coronary Vessels

    Inge A.M. van den Oever1, Alper M. van Sijl1, Umit Baylan2, Michael. T. Nurmohamed1, Alexandre E. Voskuyl1, Hans W. Niessen2 and Suat Simsek3, 1Rheumatology, VU University Medical Center, Amsterdam, Netherlands, 2Pathology, VU University Medical Center, Amsterdam, Netherlands, 3Internal Medicine, Medical Center Alkmaar (MCA), Alkmaar, Netherlands

    Background/Purpose: Patients with a chronic inflammatory disease (CID), particularly rheumatoid arthritis (RA), have an increased risk of fatal myocardial infarction (MI), as compared to the…
  • Abstract Number: 1975 • 2013 ACR/ARHP Annual Meeting

    Cardiovascular Risk Stratification In Rheumatic Diseases : Carotid Ultrasound Is More Sensitive Than Coronary Artery Calcification Score To Detect Subclinical atherosclerosis In Patients With Rheumatoid Arthritis

    Francisco Ortiz-Sanjuán1, Alfonso Corrales2, José Antonio Parra3, Carlos González-Juanatey4, Montserrat Santos5, Javier Rueda6, Ricardo Blanco7, Vanesa Calvo-Río8, Javier Loricera8, Javier Llorca9 and Miguel A González-Gay10, 1Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV. Santander. Spain, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, 3Radiology Division, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 4Cardiology Division, Hospital Lucus Augusti, Lugo, Spain, 5Hospital Universitario Marqués de Valdecilla. IFIMAV. Santander. Spain, Santander, Spain, 6Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 7Hospital Marques de Valdecilla, Santander, Spain, 8Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, 9Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), Santander, Spain, 10Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Santander, Spain

    Background/Purpose: Rheumatoid arthritis (RA) is a disease associated to accelerated atherogenesis leading to increased incidence of cardiovascular (CV) mortality. Adequate stratification of the CV risk…
  • Abstract Number: 387 • 2013 ACR/ARHP Annual Meeting

    Left Ventricular Myocardial Tissue In Rheumatoid Arthritis Shows Systemic Inflammation After Fatal Myocardial Infarction 

    Inge A.M. van Den Oever1, Alper M. van Sijl1, Umit Baylan2, Michael. T. Nurmohamed1, Alexandre E. Voskuyl1, Hans W. Niessen2 and Suat Simsek3, 1Rheumatology, VU University Medical Center, Amsterdam, Netherlands, 2Pathology, VU University Medical Center, Amsterdam, Netherlands, 3Internal Medicine, Medical Center Alkmaar (MCA), Alkmaar, Netherlands

    Background/Purpose: Patients with a chronic inflammatory disease (CID), particularly rheumatoid arthritis (RA), have an increased risk of fatal myocardial infarction (MI) and a diminished survival…
  • Abstract Number: 596 • 2012 ACR/ARHP Annual Meeting

    Evolution of Atherosclerosis in Psoriatic Arthritis: Is the Former an Independent Inflammatory Process?

    Roberta Ramonda1, Massimo Puato2, Valentina Modesti3, Mariagrazia Lorenzin4, Paola Frallonardo4, Augusta Ortolan4, Carla Campana3, Alessandro Lo Nigro3 and Leonardo Punzi5, 1Rheumatology Unit, University of Padova, Padova, Italy, 2Department of Internal Medicine, University of Padova, Padova, Italy, 3Unit of Rheumatology, University of Padova, Padova, Italy, 4Rheumatology Unit, Department of Medicine, University of Padova, Padova, Italy, 5Clinical and Experimental Medicine, Rheumatology Unit - University of Padova, Padova, Italy

    Background/Purpose: A non-invasive study focusing on the structural and functional properties of the carotid arteries was carried out in psoriatic arthritis (PsA) patients. Increased cardiovascular…
  • Abstract Number: 1262 • 2012 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis Patients with Higher Disease Severity and Subclinical Carotid Plaque Experience More Cardiovascular Events Despite a Favorable Conventional Cadiovascular Risk Profiles

    Yeon-Ah Lee1, Somi Kim1, Sang-Hoon Lee2, Ran Song2, Hyung In Yang2 and Seung-Jae Hong1, 1Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Seoul, South Korea, 2Rheumatology, Hospital at GANGDONG, Kyung Hee University, Seoul, South Korea

    Background/Purpose: It has been shown that patients with rheumatoid arthritis (RA) experience cardiovascular (CV) events more often than expected. Increased risks of CV diseases in…
  • Abstract Number: 629 • 2012 ACR/ARHP Annual Meeting

    Inflammatory Biomarkers of Atherosclerosis and Oxidative Stress Are Associated with Disease Flare in SLE

    Maureen A. McMahon1, Jennifer M. Grossman1, Brian Skaggs2, Elaine Lourenco2, Cheryl Lee1, Lori Sahakian3, John FitzGerald4, Christina Charles-Schoeman5, Alan H. Gorn6, George A. Karpouzas7, Michael H. Weisman8, Daniel J. Wallace9, Weiling Chen1 and Bevra H. Hahn6, 1Div of Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, 2Medicine/Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, 3Division of Rheumatology, Department of Medicine,, UCLA David Geffen School of Medicine, Los Angeles, CA, 4Medicine-Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, 5University of California, Los Angeles, CA, 6Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, 7Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, 8Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 9Cedars-Sinai Medical Center, Los Angeles, CA

    Background/Purpose: Although our current serologic measures of disease activity are useful for predicting flare in some patients, other patients experience disease flare in the absence…
  • Abstract Number: 1261 • 2012 ACR/ARHP Annual Meeting

    Epicardial Adipose Tissue Is Associated with Cardiometabolic Risk and the Metabolic Syndrome in Patients with Rheumatoid Arthritis

    Michelle J. Ormseth1, Aliza Lipson2, Nikolaos Alexopoulos3, Gregory R. Hartlage3, Annette M. Oeser4, Aihua Bian4, Tebeb Gebretsadik5, Ayumi Shintani4, Paolo Raggi6 and C. Michael Stein7, 1Rheumatology, Vanderbilt Medical Center, Nashville, TN, 2Rheumatology, Emory University, Atlanta, GA, 3Emory University, Atlanta, GA, 4Vanderbilt Medical Center, Nashville, TN, 5Biostatistics, Vanderbilt University, Nashville, TN, 6University of Alberta, Edmonton, AB, Canada, 7School of Medicine, Division of Clinical Pharmacology, Vanderbilt Medical Center, Nashville, TN

    Background/Purpose: Patients with rheumatoid arthritis (RA) have increased coronary atherosclerosis and this may be related to their increased prevalence of visceral adiposity, insulin resistance, and…
  • Abstract Number: 647 • 2012 ACR/ARHP Annual Meeting

    Adjusted Framingham Risk Factor Scoring for Systemic Lupus Erythematosus: Results from an Inception Cohort Followed for Eight Years

    Murray B. Urowitz1, Dominique Ibanez1, D. D. Gladman2, SLICC3 and Systemic Lupus International Collaborating Clinics (SLICC)3, 1Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, 3Division of Rheumatology, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose : There is a high prevalence of premature atherosclerosis among patients with SLE, with a risk 7-9  times that of the general population. The…
  • Abstract Number: 1259 • 2012 ACR/ARHP Annual Meeting

    Association Between Subclinical Atherosclerosis and Bone Mineral Density in Rheumatoid Arthritis

    Barry J. Sheane1, Ruth Dunne2, Ken Scott3, Mary Hall4, Michelle O'Connor2, Martin Healy5, John Feely4, J.B. Walsh6 and Gaye Cunnane7, 1Rheumatology, St. James Hospital, Dublin, Ireland, 2Diagnostic Imaging Department, St James's Hospital, Dublin 8, Ireland, 3Department of Pharmacology and Therapeutics, Trinity College Dublin, Dublin 8, Ireland, 4Department of Pharmacology and Therapeutics, St James's Hospital, Dublin 8, Ireland, 5Central Pathology Laboratory, Dublin 8, Ireland, 6Medicine for the Elderly, Dublin 8, Ireland, 7Dept of Rheumatology, St James's Hospital, Dublin, Ireland

    Background/Purpose: Rheumatoid arthritis (RA) is associated with a higher risk of osteoporosis (OP) and cardiovascular disease (CVD). This cross-sectional study was undertaken to identify links…
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