Abstracts tagged "Arthritis"

Abstract Number: 1994 • 2017 ACR/ARHP Annual Meeting
Erosion Depth Predicts Erosion Progression in Patients with Early RA: A Longitudinal Analysis Using HR-pQCT
Jiang YUE¹, James F Griffith², Fan XIAO³, Jiankun XU⁴, Ling Qin⁵ and Lai-Shan Tam⁶, ¹Department of Medicine & Therapeutics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong, ²Department of Imaging and Interventional Radiology, The Prince of Wales Hospital, The Chinese University of Hong Kong, HONGKONG, Hong Kong, ³Department of Imaging and Interventional Radiology, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong, ⁴Department of Orthopedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong, ⁵Bone Quality and Health Centre of the Department of Orthopaedics and Traumatology, The Prince of Wales Hospital, The Chinese University of Hong Kong, hongkong, Hong Kong, ⁶Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
Background/Purpose: To ascertain the predictors of erosion progression in patients with early RA using high-resolution peripheral quantitative computed tomography (HR-pQCT). Methods: In this prospective study,…
Abstract Number: 381 • 2017 ACR/ARHP Annual Meeting
Down’s Arthritis (DA) – Clinical and Radiological Features of Arthritis in Children with Trisomy 21
Charlene Foley, Emma Jane Mac Dermott and Orla Killeen, National Centre for Paediatric Rheumatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland
Background/Purpose: Down's Arthritis (DA) was first reported in the literature in 1984. Crude estimates suggest higher incidence and prevalence rates of DA compared with Juvenile…
Abstract Number: 2069 • 2017 ACR/ARHP Annual Meeting
Gout Is More Frequent in Sickle Cell Disease Than the General Population
Richard Akintayo¹, Olufemi Adelowo², Adindu Chijioke¹, Timothy Olanrewaju¹, Kehinde Olufemi-Aworinde³ and Foluke Akintayo⁴, ¹Internal Medicine, University of Ilorin Teaching Hospital, Ilorin, Nigeria, ²Arthrimed Specialist Clinic:The Arthritis Centre, Lagos, Nigeria, ³Haematology, Bowen University Teaching Hospital, Ogbomosho, Nigeria, ⁴Family Medicine, Ladoke Akintola University of Technology Teaching Hospital, Ogbomosho, Nigeria
Background/Purpose: Despite the well known risk of hyperuricaemia in Sickle Cell Disease (SCD), it has not been determined if these patients are more prone to…
Abstract Number: 386 • 2017 ACR/ARHP Annual Meeting
Analysis of the Effectiveness of Immunization with Pneumococcal Polysaccharide Vaccine in Children with Juvenile Idiopathic Arthritis
Ekaterina Alexeeva^1,2, Tatiana Dvoryakovskaya¹, Rina Denisova¹, Olga Lomakina¹, Ksenia Isaeva¹, Margarita Soloshenko¹, Anna Karaseva¹, Nikolay Mayansky³, Irina Zubkova³, Darija Novikova⁴, Anna Gayvoronskaya⁴, Natalia Tkachenko⁴, Marika Ivardava⁴, Firuza Shakhtakhtinskaya⁴ and Marina Fedoseenko⁴, ¹Reumatology department, Federal State Autonomous Institution"National Scientific and Practical Center of Children's Health"Of the Ministry of Health of the Russian Federation, Moscow, Russian Federation, ²Pediatrics, The Federal State Autonomous Educational Institution of Higher Education The First Moscow State Medical University named after I.M. Sechenov Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russian Federation, ³Clinical laboratory, Federal State Autonomous Institution"National Scientific and Practical Center of Children's Health"Of the Ministry of Health of the Russian Federation, Moscow, Russian Federation, ⁴Department of Vaccine Prevention, Federal State Autonomous Institution"National Scientific and Practical Center of Children's Health"Of the Ministry of Health of the Russian Federation, Moscow, Russian Federation
Background/Purpose: Juvenile idiopathic arthritis (JIA) is one of the most frequent and most disabling rheumatic diseases in childhood. Children suffering from JIA receiving immunosuppressive and…
Abstract Number: 2124 • 2017 ACR/ARHP Annual Meeting
Mixed Connective Tissue Disorder Has Higher Prevalence of Arthritis and Use of Methotrexate Than Systemic Lupus Erythematosus
Gunasekaran Sambandam^1,2, Dr. Varun Dhir³, Dr. Mahesh Prakash⁴, Ranjana Minz⁵, Shefali Sharma⁶ and Aman Sharma⁷, ¹Internal Medicine, Post Graduate Institute of Medical Education and Research (PGIMER), chandigarh, India, ²Internal medicine, Post graduate Institute of medical education and research, chandigarh, India, ³Internal Medicine ( Clinical Rheumatology), Post Graduate Institute of Medical Education and Research, chandigarh, India, ⁴Radio Diagnosis, Post Graduate Institute of Medical Education and Research, chandigarh, India, ⁵Department of Immunopathology,, PGIMER,, Chandigarh, India, ⁶Department of Medicine, All India Institute of Medical Sciences, New Delhi, New Delhi, India, ⁷Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Background/Purpose: Mixed connective disease is a multi-system disorder with overlapping features of SLE, rheumatoid arthritis, scleroderma and polymyositis/dermatomyositis with high titres of U1 RNP. Arthritis…
Abstract Number: 387 • 2017 ACR/ARHP Annual Meeting
F4/80hi Synovial Macrophages in the Pathogeneses of Spontaneous Inflammatory Arthritis in CD11c-Flip-KO (HUPO) Mice
Qi Quan Huang^1,2, Renee E. Doyle², Philip J. Homan¹, Harris Perlman³, Deborah R. WInter⁴ and Richard M. Pope², ¹Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Medicine/Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Department of Medicine Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Synovial tissue macrophages (STMs) are critical in the pathogenesis of rheumatoid arthritis (RA). During homeostasis, the majority of murine synovial tissue resident macrophages (TRMs)…
Abstract Number: 2130 • 2017 ACR/ARHP Annual Meeting
Joint Manifestations in Patients Diagnosed with Idiopathic Inflammatory Myopathy: Multicenter Registry on Inflammatory Myositis from the Rheumatology Society in Madrid, Spain
Larissa Valor¹, Diana Hernández-Flórez², Julia Martínez-Barrio³, Beatriz E. Joven⁴, Laura Nuño⁵, Carmen Larena⁶, Irene Llorente⁷, Carmen Barbadillo⁸, Paloma Garcia De La Peña⁹, Lucía Ruíz Gutiérrez¹⁰, Henry Moruno Cruz¹¹, Tatiana Cobo-Ibáñez¹², Raquel Almodóvar González¹³, Leticia Lojo¹⁴, MARIA JESUS GARCIA DE YEBENES Y PROUS¹⁵ and Francisco Javier López Longo¹⁶, ¹Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain, ²Rheumatology, Gregorio Marañón University General Hospital, Madrid, Spain, ³Servicio de Reumatologia, Hospital General Universitario Gregorio Marañón, Madrid, Spain, ⁴Rheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain, ⁵Servicio de Reumatologia, Hospital Universitario La Paz, Madrid, Spain, ⁶Hospital Gregorio Marañón, Madrid, Spain, ⁷Rheumatology, H.U. La Princesa, Madrid, Spain, ⁸Hospital Universitario Puerta de Hierro, Madrid, Spain, ⁹Rheumatology, Hospital Madrid Norte Sanchinarro, Madrid, Spain, ¹⁰Pediatric Rheumathology Unit, University Children's Hospital Niño Jesús, Madrid, Spain, ¹¹University Hospital Príncipe de Asturias, Immune System Diseases, Rheumatology department, Alcalá de Henares, Madrid, Spain, ¹²Hospital Universitario Reina Sofía, Universidad Europea de Madrid, Madrid, Spain, ¹³Rheumatology Unit, Hospital Universitario Fundación Alcorcón, Madrid, Spain, ¹⁴Rheumatology, Hospital Universitario La Paz, Spain, Spain, ¹⁵Institute for Musculoskeletal Health, Madrid, Spain, ¹⁶Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain
Background/Purpose: Idiopathic inflammatory myopathies (IIM) comprise a heterogeneous group of autoimmune conditions characterized by muscle non-suppurative inflammation, progressive muscle weakness and a variety of extra-muscular…
Abstract Number: 402 • 2017 ACR/ARHP Annual Meeting
Alteration of the Intestinal Microbiome in the Preclinical Phase of Experimental Arthritis and the Efficacy of Microbiota Modulation in Established Arthritis in Mice
Rebecca Rogier¹, Heather Evans-Marin², Julia Manasson³, Peter M. van der Kraan⁴, Wim B. van den Berg⁵, Marije I. Koenders⁴, Jose U. Scher⁶ and Shahla Abdollahi-Roodsaz^7,8, ¹Experimental Rheumatology, Radboud University Medical Center, Nijmegen, Netherlands, ²Division of Rheumatology, New York University School of Medicine, New York, NY, ³Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ⁴Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ⁵Rheumatology Research and Advanced Therapeutics, Radboud University Medical Center, Nijmegen, Netherlands, ⁶New York University School of Medicine, New York, NY, ⁷Department of Medicine, Division of Rheumatoogy, New York University School of Medicine, New York, NY, ⁸Rheumatology, Radboud University Medical Center, Nijmegen, Netherlands
Background/Purpose: The composition of intestinal microbiota is perturbed in patients with new-onset and chronic rheumatoid arthritis (RA). However, it is not known whether the changes…
Abstract Number: 2221 • 2017 ACR/ARHP Annual Meeting
Eradication of Hepatitis C Among US Veterans: Examination of Changes in Pain Severity and Prescription Opioid Use Following Treatment
Anand Kumthekar¹, Sarah Shull², Benjamin Morasco^3,4, Travis Lovejoy^3,4, Michael Chang² and Jennifer Barton³, ¹Rheumatology, Oregon Health & Science University, Portland, OR, ²Gastroenterology, VA Portland Health Care System, Portland, OR, ³VA Portland Health Care System, Portland, OR, ⁴Oregon Health & Science University, Portland, OR
Background/Purpose: Hepatitis C virus (HCV) is associated with chronic wide spread pain, fatigue, myalgia, arthritis, sicca symptoms and vasculitis. Data regarding prior interferon-based treatment of…
Abstract Number: 731 • 2017 ACR/ARHP Annual Meeting
Prediction of Progression of Interstitial Lung Disease in Patients with Systemic Sclerosis
Wanlong Wu¹, Suzana Jordan², Mike Oliver Becker³, Rucsandra Dobrota³, Shuang Ye⁴, Britta Maurer⁵ and Oliver Distler², ¹Department of Rheumatology, Center of Experimental Rheumatology, University Hospital Zurich; Department of Rheumatology, Renji Hospital South Campus, Shanghai Jiao Tong University School of Medicine, Zurich, Switzerland, ²Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ³Department of Rheumatology, Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁴Department of Rheumatology, Renji Hospital South Campus, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, ⁵Department of Rheumatology, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland
Background/Purpose: No data are available to distinguish between progressive and stable patients when mild lung fibrosis is diagnosed in systemic sclerosis (SSc) patients. This study…
Abstract Number: 2229 • 2017 ACR/ARHP Annual Meeting
The Effect of Intra-Articular Neurotoxin on Arthritis Pain and Substance P Expression in the Dorsal Root Ganglion: Results from Murine Arthritis Models
Hollis Krug^1,2, Sandra Frizelle³, Nicole Blanshan⁴, Christopher W. Dorman³ and Maren Mahowald^2,5, ¹Medicine, Minneapolis VAHCS, Minneapolis, MN, ²Medicine, University of Minnesota Medical School, Minneapolis, MN, ³Research, Minneapolis VA Health Care System, Minneapolis, MN, ⁴Research, Minneapolis VAHCS, Minneapolis, MN, ⁵Rheumatology/ Dept of Medicine, Minneapolis VA and Univ MN Med School, SAINT PAUL, MN
Background/Purpose : Substance P (SP) release and binding to NK-1 produces pain transmission. Neurotoxins (NT) that prevent release of SP, such as onabotulinum toxin (BoNT/A),…
Abstract Number: 144 • 2017 Pediatric Rheumatology Symposium
Linear Discriminant Analysis of Cultured Fibroblast-like Synoviocytes Identifies 6 Candidate Genes Which Predict Extended Course in Juvenile Idiopathic Arthritis
AnneMarie Brescia¹, Megan Simonds², Suzanne M. McCahan³, Timothy Bunnell³, Kathleen E. Sullivan⁴ and Carlos D. Rosé⁵, ¹Pediatric Rheumatology, Nemours A.I. duPont Hospital for Children, Wilmington, DE, ²Nemours, Nemours Biomedical Research, Wilmington, DE, ³Nemours Biomedical Research, Wilmington, DE, ⁴Allergy Immunology, The Children's Hospital of Philadelphia, Philadelphia, PA, ⁵Pediatric Rheumatology, Nemours/Thomas Jefferson University, Wilmington, DE
Background/Purpose: The goal of this project is the identification of informative synovial biomarkers to predict which children with oligoarticular juvenile idiopathic arthritis (JIA) will have…
Abstract Number: 58 • 2017 Pediatric Rheumatology Symposium
Analysis and Implications of Non-Invasive Knee Acoustical Emissions in Juvenile Idiopathic Arthritis
Daniel Whittingslow^1,2, Beren Semiz³, Lori Ponders⁴, Andrew Wiens⁵, Omer Inan^3,6 and Sampath Prahalad⁷, ¹Emory University School of Medicine, Atlanta, GA, ²Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, ³Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, ⁴Emory University, Atlanta, GA, ⁵Computer Science, Cornell University, Ithaca, NY, ⁶Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, ⁷Pediatrics, Emory Children's Center, Atlanta, GA
Background/Purpose: Juvenile Idiopathic Arthritis (JIA), the most common chronic rheumatic disease occurring in childhood, is an important cause of disability. Despite the persistence of disease…
Abstract Number: 143 • 2017 Pediatric Rheumatology Symposium
Influence of Age and Sex on Collagen-Induced Arthritis
Tracy Wilson-Gerwing¹, Arash Panahifar², David M.L. Cooper² and Alan Rosenberg¹, ¹Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, ²Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK, Canada
Background/Purpose: Age and sex differences are found in certain subsets of juvenile idiopathic arthritis (JIA). Collagen Induced Arthritis (CIA) in rodents has utility in assessing…
Abstract Number: 146 • 2017 Pediatric Rheumatology Symposium
Age-Related Differences in Neuronal High Mobility Group Box-1 and Resolvin D1 Receptors in Collagen-Induced Arthritis
Tracy Wilson-Gerwing and Alan Rosenberg, Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada
Background/Purpose: More thorough understanding of age-related molecular interactions that drive inflammation and inflammatory pain is required to help guide evidenced-based, age appropriate treatment strategies that…

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