Abstract Number: 2229 • 2017 ACR/ARHP Annual Meeting
The Effect of Intra-Articular Neurotoxin on Arthritis Pain and Substance P Expression in the Dorsal Root Ganglion: Results from Murine Arthritis Models
Background/Purpose : Substance P (SP) release and binding to NK-1 produces pain transmission. Neurotoxins (NT) that prevent release of SP, such as onabotulinum toxin (BoNT/A),…Abstract Number: 1020 • 2017 ACR/ARHP Annual Meeting
The Inflammatory and Proliferative Synovial Lesion in Post-Infectious Lyme Arthritis Results from Impaired Wound Healing
Background/Purpose: Lyme arthritis (LA) is initially triggered by Borrelia burgdorferi infection, but in some patients, the synovitis persists despite 2-3 months of antibiotic therapy and…Abstract Number: 2231 • 2017 ACR/ARHP Annual Meeting
MCC22, a Novel Compound That Targets Both CCR5 and Mu Opioid Receptors, Is Highly Effective in Treating Inflammatory Arthritis Pain
Background/Purpose: The pain that accompanies rheumatoid arthritis and other chronic inflammatory conditions is difficult to manage. Although opioids provide potent analgesia, chronic opioid use is…Abstract Number: 1308 • 2017 ACR/ARHP Annual Meeting
Answering Reproductive Health Questions That Your Patients Want to Know: Impediments to Family Building and Risks of Contraception
Background/Purpose: Women with arthritis wonder whether they will be able to have the children they desire. They also worry that oral contraceptives may worsen their…Abstract Number: 2239 • 2017 ACR/ARHP Annual Meeting
The Recall Program: Data from a Multicenter Educational Event on Patients with Rheumatoid Arthritis
Background/Purpose: ultrasound (US) is able to show subclinical synovitis in patients (pts) with rheumatoid arthritis (RA) who are in clinical remission (CR); this has been…Abstract Number: 67 • 2017 ACR/ARHP Annual Meeting
The Oxygen Sensor PHD1 Is an Indispensable Regulator of Arthritis Development
Background/Purpose: Oxygen supply is a fundamental requirement for all living tissues. Some tissues such as articular joints are characterized by a physiological state of hypoxia.…Abstract Number: 1321 • 2017 ACR/ARHP Annual Meeting
Inhibition of the Mechanistic Target of Rapamycin Pathway and Glutaminolysis Facilitates the Expansion of Myeloid-Derived Suppressor Cells and Synergistically Ameliorates Arthritis in SKG Mice
Background/Purpose: Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature cells that increase in the pathological state such as tumor or inflammation and have…Abstract Number: 2265 • 2017 ACR/ARHP Annual Meeting
Survey on Gout-Related Knowledge and Perception in Inpatient Setting on Hospitalized Patients with Gout
Background/Purpose: The increasing global burden of gout disease and its impact on the patient’s quality of life calls for new strategies in management. Even though…Abstract Number: 234 • 2017 ACR/ARHP Annual Meeting
Impact of Arthritis Among Populations with Chronic Health Conditions in Rural Counties of the United States – 2015
Background/Purpose: US rural populations have well documented health disparities, including higher prevalence of chronic health conditions; however, arthritis prevalence among those with other chronic conditions…Abstract Number: 1322 • 2017 ACR/ARHP Annual Meeting
Tissue Folate Dysregulation Is Associated with Disease Activity and Methotrexate Response in Collagen-Induced Arthritis
Background/Purpose: Methotrexate (MTX) is an anti-metabolite inhibitor of folate-dependent biochemical pathways and is effective in reducing disease activity in autoimmune arthritis. This work seeks to…Abstract Number: 2709 • 2017 ACR/ARHP Annual Meeting
Histone Deacetylase 1 (HDAC1): A Novel Therapeutic Target for Patients with Rheumatoid Arthritis
Background/Purpose: Autoreactive T cells drive the inflammatory process, which leads to an irreversible destruction of the joints. Gene transcription and regulation of proinflammatory cytokine production…Abstract Number: 143 • 2017 Pediatric Rheumatology Symposium
Influence of Age and Sex on Collagen-Induced Arthritis
Background/Purpose: Age and sex differences are found in certain subsets of juvenile idiopathic arthritis (JIA). Collagen Induced Arthritis (CIA) in rodents has utility in assessing…Abstract Number: 146 • 2017 Pediatric Rheumatology Symposium
Age-Related Differences in Neuronal High Mobility Group Box-1 and Resolvin D1 Receptors in Collagen-Induced Arthritis
Background/Purpose: More thorough understanding of age-related molecular interactions that drive inflammation and inflammatory pain is required to help guide evidenced-based, age appropriate treatment strategies that…Abstract Number: 153 • 2017 Pediatric Rheumatology Symposium
Training pediatric rheumatology fellows intra-articular injection techniques and skills using a cadaver based musculoskeletal curriculum
Background/Purpose: Intra-articular injections are important to treat children with arthritis. Practice differences, comfort levels, and reimbursement can decrease fellow exposure to this skill. The purpose…Abstract Number: 144 • 2017 Pediatric Rheumatology Symposium
Linear Discriminant Analysis of Cultured Fibroblast-like Synoviocytes Identifies 6 Candidate Genes Which Predict Extended Course in Juvenile Idiopathic Arthritis
Background/Purpose: The goal of this project is the identification of informative synovial biomarkers to predict which children with oligoarticular juvenile idiopathic arthritis (JIA) will have…
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