Abstracts tagged "Arthritis"

Abstract Number: 2239 • 2017 ACR/ARHP Annual Meeting
The Recall Program: Data from a Multicenter Educational Event on Patients with Rheumatoid Arthritis
Andrea Delle Sedie¹, Emilio Filippucci², Oscar Epis³, Pierluigi Macchioni⁴, Sebastiano Tropea⁵, Carlo Bonali⁶, Marco Canzoni⁷ and Annamaria Iagnocco⁸, ¹Department Rheumatology, University of Pisa, Pisa, Italy, ²Rheumatology Unit, Università Politecnica delle Marche, Jesi, Italy, ³Rheumatology Unit, Ospedale Niguarda, Milano, Italy, ⁴Arcispedale Santa Maria Nuova, Reggio Emilia, Italy, ⁵ASP7, Busacca Hospital, Ragusa, Italy, ⁶Rheumatology Unit,, Ospedale San Paolo, Bari, Italy, ⁷Local Health Unit (ASL) Rome 1, Rome, Italy, ⁸Academic Rheumatology Unit, Università degli Studi di Torino, Torino, Italy
Background/Purpose: ultrasound (US) is able to show subclinical synovitis in patients (pts) with rheumatoid arthritis (RA) who are in clinical remission (CR); this has been…
Abstract Number: 67 • 2017 ACR/ARHP Annual Meeting
The Oxygen Sensor PHD1 Is an Indispensable Regulator of Arthritis Development
Katelijne De Wilde¹, Peggy Jacques² and Dirk Elewaut³, ¹Inflammation Research Center - VIB UGhent, Molecular Immunology and Inflammation Unit, Ghent, Belgium, ²Ghent University Hospital, Ghent, Belgium, ³VIB Inflammation Research Center, University of Ghent, Ghent, Belgium
Background/Purpose: Oxygen supply is a fundamental requirement for all living tissues. Some tissues such as articular joints are characterized by a physiological state of hypoxia.…
Abstract Number: 1321 • 2017 ACR/ARHP Annual Meeting
Inhibition of the Mechanistic Target of Rapamycin Pathway and Glutaminolysis Facilitates the Expansion of Myeloid-Derived Suppressor Cells and Synergistically Ameliorates Arthritis in SKG Mice
Yo Ueda¹, Takaichi Okano¹, Hirotaka Yamada¹, Yoshihide Ichise¹, Ikuko Naka², Soshi Takahashi³, Sho Sendo⁴, Kengo Akashi², Akira Onishi⁵, Jun Saegusa⁴ and Akio Morinobu³, ¹Department of Rheumatology and Clinical immunology, Kobe University Graduate School of Medicine, Kobe, Japan, ²Kobe University Graduate School of Medicine, Kobe, Japan, ³Department of Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan, ⁴Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan, ⁵Rheumaology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan
Background/Purpose: Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature cells that increase in the pathological state such as tumor or inflammation and have…
Abstract Number: 2265 • 2017 ACR/ARHP Annual Meeting
Survey on Gout-Related Knowledge and Perception in Inpatient Setting on Hospitalized Patients with Gout
Roshanak Habibi¹, David T Liss², Sreelakshmi Panginikkod¹, Alvaro Altamirano Ufion³, Ehsan Rajabirostami¹ and Manish Jain⁴, ¹Internal Medicine, Presence Saint Francis Hospital, Evanston, IL, ²Northwestern University, Chicago, IL, ³Internal Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL, ⁴Rheumatology, Presence Saint Francis Hospital, Evanston, IL
Background/Purpose: The increasing global burden of gout disease and its impact on the patient’s quality of life calls for new strategies in management. Even though…
Abstract Number: 234 • 2017 ACR/ARHP Annual Meeting
Impact of Arthritis Among Populations with Chronic Health Conditions in Rural Counties of the United States – 2015
Michael Boring¹, Louise Murphy², Jennifer M. Hootman³ and Yong Liu², ¹Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ²Division of Population Health, Centers for Disease Control and Prevention, Atlanta, GA, ³Centers for Disease Control and Prevention, Kennesaw, GA
Background/Purpose: US rural populations have well documented health disparities, including higher prevalence of chronic health conditions; however, arthritis prevalence among those with other chronic conditions…
Abstract Number: 1322 • 2017 ACR/ARHP Annual Meeting
Tissue Folate Dysregulation Is Associated with Disease Activity and Methotrexate Response in Collagen-Induced Arthritis
Leon van Haandel¹, Rakesh Singh², Paul Kiptoo³, Teruna Siahaan³, Mara L Becker⁴ and Ryan Funk⁵, ¹2401 Gillham Road, Children's Mercy, Kansas City, MO, ²Department of Pharmacy Practice, University of Kansas Medical Center, Kansas City, KS, ³Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, ⁴Rheumatology, Children's Mercy Kansas City, Kansas City, MO, ⁵University of Kansas Medical Center, Kansas City, KS
Background/Purpose: Methotrexate (MTX) is an anti-metabolite inhibitor of folate-dependent biochemical pathways and is effective in reducing disease activity in autoimmune arthritis. This work seeks to…
Abstract Number: 2709 • 2017 ACR/ARHP Annual Meeting
Histone Deacetylase 1 (HDAC1): A Novel Therapeutic Target for Patients with Rheumatoid Arthritis
Lisa Goschl^1,2, Michael Bonelli³, Victoria Saferding⁴, Teresa Peglej², Sylvia Knapp⁵, Johan Bäcklund⁶, Christoph Bock⁵, Patrick Matthias⁷, Kiyoshi Hirahara⁸, Clemens Scheinecker¹, Günter Steiner⁹, Josef S. Smolen¹ and Wilfried Ellmeier², ¹Medical University of Vienna, Devision of Rheumatology, Vienna, Austria, ²Medical University of Vienna,Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Vienna, Austria, ³Rheumatology, Medical University of Vienna, Vienna, Austria, ⁴Medical University of Vienna, Austria, Vienna, Austria, ⁵CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria, ⁶Karolinska Institute,Department of Medical Biochemistry and Biophysics, Stockholm, Sweden, ⁷Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland, ⁸Department of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan, ⁹Medical University of Vienna, Dvision of Rheumatology, Vienna, Austria
Background/Purpose: Autoreactive T cells drive the inflammatory process, which leads to an irreversible destruction of the joints. Gene transcription and regulation of proinflammatory cytokine production…
Abstract Number: 250 • 2017 ACR/ARHP Annual Meeting
An Ultrasonographic Study for Investigating Relationships with the Signs of Uric Deposition and Bone Erosion in Patients with Hyperuricemia
Ikuko Tanaka¹, Takashi Kato², Motokazu Kai³, Kunikazu Ogawa³, Hisaji Oshima⁴ and Shigenori Tamaki⁵, ¹NAGOYA Rheumatology Clinic, Nagoya, Japan, ²Department of Radiology, National Center for Geratrics and Gerontology, Obu, Japan, ³Mie Rheumatology Clinic, Suzuka, Japan, ⁴Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan, ⁵Nagoya Rheumatology Clinic, Nagoya, Japan
Background/Purpose: Joint ultrasonography (US) is a noninvasive examination that can evaluate arthritis and uric acid deposition at gout attacks. The purpose of this study was…
Abstract Number: 1323 • 2017 ACR/ARHP Annual Meeting
Crucial Roles for Toll-like Receptor 9 in the Pathogenesis of Erosive Autoimmune Arthritis and during Osteoclastogenesis
Anita Fischer¹, Brigitte Meyer¹, Birgit Niederreiter², Erik Lönnblom³, Rikard Holmdahl⁴ and Günter Steiner², ¹Internal Medicine III, Division of Rheumatology, Medical University Vienna, Vienna, Austria, ²Rheumatology, Medical University of Vienna, Vienna, Austria, ³Department of Medical Biochemistry & Biophysics, Karolinska Institute, Stockholm, Sweden, ⁴Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden
Background/Purpose: Release and insufficient removal of endogenous nucleic acids may be involved in triggering harmful autoimmune reactions important in the initiation of systemic autoimmune diseases…
Abstract Number: 2840 • 2017 ACR/ARHP Annual Meeting
Clinical Presentation and Outcomes in Patients with Prosthetic Joint Septic Arthritis Who Had One-Stage Versus Two-Stage Joint Replacement
Mary Louise Fowler¹, Kevin Byrne², Sarah Lieber³, Robert Shmerling⁴ and Ziv Paz³, ¹2Boston University School of Medicine, Boston, MA, ²Boston University School of Medicine, Boston, MA, ³Beth Israel Deaconess Medical Center, Boston, MA, ⁴Rheumatology, Beth Israel Deaconess Medical Center, Boston, MA
Background/Purpose: Prosthetic joint septic arthritis (PJSA) complicates about 1 to 2 percent of joint replacement surgeries. The management of PJSA usually includes a combination of…
Abstract Number: 277 • 2017 ACR/ARHP Annual Meeting
Rheumatic Conditions Appearing De Novo after Infection with Chikungunya Virus in Venezuelan Patients
Yurilis Fuentes-Silva¹, Carlota Acosta², Luisa Ortega³, Martin A Rodriguez⁴, Soham Al Snih⁵, Ivan Amaya⁶ and Irama Maldonado³, ¹Division of Rheumatology/Internal Medicine Department, 1Unidad de Reumatología adscrita al Centro Nacional de Enfermedades Reumáticas. Complejo Hospitalario Universitario Ruiz y Páez, Ciudad Bolivar, Venezuela (Bolivarian Republic of), ²1Unidad de Reumatología adscrita al Centro Nacional de Enfermedades Reumáticas. Complejo Hospitalario Universitario Ruiz y Páez, Ciudad Bolivar, Venezuela (Bolivarian Republic of), ³Internal Medicine, 1Unidad de Reumatología adscrita al Centro Nacional de Enfermedades Reumáticas. Complejo Hospitalario Universitario Ruiz y Páez, Ciudad Bolivar, Venezuela (Bolivarian Republic of), ⁴Division of Rheumatology/Internal Medicine Department, Centro Nacional de Enfermedades Reumaticas. Hospital Universitario de Caracas, Caracas, Venezuela (Bolivarian Republic of), ⁵University of Texas Medical Branch, Galveston, TX, ⁶Facultad de Bioanálisis. Universidad de Oriente, Cudad Bolivar, Venezuela (Bolivarian Republic of)
Background/Purpose: It is well known that viral infections can trigger autoimmune rheumatic diseases. In 2,014 there was an outbreak of Chikungunya (CHIK) virus infection in…
Abstract Number: 1330 • 2017 ACR/ARHP Annual Meeting
Rhesus Theta Defensin 1 (RTD-1) Suppresses Disease-Associated Genes and Induces Anti-Inflammatory Expression Signature in Synovial Tissues of Rat Model of Rheumatoid Arthritis
Prasad Tongaonkar¹, Vasu Punj², Akshay Subramanian³, Dat Tran³, Katie Trinh⁴, Justin Schaal¹, Percio S. Gulko⁵, Andre Oullette³ and Michael Selsted³, ¹Pathology and Laboratory Medicine, Keck School of Medicine University of Southern California, Los Angeles, CA, ²Medicine, Keck School of Medicine University of Southern California, Los Angeles, CA, ³Keck School of Medicine University of Southern California, Los Angeles, CA, ⁴Pathology, Keck School of Medicine University of Southern California, Los Angeles, CA, ⁵Medicine/Rheumatology, Icahn School of Medicine at Mount Sinai, New York, NY
Background/Purpose: Theta (θ) defensins are the only known macrocyclic peptides found in the Animal kingdom and are exclusively expressed in Old World monkeys. θ-defensins were…
Abstract Number: 2842 • 2017 ACR/ARHP Annual Meeting
Usefulness of Polymerase Chain Reaction for Diagnosing Whipple’S Disease in Rheumatology
Marion Herbette¹, Jean Baptiste Cren², Laurie Joffres³, charlotte lucas⁴, Emilie Ricard⁵, Carine Salliot⁶, Jerome Guinard⁷, Aleth Perdriger⁸, Elisabeth Solau-Gervais⁹, Béatrice Bouvard¹⁰ and Alain Saraux¹¹, ¹Rheumatology, University Hospital, Brest, France, ²Rheumatology, University Hospital of Angers, Angers, France, ³University Hospital de Poitiers, Poitiers, France, ⁴Rheumatology, University Hospital, Rennes, France, ⁵Rheumatology, University Hospital, Orléans, France, ⁶department of Rheumatology, Orleans, France, ⁷Microbiology, CHU Angers, Angers, France, ⁸Service de Rhumatologie, CHRU de Rennes, Rennes, France, ⁹Rhumatologie, University Hospital, Poitiers, France, ¹⁰rheumatology, CHU Angers, Angers, France, ¹¹Rheumatology, Brest University Medical School Hospital, Brest, France
Background/Purpose: Whipple's disease should be considered in patients with recurrent episodes of seronegative arthritis in the large limb, various symptoms (fever, uveitis,...) or biological abnormalities…
Abstract Number: 302 • 2017 ACR/ARHP Annual Meeting
From Monocytes to Macrophages: the Pathogeneses of Spontaneous Inflammatory Arthritis in CD11c-Flip-KO (HUPO) Mice
Qi Quan Huang¹, Renee E. Doyle², Philip J. Homan¹, Harris Perlman³, Deborah R. WInter³ and Richard M. Pope², ¹Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Medicine/Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Department of Medicine Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: We have generated a CD11c-Flip-KO mouse line (HUPO) that spontaneously develops erosive arthritis with incidence 70-80% at age ≥ 20 weeks. This study aimed…
Abstract Number: 1339 • 2017 ACR/ARHP Annual Meeting
Role of Hexokinase-2 in Synovial Lining Hypertrophy in Murine Arthritis
Marta Fernandez Bustmanate¹, Jeffrey Smith², Adam Paul Croft³, Gary S. Firestein⁴, Chris Buckley⁵, Shigeki Miyamoto² and Monica Guma⁶, ¹Medicine, UCSD, San Diego, CA, ²Pharmacology, UCSD, La Jolla, CA, ³Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom, ⁴Medicine, University of California San Diego, La Jolla, CA, ⁵University of Birmingham, Birmingham, United Kingdom, ⁶Medicine, UCSD, La Jolla, CA
Background/Purpose: Recent studies indicate that fibroblast-like synoviocyte (FLS) glucose metabolism is altered in rheumatoid arthritis (RA). Hexokinases (HKs) catalyze the first step in glucose metabolism.…

« Previous Page
1
…
4
5
6
7
8
…
14
Next Page »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].