ACR Meeting Abstracts

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Abstracts tagged "Antibodies"

  • Abstract Number: 726 • 2016 ACR/ARHP Annual Meeting

    Comparison of Infliximab Immunogenicity in Inflammatory Arthritis Versus Inflammatory Bowel Disease Patients in Routine Clinical Practice

    Marianne Guirgis1, Melanie Favre dit Jeanfavre2, Charles Benaim3, Matthieu Perreau4, Pierre Michetti5, Michel Maillard1 and Pascal Zufferey6, 1gastroenterology, Lausanne, Switzerland, 2DAL, RHU, Lausanne, Switzerland, 3DAL, MPR, Lausanne, Switzerland, 4Medecine /CHUV, Immunology, Lausanne, Switzerland, 5La Source-Beaulieu, Lausanne, Switzerland, 6Rhu /Dal .Chuv, Rheumatology, Lausanne, Switzerland

    Background/Purpose: Infliximab is a biological agent frequently used for inflammatory arthritis (IA) such as spondyloarthritis, rheumatoid arthritis, psoriatic arthritis as well as for the inflammatory…
  • Abstract Number: 2905 • 2016 ACR/ARHP Annual Meeting

    Predictors of Poor Hand Function in Systemic Sclerosis

    Ashraf Raslan1 and Vivien Hsu2, 1Medicine, Rutgers-RWJ Medical School, Jersey City, NJ, 2Rheumatology, RWJ Med Schl Scleroderma Prog, New Brunswick, NJ

    Background/Purpose: Systemic Sclerosis (SSc) is a progressive systemic disease that can lead to variable degrees of morbidity and disability. Hand dysfunction in SSc patients [1]…
  • Abstract Number: 830 • 2016 ACR/ARHP Annual Meeting

    Cardiopulmonary Disease Development in Anti-RNA Polymerase III Positive Systemic Sclerosis; Comparative Analyses from an Unselected, Prospective Patient Cohort

    Anna Hoffmann-Vold1, Anders Heiervang Tennøe2, Oyvind Midtvedt2, May Brit Lund3, Torhild Garen2, Fadi El-Hage4, Trond Mogens Aalokken5, Eli Taraldsrud4 and Øyvind Molberg2, 1Division of Rheumatology, Oslo University Hospital, Oslo, Norway, 2Rheumatology, Oslo University Hospital, Oslo, Norway, 3Respiratory Medicine, Oslo University Hospital, Oslo, Norway, 4Oslo University Hospital, Oslo, Norway, 5Radiology, Oslo University Hospital, Oslo, Norway

    Background/Purpose: Extensive skin disease and renal crisis are hallmarks of anti-RNA polymerase III (RNAP) positive systemic sclerosis (SSc), while data on lung and heart involvement…
  • Abstract Number: 3225 • 2016 ACR/ARHP Annual Meeting

    Dual Cytokine Inhibition with ABT-122, a Tnf– and IL-17–Targeted Dual Variable Domain Immunoglobulin (DVD-Ig™): Results from a 24-Week Open-Label Extension Study in Patients with Rheumatoid Arthritis

    Mark C. Genovese1, Michael Weinblatt2, Heikki T. Mansikka3, Paul M. Peloso3, Kun Chen3, Yihan Li3, John Liu3 and Robert J. Padley3, 1Stanford University Medical Center, Palo Alto, CA, 2Brigham and Women’s Hospital, Boston, MA, 3AbbVie Inc., North Chicago, IL

    Background/Purpose: ABT-122 is a dual variable domain immunoglobulin (DVD-Ig™) that targets human tumor necrosis factor-α (TNF-α) and interleukin-17A (IL-17A). The object was to investigate the…
  • Abstract Number: 1011 • 2016 ACR/ARHP Annual Meeting

    Correlations Between B Cell Epitope Specificity and Clinical Features in Patients with Jo-1 Antibodies and the Anti-Synthetase Syndrome

    Joseph LaConti1, Fanny Kippelen2, Rohit Aggarwal3 and Dana P. Ascherman4, 1Division of Rheumatology, University of Miami Miller School of Medicine, Miami, FL, 2Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, 3Department of Medicine / Rheumtology, University of Pittsburgh Medical Center, Pittsburgh, PA, 4Medicine/Rheumatology, University of Miami Miller School of Medicine, Miami, FL

    Correlations Between B Cell Epitope Specificity and Clinical Features in Patients with Jo-1 Antibodies and the Anti-Synthetase Syndrome Background/Purpose: Idiopathic inflammatory myopathy (IIM) is an…
  • Abstract Number: 3243 • 2016 ACR/ARHP Annual Meeting

    Intestinal Microbial Dysbiosis in SLE Is Linked to Elevated IgA and Induction of Autoimmunity

    Doua F. Azzouz1, Lelise Getu2, Celine Anquetil1, Jill P. Buyon3 and Gregg J. Silverman3, 1Medicine, NYU School of Medicine, New York, NY, 2Department of Medicine, New York University School of Medicine, New York, NY, 3Medicine, New York University School of Medicine, New York, NY

    Background/Purpose: SLE is a complex multifactorial systemic autoimmune disease, which has been attributed to poorly understood interactions between genetic and environmental factors. Recent reports have…
  • Abstract Number: 1347 • 2016 ACR/ARHP Annual Meeting

    Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis: Characteristics, Treatment and Outcome in 251 Cases from the Literature

    Charlotte Laurent1, Jean Capron2, Sonia Alamowitch3, Bluenn Quillerou4, Guy Thomas4, Olivier Fain5 and Arsène Mékinian5, 1Internal Medicine, Internal Medicine, Hôpital Saint-Antoine, Paris, paris, France, 2Neurology, Neurology, Hôpital Saint-Antoine, paris, France, 3Neurology, Neurology - Hopital St Antoine, paris, France, 4Psychiatry, Psychiatry Hopital St Antoine, paris, France, 5Service de médecine interne. Hôpital Saint-Antoine., Paris, France

    Background/Purpose: Steroid-responsive encephalopathy and associated autoimmune thyroiditis (SREAT) is characterized by encephalopathy and the presence of antithyroid antibodies. We describe the clinical presentation, outcome and…
  • Abstract Number: 1353 • 2016 ACR/ARHP Annual Meeting

    Risk Factors of Pulmonary Mycobacterium Avium-Comlex (MAC) Disease and the Significance of Anti-MAC Antibody in Patients with Rheumatic Diseases

    Tamao Nakashita1, Shinji Motojima2, Akira Jibatake2, Akira Yoshida2 and Yoshiki Yamamoto2, 1Department of Rheumatology and Allergy, Kameda Medical Center, Kamogawa-city, Japan, 2Department of Rheumatology and Allergy, Kameda Medical Center, Kamogawa city, Japan

    Background/Purpose: Pulmonary MAC disease is caused by MAC and the incidence is increasing in Japan. It is also becoming a great concern in the field…
  • Abstract Number: 1369 • 2016 ACR/ARHP Annual Meeting

    Features Distinguishing Clinically Hypo- and Amyopathic Juvenile Dermatomyositis (CAJDM) from Juvenile Dermatomyositis (JDM)  

    Gulnara Mamyrova1, Takayuki Kishi2, Nastaran Bayat2, Ira N. Targoff3, Lan Wu2, Olcay Y. Jones1,4, Rodolfo Curiel1, Frederick W. Miller2 and Lisa G. Rider1,2, 1Rheumatology, George Washington University, Washington, DC, 2Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, NIH, Bethesda, MD, 3University of Oklahoma, Oklahoma City, OK, 4Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD

    Background/Purpose:   Clinically Amyopathic Juvenile Dermatomyositis (CAJDM) is a distinct clinical phenotype of JDM in which patients (pts) often have characteristic JDM rashes with little…
  • Abstract Number: 1437 • 2016 ACR/ARHP Annual Meeting

    Netrin-1 and Its Receptor Unc5b Are Novel Targets for the Treatment of Inflammatory Arthritis

    Aranzazu Mediero1, Tuere Wilder2, Bhama Ramkhelawon3, Kathryn Moore3 and Bruce Cronstein4, 1Medicine, Divison of Translational Medicine, NYU School of Medicine, New York City, NY, 2Department of Medicine, Division of Rheumatology, NYU School of Medicine, New York, NY, 3Leon H. Charney Division of Cardiology, Department of Medicine,, NYU School of Medicine, New York, NY, 4Medicine, Division of Rheumatology, NYU School of Medicine, New York, NY

    Background/Purpose:  Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation and destruction of joints. Netrin-1, a laminin-like matrix protein that acts as a…
  • Abstract Number: 1667 • 2016 ACR/ARHP Annual Meeting

    Diagnostic Value of Anti-CD74 Antibodies in Axial Spondyloarthritis: Results from a Population with Low HLA-B27 Prevalence Background

    Nelly Ziade1, Fouad Fayad1, Iyad Mallak2, Georges Merheb3, Torsten Witte4 and Xenofon Baraliakos5, 1Rheumatology, Hotel Dieu de France Hospital and Saint Joseph University, Beirut, Lebanon, 2Radiology, Hotel-Dieu de France and Saint-Joseph University, Beirut, Lebanon, 3Internal Medicine, Notre Dame des Secours University Hospital, Jbeil, Lebanon, 4Department of Clinical Immunology and Rheumatology, Hannover Medical School, Hannover, Germany, 5Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany

    Background/Purpose: Axial spondyloarthritis (axSpA) is still frequently diagnosed late and its pathogenesis is still unclear. Although a strong genetic association of axSpA with HLA-B27 is…
  • Abstract Number: 1876 • 2016 ACR/ARHP Annual Meeting

    Prevalence of Anti-RNA Polymerase III IgG Antibody in a Cohort of Patients with Delayed Wound Healing

    Christian Geier1, Sean McNish2 and Victoria K. Shanmugam2, 1Department of Medicine, The George Washington University, Washington, DC, 2Division of Rheumatology, The George Washington University, Washington, DC

    Prevalence of Anti-RNA Polymerase III IgG Antibody in a Cohort of Patients with Delayed Wound Healing Background/Purpose: Anti-RNA polymerase III IgG antibody (Pol3) is associated…
  • Abstract Number: 2454 • 2016 ACR/ARHP Annual Meeting

    Cohort of Pregnant Women with Ro/La Antibodies: Risk of Fetal Third Degree Atrioventricular Block and Use of Hydroxychloroquine

    Florencia Beatriz Mollerach1, Marina Scolnik2, Luis J. Catoggio2 and Enrique R. Soriano1, 1Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 2Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Argentina., Buenos Aires, Argentina

    Background/Purpose: Third degree atrioventricular block(AVB), a rare congenital complication, duplicate-triplicate frequency up to 2% when Ro/La maternal antibodies are present. Incidence rises to 17-20% in…
  • Abstract Number: 633 • 2015 ACR/ARHP Annual Meeting

    Anti-Centromere Antibodies Are Associated with More Severe Exocrine Glandular Dysfunction in Primary Sjögren’s Syndrome: An Analysis of the Sjögren’s International Collaborative Clinical Alliance Cohort

    Alan N. Baer1, Leah Medrano2 and Mara McAdams-Demarco3, 1Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Medicine (Rheumatology), Johns Hopkins University School of Medicine, Baltimore, MD, 3Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD

    Background/Purpose: Anti-centromere antibodies (ACA) define a subgroup of Sjögren’s syndrome (SS) patients who are often older, have more frequent Raynaud’s phenomenon, and a lower frequency…
  • Abstract Number: 2951 • 2015 ACR/ARHP Annual Meeting

    Anti-NR2 Antibody and Blood-Brain Barrier Disruption in Systemic Lupus Erythematosus Patients with Cognitive Dysfunction

    Gaurav Gulati1, Philip Iffland2, Damir Janigro2, Bin Zhang3 and Michael Luggen4, 1Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH, 2Cleveland Clinic Lerner College of Medicine, Cleveland, OH, 3Cincinnati Children's Hospital and Medical Center, Cincinnati, OH, 4Division of Immunology, University of Cincinnati Medical Center, Cincinnati, OH

    Background/Purpose: Cognitive Dysfunction (CD) is one of the most common manifestations of neuropsychiatric SLE (NPSLE) and one of the most devastating. The pathogenesis of CD…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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