Abstracts tagged "Ankylosing spondylitis (AS)"

Abstract Number: 2810 • 2013 ACR/ARHP Annual Meeting
Follow-Up Testing Of Interferon-Gamma Release Assays For The Diagnosis Of Hidden Tuberculosis Infection In Patients Receiving Tumor Necrosis Factor Alpha Antagonists
Chan-Nam Son¹, Tae-Hwan Kim², Il-Hoon Sung³, Jae-Bum Jun² and Dae-Hyun Yoo², ¹Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, South Korea, ²Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ³Orthopaedic surgery, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Background/Purpose: Anti-tumor necrosis factor alpha (Anti-TNFα) therapy is often used in patients with rheumatic diseases who do not respond to conventional treatment. Risk of tuberculosis…
Abstract Number: 2443 • 2013 ACR/ARHP Annual Meeting
Prevalence Of Coronary Heart Disease In Spondyloarthopathies may Be Increased Due To Higher Prevalence Of Risk Factors As Well As The Disease Itself- A Retrospective Analysis At Single VA Medical Center
Trayton Mains¹ and Vikas Majithia², ¹University of Mississippi Medical Center, Jackson, MS, ²G.V. "Sonny" Montogomery VA Medical Center, Jackson, MS
Background/Purpose: An increased prevalence of cardiovascular disease (CVD) and coronary heart disease (CHD) has been reported in patients with spondyloarthritides (SpA). This study investigated the…
Abstract Number: 1799 • 2013 ACR/ARHP Annual Meeting
Effect Of Certolizumab Pegol Over 48 Weeks In Patients With Axial Spondyloarthritis, Including Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis
Robert B. M. Landewé¹, Martin Rudwaleit², Désirée M. van der Heijde³, Maxime Dougados⁴, Philip Mease⁵, John D. Reveille⁶, Jessica Walsh⁷, Alan J. Kivitz⁸, Walter P. Maksymowych⁹, Jürgen Braun¹⁰, Atul A. Deodhar¹¹, Christian Stach¹², Bengt Hoepken¹², Pritibha Singh¹² and Joachim Sieper¹³, ¹Academic Medical Center/University of Amsterdam & Atrium Medical Center, Amsterdam, Netherlands, ²Endokrinologikum Berlin, Berlin, Germany, ³Dept of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Rheumatology B Department, Paris-Descartes University, APHP, Cochin Hospital, Paris, France, ⁵Division of Rheumatology Research, Swedish Medical Center and University of Washington, Seattle, WA, ⁶Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, ⁷Rheumatology, University of Utah Hospital, Salt Lake City, UT, ⁸Altoona Center for Clinical Research, Duncansville, PA, ⁹Medicine, University of Alberta, Edmonton, AB, Canada, ¹⁰Rheumazentrum Ruhrgebiet, Herne, Germany, ¹¹Div of Arthritis & Rheum OP-09, Oregon Health & Science University, Portland, OR, ¹²UCB Pharma, Monheim, Germany, ¹³Rheumatology, Charité Universitätesmedizin Berlin, Berlin, Germany
Background/Purpose: Previous reports of RAPID-axSpA have demonstrated the efficacy and safety of certolizumab pegol (CZP), a PEGylated Fc-free anti-TNF, in patients (pts) with axial spondyloarthritis…
Abstract Number: 1505 • 2013 ACR/ARHP Annual Meeting
Evaluation Of a Case Ascertainment Tool For Ankylosing Spondylitis and Axial Spondylarthritis Among All Referrals To General Rheumatology Clinics
Eswar Krishnan¹, Michael H. Weisman², Atul A. Deodhar³, Linjun Chen¹ and Lianne S. Gensler⁴, ¹Medicine, Stanford University, Palo Alto, CA, ²Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ³Div of Arthritis & Rheum OP-09, Oregon Health & Science University, Portland, OR, ⁴Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA
Background/Purpose: Several strategies for distinguishing Ankylosing Spondylitis (AS) and Axial Spondylarthritis (axSpA) from other conditions have been proposed but have only been studied in the…
Abstract Number: 1015 • 2013 ACR/ARHP Annual Meeting
Quality Of Life, Productivity Impairment, Disease Severity and Health Care Costs In Relation To Functional Impairment In Ankylosing Spondylitis Patients In The Czech Republic
Liliana Sedova^1,2, Jiri Stolfa^1,2, David Suchy³, Andrea Smrzova⁴, Jiri Klimes⁵, Milan Vocelka⁵ and Tomas Dolezal⁵, ¹Institute of Rheumatology, Prague, Czech Republic, ²Clinic of Rheumatology, Charles University Prague, Prague, Czech Republic, ³Department of Clinical Pharmacology, Rheumatology, University hospital Plzen, Plzen, Czech Republic, ⁴3rd internal clinic, University hospital Olomouc, Olomouc, Czech Republic, ⁵Institute of Health Economics and Technology Assessment, Charles University, Prague, Czech Republic
Background/Purpose: Our aim was to describe the quality-of-life (QoL), productivity impairment, clinical indicators and health care costs in relationship to functional status described by Bath…
Abstract Number: 2776 • 2013 ACR/ARHP Annual Meeting
Ankylosing Spondylitis Is Associated With An Increased Likelihood Of Cardiovascular Disease: A Nationwide Matched Cohort Study In Primary Care
Linda E. Dean¹, Gary J. Macfarlane¹, Alan G. MacDonald² and Gareth T. Jones¹, ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²Department of Rheumatology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom
Background/Purpose: Cardiovascular disease (CVD) risk is well established in rheumatoid arthritis but less so in ankylosing spondylitis (AS). Due to a similar inflammatory profile, AS…
Abstract Number: 2438 • 2013 ACR/ARHP Annual Meeting
Effectiveness Of Exercise Program in Ankylosing Spondylitis: Meta-Analysis Of Randomized Controlled Trials
Virginie Pécourneau¹, Arnaud L. Constantin² and Alain G. Cantagrel³, ¹CHU Toulouse, Toulouse, France, ²Rheumatology, Purpan University Hospital, Toulouse Cedex 9, France, ³Dept of Rheumatology, Hopital Purpan, Toulouse CEDEX 9, France
Effectiveness of exercise programs in ankylosing spondylitis: meta-analysis of randomized controlled trialsVirginie PÃ©courneau1, Adeline Ruyssen-Witrand1, Thomas Barnetche2, Alain Cantagrel1, Arnaud Constantin1.1 Centre de Rhumatologie, HÃxpital…
Abstract Number: 1802 • 2013 ACR/ARHP Annual Meeting
A Major Clinical Response To Anti-Tumor Necrosis Factor Agents Is Associated With a Reduced Development Of Fatty Changes In The Spine Of Patients With Ankylosing Spondylitis
Xenofon Baraliakos¹, Frank Heldmann², Joachim Listing³, Johanna Callhoff³ and Jürgen Braun², ¹Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, ²Rheumazentrum Ruhrgebiet, Herne, Germany, ³German Rheumatism Research Center, Berlin, Germany
Background/Purpose: Fatty changes (FC) on T1-weighted magnetic resonance images (MRI) have been described in the spine of patients with ankylosing spondylitis (AS). Such lesions were…
Abstract Number: 1506 • 2013 ACR/ARHP Annual Meeting
Total Hip Replacement Outcomes in Ankylosing Spondylitis
Susan M. Goodman¹, Rebecca Zhu², Wei-Ti Huang³, Mark P. Figgie⁴, Michael Alexiades⁵ and Lisa A. Mandl¹, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Clinical Research, Hospital for Special Surgery, New York, NY, ³Epidemiology and Statistics, Hospital for Special Surgery, New York, NY, ⁴Orthopedics, Hospital for Special Surgery, New York, NY, ⁵Orthopaedics, Hospital for Special Surgery, New York, NY
Background/Purpose: Historically, outcomes for total hip replacement (THR) in ankylosing spondylitis (AS) patients were poor, but contemporary outcomes are not well described. We analyzed two-year…
Abstract Number: 991 • 2013 ACR/ARHP Annual Meeting
Utilization Of An Informational Needs Assessment To Develop An Education Program For Patients With Ankylosing Spondylitis (AS) and Related Axial Spondyloarthritis (SpA)
Rita Kang¹, Rebecca Morton², Christopher Hawke³, Laura A. Passalent⁴, Robert D. Inman^5,6, Dinny Wallis⁷, Joan Blair³, Alison Lake⁸, Heather Sloman⁸, Marc Doucet⁹, Debra MacGarvie⁸ and King Wong⁹, ¹Patient Education, University Health Network- Toronto Western Hospital, Toronto, ON, Canada, ²Allied Health/Rheumatology, University Health Network- Toronto Western Hospital, Toronto, ON, Canada, ³Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ⁴Allied Health, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ⁵Dept of Medicine/Rheumatology, Toronto Western Research Institute, University Health Network and University of Toronto, Toronto, ON, Canada, ⁶U of Toronto, Toronto, ON, Canada, ⁷Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ⁸University Health Network- Toronto Western Hospital, Toronto, ON, Canada, ⁹University Health Network, Toronto, ON, Canada
Background/Purpose: The effectiveness of education programs for patients with arthritis has been well documented. Despite this, there has been minimal investigation into patient education specifically…
Abstract Number: 2697 • 2013 ACR/ARHP Annual Meeting
Identification Of Genetic and Epigenetic Alterations In Spondyloarthritis
Tibor A. Rauch¹, Beata Tryniszewska¹, Andras Vida¹, Timea Ocsko¹, Sandor Szanto², Holly L. Rosenzweig³, Matthew A. Brown⁴, Gethin P Thomas⁵, Katalin Mikecz¹ and Tibor T. Glant¹, ¹Orthopedic Surgery, Rush University Medical Center, Chicago, IL, ²Rheumatology, University of Debrecen, Debrecen, Hungary, ³Oregon Health & Science University, Portland, OR, ⁴Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, Australia, ⁵Translational Reserch Institute, University of Queensland Diamantina Institute, Woolloongabba, Australia
Background/Purpose: Ankylosing spondylitis (AS) is the prototypic spondyloarthritis and affects approximately 0.2-0.5% of the human population. It is estimated that genetic risk factors contribute >90%…
Abstract Number: 2440 • 2013 ACR/ARHP Annual Meeting
Is There a Role For Etoricoxib In Patients With Axial Ankylosing spondylitis Refractory To Traditional NSAID?
Maria García Manrique¹, Pilar Font², Joan Calvet³, María Cruz Fernandez⁴, Carlos Montilla⁵, Luis Linares⁶, Elia Brito⁷, Xavier Juanola⁸, Juan Mulero⁹, Rubén Queiro¹⁰, Rosa M. Morla¹¹, Rosario Garcia-Vicuña¹², Alba Erra¹³, Mireia Moreno¹⁴, Marta Larrosa¹⁵, Eduardo Collantes¹⁶ and Jordi Gratacos¹⁷, ¹Rheumatology, Hospital Parc Taulí, Sabadell, Spain, ²Rheumatology Unit, IMIBIC-Reina Sofia University Hospital, Cordoba, Spain, ³Rheumatology, Corporació Sanitària Parc Taulí, Sabadell, Spain, ⁴Rheumatology, Hospital General de Móstoles, Mostoles, Spain, ⁵Rheumatology Service, Hospital Universitario de Salamanca, Salamanca, Spain, ⁶Rheumatology, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain, ⁷Rheumatology, Hospital Ramón y Cajal, Madrid, Spain, ⁸Rheumatology, University Hospital Bellvitge, Barcelona, Spain, ⁹Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda (Madrid), Spain, ¹⁰Rheumatology Department. Hospital Universitario Central de Asturias, Oviedo, Spain, ¹¹Rheumatology, Hospital Sta Tecla, Tarragona, Spain, ¹²Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, ¹³Hospital de Sant Rafael, Barcelona, Spain, ¹⁴Rheumatology, Hospital Universitari Parc Taulí, Sabadell, Spain, ¹⁵Rheumatology, Hospital Universitari Parc Tauli, Sabadell, Spain, ¹⁶Rheumatology, Hospital Reina Sofia, Cordoba, Spain, ¹⁷Rheumatology Service, Hospital Universitari Parc Taulí, Sabadell (Barcelona), Spain
Background/Purpose: Anti-TNF treatment has demonstrated its effectiveness in axial ankylosing spondylitis (AS) patients with inadecuate response to traditional NSAIDs (tNSAIDs) therapy (>=2 tNSAIDs), but also aspects…
Abstract Number: 1706 • 2013 ACR/ARHP Annual Meeting
Fine-Mapping Major Histocompatibility Complex Variation Associated With Ankylosing Spondylitis Susceptibility
Adrian Cortes¹, International Genetics of Ankylosing Spondylitis Consortium (IGAS)², Paul de Bakker³ and Matthew A. Brown⁴, ¹Human Genetics Group, The University of Queensland Diamantina Insititute, Brisbane, Australia, ²University of Queensland Diamantina Institute, brisbane, Australia, ³Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands, ⁴University of Queensland Diamantina Institute, Brisbane, Australia
Background/Purpose: Ankylosing spondylitis (AS) is a common, highly heritable, inflammatory arthritis. Thus far, 27 susceptibility loci have been identified in and outside the MHC in…
Abstract Number: 1508 • 2013 ACR/ARHP Annual Meeting
How Well Are The Assessment Of Spondyloarthritis International Society (ASAS) / Outcome Measures In Rheumatology (OMERACT) Core Outcome Sets For Ankylosing Spondylitis Implemented In Randomized Clinical Trials? A Systematic Literature Review
Wilson Bautista-Molano^1,2, Victoria Navarro-Compán¹, Robert Landewé³ and Désirée van der Heijde⁴, ¹Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Department of Rheumatology, Universidad Militar Nueva Granada, Bogotá, Colombia, ³Rheumatology, Academic Medical Center, Amsterdam, Netherlands, ⁴Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The Assessment of SpondyloArthritis international Society (ASAS) has selected a core set of variables to include as standardized endpoints in clinical trials and clinical…
Abstract Number: 530 • 2013 ACR/ARHP Annual Meeting
Pattern Recognition Receptor Stimulated Cytokine Expression By Spondyloarthritis Patient Macrophages
Yi-Ping Liu¹, Ashley Bomkamp², Jens Eickhoff³, Jack Schneck², Mike Khan⁴ and Judith Smith⁵, ¹Department of Pediatrics, University of Wisconsin-Madison, Madison, WI, ²University of Wisconsin-Madison, Madison, WI, ³Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, ⁴Cellular and Molecular Pathology, University of Wisconsin-Madison, Madison, WI, ⁵Pediatrics, University of Wisconsin-Madison, Madison, WI
Background/Purpose: Spondyloarthritis (SpA) encompasses a group of chronic inflammatory conditions involving axial arthritis that includes ankylosing spondylitis (AS). GWAS studies in AS have implicated multiple…

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