Abstracts tagged "Ankylosing spondylitis (AS)"

Abstract Number: 1118 • 2013 ACR/ARHP Annual Meeting
Assessment Of Structural Damage In Patients With Ankylosing Spondylitis Using 18F-Fluoride Positron Emission Tomography-Magnetic Resonance Imaging
GeunTae Kim¹, Seung-Geun Lee², Seong-Ho Kim³, Joung-Wook Lee⁴ and Seung-Hoon Baek⁵, ¹Kosin University College of Medicine, Busan, South Korea, ²Divsion of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Pusan National University Hospital, Busan, South Korea, ³Internal Medicine, Division of Rheumatology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, South Korea, ⁴Divsion of Rheumatology, Department of Internal Medicine, Busan St. Mary’s Medical Center, Busan, South Korea, ⁵Divsion of Rheumatology, Department of Internal Medicine, Ilsin Christian Hospital, Busan, South Korea
Background/Purpose: 18F-fluoride uptake represents active osteoblastic bone synthesis. We explored structural damage of patients with ankylosing spondylitis (AS) using 18F-fluoride positron emission tomography (PET)-magnetic resonance…
Abstract Number: L15 • 2013 ACR/ARHP Annual Meeting
Efficacy and Safety of CT-P13 (Infliximab Biosimilar) over Two Years in Patients with Ankylosing Spondylitis: Comparison Between Continuing with CT-P13 and Switching from Infliximab to CT-P13
Won Park¹, Pedro Miranda², Marek Brzosko³, Piotr Wiland⁴, Sergio Gutierrez-Ureña⁵, Helena Mikazane⁶, Yeon-Ah Lee⁷, Svitlana Smiyan⁸, Mie-Jin Lim¹, Vladimir Kadinov⁹, Carlos Abud-Mendoza¹⁰, YoungKi Son¹¹, Dae-Hyun Yoo¹² and Jürgen Braun¹³, ¹Division of Rheumatology, Department of Internal Medicine, Inha University Hospital, Incheon, South Korea, ²Universidad de Chile and Centro de Estudios Reumatologicos, Santiago de Chile, Chile, ³Department of Rheumatology and Internal Diseases, Department of Rheumatology and Internal Diseases Pomeranian Medical University in Szczecin, Szczecin, Poland, ⁴Department of Rheumatology, Medical University of Wroclaw, Wroclaw, Poland, ⁵Antiguo Hospital Civil de Guadalajara, Guadalajara, Mexico, ⁶Outpatient Clinic 'ORTO', Riga, Latvia, ⁷Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Seoul, South Korea, ⁸Municipal Institution of Ternopil Regional Council "Ternopil University Hospital", Ternopil, Ukraine, ⁹Multiprofile Hospital for Active Treatment 'Sv. Marina', Varna, Bulgaria, ¹⁰Hospital Central Dr. Ignacio Morones Prieto, San Luis Potosyi, Mexico, ¹¹CELLTRION, Incheon, South Korea, ¹²Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ¹³PsAID taskforce, EULAR, Zurich, Switzerland
Background/Purpose: CT-P13 is an infliximab (INX) biosimilar recently approved by the European Medicine Agency. PLANETAS was a 54-week (wk) randomized double-blind parallel group multicenter Phase…
Abstract Number: 2888 • 2013 ACR/ARHP Annual Meeting
Frequent Detection Of Inflammation and Fat Infiltration Suggestive Of Spondyloarthritis On MRI Of The Entire Spine In Healthy Subjects and Patients With Mechanical Back Pain
Ulrich Weber¹, Zheng Zhao², Veronika Zubler³, Stanley Chan⁴, Robert GW Lambert⁵, Mikkel Ostergaard⁶, Susanne Juhl Pedersen⁷, Kaspar Rufibach⁸ and Walter P. Maksymowych⁹, ¹Rheumatology, Balgrist University Hospital, Zurich, Switzerland, ²Department of Rheumatology, University of Alberta and PLA General Hospital, Beijing, PR China, Beijing, AB, China, ³Radiology, Balgrist University Hospital, Zurich, Switzerland, ⁴Division of Ophthalmology, University of Alberta, Edmonton, AB, Canada, ⁵Radiology, University of Alberta, Edmonton, AB, Canada, ⁶Copenhagen Center for Arthritis Research, Glostrup, Denmark, ⁷Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, ⁸rePROstat, Basel, Switzerland, ⁹Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Mechanical back pain (MBP) patients and healthy subjects may show spinal MRI lesions suggestive for spondyloarthritis (SpA) such as corner inflammatory lesions (CIL) or…
Abstract Number: 2456 • 2013 ACR/ARHP Annual Meeting
Prevalence Of Overweight and Obesity and The Relation To Disease Activity, Physical Function and Quality Of Life In Patients With Axial Spondyloarthritis
Fiona Maas¹, Anneke Spoorenberg¹, Eveline van der Veer², Reinhard Bos³, Monique Efde³, Hendrika Bootsma⁴, Elisabeth Brouwer⁵ and Suzanne Arends^3,4, ¹Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands, ²Laboratory Medicine, University Medical Center Groningen, Groningen, Netherlands, ³Rheumatology, Medical Center Leeuwarden, Leeuwarden, Netherlands, ⁴Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ⁵Dept. of Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands
Background/Purpose: Obesity is a growing problem in Western society. It is associated with an increased risk for many disorders, impaired functional capacity, and impaired quality…
Abstract Number: 2042 • 2013 ACR/ARHP Annual Meeting
Pregnancy Outcomes In Women With Rheumatologic Conditions Exposed To Infliximab
Sirisha Kalari¹, Fredrik Granath², Chun-Yuan Guo¹, Diane D. Harrison¹, Gabriella Bröms², Anja Geldhof³, Riikka Nissinen³, Marilyn Sanders¹, Mika Gissler⁴, Lars Pedersen⁵, Henrik Toft Sorensen⁵ and Helle Kieler², ¹Janssen Research & Development, LLC., Horsham, PA, ²Centre for Pharmacoepidemiology, Karolinska Institutet, Stockholm, Sweden, ³Janssen Biologics Europe, Leiden, Netherlands, ⁴Information Department, National Institute for Health and Welfare, Helsinki, Finland, ⁵Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
Background/Purpose: RA, AS, and PsA are approved indications for infliximab (IFX). In the US, IFX is a pregnancy Category B drug. For RA and some…
Abstract Number: 1526 • 2013 ACR/ARHP Annual Meeting
Stable Clinical and MRI Response In Patients With Early Axial Spondyloarthritis After 3 Years Of Continuous Treatment With Etanercept, Data Of The Esther Trial
In-Ho Song¹, Kay-Geert A. Hermann², Hildrun Haibel¹, Christian Althoff³, Denis Poddubnyy⁴, Joachim Listing⁵, Anja Weiss⁶, Ekkehard Lange⁷, Bruce Freundlich⁸, Martin Rudwaleit⁹ and Joachim Sieper⁴, ¹Medical Department I, Rheumatology, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany, ²Radiology, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, ³Radiology, Charite Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, ⁴Charité Universitätsmedizin Berlin, Berlin, Germany, ⁵German Rheumatism Research Center, Berlin, Germany, ⁶German Rheumatism Research Centre, Berlin, Germany, ⁷BU Specialty Care, Pfizer Pharma AG, Berlin, Germany, ⁸University of Pennsylvania, Philadelphia, PA, ⁹Endokrinologikum, Berlin, Germany
Background/Purpose: < style="text-align: justify;">In patients with early axial spondyloarthritis (SpA) with a disease duration of 10 years) where BASDAI50 response rates of 47%…
Abstract Number: 1119 • 2013 ACR/ARHP Annual Meeting
Quantification Of Inflammatory Disease Of Spine In Ankylosing Spondylitis Using Volumetric Magnetic Resonance Imaging Analysis
Ejaz Pathan¹, Adrian Lim², Andy Graham³, Keshthra Satchithananda², Dobrina Hull⁴, Sonya Abraham⁵, Anshul Rastogi⁶, Andrew Keat⁷, Mark Hinton⁸, Olga Kubassova⁹, Peter C. Taylor¹⁰ and J.V. Hajnal¹¹, ¹Clinical Trials Unit, Kennedy Institute of Rheumatology, London W6 8RF, United Kingdom, ²Radiology, Imperial College Healthcare NHS Trust, London, United Kingdom, ³QABC Minster House, Image Analysis, London, United Kingdom, ⁴Clinical Trials Unit, The Kennedy Institute of Rheumatology, London, United Kingdom, ⁵Rheumatology, Charing Cross Hospital, Imperial college NHS trust London UK, London W6 8RF, United Kingdom, ⁶Radiology, Barts and the London NHS Trust, London, United Kingdom, ⁷Rheumatology, Northwick Park Hospital, Harrow, United Kingdom, ⁸Image Analysis Ltd, London, United Kingdom, ⁹Image Analysis Ltd., Leeds, United Kingdom, ¹⁰NDORMS, Botnar Research Centre, University of Oxford, Oxford, United Kingdom, ¹¹Division of Imaging Sciences, King's College London, London, United Kingdom
Background/Purpose: To develop methodology for quantification of spinal inflammation in AS using a volumetric MRI-based technique and to explore relationships between these findings and clinical measures…
Abstract Number: 2838 • 2013 ACR/ARHP Annual Meeting
Relationship Between Active Inflammatory Lesions In The Spine and Sacroiliac Joints and Development Of Fatty Lesions On Whole-Body MRI In Patients With Early Axial Spondyloarthritis- Long-Term Data Of The Esther Trial
In-Ho Song¹, Kay-Geert A. Hermann², Hildrun Haibel³, Christian Althoff⁴, Denis Poddubnyy³, Joachim Listing⁵, Anja Weiss⁶, Ekkehard Lange⁷, Bruce Freundlich⁸, Martin Rudwaleit⁹ and Joachim Sieper¹⁰, ¹Medical Department I, Rheumatology, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany, ²Radiology, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, ³Charité Universitätsmedizin Berlin, Berlin, Germany, ⁴Radiology, Charite Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, ⁵German Rheumatism Research Center, Berlin, Germany, ⁶German Rheumatism Research Centre, Berlin, Germany, ⁷BU Specialty Care, Pfizer Pharma AG, Berlin, Germany, ⁸University of Pennsylvania, Philadelphia, PA, ⁹Endokrinologikum, Berlin, Germany, ¹⁰Medical Department I, Rheumatology, Charité Universitätsmedizin Berlin, Campus Benjamin-Franklin, Berlin, Germany
Background/Purpose : In patients with early axial spondyloarthritis (SpA) with evidence of active inflammation on magnetic resonance imaging (MRI) in the spine and/or sacroiliac (SI-)joints…
Abstract Number: 2458 • 2013 ACR/ARHP Annual Meeting
Change Over Time In The Profile Of Ankylosing Spondylitis Patients Treated With Infliximab In Canadian Routine Care
Denis Choquette¹, Michael Starr², Majed M. Khraishi³, William G. Bensen⁴, Saeed A. Shaikh⁵, Jude F. Rodrigues⁶, Dalton E. Sholter⁷, Maqbool K. Sheriff⁸, Julie Vaillancourt⁹, John S. Sampalis⁹, Allen J. Lehman¹⁰, Susan M. Otawa¹⁰, Francois Nantel¹¹ and May Shawi¹², ¹Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, ²Montreal General Hospital, Montreal, QC, Canada, ³Nexus Clinical Research, St John's, NF, Canada, ⁴Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada, ⁵Medicine, McMaster University, St Catharines, ON, Canada, ⁶Rheumatology, Windsor, ON, Canada, ⁷Rheumatology Associates, Edmonton, AB, Canada, ⁸Nanaimo Regional General Hospital, Nanaimo, BC, Canada, ⁹JSS Medical Research, Montreal, QC, Canada, ¹⁰Medical Affairs, Janssen Inc., Toronto, ON, Canada, ¹¹Janssen Inc., Toronto, ON, Canada, ¹²Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada
Background/Purpose: Canadian provincial reimbursement policies in regards with infliximab coverage status have evolved in the last decade. The objective of this study was to describe…
Abstract Number: 1901 • 2013 ACR/ARHP Annual Meeting
Genetic Variants In OPG and ANKH Are Associated With Severity Ofankylosis In Ankylosing Spondylitis In a Korean Cohort
Il-Hoon Sung¹, Tae-Hwan Kim², Young Bin Joo³, So-Young Bang⁴, Seunghun Lee⁵, Kyung-Bin Joo⁶, Proton Rahman⁷, Darren D. O'Rielly⁷ and Robert Inman⁸, ¹Orthopaedic surgery, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ²Division of Rheumatology, Department of Internal Medicine, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ³Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ⁴Hanyang University Guri Hospital, Guri, South Korea, ⁵Department of Radiology, Department of Radiology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ⁶Department of Radiology, Department of Radiology, Hanynag University Hospital for Rheumatic Diseases, Seoul, South Korea, ⁷Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ⁸Immunlogy and Institute of Medical Science, University of Toronto and Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Spinal ankylosis,which represents the most severe radiologic change in ankylosing spondylitis (AS),is associated with permanent work disability as well as decreased quality of life.…
Abstract Number: 1527 • 2013 ACR/ARHP Annual Meeting
Routine Assessment Of Patient Index Data 3 Scores Correlate Well With Bath Ankylosing Spondylitis Disease Activity Index In The Assessment Of Disease Activity and Monitoring Progression Of Ankylosing Spondylitis
Abhijeet Danve¹, Kiana Vakil-Gilani², Anusha Reddy², Annan Sheffield³, Alexis Dinno⁴ and Atul A. Deodhar⁵, ¹Rheumatology, Oregon Health and Science University, Portland, OR, ²Arthritis and Rheumatic diseases, Oregon Health and Science University, Portland, OR, ³Portland State University, Portland, OR, ⁴School of Community Health, Portland State University, Portland, OR, ⁵Oregon Health and Science University, Portland, OR
Background/Purpose: Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) is a composite tool unique to measure disease activity in ankylosing spondylitis (AS) just as Disease Activity…
Abstract Number: 1126 • 2013 ACR/ARHP Annual Meeting
Opportunistic Computed Tomography Screening For Determining Osteoporosis In Patients With Ankylosing Spondylitis and Spine Fractures
Amanda Cagan¹, Osa Emohare¹, Robert Morgan¹, David Polly² and Elie Gertner³, ¹Spine and Spinal Cord Injury, Regions Hospital, Saint Paul, MN, ²Division of Orthopedics, University of Minnesota, Minneapolis, MN, ³Section of Rheumatology, Regions Hospital and University of Minnesota Medical School, St. Paul, MN
Background/Purpose: In advanced disease Ankylosing Spondylitis (AS) is frequently associated with a reduction in bone mineral density (BMD) which contributes to pain and predisposes to…
Abstract Number: 2840 • 2013 ACR/ARHP Annual Meeting
Predictors Of Spinal Mobility Progression In A Multi-ethnic Cohort Of Patients With Ankylosing Spondylitis
Roozbeh Sharif¹, Trisha M. Parekh², Lianne S. Gensler³, MinJae Lee⁴, Mohammad Rahbar⁵, Laura A. Diekman⁶, Michael H. Weisman⁷, Michael M. Ward⁸, Shervin Assassi⁹ and John D. Reveille⁹, ¹Graduate School of Biomedical Science, University of Texas Medical Branch, Galveston, TX, ²Internal Medicine, University of Texas Medical Branch, Galveston, TX, ³Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁴Biostatistics/Epidemiology/Research Design (BERD) Core | Center for Clinical and Translational Sciences, University of Texas Health Science Center at Houston, Houston, TX, ⁵The University of Texas Health Science Center at Houston, Houston, TX, ⁶Rheumatology, The University of Texas Health Science Center at Houston, Houston, TX, ⁷Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁸Bldg 10 CRC Rm 4-1339, NIAMS/NIH, Bethesda, MD, ⁹Rheumatology, University of Texas Health Science Center at Houston, Houston, TX
Background/Purpose: Clinicians utilize several different clinical measurements (metrology) in patients with Ankylosing Spondylitis (AS) to assess the spinal mobility. We aimed to examine the pattern…
Abstract Number: 2460 • 2013 ACR/ARHP Annual Meeting
Spondyloarthritis Epidemiology and Burden Phase 2 [SPEED 2] Study: Disease Progression In Axial Spondyloarthropathy (SpA)
Eric Ruderman¹, Vibeke Strand², Avani Joshi³, Yanjun Bao³, Keith Betts⁴, Pooja Chopra⁴, Michael B. McGuire⁵ and Sumati A Rao³, ¹Northwestern University, Chicago, IL, ²Stanford University, Palo Alto, CA, ³AbbVie Inc., North Chicago, IL, ⁴Analysis Group, Inc., Boston, MA, ⁵Medical Data Analytics, Parsippany, NJ
Background/Purpose: Limited information is available on progression of non-radiographic axial spondyloarthropathy (nr-axSpA) to ankylosing spondylitis (AS) in patients with SpA meeting the Assessment of Spondyloarthritis…
Abstract Number: 1821 • 2013 ACR/ARHP Annual Meeting
Benefits Of Progressive Muscle Strengthening Using a Swiss Ball In Patients With Ankylosing Spondylitis: A Randomized Controlled Trial
Marcelo Souza¹, Fabio Jennings², Hisa Morimoto¹ and Jamil Natour³, ¹Division of Rheumatology, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ²Rheumatology Division, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ³Rheumatology, Universidade Federal de São Paulo, São Paulo, Brazil
Background/Purpose: Ankylosing spondylitis (AS) is a systemic inflammatory disease that affects the physical capacity of patients globally. Exercises are recommended to the management of patients…

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