Abstracts tagged "Ankylosing spondylitis (AS)"

Abstract Number: 2336 • 2015 ACR/ARHP Annual Meeting
Literature Review of Patient Reported Outcome and Health Related Quality of Life Measures for Biologic Therapies in the Management of Psoriatic Arthritis and Ankylosing Spondylitis
Steffen Jugl¹, Sultana Syeda² and Gunda Praveen², ¹BF I&D GPA, Health Economics and Outcomes Research, Novartis Pharma AG, Basel, Switzerland, ²Novartis Healthcare Pvt. Ltd., Hyderabad, India, Hyderabad, India
Background/Purpose: Psoriatic arthritis (PsA) and ankylosing spondylitis (AS) are chronic progressive conditions with substantial humanistic burden on patients and care givers. A variety of instruments,…
Abstract Number: 3207 • 2015 ACR/ARHP Annual Meeting
Axial Disease in Psoriatic Arthritis: A Clinical and Radiographic Comparison with Ankylosing Spondylitis
Deepak R. Jadon¹, Raj Sengupta¹, Alison L Nightingale², Mark Lindsay³, Eleanor Korendowych¹, Graham Robinson⁴, Amelia Jobling⁵, Gavin Shaddick⁶, Anne Barton⁷ and Neil J. McHugh⁸, ¹Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, ²Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom, ³Pharmacy & Pharmacology, University of Bath, Bath, United Kingdom, ⁴Royal United Hospital, Bath, United Kingdom, ⁵Mathematical Sciences, University of Bath, Bath, United Kingdom, ⁶Department of Mathematics, University of Bath, Bath, United Kingdom, ⁷Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University Of Manchester, Manchester, United Kingdom, ⁸Rheumatology, Royal National Hospital for Rheumatic Diseases, Upper Borough Walls, United Kingdom
Background/Purpose: Little is known of the characteristics of psoriatic spondyloarthritis (PsSpA). A study was conducted to determine the: (i) prevalence of PsSpA in a psoriatic…
Abstract Number: 696 • 2015 ACR/ARHP Annual Meeting
Current and Past Smoking Are Associated with Functional Impairement and Increased Disease Activity in Axial Spondyloarthritis: Systematic Review and Meta-Analysis
Kristina SCHREIBER¹, Thomas Barnetche², BG Combe³, Jacques Morel¹ and Claire I. Daien¹, ¹Department of rheumatology, Lapeyronie Hospital and Montpellier University, Montpellier, France, ²Rheumatology Department, Pellegrin University Hospital, BORDEAUX, France, ³Lapeyronie, Montpellier, France
Background/Purpose: The influence of smoking on the development of rheumatoid arthritis, the severity of the disease and the response to treatment is well established. The…
Abstract Number: 1701 • 2015 ACR/ARHP Annual Meeting
Long Term Outcome of Total Hip Replacement in Patients with Ankylosing Spondylitis
Ana Lizarraga¹, Natalia Zamora¹, Graciela Betancur¹, Luis Alejandro Cayetti², Emilce Schneeberger², Maria Celeste Orozco³, Fernando Andres Sommerfleck⁴ and Gustavo Citera³, ¹Reumatologia, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ²Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ³Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ⁴Rheumatologia, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina
Background/Purpose: Total hip replacement (THR) surgery is a reliable therapeutic intervention for patients with severe hip involvement. The aim of our study was to determine…
Abstract Number: 2647 • 2015 ACR/ARHP Annual Meeting
Correlations Between Personality Types, Disease Activity and Quality of Life in As and RA Patients
Teodora Donisan¹, Madalina Dobrin², Denisa Predeteanu^3,4, Violeta Claudia Bojinca^4,5, Mihai Bojinca^6,7, Dinu Valentin Balanescu¹, Laura Grosanu^3,5, Florian Berghea^4,5, Cosmin Constantinescu^4,5, Daniela Opris^3,4, Andreea Borangiu^3,8, Ruxandra Ionescu^3,4 and Andra Rodica Balanescu^4,5, ¹University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania, ²Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, ³University of Medicine and Pharmacy “Carol Davila”, Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, ⁴Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, ⁵Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania, ⁶Department of Internal Medicine and Rheumatology “Dr. I. Cantacuzino” Hospital, University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania, ⁷Department of Internal Medicine and Rheumatology “Dr. I. Cantacuzino” Hospital, Bucharest, Romania, ⁸University of Medicine and Pharmacy “Carol Davila”, Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Romania, Bucharest, Romania
Background/Purpose: It is well established that health related quality of life (HRQoL) is low in patients (pts) with RA and AS. Type C and D…
Abstract Number: 3211 • 2015 ACR/ARHP Annual Meeting
Current Smoking, Its Intensity and Duration, Is Associated with Fat Metaplasia on MRI in Patients with Spondyloarthritis
Walter Maksymowych¹, Stephanie Wichuk¹, Praveena Chiowchanwisawakit², Zheng Zhao³, Donald Spady¹, Barbara Conner-Spady¹, Robert G Lambert⁴ and Susanne Juhl Pedersen⁵, ¹Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, ²Rheumatology, Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand, ³Rheumatology, Chinese PLA General Hospital, Beijing, China, ⁴Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁵Copenhagen Center for Arthritis Research, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Smoking has been associated with radiographic severity and progression in SpA although there is little understanding of the mechanism. Prospective MRI data indicates…
Abstract Number: 699 • 2015 ACR/ARHP Annual Meeting
Improving Ankylosing Spondylitis Specific Outcomes at 6 Months Utilising a Novel Self-Management Education Program
Charles Inderjeeth^1,2,3,4, Jean McQuade⁵, Warren Raymond⁶, Clara Connor⁷, Jack Edelman⁸, Nicola Cook⁹ and Kathy Briffa¹⁰, ¹Rehabiltation and Aged care and Rheumatology, Sir Charles Gairdner Hospital and University of Western Australia, Nedlands, Australia, ²North Metropolitan Health Service, University of Western Australia, Perth, WA, Australia, ³Subiaco Rheumatology Clinic, Subiaco, Australia, ⁴Linear Clinical Research Ltd, Perth, Australia, ⁵Arthritis WA, Wembley, Australia, ⁶Rheumatology and Geriatric Medicine, Sir Charles Gairdner Hospital and University of Western Australia, Nedlands, Australia, ⁷Arthritis and Osteoporosis WA, Perth, Australia, ⁸Rheumatology, Sir Charles Gairdner Hospital, Perth, Australia, ⁹Royal Perth Hospital, Perth, Australia, ¹⁰School of Physiotherapy and Exercise Science, Curtin University, Perth, Australia
Background/Purpose : Disease specific self-management interventions are rare. After a needs assessment, focus group discussions, and Plan, Do, Study, Act (PDSA) model we developed and…
Abstract Number: 1708 • 2015 ACR/ARHP Annual Meeting
Predictors of Depression Severity in Ankylosing Spondylitis
Mark Hwang¹, MinJae Lee², Michael M. Ward³, Lianne S. Gensler⁴, Matthew A. Brown⁵, Shervin Assassi⁶, Laura A. Diekman⁷, Mohammad H. Rahbar⁸, Michael H. Weisman⁹ and John D. Reveille¹⁰, ¹Internal Medicine, University of Texas Health Science Center at Houston, Houston, TX, ²Biostatistics/Epidemiology/Research Design (BERD) Core | Center for Clinical and Translational Sciences, University of Texas Health Science Center at Houston, Houston, TX, ³NIH/NIAMS, Bethesda, MD, ⁴Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁵The University of Queensland Diamantina Institute, Brisbane, Australia, ⁶Rheumatology, University of Texas Medical School at Houston, Houston, TX, ⁷Rheumatology, University of Texas Medical School, Houston, TX, ⁸The University of Texas Health Science Center at Houston, Houston, TX, ⁹Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ¹⁰Rheumatology, University of Texas Health Science Center at Houston, Houston, TX
Background/Purpose: Depression is a known comorbidity of ankylosing spondylitis (AS) with over one-third of AS patients affected and increased depression-rate ratio compared to the general…
Abstract Number: 2780 • 2015 ACR/ARHP Annual Meeting
Relationship Between Immunogenicity, Hypersensitivity Reactions and Skin Tests Against Infliximab, Etanercept and Adalimumab in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis
Firas Doghanji¹, Sebnem Ataman², Ali Erhan Ozdemirel², Recep Bülent Seckin¹, Ayse Peyman Yalcin¹ and Sevim Bavbek³, ¹Physical Medicine and Rehabilitation, Ankara University Faculty of Medicine, Ankara, Turkey, ²Rheumatology Department, Ankara University Faculty of Medicine, Ankara, Turkey, ³Immunology and Allergy, Ankara University Faculty of Medicine, Ankara, Turkey
Relationship between immunogenicity, hypersensitivity reactions and skin tests against Infliximab, Etanercept and Adalimumab in patients with rheumatoid arthritis and ankylosing spondylitis Background/Purpose: Anti-TNF drugs can…
Abstract Number: 709 • 2015 ACR/ARHP Annual Meeting
Progression of Patients with Non-Radiographic Axial Spondyloarthritis to Ankylosing Spondylitis: A Population-Based Cohort Study
Runsheng Wang¹, Sherine Gabriel² and Michael M. Ward¹, ¹NIH/NIAMS, Bethesda, MD, ²Division of Rheumatology; Department of Health Sciences Research, Mayo Clinic, Rochester, MN
Background/Purpose: The long-term outcome of patients with non-radiographic axial spondyloarthritis (nr-axSpA) is unclear, particularly whether few or most progress to ankylosing spondylitis (AS). Our objective…
Abstract Number: 1721 • 2015 ACR/ARHP Annual Meeting
Factors Predictive of Radiographic Progression in Ankylosing Spondylitis
Ismail Sari¹, Jonathan Chan², Ahmed Omar¹, Mohamed Bedaiwi¹, Renise Ayearst¹, Robert D Inman³ and Nigil Haroon¹, ¹Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ²Rheumatology, Spondylitis program, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ³Immunlogy and Institute of Medical Science, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada
Background/Purpose: Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the axial skeleton. New bone formation resulting in syndesmophytes can lead to spinal…
Abstract Number: 2804 • 2015 ACR/ARHP Annual Meeting
The Global miRNA Whole Blood Profile of Ankylosing Spondylitis
Carolina Mejia Otero¹, Shervin Assassi¹, Michael H. Weisman², Michael M. Ward³, Lianne S. Gensler⁴, Matthew A. Brown⁵, Minghua Wu¹, John Hagan⁶, John D. Reveille⁷ and Gloria Salazar¹, ¹Rheumatology, University of Texas Medical School at Houston, Houston, TX, ²Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ³NIH/NIAMS, Bethesda, MD, ⁴Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁵The University of Queensland Diamantina Institute, Brisbane, Australia, ⁶Neurosurgery, University of Texas at Houston, Houston, TX, ⁷Internal Medicine/Rheumatology, University of Texas Medical School at Houston, Houston, TX
Background/Purpose: MicroRNA (miRNA) are small non-coding RNAs that play an important role in posttranscriptional gene regulation and their involvement in the pathophysiology of several autoimmune…
Abstract Number: 2618 • 2014 ACR/ARHP Annual Meeting
Impact of Ustekinumab on Active Inflammation and Post-Inflammatory Structural Changes As Detected By Magnetic Resonance Imaging in Patients with Active Ankylosing Spondylitis: Results of a 28-Week, Prospective, Open-Label, Proof-of-Concept Study
Denis Poddubnyy¹, Kay-Geert Hermann¹, Johanna Callhoff², Joachim Listing² and Joachim Sieper¹, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²German Rheumatism Research Center, Berlin, Germany
Background/Purpose Ustekinumab – a fully human monoclonal antibody against interleukins 12 and 23 – has been shown to be effective in reduction of symptoms of…
Abstract Number: 2561 • 2014 ACR/ARHP Annual Meeting
Low Cardio-Respiratory Fitness Is Associated with Increased Arterial Stiffness in Patients with Ankylosing Spondylitis
Inger Jorid Berg¹, Anne Grete Semb², Silje H. Sveaas^3,4, Camilla Fongen³, Désirée van der Heijde^3,5, Tore K. Kvien³, Hanne Dagfinrud³ and Sella A. Provan³, ¹Dep of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴Health Sience, University of Oslo, Oslo, Norway, ⁵Leiden University Medical Center, Leiden, Netherlands
Background/Purpose We have previously shown that patients with ankylosing spondylitis (AS) have lower cardio-respiratory fitness (CRF) than population controls. CRF is inversely associated to risk…
Abstract Number: 1159 • 2014 ACR/ARHP Annual Meeting
Long-Term Quality of Life, Productivity Impairment, Disease Severity and Health Care Costs in Relation to Functional Impairment in Ankylosing Spondylitis Patients in the Czech Republic
Liliana Sedova^1,2, Monika Urbanova³, Jiri Stolfa^2,3, David Suchy⁴, Andrea Smrzova⁵, Tomas Mlcoch⁶, Jiri Klimes⁷ and Tomas Dolezal⁷, ¹rheumatology, Institute of Rheumatology, Prague, Czech Republic, ²Clinic of Rheumatology, Charles University Prague, Prague, Czech Republic, ³Inpatients´ Clinic, Institute of Rheumatology Prague, Prague, Czech Republic, ⁴Department of Clinical Pharmacology, Rheumatology, University hospital Plzen, Plzen, Czech Republic, ⁵3rd internal clinic, University hospital Olomouc, Olomouc, Czech Republic, ⁶Institute of Health Economics and Technology Assessment, Prague, Dominica, ⁷Institute of Health Economics and Technology Assessment, Charles University, Prague, Czech Republic
Background/Purpose To describe the quality-of-life (QoL), productivity impairment, clinical indicators and health care costs in relationship to functional status described by Bath Ankylosing Spondylitis Functional…

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