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Abstracts tagged "Ankylosing spondylitis (AS)"

  • Abstract Number: 2209 • 2019 ACR/ARP Annual Meeting

    Study of Vertebral Fracture Prevalence and Scanographic Bone Attenuation Coefficient of the First Lumbar Vertebra (SBAC-L1) in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis vs. Controls

    Marine Fauny1, Eliane Albuisson 2, Elodie Bauer 1, Julia Perrier-Cornet 1, Isabelle Chary-Valckenaere 2 and Damien Loeuille 3, 1CHRU Nancy, VANDOEUVRE, France, 2Centre Hospitalier Universitaire de Nancy, VANDOEUVRE, France, 3Rheumatology, Nancy University Hospital and and UMR 7365 CNRS-UL IMoPA, Université de Lorraine, VANDOEUVRE, France

    Background/Purpose: Osteoporosis is a common disease whose prognosis can be seriously impacted by the development of fractures that lead to functional limitations and may even…
  • Abstract Number: 570 • 2019 ACR/ARP Annual Meeting

    Pattern and Influential Factors in Promoting Treat-to-Target (T2T) for Follow-up of Ankylosing Spondylitis (AS) Patients with a Rheumatologist-patient Interactive Smart System of Disease Management (SSDM): A Cohort Study from China

    Jing Xue1, Hui Song 2, Hongzhi Wang 3, Jianlin Huang 4, Wenqiang Fan 5, Hua Wei 6, Hongbin Li 7, Weili Liu 8, Jin Zhang 9, Henglian Wu 10, Bei Wang 11, Jianhua Xu 12, Yan Huang 13, Hongjun Zhao 14, Zhiguo Wang 15, Zhiyong Huang 16, Xiaohong He 17, Wenhui Huang 18, Qiwen Ma 19, Bing Wu 20, Yuhua Jia 21, Yuan Liu 22, Hui Xiao 22, Fei Xiao 23 and Huaxiang Wu 1, 1The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China (People's Republic), 2Beijing Jishuitan Hospital, Beijing, Beijing, China (People's Republic), 3JiaXing First Hospital, Jiaxing, Zhejiang, China (People's Republic), 4The sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China (People's Republic), 5Central Hospital of XinXiang, Xinxiang, Hainan, China (People's Republic), 6Northern Jiangsu People's Hospital, Yangzhou, China (People's Republic), 7The Affiliated Hospital of Inner Mongolia Medical University, Huhehaote, Nei Mongol, China (People's Republic), 8Ningbo Medical Center Lihuili Hospital, Ningbo, Zhejiang, China (People's Republic), 9[email protected], Ningbo, Zhejiang, China (People's Republic), 10Dongguan donghua hospital, Dongguan, Guangdong, China (People's Republic), 11Beijing Hospital of Traditional Chinese Medicine, Beijing, Beijing, China (People's Republic), 12First Affiliated Hospital of Medical University Of Anhui, Hefei, Anhui, China (People's Republic), 13North China University of Science and Technology Affiliated Hospital, Tangshan, Hebei, China (People's Republic), 14The First Xiangya Hospital of Central South University, Changsha, Hunan, China (People's Republic), 15Tangshan Gongren Hospital, Tangshan, Hebei, China (People's Republic), 16Huizhou First Hospital, Huizhou, Guangdong, China (People's Republic), 17Guangdong Province Traditional Chinese Medical Hospital, Guangzhou, Guangdong, China (People's Republic), 18The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China (People's Republic), 19The First People's Hospital of Foshan, Foshan, Guangdong, China (People's Republic), 20Shanghai Gothic Internet Technology Co., Ltd, Shanghai, China (People's Republic), 21Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), 22Shanghai Gothic Internet Technology Co., Ltd, Shanghai, Shanghai, China (People's Republic), 23Shanghai Gothic Internet Technology Co., Ltd., shanghai, China (People's Republic)

    Background/Purpose: Ankylosing Spondylitis Disease Activity Score (ASDAS) is adopted to evaluate the degree of disease activity and the inflammatory response in AS patients. ASDAS score ≤…
  • Abstract Number: 619 • 2019 ACR/ARP Annual Meeting

    Relation of Therapies for Ankylosing Spondylitis to Risk of Total Hip and Knee Arthroplasty

    Rachael Stovall1, Christine Peloquin 2, David Felson 3, Tuhina Neogi 2 and Maureen Dubreuil 4, 1Boston Medical Center, Boston, MA, 2Boston University School of Medicine, Boston, MA, 3Boston University School of Medicine, Department of Rheumatology, Boston, 4Boston University School of Medicine, Boston

    Background/Purpose: Ankylosing spondylitis (AS) is an inflammatory arthritis that predominantly affects the axial skeleton, but commonly affects peripheral joints as well. Peripheral joint involvement often…
  • Abstract Number: 1505 • 2019 ACR/ARP Annual Meeting

    Persistence with Etanercept in Patients with Ankylosing Spondylitis or Psoriatic Arthritis in Germany: A Real-World Analysis

    Xenofon Baraliakos1, Denis Poddubnyy 2, Frank Behrens 3, Cinzia Curiale 4, Miriam Tarallo 4, Ana Cristina Hernandez Daly 5, Olaf Behmer 6, Joseph Cappelleri 7, Nicholas Hudson 8 and Christen Gray 8, 1Rheumatology Department, Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany, 2Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany, 3Rheumatology Goethe-University Frankfurt & Fraunhofer IME-TMP, Frankfurt, Germany, 4Pfizer Inc., Rome, Italy, 5Pfizer Inc., Athens, Greece, 6Pfizer Inc., Berlin, Germany, 7Pfizer Inc, Groton, CT, 8IQVIA, London, United Kingdom

    Background/Purpose: Ankylosing spondylitis (AS) and psoriatic arthritis (PsA) treatment includes biologics, prescribed on a long-term basis. As persistence data from real-world practice are limited, the…
  • Abstract Number: 2210 • 2019 ACR/ARP Annual Meeting

    Relationship Between Structural Spine Involvement and the Scanographic Bone Attenuation Coefficient of L1 in a Population of 73 Patients with Ankylosing Spondylitis

    Marine Fauny1, Frank VERHOEVEN 2, Edem Allado 1, Eliane Albuisson 3, Caroline Morizot 1, Astrid Pinzano-Watrin 4, Isabelle Chary-Valckenaere 3 and Damien Loeuille 5, 1CHRU Nancy, VANDOEUVRE, France, 2CHU Besancon, BESANCON, France, 3Centre Hospitalier Universitaire de Nancy, VANDOEUVRE, France, 4IMoPA. UMR 7365 CNRS, Vandoeuvre, France, 5Rheumatology, Nancy University Hospital and and UMR 7365 CNRS-UL IMoPA, Université de Lorraine, VANDOEUVRE, France

    Background/Purpose: Thoracic and/or thoraco-abdomino-pelvic (TAP) Computed Tomography (CT) may be performed during the follow up of patients with ankylosing spondylitis (AS) and are able to…
  • Abstract Number: L13 • 2018 ACR/ARHP Annual Meeting

    Long-Term Evaluation of Secukinumab in Ankylosing Spondylitis: 5 Year Efficacy and Safety Results from a Phase 3 Trial

    Xenofon Baraliakos1, Jürgen Braun2, Atul A. Deodhar3, Denis Poddubnyy4, Alan J. Kivitz5, Hasan Tahir6, Filip van Den Bosch7, Evie Maria Delicha8, Zsolt Talloczy9 and Anke Fierlinger9, 1Rheumazentrum Ruhrgebiet, Herne, and Ruhr University Bochum, Herne, Germany, Herne, Germany, 2Rheumazentrum Ruhrgebiet Herne, and Ruhr University Bochum, Herne, Germany, Herne, Germany, 3Oregon Health & Science University, Portland, Portland, OR, 4Rheumatology, Campus Benjamin Franklin Charité – Universitätsmedizin, Germany and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany, 5Altoona Arthritis & Osteoporosis Center, Duncansville, PA, 6Whipps Cross University Hospital, Barts Health NHS Trust, London, United Kingdom, 7Rheumatology, Universitair Ziekenhuis, Ghent, Belgium, Gent, Belgium, 8Novartis Pharma AG, Basel, Basel, Switzerland, 9Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, United States, East Hanover, NJ

    Background/Purpose: Clinical evaluation of efficacy and safety for long-term treatment for ankylosing spondylitis (AS) is important for treatment decision-making. Secukinumab (SEC), a fully human mAb…
  • Abstract Number: 285 • 2018 ACR/ARHP Annual Meeting

    Inflammatory Bowel Disease Is Associated with a Substantial Economic Burden in Patients with Psoriatic Arthritis and in Patients with Ankylosing Spondylitis

    Martin J. Bergman1, Patrick Zueger2, Jinlin Song3, Irina Pivneva4, Keith A. Betts3 and Avani D. Joshi5, 1Drexel University College of Medicine, Philadelphia, PA, 2AbbVie Inc., North Chicago, IL, 3Analysis Group, Inc., Los Angeles, CA, 4Analysis Group, Inc., Montreal, QC, Canada, 5AbbVie, Inc., North Chicago, IL

    Background/Purpose: Psoriatic arthritis (PsA) and ankylosing spondylitis (AS) belong to a group of inflammatory arthritides known to share similar extra-articular manifestations, such as inflammatory bowel…
  • Abstract Number: 691 • 2018 ACR/ARHP Annual Meeting

    A Service Evaluation of Reporting Standards of Computer Tomography Defined Sacroiliitis Suggestive of Axial Spondyloarthritis in Inflammatory Bowel Disease Patients Imaged for Non-Musculoskeletal Indications

    Chong Seng Edwin Lim1, Samantha Bee Lian Low2, Baljeet Dhillon2, Shin Azegami2, Andoni Paul Toms2 and Karl Gaffney1, 1Rheumatology, Norfolk and Norwich University Hospital, Norwich, United Kingdom, 2Radiology, Norfolk and Norwich University Hospital, Norwich, United Kingdom

    Background/Purpose: A combined service evaluation by the rheumatology and radiology department was undertaken to understand the frequency and reporting standards of Computer Tomography-defined Sacroiliitis (CTSI)…
  • Abstract Number: 1623 • 2018 ACR/ARHP Annual Meeting

    Insight into the Quality of Life of Patients with Ankylosing Spondylitis: Real-World Data from a US-Based Life Impact Survey

    James T. Rosenbaum1, Lisa Pisenti2, Yujin Park3 and Richard Howard4, 1Ophthalmology, Oregon Health & Science University and Legacy Devers Eye Institute, Portland, OR, 2UCB, Inc., Smyrna, GA, 3Novartis Pharmaceuticals Corporation, East Hanover, NJ, 4Spondylitis Association of America, Van Nuys, CA

    Background/Purpose: While severe pain and stiffness are common hallmarks of ankylosing spondylitis (AS), disease progression is slow and not always visible; however, the quality of…
  • Abstract Number: 2396 • 2018 ACR/ARHP Annual Meeting

    Reduction in the Utilization of Prednisone and/or Methotrexate Following the Initiation of Etanercept in Pediatric Patients

    Majed M M Khraishi1, Brad Millson2, John Woolcott3, Lisa Marshall4 and Heather Jones4, 1Memorial University of Newfoundland, St John's, NF, Canada, 2IQVIA, Kanata, ON, Canada, 3Global Outcomes & Evidence, Pfizer, Collegeville, PA, 4Pfizer, Collegeville, PA

     Background/Purpose: In Canada, the pediatric indications of etanercept (ETN) are active ankylosing spondylitis (AS), plaque psoriasis (PsO) and moderate to severely active juvenile idiopathic arthritis…
  • Abstract Number: 311 • 2018 ACR/ARHP Annual Meeting

    Magnetic Resonance Imaging of the Cervical Spine in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis Presenting with Chronic Neck Pain – a Systematic Comparison of Clinical Assessments

    Xenofon Baraliakos1, Mina Soltani2, Parham Damirchi2, Uta Kiltz3 and Jürgen Braun1, 1Ruhr-University Bochum, Herne, Germany, 2Rheumazentrum Ruhrgebiet, Herne, Germany, 3Rheumatology, Rheumazentrum Ruhrgebiet, Herne, and Ruhr University Bochum, Herne, Germany

    Background/Purpose: Despite the differences in pathogenesis, neck pain associated with functional limitation of the cervical spine is a frequent clinical symptom of patients with rheumatoid…
  • Abstract Number: 836 • 2018 ACR/ARHP Annual Meeting

    Genetic Risk Score Prediction in Ankylosing Spondylitis

    Zhixiu Li1, Erika De Guzman1, Jessica Harris1, Nurullah Akkoc2, Mahdi Mahmoudi3, Maxime Breban4, Chung-Tei Chou5, Michael Weisman6, Lianne S. Gensler7, Michael Ward8, Mohammad H. Rahbar9, Laura A. Diekman10, Tae-Hwan Kim11, Paul Leo1, John D. Reveille10, Paul Wordsworth12, Matthew Brown1 and Huji Xu13, 1Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Brisbane, Australia, Brisbane, Australia, 2Rheumatology, İzmir, Turkey, İzmir, Turkey, 3Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran, Tehran, Iran (Islamic Republic of), 4Hôpital Ambroise Paré, Assistance Publique-Hôpitaux de Paris, Boulogne, France, Boulogne, France, 5Division of Allergy-Immunology-Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Taipei, Taiwan, 6Cedars-Sinai Medical Center, Los Angeles, CA, USA, Los Angeles, CA, 7University of California San Francisco, San Francisco, CA, 8National Institutes of Health, Bethesda, MD, USA, Bethesda, MD, 9Biostatistics/Epidemiology/Research Design (BERD) Core | Center for Clinical and Translational Sciences, McGovern Medical School at the University of Texas Health Science Center at Houston, USA, Houston, TX, 10Rheumatology, McGovern Medical School at the University of Texas Health Science Center at Houston, USA, Houston, TX, 11Rheumatology, The Hospital for Rheumatic Diseases, Hanyang University, Seoul, Korea, Seoul, Korea, Republic of (South), 12Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK, Oxford, United Kingdom, 13School of Clinical Medicine, Tsinghua University, Beijing, China, Beijing, China

    Background/Purpose: The diagnosis of ankylosing spondylitis (AS) is delayed by on average 8–11 years after the onset of symptoms, and there is increasing evidence that…
  • Abstract Number: 1624 • 2018 ACR/ARHP Annual Meeting

    Real-World Insight into the Disease Burden and Treatment of Spondyloarthritis from a US-Based Life Impact Survey

    James T. Rosenbaum1, Lisa Pisenti2, Yujin Park3 and Richard Howard4, 1Ophthalmology, Oregon Health & Science University and Legacy Devers Eye Institute, Portland, OR, 2UCB, Inc., Smyrna, GA, 3Novartis Pharmaceuticals Corporation, East Hanover, NJ, 4Spondylitis Association of America, Van Nuys, CA

    Background/Purpose: Spondyloarthritis (SpA) is a group of chronic, inflammatory diseases associated with severe pain in the joints and entheses. There is limited evidence on real-world…
  • Abstract Number: 2430 • 2018 ACR/ARHP Annual Meeting

    Pregnancy in Women with Ankylosing Spondylitis Is Not Associated with Poor Obstetric Outcomes: Analysis of Nationwide Inpatient Sample Database 2003-2011

    Vikas Majithia and Shweta Kishore, Division of Rheumatology, University of Mississippi Medical Center, Jackson, MS

    Background/Purpose: Outcomes of pregnancy are well studied in a number of rheumatic diseases such as Rheumatoid Arthritis (RA) and systemic lupus erythematosus. When compared, there…
  • Abstract Number: 316 • 2018 ACR/ARHP Annual Meeting

    Eligibility Rates in Axial Spondyloarthritis Clinical Trials Based on Imaging Criteria

    Farhan A. Syed1, David Bennett1, Michael O'Connor1, Gabriele Pradella2 and Sarah Warner1, 1Scientific and Medical Services, PAREXEL International, Billerica, MA, 2Image Management, PAREXEL International, Billerica, MA

    Background/Purpose: Axial Spondyloarthritis (AxSpA) encompasses both non-radiographic (nr-AxSpA) as well as radiographic ankylosing spondylitis (AS) which displays structural changes at the sacro-iliac joint (SIJ).  Phase…
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