Abstracts tagged "ANCA associated vasculitis"

Abstract Number: 1590 • ACR Convergence 2020
Bone Health in ANCA – Associated Vasculitis Patients
Deepa Ragesh Panikkath¹, Sandy Lee² and Christina Downey², ¹Loma Linda University Health, Department of Rheumatology, Loma Linda, CA, ²Loma Linda University Medical Center, Redlands, CA
Background/Purpose: Glucocorticoids (GC) are an important mode of therapy in ANCA associated vasculitis (AAV), and osteoporosis (OP) and fractures are potential adverse effects seen. The…
Abstract Number: 1421 • ACR Convergence 2020
Clinical Features, Disease Activity and Prognosis of ANCA-Associated Vasculitis in US African Americans
Luis Palomino¹, Angelo Gaffo², Sebastian Sattui³ and Dongmei Sun², ¹University of Alabama at Birmingham Hospital, Birmingham, AL ²University of Alabama at Birmingham, Birmingham, AL, ³Hospital for Special Surgery, New York, NY
Background/Purpose: ANCA-associated vasculitis (AAV), including Granulomatosis with Polyangiitis (GPA), Eosinophilic Granulomatosis with Polyangiitis (EGPA) and Microscopic Polyangiitis (MPA), affect mostly Caucasians of European descent. Clinical…
Abstract Number: 2048 • ACR Convergence 2020
Comparison of Two Rituximab Regimens for Induction of Remission in Antineutrophil Cytoplasm Antibody-associated Vasculitis: Systematic Review and Meta-analysis
Valerie Benard¹, Cynthia Farhat², Melissa Zarandi-Nowroozi², Madeleine Durand³, Christian Pagnoux⁴, Pierre Charles⁵, Xavier Puechal⁶, Loïc Guillevin⁷ and Jean-Paul Makhzoum¹, ¹Vasculitis Clinic, Canadian Network for Research on Vasculitides (CanVasc), Department of Internal Medicine, Hopital du Sacre-Coeur de Montreal, University of Montreal, Montreal, QC, Canada, ²Department of Medecine, University of Montreal, Montreal, QC, Canada, ³Department of Internal Medicine, Centre Hospitalier de l’Universite de Montreal (CHUM) and Centre de Recherche du Centre Hospitalier de l’Universite de Montreal (CRCHUM), Montreal, QC, Canada, ⁴Vasculitis Clinic, Canadian Network for Research on Vasculitides (CanVasc), Department of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁵Department of Internal Medicine, Institut Mutualiste Montsouris, Paris, France, ⁶National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris-Descartes University, Paris, France, ⁷Department of Internal Medecine, National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris-Descartes University, Paris, France
Background/Purpose: Organ or life-threatening granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), two of the antineutrophil cytoplasm antibody-associated vasculitis (AAV), are treated with cyclophosphamide or…
Abstract Number: 1422 • ACR Convergence 2020
Healthcare Utilization Among Patients Diagnosed with ANCA-Associated Vasculitis Between 2007 and 2014 in a Multi-Center Cohort Linked to Medicare Claims Data
Zachary Wallace¹, Xiaoqing Fu², John Stone³, Hyon Choi⁴ and Rochelle Walensky², ¹Massachusetts General Hospital, Newton, MA, ²Massachusetts General Hospital, Boston, ³Massachusetts General Hospital, Concord, MA, ⁴Massachusetts General Hospital, Department of Medicine, Division of Rheumatology, Lexington, MA
Background/Purpose: ANCA-associated vasculitis (AAV) leads to complications that contribute to poor quality of life and survival. Systemic vasculitis is associated with high healthcare utilization but…
Abstract Number: 2050 • ACR Convergence 2020
Autoantibodies Targeting Complement Receptors C3aR and C5aR1 Are Decreased in ANCA-associated Vasculitis and Correlate with a Higher Relapse Rate
Sebastian Klapa¹, Antje Müller², Andreas Koch³, Anja Kerstein-Staehle⁴, Wataru Kaehler³, Harald Heidecke⁵, Susanne Schinke⁶, Markus Huber-Lang⁷, Martin Nitschke⁸, Silke Pitann⁹, Christian Karsten¹⁰, Gabriela Riemekasten¹¹ and Peter Lamprecht², ¹University of Lübeck and Institute of Experimental Medicine, Christian-Albrechts-University of Kiel c/o German Naval Medical Institute, Department of Rheumatology and Clinical Immunology, Luebeck, Germany, ²University of Lübeck, Department of Rheumatology and Clinical Immunology, Lübeck, Germany, ³Institute of Experimental Immunology, Christian-Albrechts-University Kiel, c/o German Naval Medical Institute, Kronshagen, Germany, ⁴University of Lübeck, Dept Rheumatology and Clinical Immunology, Luebeck, Germany, ⁵CellTrend GmbH, Luckenwalde, Germany, ⁶University of Lübeck, Department of Rheumatology and Clinical Immunology, Luebeck, Germany, ⁷Institute of Clinical and Experimental Trauma Immunology, University Hospital Ulm, Ulm, Germany, ⁸Department of Internal Medicine I, Transplant Center, University of Lübeck, Luebeck, Germany, ⁹University of Lübeck, Department of Rheumatology and Clinical Immunology,, Luebeck, Germany, ¹⁰Institute of Systemic Inflammation Research, University of Lübeck, Luebeck, Germany, ¹¹University of Lübeck, Department of Rheumatology and Clinical Immunology,, Lübeck, Germany
Background/Purpose: Activation of the alternative and common terminal complement pathways has been shown in ANCA-associated vasculitis (AAV). Circulating titers of the anaphylatoxin C5a are increased…
Abstract Number: 1424 • ACR Convergence 2020
Outcomes of Hospitalizations for Acute Myocardial Infarction in Patients with ANCA Associated Vasculitis from the National Inpatient Sample
Atefeh Vafa¹, Marielys Figueroa Sierra¹, Omid Behnamfar², Hamayon Babary¹, Suraiya Afroz¹ and Yih Chang Lin³, ¹University of South Florida, Tampa, FL, ²University of California San Diego, La Jolla, CA, ³University of South Florida, Morsani College of Medicine, Tampa, FL
Background/Purpose: Several studies in the past have shown significantly increased risks of cardiovascular disease in patients with ANCA associated vasculitis (AAV). This association is thought…
Abstract Number: 2051 • ACR Convergence 2020
Localized versus Systemic Granulomatosis with Polyangiitis: Data from the French Vasculitis Study Group Database
Michele Iudici¹, Christian Pagnoux², Delphine Courvoisier³, Pascal Cohen⁴, Mohamed Hamidou⁵, Achille Aouba⁶, François Lifermann⁷, Marc Ruivard⁸, Olivier Aumaitre⁹, Bernard Bonnotte¹⁰, Julien Campagne¹¹, Olivier Decaux¹², Eric Hachulla¹³, Alexandre Karras¹⁴, Chahéra Khouatra¹⁵, Noémie Jourde-Chiche¹⁶, Jean-François Viallard¹⁷, Pascal Godmer¹⁸, Claire Blanchard-Delaunay¹⁹, Alain Le Quellec²⁰, Thomas Quéméneur²¹, Claire de Moreuil²², Alexis Regent⁴, Benjamin Terrier⁴, Luc Mouthon⁴, Loïc Guillevin⁴ and Xavier Puechal⁴, ¹National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris-Descartes University and Geneva University Hospitals, Geneva, Switzerland, ²Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ³Division of rheumatology, Geneva University Hospitals, Geneva, Switzerland, ⁴National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris-Descartes University, Paris, France, ⁵Department of Internal Medicine, Hôtel-Dieu, CHU Nantes, Nantes, France, ⁶Department of Internal Medicine, CHU Côte de Nacre, Caen, France, ⁷Department of Internal Medicine, CH Côte d’Argent, Dax, France, ⁸Department of Internal Medicine, CHU Estaing, Clermont Ferrand, France, ⁹Department of Internal Medicine, CHU Gabriel Montpied, Clermont Ferrand, France, ¹⁰CHU Dijon, Dijon, France, ¹¹Department of Internal Medicine, Hôpitaux Privés de Metz, Metz, France, ¹²CHU Rennes, Rennes, France, ¹³Department of Internal Medicine, CHRU, Lille Cedex, France, ¹⁴Department of Nephrology, Hôpital Européen Georges Pompidou, Paris, France, ¹⁵Department of Respiratory Medicine, CHU Louis Pradel, Lyon, France, ¹⁶Department of Nephrology, CHU de la Conception, Marseille, France, ¹⁷Department of Internal Medicine, CHU Haut-Lévêque, Bordeaux, France, ¹⁸Department of Internal Medicine, CH Bretagne Atlantique, Vannes, France, ¹⁹Department of Internal Medicine, CH, Niort, France, ²⁰Department of Internal Medicine, CHU Saint Eloi, Montpellier, France, ²¹Department of Internal Medicine, CH, Valenciennes, France, ²²Department of Internal Medicine, CHU Cavale Blanche, Brest, France
Background/Purpose: The clinical picture at onset and evolution of localized forms of granulomatosis with polyangiitis (L-GPA) have already been investigated but, to our knowledge, have…
Abstract Number: 1426 • ACR Convergence 2020
Prevalence of ANCA-associated Vasculitis and Spatial Association with Quarries in a French Northeast Region: A Capture-recapture and Geospatial Analysis
Stéphane Giorgiutti¹, Yannick Dieudonné¹, Olivier Hinschberger², Benoit Nespola³, Julien Campagne⁴, Hanta Nirina Rakotoarivelo⁵, Thierry Hannedouche⁶, Bruno Moulin⁶, Gilles Blaison⁵, Jean-Christophe Weber⁷, Marie-Caroline Dalmas⁸, Frederic De Blay⁹, Dan Lipsker¹⁰, Francois Chantrel¹¹, Jacques-Eric Gottenberg¹², Yves Dimitrov¹³, Olivier Imhoff¹⁴, Pierre-Edouard Gavand¹⁵, Emmanuel Andres¹⁶, Christian Debry¹⁷, Yves Hansmann¹⁸, Alexandre Klein¹⁹, Caroline Lohmann²⁰, François Mathiaux²¹, Aurélien Guffroy¹, Vincent Poindron¹, Thierry Martin¹, Anne-Sophie Korganow¹ and Laurent Arnaud²², ¹Department of Clinical Immunology and Internal Medicine, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, ²Department of Internal Medicine, Hôpital Emile Muller, Mulhouse, Mulhouse, France, ³Department of Immunobiology, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, ⁴Department of Internal Medicine, Hôpitaux Privés de Metz, Metz, France, ⁵Department of Internal Medicine, Hôpitaux Civils de Colmar, Colmar, France, ⁶Department of Nephrology, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, ⁷Department of Internal Medicine, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, ⁸Department of Internal Medicine Endocrinology and Nutrition, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, ⁹Pneumology, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, ¹⁰Department of Dermatology, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, ¹¹Department of Nephrology, Hôpital Emile Muller, Mulhouse, Strasbourg, France, ¹²Strasbourg University Hospital, Strasbourg, France, ¹³Department of Nephrology, Centre hospitalier de Haguenau, Haguenau, France, ¹⁴Department of Nephrology, Clinique Saint-Anne, Strasbourg, Strasbourg, France, ¹⁵Department of Internal Medicine, Clinique Rhena, Strasbourg, Strasbourg, France, ¹⁶Department of Internal Medicine, Diabete and Metabolic Diseases, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, ¹⁷Department of Otorhinolaryngology, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, ¹⁸Department of Infectious Diseases, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, ¹⁹Department of Nephrology, Hôpitaux Civils de Colmar, Colmar, France, ²⁰Department of Microbiology, Hôpital Emile Muller, Mulhouse, Mulhouse, France, ²¹Department of Biology, Hôpitaux Civils de Colmar, Strasbourg, France, ²²Department of Rheumatology, Hôpitaux Universitaires de Strasbourg, Strasbourg, France
Background/Purpose: Studies addressing the epidemiology of ANCA-associated vasculitides (AAV) in different countries reported various prevalence rates and suggested that incidence may have increased over the…
Abstract Number: 2052 • ACR Convergence 2020
Extended Follow-Up of Patients Recruited to a Randomized, Controlled Trial of Rituximab versus Azathioprine After Induction of Remission with Rituximab for Patients with ANCA-Associated Vasculitis and Relapsing Disease
Rona Smith¹, David Jayne² and Peter A. Merkel³, ¹University of Cambridge, Cambridge, United Kingdom, ²Department of Medicine, Vasculitis and Lupus Research Group, University of Cambridge, Cambridge, UK, Cambridge, United Kingdom, ³Division of Rheumatology University of Pennsylvania, Philadelphia, PA
Background/Purpose: Rituximab is an effective therapy for induction of remission in ANCA-associated vasculitis (AAV). However, the effect of rituximab is not sustained, and subsequent relapse…
Abstract Number: 1430 • ACR Convergence 2020
The Role of Lung Biopsy in Pediatric ANCA-associated Vasculitis
Edouard Sayad¹, Tiphanie Vogel¹, David Moreno McNeill¹, Nahir Cortes-Santiago¹, David Spielberg¹, Kalyani Patel¹ and Manuel Silva Carmona¹, ¹Baylor College of Medicine/Texas Children's Hospital, Houston, TX
Background/Purpose: Anca-associated vasculitis (AAV) is characterized by vascular inflammation in multiple organs. The diagnosis can be made clinically using a number of different criteria. The…
Abstract Number: PP02 • ACR Convergence 2020
Low- and Hi-Tech Tools for Enhancing Patient-Hospital Care Team Communication in the Context of Rare Disease
Ida Hakkarinen¹, ¹Vasculitis Patient-Powered Research Network (VPPRN) / Member, Vasculitis Foundation, Greenbelt, MD
Background/Purpose: For over two years, I experienced a variety of disparate symptoms including: joint aches, sinus congestion, shortness of breath and chronic cough. An episode…
Abstract Number: 1431 • ACR Convergence 2020
Interstitial Lung Disease in Patients with ANCA Associated Vasculitis – a Prospective Single Centre Study
Alojzija Hocevar¹, Katja Perdan Pirkmajer¹, Matija Tomsic¹ and Ziga Rotar¹, ¹University Medical Center Ljubljana, LJUBLJANA, Slovenia
Background/Purpose: Recently, an association between anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and interstitial lung disease (ILD) has been uncovered. We aimed to determine the rate…
Abstract Number: 0060 • ACR Convergence 2020
ANCA-associated Vasculitis in Caucasian and Hispanics of the Inland Empire of Southern California
Sandy Lee¹, Patil Injean¹, Paulina Tran², Deepa Panikkath¹ and Christina Downey¹, ¹Loma Linda University Medical Center, Redlands, CA, ²UC Riverside School of Medicine, Riverside, CA
Background/Purpose: ANCA-associated vasculitis (AAV) is often studied in the Caucasian population with few studies looking at the disease in other races. Disease presentation and treatment…
Abstract Number: 1432 • ACR Convergence 2020
Thyroid Disease in Patients with ANCA-Associated Vasculitis
Tanaz Kermani¹, David Cuthbertson², Simon Carette³, Nader Khalidi⁴, Curry L. Koening⁵, Carol Langford⁶, Carol McAlear⁷, Paul Monach⁸, Larry Moreland⁹, Christian Pagnoux¹⁰, Philip Seo¹¹, Ulrich Specks¹², Antoine Sreih¹³, Kenneth Warrington¹² and Peter Merkel¹³, ¹University of California Los Angeles, West Hills, CA, ²University of South Florida, Tampa, ³Division of Rheumatology, Mount Sinai Hospital and University Health Network, University of Toronto, Toronto, ON, Canada, ⁴McMaster University, Hamilton, ON, Canada, ⁵University of Utah, Salt Lake City, ⁶Cleveland Clinic, Moreland Hills, OH, ⁷University of Pennsylvania, Philadelphia, ⁸Brigham and Women's, Boston, ⁹University of Pittsburgh, Denver, CO, ¹⁰Vasculitis Clinic, Canadian Network for Research on Vasculitides (CanVasc), Department of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ¹¹Johns Hopkins University, Baltimore, MD, ¹²Mayo Clinic, Rochester, MN, ¹³University of Pennsylvania, Philadelphia, PA
Background/Purpose: Prior studies have found increased prevalence of thyroid disease in patients with ANCA-associated vasculitis (AAV), especially positive myeloperoxidase (MPO)-ANCA, but a majority of the…
Abstract Number: 0418 • ACR Convergence 2020
Prevalence of Thyroid Disease Among Patients with Vasculitis
Tanaz Kermani¹, David Cuthbertson², Simon Carette³, Nader Khalidi⁴, Curry L. Koening⁵, Carol Langford⁶, Carol McAlear⁷, Paul Monach⁸, Larry Moreland⁹, Christian Pagnoux¹⁰, Philip Seo¹¹, Ulrich Specks¹², Antoine Sreih¹³, Kenneth Warrington¹² and Peter Merkel¹³, ¹David Geffen School of Medicine / University of California, Los Angeles, CA, ²University of South Florida, Tampa, ³Division of Rheumatology, Mount Sinai Hospital and University Health Network, University of Toronto, Toronto, ON, Canada, ⁴McMaster University, Hamilton, ON, Canada, ⁵University of Utah, Salt Lake City, ⁶Cleveland Clinic, Moreland Hills, OH, ⁷University of Pennsylvania, Philadelphia, ⁸Brigham and Women's, Boston, ⁹University of Pittsburgh, Denver, CO, ¹⁰Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ¹¹Johns Hopkins University, Baltimore, MD, ¹²Mayo Clinic, Rochester, MN, ¹³University of Pennsylvania, Philadelphia, PA
Background/Purpose: Previous studies have reported higher risk of thyroid disease in patients with giant cell arteritis (GCA) and ANCA-associated vasculitis (AAV) compared to age- and…

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