Abstract Number: 2450 • 2017 ACR/ARHP Annual Meeting
Comparative Effectiveness of Abatacept Versus TNFi in Patients with RA Who Are CCP+ in the United States Corrona Registry
Background/Purpose: Anti-cyclic citrullinated peptide positivity (CCP+) is associated with a better response to abatacept than anti-CCP negativity in patients with RA1,2; however, there are no…Abstract Number: 487 • 2017 ACR/ARHP Annual Meeting
ARE ANTI-Citrullinated Protein Antibody Levels Associated with Periodontal Disease in Rheumatoid Arthritis?
Background/Purpose: Positivity of anti-citrullinated peptides antibodies (ACPA) indicates severity in Rheumatoid Arthritis (RA). There is evidence for chronic periodontitis (PD) in RA autoimmune response by…Abstract Number: 2791 • 2017 ACR/ARHP Annual Meeting
Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL) and Marginal Jawbone Loss Predates the Onset of Rheumatoid Arthritis
Background/Purpose: Previous studies have shown a higher incidence of alveolar bone loss in patients with rheumatoid arthritis (RA) and that patients with periodontitis are at…Abstract Number: 55 • 2016 ACR/ARHP Annual Meeting
Identification of Endogenous Autoantigens Bound to Anti-Citrullinated Peptide Antibodies in Rheumatoid Arthritis: A Key Role for Citrulline Residues in Histone 4
Background/Purpose: Anti-Citrullinated Peptides Antibodies (ACPA) aid in rheumatoid arthritis (RA) diagnosis. The nature of autoantigens specifically bound to ACPA immune complex in vivoremains unclear. We…Abstract Number: 571 • 2016 ACR/ARHP Annual Meeting
High Titer Rheumatoid Arthritis Antibodies Distinguish Between PAD2 and PAD4 Citrullinated Fibrinogen
Background/Purpose: Most patients with rheumatoid arthritis (RA) harbor antibodies to citrullinated autoantigens, such as citrullinated fibrinogen. Two isoforms of peptidylarginine deiminase (PAD), PAD2 and PAD4,…Abstract Number: 2035 • 2016 ACR/ARHP Annual Meeting
Dosage Contribution of a Non-Classical HLA Gene, HLA-Doa, to the Risk of Rheumatoid Arthritis
Background/Purpose: Despite the progress in human leukocyte antigen (HLA) causal variant mapping, independent localization of major histocompatibility complex (MHC) risk from classical HLA genes is…Abstract Number: 572 • 2016 ACR/ARHP Annual Meeting
Anti-Periodontal Bacteria Antibody Titers Are Inversely Correlated with ACPA in RA-Free Individuals with Periodontal Disease Compared to Community Controls
Background/Purpose: Rheumatoid arthritis (RA) and periodontal disease (PD) are comorbid conditions that share multiple underlying risk factors and pathophysiological features. A dysbiotic periodontal microbiome might…Abstract Number: 2107 • 2016 ACR/ARHP Annual Meeting
Targeting Mir-155 in Rheumatoid Arthritis B Cells Reduces Antibody Production
Background/Purpose: Better understanding of epigenetic regulatory mechanisms in RA pathogenesis will facilitate the development of new biomarkers or therapeutic strategies. MicroRNAs are post-transcriptional regulators that…Abstract Number: 575 • 2016 ACR/ARHP Annual Meeting
Differences in Histological Scores and Histoclinical Correlations in ACPA- Versus ACPA+ Rheumatoid Arthritis Patients
Background/Purpose: Differences in the pathogenesis of ACPA- versus ACPA+ rheumatoid arthritis are still poorly understood. In this study, we compared patterns of synovial changes in…Abstract Number: 2111 • 2016 ACR/ARHP Annual Meeting
Generation and Characterization of Anti-Citrullinated Protein Antibody-Producing B-Cell Clones
Background/Purpose: Rheumatoid arthritis (RA) is the most frequent form of autoimmune arthritis with a prevalence of almost 1% worldwide. Anti-citrullinated protein antibodies (ACPA) are the…Abstract Number: 582 • 2016 ACR/ARHP Annual Meeting
ACPA Induce Pathogenic Cytokines Expression in PBMC of ACPA+-RA Patients and Inhibition of Its Effect By Cit-ME a Synthetic Citrullinated Peptide
ACPA induce pathogenic cytokines expression in PBMC of ACPA+-RA patients and inhibition of its effect by Cit-ME a synthetic citrullinated peptide.Smadar Gertel1, Gidi Karmon1, Eszter…Abstract Number: 2496 • 2016 ACR/ARHP Annual Meeting
DMARD, Biologic and Small Molecule Drug Use Among ACPA Positive and ACPA Negative RA Patients in a Tertiary Referral Center
Background/Purpose: Rheumatoid arthritis (RA) can be divided into two major subsets based on the presence or absence of antibodies to citrullinated peptide antigens (ACPA). Some…Abstract Number: 583 • 2016 ACR/ARHP Annual Meeting
Associations of Serum Anti-Citrullinated Proteins and Cytokines with Radiographic Scores in African-American Rheumatoid Arthritis Patients
Background/Purpose: Serum anti-citrullinated proteins (ACPA, including anti-CCP antibodies) and rheumatoid factor (RF) are critical diagnostic markers for RA, and are associated with more severe radiographic…Abstract Number: 2612 • 2016 ACR/ARHP Annual Meeting
Sero-Positivity for Rheumatoid Factor Is an Independent Predictor for Achievement of Good EULAR Response at 24 Weeks in ACPA Positive Rheumatoid Arthritis Patients Treated with Abatacept: Results from Japanese Multicenter Registry
Background/Purpose: Abatacept is a new class of biologic agent for the treatment of rheumatoid arthritis (RA) that inhibits T cell activation by binding to CD80/86.…Abstract Number: 584 • 2016 ACR/ARHP Annual Meeting
Glycoprotein VI: A Potential Target for ACPA-Mediated Platelet Activation?
Background/Purpose: Arterial thrombosis is a major cause of mortality in rheumatoid arthritis (RA),especially in anti-citrullinated protein antibody (ACPA)-positive patients Recent studies suggest that platelet activation…
- « Previous Page
- 1
- …
- 3
- 4
- 5
- 6
- 7
- …
- 13
- Next Page »