ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstracts tagged "ACPA"

  • Abstract Number: 54 • 2018 ACR/ARHP Annual Meeting

    In a Macaque Model of RA By Immunization with Citrullinated Peptides, the Valine in the 11 Position of the DRB1 Molecule Has Greater Impacts on T-Cell Response to Citrullinated Peptides Than the 70-74 Position in the Shared Epitope

    Samuel Bitoun1, Pierre Roques2, Roger Le Grand3 and Xavier Mariette4, 1INSERM U1184, IMVA, Paris Sud University,LabEx LERMIT, Le Kremlin Bicêtre, France, 2Immunology of viral infections and autoimmune diseases, IDMIT Infrastructure CEA - Université Paris Sud - INSERM U1184, Fontenay-Aux-Roses,, France, 3Immunology of viral infections and autoimmune diseases, IDMIT Infrastructure CEA - Université Paris Sud - INSERM U1184, Fontenay-Aux-Roses, France, 4Rheumatology, Université Paris Sud, Le Kremlin Bicêtre, France

    Background/Purpose: Among genetic risk factors of RA, HLA class II molecules confers the highest risk of ACPA positive RA. The shared epitope (SE) hypothesis that…
  • Abstract Number: 1826 • 2018 ACR/ARHP Annual Meeting

    From Cancer to Autoimmunity : A New Model of Rheumatoid Arthritis Emerging from a Constitutional Genetic Approach Used in Low Penetrance Cancers

    Geraldine Falgarone1,2, Morad El Bouchtaoui3, Marcio Do Cruzeiro4, Christophe Leboeuf5,6,7, Irmine Loisel-Ferreira5,6, Carèle Frédonie7, Chrystophe Ferreira8, Rachida Ait El Far5, Marc Espié9, Bruno Cassinat10, Jean-Jacques Kiladjian11, Jean-Paul Feugeas12,13, Anne Janin5,6,14 and Guilhem Bousquet2,5,15, 1HUPSSD, Avicenne Hospital, Rheumatology, APHP, Bobigny, France, 2Paris 13 University, SMBH, Bobigny, France, 3INSERM UMR-S 1165, PARIS, France, 4Plateforme de Recombinaison Homologue, Institut Cochin, INSERM U1016, Paris, France, 5INSERM UMR-S 1165, Paris, France, 6Université Paris Diderot, Paris, France, 7INSERM U944, Paris, France, 8Plateforme ANIMA5, Université Paris Descartes, Paris, France, 9Centre des Maladies du Sein, APHP, Hôpital Saint-Louis, Paris, France, 10Laboratoire de BIologie Cellulaire, APHP, Hôpital Saint-Louis, Paris, France, 11Centre d'Inverstigation Clinique, APHP, Hôpital Saint-Louis, Paris, France, 12INSERM U1137, Paris, France, 13Département de Biologie, Université Franche-Comté, Besançon, France, 14Service de Pathologie, APHP, Hôpital Saint-Louis, Paris, France, 15Service d'Oncologie médicale, APHP, Hôpital Avicenne, Bobigny, France

    Background/Purpose: High-speed technologies for genome sequencing have completely changed the study of disease genetics, but with limited knowledge of the functional value of most genetic…
  • Abstract Number: 67 • 2018 ACR/ARHP Annual Meeting

    Intestinal Inflammation and Netosis Associate with the Presence of Stool IgA ACPA in Subjects at-Risk for RA

    Widian Jubair1, Elizabeth A. Bemis2, Yuko Okamoto3, Marie L. Feser3, Jennifer Seifert3, M. Kristen Demoruelle3, Jill M. Norris4, Kevin D. Deane3, V. Michael Holers5 and Kristine A Kuhn1,6, 1Rheumatology, University of Colorado Denver, Aurora, CO, 2Epidemiology, Colorado School of Public Health, Aurora, CO, 3Division of Rheumatology, University of Colorado Denver, Aurora, CO, 4Department of Epidemiology, Colorado School of Public Health, Aurora, CO, 5Rheumatology Division, University of Colorado Denver, Aurora, CO, 6Mucosal Inflammation Program, University of Colorado Denver, Aurora, CO

    Background/Purpose: Anti-citrullinated protein antibodies (ACPA) and inflammation characterized by neutrophil extracellular trap (NET)osis have been detected at mucosal sites such as the lung and periodontium…
  • Abstract Number: 1976 • 2018 ACR/ARHP Annual Meeting

    Sequencing of the MHC Region Defines HLA-DQA1 As Driven Risk for Anti-Citrullinated Protein Antibodies (ACPA)-Positive Rheumatoid Arthritis in Han Population

    Jianping Guo1, Tao Zhang2, Hongzhi Cao2, Xiaowei Li2, Mengru Liu1, Yundong Zou1 and Zhan-Guo Li1, 1Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, China, 2Beijing Genomics Institute (BGI)-Shenzhen, Shenzhen, China

    Background/Purpose: The strong genetic contribution of the major histocompatibility complex (MHC) to rheumatoid arthritis (RA) susceptibility has been generally attributed to HLA-DRB1. However, due to…
  • Abstract Number: 72 • 2018 ACR/ARHP Annual Meeting

    Altered Serologic Responses to Epstein Barr Virus Precede Clinical Disease Development in Rheumatoid Arthritis

    Heather M. Berens1, Elizabeth A. Bemis2, M. Kristen Demoruelle1, John B. Harley3, Judith A. James4, Jess Edison5, Kevin D. Deane1, Jill M. Norris6 and V. Michael Holers1, 1Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 2Epidemiology, Colorado School of Public Health, Aurora, CO, 3Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4University of Oklahoma Health Sciences Center, Oklahoma City, OK, 5Division of Rheumatology, Walter Reed National Military Medical Center, Bethesda, MD, 6Department of Epidemiology, Colorado School of Public Health, Aurora, CO

    Background/Purpose:    EBV infects B cells and is associated with several autoimmune diseases, including RA.  Prior studies have shown that patients with active classified RA…
  • Abstract Number: 2045 • 2018 ACR/ARHP Annual Meeting

    Specific Anti-Citrullinated Protein Antibodies Profiles Are Associated with Rheumatoid Arthritis Related Interstitial Lung Disease

    Pierre-Antoine Juge1, Leonor Nogueira2, Guy Serre2, René-Marc Flipo3, Lidwine Wemeau-Stervinou4, Thierry Schaeverbeke5, Claire Dromer6, Sylvain Adam-Marchand7, Marie-Christophe Boissier8, Hilario Nunes9, Raphaël Borie10, Bruno Crestani10 and Philippe Dieude10, 1Rhumatologie, Hôpital Bichat - Claude Bernard, Paris, France, 2Unité Différenciation Épidermique et Autoimmunité Rhumatoïde, Unité Mixte de Recherche, INSERM, Toulouse, France, 3Hôpital Roger Salengro, Lille, France, 4Pneumologie, CHRU de Lille, Lille, France, 5Department of Rheumatology, Bordeaux University Hospital, BORDEAUX, France, 6Imagerie Thoracique et Cardiovasculaire, CHU Bordeaux, Bordeaux, France, 7Pneumology, Centre Hospitalier Universitaire de Tours, Tours, France, 874 rue Marcel Cachin, INSERM, Bobigny, France, 9Pulmonary diseases department, Avicenne Hospital (AP-HP), Bobigny, France, 10Université Paris-Diderot, Paris, France

    Background/Purpose: The identification of peripheral blood markers of rheumatoid arthritis-associated interstitial lung disease (RA-ILD) may facilitate an earlier diagnosis and provide insight regarding the pathogenesis…
  • Abstract Number: 410 • 2017 ACR/ARHP Annual Meeting

    Association between Anti-Citrullinated Protein Antibody Status and the Incidence of Erosive Disease in Patients with RA

    Leslie R Harrold1, Heather J. Litman2, SE Connolly3, E Alemao3, Sabrina Rebello4, W Hua2 and Joel Kremer5, 1University of Massachusetts Medical School, Worcester, MA, 2Corrona, Southborough, MA, 3Bristol-Myers Squibb, Princeton, NJ, 4Corrona, LLC, Southborough, MA, 5Albany Medical College and The Center for Rheumatology, Albany, NY

    Background/Purpose: RA is characterized by the production of autoantibodies including anti-citrullinated protein antibodies (ACPAs).1 ACPAs are considered a prognostic indicator for more severe RA and…
  • Abstract Number: 1432 • 2017 ACR/ARHP Annual Meeting

    The Prognostic Value of IgA Subtypes of Rheumatoid Factor and Anti-Citrullinated Protein Antibodies (ACPA)  for Prediction of Therapeutic Responses to TNF Inhibitory Therapy in Patients with Rheumatoid Arthritis

    Daniela Sieghart1, Farideh Alasti2, Paul Studenic1 and Günter Steiner2, 1Medical University Vienna, Division of Rheumatology, Department of Internal Medicine III, Vienna, Austria, 2Rheumatology, Medical University of Vienna, Vienna, Austria

    Background/Purpose: Rheumatoid factor (RF) and Anti-Citrullinated Protein antibodies (ACPA) are the most specific diagnostic markers of rheumatoid arthritis (RA). These antibodies are predominantly of the…
  • Abstract Number: 413 • 2017 ACR/ARHP Annual Meeting

    Economic Burden Associated with Anti-Cyclic Citrullinated Peptide Antibody Positivity in Patients Newly Diagnosed with RA

    J An1, Z Bider2, J Kang1, E Alemao3, SE Connolly3 and TC Cheetham1, 1Western University of Health Sciences, Pomona, CA, 2Southern California Permanente Medical Group, Pasadena, CA, 3Bristol-Myers Squibb, Princeton, NJ

    Background/Purpose: Anti-cyclic citrullinated peptide (anti-CCP) antibody positivity has been suggested as a strong predictor of joint erosion as well as a potential biomarker for guiding…
  • Abstract Number: 1454 • 2017 ACR/ARHP Annual Meeting

    Association of Poor Prognostic Factors with Medication Persistence Among Adult RA Patients within a Community of Rheumatology Clinics

    Damemarie Paul1, Laura McDonald2, Aarti Rao3, Ruthwik Anupindi4 and Keith Knapp5,6, 1HEOR, Bristol Myers Squibb, Lawrence Township, NJ, 2CORDS, Bristol Myers Squibb, Uxbridge, United Kingdom, 3Analytics, Mu-Sigma, Bengaluru, India, 4Analytics, Mu-Sigma, Lawrence Township, NJ, 5Arthritis Northwest PLLC., Spokane, WA, 6Discus Analytics LLC., Spokane, WA

    Background/Purpose: A fixed treatment paradigm often exists for Rheumatoid Arthritis(RA) patient(pts)1. However, RA is a heterogeneous disease and differences in pts’ serostatus affect disease progression.…
  • Abstract Number: 432 • 2017 ACR/ARHP Annual Meeting

    ACPA and RF As Predictors of Sustained Clinical Remission in Rheumatoid Arthritis Patients: Data from a Rheumatoid Arthritis Cohort

    Janet E. Pope1, Emmanouil Rampakakis2, Mohammad Movahedi3, Angela Cesta3, John S. Sampalis4 and Claire Bombardier3, 1Department of Medicine, Division of Rheumatology, University of Western Ontario, St Joseph's Health Care, London, ON, Canada, 2JSS Medical Research, Montreal, QC, Canada, 3Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, 4McGill University, Montreal, QC, Canada

    ACPA and RF as Predictors of Sustained Clinical Remission in Rheumatoid Arthritis Patients: Data From a Rheumatoid Arthritis CohortBackground/Purpose: Positive serology for anti-citrullinated protein antibody…
  • Abstract Number: 2012 • 2017 ACR/ARHP Annual Meeting

    First Description of Tenosynovitis Prevalence in a Large Cohort of ACPA-Positive Patients

    Gisela Eugénio1,2,3, Kulveer Mankia3,4, Peta Pentony2,3, Jackie L. Nam2,3, Laura Hunt2,3, Hanna Gul2,3, Richard J. Wakefield2,3 and Paul Emery3,5, 1Rheumatology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, 2Leeds Teaching Hospitals NHS Trust, NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 3University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom, 4Rheumatology, Leeds Teaching Hospitals NHS Trust, NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 5NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose: Tenosynovitis has been regarded as a feature of RA, although its true prevalence in early stages has not been firmly established. The aim of…
  • Abstract Number: 459 • 2017 ACR/ARHP Annual Meeting

    Disease Course in Seronegative RA Patients Classified According to the 2010 ACR/EULAR Criteria

    Lena Bugge Nordberg1, Siri Lillegraven2, Anna-Birgitte Aga2, Inge C Olsen3, Elisabeth Lie4, Hilde B Hammer2, Till Uhlig2, Désirée van der Heijde5, Tore Kvien6 and Espen A. Haavardsholm2, 1Departement of Rheumatology, Diakonhjemmet hospital, oslo, Norway, 2Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 5Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 6Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose: The development of the 2010 classification criteria for rheumatoid arthritis (RA) has led to a redefinition of the patient population, including classification of seropositive…
  • Abstract Number: 2016 • 2017 ACR/ARHP Annual Meeting

    Favourable Changes in Power Doppler Scores in the Feet over 1-Year in an Early Rheumatoid Arthritis Cohort: The Role of Rheumatoid Factor and Anti–Citrullinated Protein Antibody

    Karen A. Beattie1, Hanyan Zou2, George Ioannidis3 and Maggie Larche1, 1Medicine, McMaster University, Hamilton, ON, Canada, 2McMaster University, Hamilton, ON, Canada, 3St Joseph's Healthcare Hamilton, Hamilton, ON, Canada

    Background/Purpose : MTP joints are seldom examined in routine clinical visits. As such, it is important to understand how the standard treatment of patients with…
  • Abstract Number: 478 • 2017 ACR/ARHP Annual Meeting

    Ectopic Lymphoid Tissue in the Lung Is Uniquely Associated with the ACPA IgA Isotype Even in Absence of Classifiable RA

    Lindsay B. Kelmenson1, M. Kristen Demoruelle1, Carlyne D. Cool2 and Kevin D. Deane1, 1Rheumatology Division, University of Colorado Denver, Aurora, CO, 2Pathology, University of Colorado Denver, Aurora, CO

    Background/Purpose: Antibodies to citrullinated protein antigens (ACPA) precede the development of rheumatoid arthritis (RA) and may be generated in the lung of established and preclinical…
  • « Previous Page
  • 1
  • 2
  • 3
  • 4
  • 5
  • …
  • 13
  • Next Page »
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology