2015 ACR/ARHP Annual Meeting Archives

Abstract Number: 2548

M-CSF-R Is a Critical Determinant for the Differentiation of Classical to Non-Classical Monocytes
Abstract Number: 1908

Macitentan Responsiveness Supports the Validity of a Murine Model of Pulmonary Hypertension in Scleroderma Associated with Altered Tgfbeta/BMPR2 Signalling
Abstract Number: 1456

Macrophage Activation Syndrome and Familial Hemophagocytic Lymphohistiocytosis: Is Their Clinical Phenotype Really Similar?
Abstract Number: 2424

Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis Patients Treated with Canakinumab: Results from Phase 3 Trial Program
Abstract Number: 3217

Macrophage Depletion Using a Specific CSF-1R Kinase Inhibitor Ameliorates Kidney and Skin Disease in a Mouse Model of Systemic Lupus Erythematosus
Abstract Number: 2208

Macrophage Migration Inhibitory Factor: A Novel Biomarker in Ankylosing Spondylitis That Can Drive Spinal Fusion
Abstract Number: 424

Magnetic Resonance and Echocardiographic Strain Rate Imaging for the Early Detection of Cardiac Involvement in Juvenile Systemic Sclerosis
Abstract Number: 313

Magnetic Resonance Imaging Outcomes Using an Intra-Articular Injection (SM04690) in the Treatment of Osteoarthritis of the Knee: Interim, Exploratory Analysis of Results from a Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study
Abstract Number: 2356

Major Cardiovascular Events in Gout Patients with Cardiovascular Disease or Heart Failure and Chronic Kidney Disease Initiating on Allopurinol or Febuxostat (Uloric)
Abstract Number: 2671

Male Gender and Higher Hemoglobin Predict Response to Methotrexate in Rheumatoid Arthritis
Abstract Number: 1684

Malignancies in Patients with Incident Psoriatic Arthritis 1970-2008 in Relation to a Comparator Cohort: A Population-Based Case-Control Study
Abstract Number: 571

Malignancy Data in Tofacitinib-Treated Japanese Patients with Rheumatoid Arthritis
Abstract Number: 1386

Malignancy Prevalence Is Increased Among Patients before the Onset of IgG4-Related Disease
Abstract Number: 399

Management of Lupus Anticoagulant Hypoprothrombinemia Syndrome in Juvenile Systemic Lupus Erythematosus – Single Center Experience
Abstract Number: 1044

Many Patients with Early Rheumatoid Arthritis Want Triple Therapy: An Analysis Combining Comparative Effectiveness Research and Patients Preferences to Inform Treatment Recommendations
Abstract Number: 779

Mapping Perceptions of Medication Decision Making Facilitators: The Importance of Patient Context
Abstract Number: 3143

Mapping the Back-Door Routes into the Vascular Wall: 3D Microscopic Reconstruction of Microvasculature in the Normal Temporal Artery and in Giant Cell Arteritis
Abstract Number: 1441

Marine Oil Supplements for Arthritis Pain: A Systematic Review and Meta-Analysis of Randomized Trials
Abstract Number: 1285

Markers of Non-Compliance with ASAS/EULAR Management Recommendations Among Early Spa Patients: Evidence over 3 Years in the DESIR Cohort
Abstract Number: 663

Mases Correlates Linearly with Disease Activity and Patient Related Outcomes in Patients with Axial Spondyloarthritis within the Scqm Cohort
Abstract Number: 360

Massive Elimination of Multinucleated Osteoclasts By Eupatilin Is Due to Dual Inhibition of Transcription and Cytoskeletal Rearrangement
Abstract Number: 200

Mast Cell Regulation of Aortic IL-6 Expression Involves Histamine-1 Receptor, Suppressor of Cyotkine Signaling-1 and IL-10
Abstract Number: 2999

Maternal Microchimerism Is Increased in Multiple Cellular Subsets of Patients with Systemic Sclerosis Compared to Healthy Controls
Abstract Number: 1101

Matrix Metalloproteinase-10 (Stromelysin 2) Is a Target of Robust Autoimmune T and B Cell Responses in Antibiotic-Refractory Lyme Arthritis, but Not in Rheumatoid Arthritis
Abstract Number: 293

Measurement of Advanced Glycation Endproducts in the Skin of Patients with Idiopathic Inflammatory Myopathies
Abstract Number: 2981

Measurement of Tissue Damage in Scleroderma Using Digital Mammographic Xrays: A Proof of Concept Study
Abstract Number: 649

Measures of Health-Related Quality of Life in Psoriatic Arthritis: Are They Sensitive to Both Joint and Skin Aspects?
Abstract Number: 1204

Measuring the Effectiveness of Patient Education of Patients Receiving Injectable Biologic Medications
Abstract Number: 1269

Measuring the Rheumatologist Workforce in Canada: Preliminary Results of the Stand up and be Counted Survey
Abstract Number: 1413

Medial Meniscus Extrusion and Spontaneous Osteonecrosis of the Knee
Abstract Number: 2426

Medication Taper and Risk of Relapse in Pediatric Uveitis
Abstract Number: 2515

MEK5/ERK5, a Lynchpin of Human Cardiac Fibroblast Transdifferentiation to a Scarring Phenotype in Autoimmune Congenital Heart Block
Abstract Number: 1841

Meningitis in Systemic Lupus Erythematosus Patients: Epidemiologic Profile of Listeria Monocytogenes Infection. a Single-Center Study
Abstract Number: 793

Mesenchymal Stem Cells Promote the Generation of CD206+ Macrophage and Increase Its Phagocytic Activity in Systemic Lupus Erythematosus
Abstract Number: 3180

Mesenchymal Stromal Cell Treatment in Juvenile Idiopathic Arthritis: A Pilot Study
Abstract Number: 507

Meta-Analysis of the Time Course of the Response to Adalimumab Plus Methotrexate or Methotrexate Monotherapy in Clinical Trials of Patients with Rheumatoid Arthritis
Abstract Number: 996

Metabolic Control of Invariant Natural Killer T Cell Function
Abstract Number: 2134

Metabolic Reprogramming in the Inflamed Joint Inhibits Pro-Inflammatory Mechanisms
Abstract Number: 1685

Metabolic Syndrome in Patients with Psoriatic Arthritis Is Associated to Peripheral Disease Activity
Abstract Number: 1584

Metabolic Syndrome Is Associated with Disease Activity in Patients with Rheumatoid Arthritis: A Prospective Cohort Study
Abstract Number: 2550

Metabolomic Profiling of Joints in Murine Models of Inflammatory Arthritis
Abstract Number: 574

Metabolomic Profiling Predicts Outcome of Rituximab Therapy in Rheumatoid Arthritis
Abstract Number: 2865

Methotrexate and Leflunomide Survival in Patients with Psoriatic Arthritis
Abstract Number: 579

Methotrexate Does Not Influence 1-Year Bone Mineral Density in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
Abstract Number: 2618

Methotrexate Dose May Associated with the Frequency of Lymphoproliferative Disorders in Rheumatoid Arthritis
Abstract Number: 2439

Methotrexate Failure in Pediatric Uveitis
Abstract Number: 1041

Methotrexate Monotherapy and Methotrexate Combination Therapy with Traditional and Biologic Dmards for Rheumatoid Arthritis: A Cochrane Systematic Review and Network Meta-Analysis
Abstract Number: 2724

Methotrexate Treatment Could Modulate the Abnormal CD4+T Lymphocyte Subset Distribution in NaÏve Rheumatoid Arthritis Patients
Abstract Number: 473

Methotrexate, Blood Pressure and Arterial Wave Reflection in Rheumatoid Arthritis
Abstract Number: 1247

Methylation Analysis of HLA-B Locus in Familial Behçet Syndrome
Abstract Number: 1950

Methylation-Dependent Interference of Two Promoters for the Treg-Specific Protein, Garp, Contributes to Altered Treg Function in Rheumatoid Arthritis
Abstract Number: 2998

Microchimerism Is Present in Systemic Sclerosis Lung and Includes CD31-Positive Cells
Abstract Number: 3044

Microparticles (MPs) Derived from Cell Plasma Membranes Are Increased in Behcet’s Syndrome (BS) and a Low Ratio of Tissue Factor Pathway Inhibitor Positive Mps to Tissue Factor Positive Mps (TFPI/TF) Is Associated with Thrombosis
Abstract Number: 2398

Microrna Biomarker Signature in Osteoarthritis
Abstract Number: 1026

Microrna-125a-5p Has Increased Expression in Active Systemic Juvenile Idiopathic Arthritis and Is an Essential Modulator of Regulatory Macrophage Phenotypes in Vitro
Abstract Number: 541

Microrna-125b Expression in PBMCs Is Associated with Disease Activity in Patients with Early Rheumatoid Arthritis
Abstract Number: 1133

Microrna-128 Interference Mitigates the Progression of Keen Osteoarthritis By Regulating Sirtuin-1
Abstract Number: 935

Microrna-146a Provides Feedback Regulation of Monosodium Urate-Induced Gouty Arthritis in Mice By Targeting Tumor Necrosis Factor Receptor Associated Factor 6 and Interleukin-1 Receptor-Associated Kinase 1
Abstract Number: 3153

Microrna-155/PU.1 Axis As an Epigenetic Regulator of B-Cells in Rheumatoid Arthritis
Abstract Number: 1945

microRNA-30a Promotes the Inflammatory Response of Rheumatoid Arthritis By Regulating Th1 Cell Differentiation
Abstract Number: 2060

Microscopic Bowel Inflammation in Spondyloarthritis As a Baseline Predictor of Anti-TNF Response
Abstract Number: 3067

Microscopic Colitis in Patients with Takayasu Arteritis; A Potential Association Between the Two Disease Entities
Abstract Number: 23

Microvesicle-Associated Hsa-Mir-223-3p Is Elevated in Rheumatoid Synovial Fluid Compared with Osteoarthritis Synovial Fluid
Abstract Number: 749

Microvesicles Containing Nucleic Acids and Expressing Immunoglobulins and HMGB1 Are Abundant in Patients with Systemic Lupus Erythematosus
Abstract Number: 2965

Might Troponin be a Marker for Subclinical Scleroderma Heart Involvement (SHI)?
Abstract Number: 2314

Minimal Important Difference in HAQ: A Validation from Health Economic Perspectives in Patient with Rheumatoid Arthritis Using Real-World Data
Abstract Number: 303

Mining RNA-Seq of Peripheral Blood Mononuclear Cells from JDM Alone Compared with JDM Plus Psoriasis for Biomarkers of Disease Activity
Abstract Number: 1168

MiR125a-5p Mediates Angiogenic Mechanisms in Inflammatory Arthritis
Abstract Number: 1765

MiR155 Deficient Mice Show Reduced Disease Severity in Pristane-Induced Lupus
Abstract Number: 2786

miR200b-5p: A Possible Predictor of Lymphoma Development in Sjögren’s Syndrome (SS)?
Abstract Number: 2135

miRNA-223 Delivery to Synovial Fibroblasts Via Monocyte-Derived Extracellular Vesicles Promotes Their Proliferation
Abstract Number: 682

Misalignment Between Physician and Patient Satisfaction with Current Psoriatic Arthritis Treatment
Abstract Number: 2298

Misdiagnosis of Fibromyalgia (FM) As Axial Spondylarthritis (SpA): Lessons from Analysis of 26 Cases
Abstract Number: 1666

Mitochondrial Haplogroups in Patients with Rheumatoid Arthritis with Respect to Biological Treatment
Abstract Number: 2072

Mitochondrial Reactive Oxygen Species Modulate Autoimmunity in Systemic Lupus Erythematosus
Abstract Number: 2073

Mitochondrial ROS Is a Novel Regulator of Sting-Mediated Type I IFN Production By Governing Extrusion of Oxidized Mitochondrial DNA upon Neutrophil Extracellular Trap Formation.
Abstract Number: 278

Mitral Valve Prolapse in Patients with Joint Hypermobility Syndrome
Abstract Number: 2319

Mobile Medical Documentation of Patient-Reported-Outcome
Abstract Number: 205

Mode of Action of Therapeutic Anti-Citrullinated Protein Antibodies Revealed: Inflammation Reduction Due to Inhibition of Netosis
Abstract Number: 845

Modelling of Longitudinal Changes in Lung Function in Patients with Systemic Sclerosis and Their Association with Development of Pulmonary Hypertension
Abstract Number: 2914

Modifiable and Non-Modifiable Correlates of Satisfaction with Care in Systemic Lupus Erythematosus
Abstract Number: 2025

Modification of Structural Lesions on Magnetic Resonance Imaging By Etanercept: A 12-Week Randomized Placebo-Controlled Trial
Abstract Number: 2846

Modifications to Biologic Therapy and Economic Implications in Psoriatic Arthritis Patients
Abstract Number: 1080

Modified Rodnan Skin Score Thresholds for the Optimization of Cohort Enrichment in Clinical Trials in Skin Fibrosis in Patients with Diffuse Cutaneous Systemic Sclerosis
Abstract Number: 1643

Modified-Release Formulation of Tofacitinib: Evaluation of Pharmacokinetics Compared with Immediate-Release Tofacitinib and Impact of Food
Abstract Number: 1751

Modulation of IRF4 Function Promotes Expansion of Effector Tregs in Lupus
Abstract Number: 1261

Molecular Analysis of Vascular Smooth Muscle Cells from Patients with Giant Cell Arteritis: Targeting Endothelin-1 Receptor to Control Proliferation
Abstract Number: 605

Monitoring of Epstein Barr Virus, Cytomegalovirus and Varicella Zooster Virus Load in Patients Receiving Tocilizumab for Rheumatoid Arthritis
Abstract Number: 2132

Monocarboxylate Transporter 4, Associated with the Acidification of Synovial Fluid, Is a Novel Therapeutic Target for Inflammatory Arthritis
Abstract Number: 1911

Monocyte Chemoattractant Protein-1 (MCP-1, CCL2) Is a Potential Local Marker of Renal Involvement in Scleroderma
Abstract Number: 422

Mood Disorder Is Highly Prevalent in a Multi-Ethnic Urban Pediatric Lupus Cohort
Abstract Number: 339

More Inflammatory Signs on Ultrasound, Severe Pain and Stiffness Are Associated with Erosive Than Non-Erosive Hand Osteoarthritis
Abstract Number: 1008

Morphometric Study of Algerian Hips: An Etiological Study to Explain the Low Prevalence of Hip Osteoarthritis in Algeria
Abstract Number: 2946

Mortality Among SLE Patients in the National Data Bank for Rheumatic Diseases
Abstract Number: 2158

Mortality Associated with Giant Cell Arteritis from 1980 to 2011: An Analysis of the French National Death Certificate Database
Abstract Number: 1343

Mortality Due to Sepsis in Patients with Rheumatoid Arthritis
Abstract Number: 60

Mortality of Systemic Lupus Erythematosus in Puerto Rico Assessed By Multiple-Cause-of-Death Analysis
Abstract Number: 2899

Mortality Related to Pediatric Systemic Lupus Erythematosus: A Multiple Cause-of-Death Analysis in France
Abstract Number: 1104

Mouse B Cells Require Glucose and Free Fatty Acids As Carbon Sources for Cytokine and Chemokine Secretion
Abstract Number: 465

MRI Bone Erosion at Baseline Predicts the Subsequent Radiographic Progression in Early-Stage RA Patients Who Achieved in Sustained Clinical Good Response: Sub-Analysis from Nagasaki University Early Arthritis Cohort
Abstract Number: 514

MRI Bone Oedema at Enrollment Predicts the Development of Rapid Radiographic Progression at 1 Year Toward Patients with Early-Stage Rheumatoid Arthritis: Results from Nagasaki University Early Arthritis Cohort
Abstract Number: 2030

MRI Changes Associated with Neurological Compromise in Acute Pyogenic Vertebral Osteomyelitis: A Retrospective Study of 121 Patients
Abstract Number: 1306

MRI Erosions in Undifferentiated Arthritis. Different Associations with the Collagen IIA N-Terminal Propeptide (PIIANP) and Galectin-3 in Pre-RA and Other Arthritides
Abstract Number: 1308

MRI Measures of Disease Activity and Joint Damage Are Associated with Patient-Reported Outcomes in Rheumatoid Arthritis
Abstract Number: 1727

MRI Vertebral Corner Inflammation Followed By Fat Deposition Is the Strongest Contributor to the Development of New Bone at the Same Vertebral Corner: A Multi-Level Longitudinal Analysis in Patients with Ankylosing Spondylitis
Abstract Number: 931

mTOR Complex 1 Signaling Is Required for the Steady-State in Vivo Development of Inflammatory Monocytes
Abstract Number: 687

Mucosal Dysregulation in First-Degree Relatives of Ankylosing Spondylitis Patients
Abstract Number: 1374

Mucosal-Associated Invariant T- Cells Are Decreased and Functionally Immature in Peripheral Blood of Patients with Primary Sjögren Syndrome
Abstract Number: 2594

Multi-Biomarker Disease Activity Score As a Predictor of Flare in Patients with Rheumatoid Arthritis Who Stop TNF-Alpha-Inhibitor Therapy
Abstract Number: 746

Multi-Center Delphi Exercise Reveals Important Key Items in Classifying SLE
Abstract Number: 2820

Multi-Omics Studies of Gut Microbiota in Enthesitis-Related Arthritis Identify Diminished Microbial Diversity and Altered Typtophan Metabolism As Potential Factors in Disease Pathogenesis
Abstract Number: 1350

Multi-Targeted Loop-Mediated Isothermal Amplification for Rapid Diagnosis of Osteoarticular Tuberculosis in 60 Minutes: Experience from North India
Abstract Number: 538

Multidrug Resistant Lymphocytes of Patients with Rheumatoid Arthritis Are Predictive for DMARD and Glucocorticoid Treatment Response
Abstract Number: 2638

Multiple Psychosocial Factors Influence Subjective Assessments of Disease Activity in Rheumatoid Arthritis
Abstract Number: 253

Multiple Serum Cytokine Profiling to Identify Specific Molecular Networks in Attacks of Familial Mediterranean Fever
Abstract Number: 3264

Multiplex Serum Protein Analysis in Systemic Sclerosis Defines Potential Anti-Fibrotic Mechanisms and Markers of Response to Hyperimmune Caprine Serum
Abstract Number: 2699

Muscle Inflammation Relates to Disease Activity and Disability but Not Insulin Resistance in Rheumatoid Arthritis
Abstract Number: 1398

Musculoskeletal and Serologic Findings in an Adult Cystic Fibrosis Clinic Population-a Systematic Review and Collation with Disease Status
Abstract Number: 1465

Musculoskeletal Anomalies in Children with Trisomy 21
Abstract Number: 1833

Musculoskeletal Complications of Systemic Lupus Erythematosus: Risk Factors for and Prevalence of Avascular Necrosis and Osteoporosis
Abstract Number: 2967

Musculoskeletal Involvement in SSc Correlates with Poor Short Form 36 and SSc Health Assessment Questionnaire Scores As Well As Lower TNF-Alpha Gene Expression in PBMCs
Abstract Number: 925

Musculoskeletal Ultrasound (MSK-US): Innovation or Overutilization?
Abstract Number: 1186

Musculoskeletal Ultrasound Education Among Rheumatology Fellowship Programs in the United States
Abstract Number: 2691

Musculoskeletal Ultrasound in Multi-Center Rheumatoid Arthritis Clinical Trials: Methodology for Optimizing Reliability of Acquisition and Real-Time Scoring
Abstract Number: 831

Mycophenolate Decreases the Frequency of Endoscopic Therapy for Gastric Antral Vascular Ectasia in Patients with Systemic Sclerosis
Abstract Number: 2985

Mycophenolate Mofetil (MMF) Use in Systemic Sclerosis (SSc) Patients with a Designation of Elevated Systolic Pulmonary Artery Pressure (sPAP): Forced Vital Capacity (FVC), Outcomes and Survival from the European Scleroderma Trials and Research (EUSTAR) Database
Abstract Number: 2378

Mycophenolate Mofetil As a Steroid Sparing Agent in Polymyositis and Dermatomyositis: a Systematic Review of the Literature
Abstract Number: 724

Mycophenolate Mofetil in Non-Renal Manifestations of Systemic Lupus Erythematosus. an Observational Cohort Study
Abstract Number: 1790

Mycophenolate Mofetil Suppresses Humoral Response to Pneumococcal Vaccine in Patients with Systemic Lupus Erythematosus and Other Autoimmune Diseases
Abstract Number: 1886

Myocardial Fibrosis Detected By Magnetic Resonance Imaging Is a Predictor of Heart Failure in Systemic Sclerosis (SSc) Patients
Abstract Number: 1817

Myocardial Tissue Characterization with Native Myocardial T1 Mapping in SLE Patients with Chest Pain
Abstract Number: 288

Myositis Associated Interstitial Lung Disease: Clinical Predictors of Failure to Conventional Treatment and Their Response to Tacrolimus
Abstract Number: 2368

Myositis Specific-Autoantibodies: Predictors of Short-Term Good Outcome in Rituximab Treated-Refractory Idiopathic Inflammatory Myopathies