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  • Abstract Number: 744 • 2019 ACR/ARP Annual Meeting

    Are Hematologic Indexes Helpful in the Diagnosis and Prognosis of Polymyalgia Rheumatica?

    María de la Torre1 and Cecilia Pisoni 1, 1Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno (CEMIC), Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina

    Background/Purpose: Recently, the use of hematologic indexes as markers of systemic inflammation has been reported in oncological, cardiovascular and rheumatic diseases. Only 2 studies evaluated…
  • Abstract Number: 745 • 2019 ACR/ARP Annual Meeting

    Cardiac Involvements Are Related to Poor Prognosis in Patients with Takayasu’s Arteritis in China

    Yujiao Wang1, Lili Ma 1, Yan Yan 2, Ying Sun 3, Yongshi Wang 4, Xiaomin Dai 1, Zongfei Ji 5, Lingying Ma 1, Huiyong Chen 3 and Lindi Jiang 1, 1Zhongshan Hospital, Fudan University, Shanghai, China (People's Republic), 2Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, P. R. China, Shanghai, China (People's Republic), 3Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, P. R. China, Shanghai, 4Department of Echocardiography, Zhongshan Hospital, Fudan University, Shanghai, P. R. China, Shanghai, 5Department of Rheumatology, Zhongshan hospital, Fudan University, Shanghai, China (People's Republic)

    Background/Purpose: Heart involvements are closely associated with prognosis in patients with Takayasu’s arteritis (TA). This study was aimed to assess the long-term adverse outcomes of…
  • Abstract Number: 746 • 2019 ACR/ARP Annual Meeting

    Childhood-Onset Takayasu’s Arteritis (TAK) Is Clinically More Active, However Has Similar Cumulative Damage Compared to Adult-Onset TAK

    Murat Karabacak1, Sema Kaymaz-Tahra 2, Sezgin Sahin 3, Mehmet Yıldız 4, Amra Adrovic 5, Kenan Barut 6, Haner Direskeneli 7, Ozgur Kasapcopur 8 and Fatma Alibaz-Oner 1, 1Marmara University Faculty of Medicine,Department of Rheumatology,Istanbul,Turkey, Istanbul, Turkey, 2Marmara University School of Medicine, Division of Rheumatology, Istanbul, Istanbul, Turkey, 3Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Istanbul, Turkey, 4Department of Pediatric Rheumatology, Istanbul University Cerrahpasa, Istanbul, Istanbul, Turkey, 5Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Turkey, 6Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, İstanbul, Istanbul, Turkey, 7Marmara University, School of Medicine, Division of Rheumatology, Istanbul, Turkey, 8Department of Pediatric Rheumatology, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Turkey

    Background/Purpose: Childhood-onset Takayasu’s Arteritis (TAK) may differ in presentation, clinical manifestations and treatment, as previously shown1. We aimed to compare the clinical manifestations, vascular involvement…
  • Abstract Number: 747 • 2019 ACR/ARP Annual Meeting

    Detrimental Factors Affecting the First-year Clinical Response in Korean Patients with Polymyalgia Rheumatica

    Yoon-Jeong Oh 1, Seung Min Jung 2, Byoong Yong Choi 3 and Kichul Shin4, 1Kanwon National University Hospital, Chuncheon, Republic of Korea, 2Yonsei university college of medicine, severance hospital, Seodaemun-gu, Republic of Korea, 3Seoul Medical Center, Seoul, Republic of Korea, 4Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea., seoul, Republic of Korea

    Background/Purpose: Polymyalgia rheumatica (PMR) is a chronic inflammatory disease in which patients respond well to glucocorticoids (GCs). However, a number of patients experience a flare…
  • Abstract Number: 748 • 2019 ACR/ARP Annual Meeting

    Takayasu Arteritis and Sacroiliitis: A Case Control Study in 28 Patients of a Single Italian Center

    Paola Toniati1, Francesca Regola 1, Franco Franceschini 1, Giovanni Bosio 2 and Angela Tincani 3, 1Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy, Brescia, Italy, 2Nuclear Medicine Unit, ASST Spedali Civili of Brescia, Brescia, Italy, Brescia, Italy, 3Rheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy, Brescia, Italy

    Background/Purpose: A lot of clinical case descriptions about spondyloarthropathy in TAK patients were reported. Recently, a paper about an increased incidence of spondyloarthropathy in TAK…
  • Abstract Number: 749 • 2019 ACR/ARP Annual Meeting

    Childhood Takayasu Arteritis: Characteristics and Outcomes of a Mexican Cohort

    Grissell Alejandra Valero-Gaona1, Enrique Faugier-Fuentes 2 and Angélica Vargas Guerrero 3, 1Departamento de Reumatología, Instituto Nacional de Cardiología "Ignacio Chávez", Ecatepec, Distrito Federal, Mexico, 2Department of Rheumatology, Hospital Infantil de México Federico Gómez, Mexico City, Mexico, 3Departamento de Reumatología del Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico

    Background/Purpose: Takayasu arteritis (TA) is a large vessel vasculitis that affects aorta and its main branches. Despite being the third most common vasculitis in childhood,…
  • Abstract Number: 750 • 2019 ACR/ARP Annual Meeting

    Extravascular Inflammatory Manifestations of Takayasu Arteritis in a Monocentric Cohort

    Elena Baldissera1, Alessandro Tomelleri 1, Silvia Sartorelli 2, Corrado Campochiaro 3 and Lorenzo Dagna 1, 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases. IRCCS San Raffaele Hospital. Vita-Salute San Raffaele University., Milan, Italy, 2Vita-Salute San Raffaele University, IRCCS San Raffaele Hospital, Milan, Italy, 3Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy

    Background/Purpose: Takayasu arteritis (TAK) is an inflammatory disease which primarily affects large vessels. However, as a systemic disease, the spectrum of its manifestations is not…
  • Abstract Number: 751 • 2019 ACR/ARP Annual Meeting

    Pregnancy Outcome in Patients with Takayasu Arteritis: The Results of Turkish Takayasu Study Group

    Nilufer Alpay-Kanitez 1, Sema Kaymaz-Tahra 2, Ayten Yazici 3, Ayse Cefle 4, Mete Kara 5, Handan Yarkan-Tugsal 6, Onay Gercik 7, Servet Akar 8, Fatos Onen 9, Kenan Aksu 10, Gokhan Keser 5, Cemal Bes 11, Sevil Kamalı 12, Fatma Alibaz-Oner 13 and Haner Direskeneli14, 1Koc University School of Medicine, Division of Rheumatology, İstanbul, Turkey, 2Marmara University School of Medicine, Division of Rheumatology, Istanbul, Istanbul, Turkey, 3Kocaeli University, Faculty of Medicine, Division of Rheumatology, Kocaeli, Kocaeli, Turkey, 4Kocaeli University, Faculty of Medicine, Division of Rheumatology, Kocaeli, Turkey, 5Ege University School of Medicine, Division of Rheumatology, Izmir, Turkey, 6Dokuz Eylul University School of Medicine, Division of Rheumatology, Izmir, Turkey, 7Izmir Katip Celebi University, Faculty of Medicine, Division of Rheumatology, Izmir, Turkey, 8Izmir Katip Celebi University, Faculty of Medicine, Division of Rheumatology, İzmir, Turkey, 9Dokuz Eylul University School of Medicine, Division of Rheumatology, İzmir, Turkey, 10Ege University, Department of Internal Medicine, Division of Rheumatology, Izmir, 11University of Medical Sciences, İstanbul, Turkey, 12Private office, İstanbul, Turkey, 13Marmara University Faculty of Medicine,Department of Rheumatology,Istanbul,Turkey, Istanbul, Turkey, 14Marmara University, School of Medicine, Division of Rheumatology, Istanbul, Turkey

    Background/Purpose: Takayasu's arteritis (TAK) is a large vessel vasculitis of the young women in their reproductive age. According to our previous report from single center…
  • Abstract Number: 752 • 2019 ACR/ARP Annual Meeting

    Drug Retention and Discontinuation Reasons Between Seven Biologics in Patients with Takayasu Arteritis

    Corrado Campochiaro1, Alessandro Tomelleri 2, Silvia Sartorelli 3, Giulio Cavalli 2, De Luca Giacomo 4, Elena Baldissera 2 and Lorenzo Dagna 2, 1Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy, 2Unit of Immunology, Rheumatology, Allergy and Rare Diseases. IRCCS San Raffaele Hospital. Vita-Salute San Raffaele University., Milan, Italy, 3Vita-Salute San Raffaele University, IRCCS San Raffaele Hospital, Milan, Italy, 4Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy., Milan, Italy

    Background/Purpose: Takayasu's arteritis (TA) is a large vessel vasculitis affecting mainly young women. Biologic agents are currently use to treat refractory TA patients but no…
  • Abstract Number: 753 • 2019 ACR/ARP Annual Meeting

    Initial Clinical Presentation Is Associated with Outcome in Takayasu’s Arteritis

    Kaitlin Quinn1, K Bates Gribbons 2, Elaine Novakovich 3 and Peter C. Grayson 4, 1Georgetown University Hospital/National Institutes of Health, Washington, DC, 2National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 3National Institutes of Health, Bethesda, MD, 4National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD

    Background/Purpose: The natural history of Takayasu’s arteritis (TAK) remains poorly characterized.  A “triphasic” pattern of disease has been proposed where constitutional symptoms precede vascular inflammation…
  • Abstract Number: 754 • 2019 ACR/ARP Annual Meeting

    Dynamic Distribution and Phenotype Shift from M1 to M2 of Macrophages in Vascular Lesions of Naïve and Treated Patients with Takayasu Arteritis

    Xiufang Kong1, Ming Xu 2, Xiaomeng Cui 2, Lingying Ma 2, Huiyong Chen 3, Lili Ma 2 and Lindi Jiang 2, 1University of Michigan & Fudan University, Ann Arbor, MI, 2Zhongshan Hospital, Fudan University, Shanghai, China (People's Republic), 3Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, P. R. China, Shanghai

    Background/Purpose: Takayasu arteritis (TA) is a chronic inflammatory disease characterized by arterial vascular fibrosis. Type I (M1) and type II (M2) macrophages play very important…
  • Abstract Number: 755 • 2019 ACR/ARP Annual Meeting

    A Novel Diagnostic Algorithm for Polymyalgia Rheumatica Using Three Musculoskeletal Sites on Whole Body PET/CT

    Claire Owen1, Aurora Poon 1, Victor Yang 1, Chris McMaster 1, Sze Ting Lee 1, David Liew 1, Jessica Leung 1, Andrew Scott 1 and Russell Buchanan 1, 1Austin Health, Heidelberg, Victoria, Australia

    Background/Purpose: PMR is associated with a pattern of abnormal 18F-Fluorodeoxyglucose (18F-FDG) uptake on whole body PET/CT that is increasingly recognised to correlate anatomically with inflammation…
  • Abstract Number: 756 • 2019 ACR/ARP Annual Meeting

    A Volar Pattern of 18F-Fluorodeoxyglucose Uptake at the Hand on Whole Body PET/CT Predicts Glucocorticoid-Responsive Disease in Polymyalgia Rheumatica

    Claire Owen1, Aurora Poon 1, Sze Ting Lee 1, Chris McMaster 1, Jessica Leung 1, David Liew 1, Andrew Scott 1 and Russell Buchanan 1, 1Austin Health, Heidelberg, Victoria, Australia

    Background/Purpose: Almost half of all patients diagnosed with PMR require a protracted duration of glucocorticoid therapy due to relapsing disease.(1) On whole body PET/CT, PMR…
  • Abstract Number: 757 • 2019 ACR/ARP Annual Meeting

    Long-term Clinical Course and Outcomes of 2013 Patients with Takayasu Arteritis

    Hajime Yoshifuji1, Haruhito Uchida 2, Yoshikazu Nakaoka 3, Takahiko Sugihara 4, Mitsuaki Isobe 5 and Masayoshi Harigai 6, 1Kyoto University, Kyoto, Japan, 2Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan, 3National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan, 4Tokyo Medical and Dental University, Tokyo, Japan, 5Sakakibara Heart Institute, Tokyo, Japan, 6Department of Rheumatology, Tokyo Women's Medical University School of Medicine, Shinjuku-ku, Tokyo, Japan

    Background/Purpose: Takayasu arteritis (TAK) occurs at a young age and has a long-term clinical course. Progression of arterial stenosis or dilatation leads to organ dysfunction.…
  • Abstract Number: 758 • 2019 ACR/ARP Annual Meeting

    Interleukin-6 May Predict Disease Relapse During Long-term Follow-up in Takayasu’s Arteritis in a Han Chinese Population

    Ying Sun1, Kong Xiufang 2 and Lindi Jiang 3, 1Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, P. R. China, Shanghai, 2Zhongshan Hospital Fudan University, ShangHai, China (People's Republic), 3Zhongshan hospital, Fudan University, Shanghai, China (People's Republic)

    Background/Purpose:  To evaluate the role of interleukin-6 (IL-6) in predictinglong-term disease prognosis for Takayasu’s arteritis (TA).Methods: Thirty-one patients diagnosed with TA between January 2012 and…
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