Abstract Number: 403 • 2014 ACR/ARHP Annual Meeting
Metaflammation, PEDF and Chemerin: Potential Systemic Factors Which Link Obesity to Response to Therapy in Early Rheumatoid Arthritis
Background/Purpose . Obesity per se is a systemic, low-grade inflammatory state and the adipose tissue is an endocrine organ that releases bioactive substances, including pro-inflammatory…Abstract Number: 402 • 2014 ACR/ARHP Annual Meeting
Can GP88 (Progranulin) be Used As a Biomarker for the Diagnosis and Therapy Evaluation of Rheumatoid Arthritis?
Background/Purpose GP88 (progranulin; PGRN), a glycoprotein with a molecular weight of approximately 88000, is suggested to play an important role in the immune response and…Abstract Number: 401 • 2014 ACR/ARHP Annual Meeting
Association of Anti-Thyroid Autoantibodies with Fibromyalgia in Rheumatoid Arthritis
Background/Purpose Autoimmune thyroiditis has been linked independently with fibromyalgia and chronic widespread pain. We studied how the presence of autoimmune thyroiditis affects the clinical presentation…Abstract Number: 400 • 2014 ACR/ARHP Annual Meeting
Clinical Utility of 14-3-3η in the Evaluation of Inflammatory Arthritis
Background/Purpose 14-3-3 proteins are chaperonins found in all eukaryotic cells. There are multiple isoforms which are thought to be involved in intracellular signaling and transcription…Abstract Number: 399 • 2014 ACR/ARHP Annual Meeting
Lipid Concentrations and Particle Sizes in Drug Naive Patients with Rheumatoid Arthritis
Background/Purpose Excess mortality attributed to cardiovascular causes has been described among patients with rheumatoid arthritis (RA). Atherosclerotic lipid profile has been reported in patients with…Abstract Number: 418 • 2014 ACR/ARHP Annual Meeting
Prevalence of Morning Stiffness in a US Registry Population of Rheumatoid Arthritis Patients
Background/Purpose : Morning stiffness is a symptom of rheumatoid arthritis (RA) that is frequently reported and thought to reflect disease activity, but its etiology is…Abstract Number: 417 • 2014 ACR/ARHP Annual Meeting
Normal Scores of “0” (floor effects) Are Seen in 33-83% of Patients with Rheumatoid Arthritis (RA) on 8 HAQ Activities Which Also Are Found on the MDHAQ, but in Fewer Than 32% of Patients on 2 Unique MDHAQ Complex Activities “Walk 2 Miles or 3 Kilometers,” and “Participate in Recreation and Sports.”
Background/Purpose: Patients with rheumatoid arthritis (RA) have significantly better clinical status in recent years compared with previous decades.1 Health assessment questionnaire (HAQ) scores were almost…Abstract Number: 416 • 2014 ACR/ARHP Annual Meeting
Using Patient Reported Outcome Measures to Classify Disease Activity States in Rheumatoid Arthritis: A Comparison of Patient-Derived Versions of Clinical Disease Activity Index (CDAI), Simplified Disease Activity Index (SDAI) and Disease Activity Score 28 (DAS28)
Background/PurposeIn RA the target for treatment is clinical remission or minimal disease activity. Patient self- monitoring of disease activity may enhance treatment by providing early…Abstract Number: 415 • 2014 ACR/ARHP Annual Meeting
a Dual-Center, Double Blind Randomized Study for a New Scientific Approach in Assessment of Tender Joints in Inflammatory Arthritis Using the Smart Joint Assessor Glove Device (Smart JAG Device)
Background/Purpose Tender Joint Count (TJC) is a vital quality measure to assess the progression of Inflammatory Arthritis both from a therapeutic and a diagnostic standpoint.…Abstract Number: 414 • 2014 ACR/ARHP Annual Meeting
Relationship Between Range of Motion of Joints in Upper Limbs and Physical Function in Patients with Long-Standing Rheumatoid Arthritis: Multicenter Prospective Cohort Study for Evaluation of Joint Surgery on Physical Function
Background/Purpose Even now, in clinical practice, most of RA patients have long-standing disease and structural damage in their joints. Reconstructive joint surgery should be needed…Abstract Number: 413 • 2014 ACR/ARHP Annual Meeting
Association of Antinuclear Antibodies with Lung Disease, Malignancy and Joint Replacement in Rheumatoid Arthritis
Background/Purpose Antinuclear antibodies (ANAs) are present in a significant proportion of patients with rheumatoid arthritis (RA). Positivity for ANA in RA has been associated with…Abstract Number: 411 • 2014 ACR/ARHP Annual Meeting
ABCB1 and ABCG2 Drug-Efflux Transporters Function and Its Association with Disease Activity in a Cohort of Patients with Rheumatoid Arthritis
Background/Purpose ABCB1 (P-gp) and ABCG2 (BCRP) are part of the adenine triphosphate (ATP)-binding cassette (ABC) transporter proteins. These proteins mediate efflux of drugs from inside…Abstract Number: 412 • 2014 ACR/ARHP Annual Meeting
Determinants of Radiological Progression in Rheumatoid Arthritis: Relationship with Serum Levels of OPG, RANKL and DKK-1
Background/Purpose: Osteoprotegerin (OPG), RANKL, and DKK-1 act as regulators of bone resorption and formation. The uncoupling of bone remodelling that occurs in rheumatoid arthritis (RA)…Abstract Number: 410 • 2014 ACR/ARHP Annual Meeting
Vascular Endothelial Function Changes during Treatment in Patients with Rheumatoid Arthritis
Background/Purpose: Rheumatoid Artrhitis (RA) patients have an increased risk for accelerated atherosclerosis. Endothelial dysfunction and arterial stiffness, assessed by measurement of carotid-femoral pulse wave velocity…Abstract Number: 409 • 2014 ACR/ARHP Annual Meeting
Soluble CD163 Is a Marker of Disease Activity in Early Rheumatoid Arthritis and Reflects TNFα Levels
Background/Purpose Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation and eventually destruction, where TNFa is a central mediator of both processes.…
ACR Meeting Abstracts