Abstracts Archive - Page 2206 of 2605 - ACR Meeting Abstracts

Abstract Number: 393 • 2014 ACR/ARHP Annual Meeting
Influence of Body Mass Index on Disease Activity and Radiographic Joint Damage in Rheumatoid Arthritis : A Systematic Review and Meta-Analysis
Celine Vidal¹, Thomas Barnetche², Jacques Morel³, Bernard Combe⁴ and Claire Daien⁵, ¹Rheumatology, Hopital Lapeyronie, Montpellier, France, ²rheumatology, Rheumatology department, Bordeaux University Hospital, bordeaux, France, ³Department of Rheumatology, Hôpital Lapeyronie, Montpellier, France, ⁴Immuno-Rhumatologie, Hôpital Lapeyronie, Montpellier, France, ⁵Hopital Lapeyronie, Montpellier, France
Background/Purpose: Overweight and obesity in patients with rheumatoid arthritis (RA) are rising conditions. Adipose tissue has pro inflammatory properties by producing adipokines which could play…
Abstract Number: 392 • 2014 ACR/ARHP Annual Meeting
Neuroendocrine Hormone and Metabolic Peptide Levels in the Earliest Phases of Rheumatoid Arthritis – Do Free Fatty Acids Play a Role?
Man Wai Tang¹, Frieda A. Koopman², Jan P.M. Visscher², Marjolein J.H. de Hair², Danielle M. Gerlag^2,3 and Paul P. Tak^2,4, ¹Division of Clinical Immunology and Rheumatology & Department of Experimental Immunology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands, ²Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ³GlaxoSmithKline, Cambridge, United Kingdom, ⁴University of Cambridge, Cambridge and GlaxoSmithKline, Stevenage, United Kingdom
Background/Purpose: Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with several neuroendocrine hormones and metabolic peptides. The crosstalk between the hormones and the immune…
Abstract Number: 391 • 2014 ACR/ARHP Annual Meeting
Self-Assessment Tool of Rheumatoid Arthritis Disease Activity: Handgrip Strength Measured By a Smartphone Connected to a Dynamometer
Francisco Espinoza Sr.¹, Yves-marie Pers Sr.², Pierre LeBlay Sr.² and Christian Jorgensen², ¹Rheumatology Department, Division of Internal Medicine, School of Medicine, University of Los Andes, Santiago, Chile, ²Clinical Immunology and Osteoarticular Diseases Therapeutic Unit, CHU Lapeyronie., Montpellier, France
Background/Purpose Patient self-management should become a key component of rheumatology care. Development of modalities using personal technologies resources represents an attractive way to assess periodic…
Abstract Number: 390 • 2014 ACR/ARHP Annual Meeting
Prevalence and Correlates of Patient-Physician Discordance in Early Rheumatoid Arthritis
John M. Davis III¹, Cynthia S. Crowson², Tim Bongartz¹, Clement J. Michet¹, Eric L. Matteson¹ and Sherine E. Gabriel³, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Health Sciences Research, Mayo Clinic, Rochester, MN, ³Health Sciences Research & Div of Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose Patients with rheumatoid arthritis (RA) sometimes rate their global disease activity differently than their rheumatologists. Previous studies describing this ‘discordance’ have primarily included patients…
Abstract Number: 389 • 2014 ACR/ARHP Annual Meeting
High 11B-HSD1 Activity Is Associated with Progression to Rheumatoid Arthritis in Patients with a New Onset of Inflammatory Arthritis
Dominika Nanus¹, Andrew Filer², Lorraine Yeo¹, Dagmar Scheel-Toellner³, Rowan Hardy⁴, Gareth Lavery⁵, Paul Stewart⁶, Christopher Buckley⁷, Mark Cooper⁸ and Karim Raza¹, ¹Rheumatology Research Group, University of Birmingham, Birmingham, United Kingdom, ²Rheumatology Research Group, MRC Centre for Immune Regulation, School of Immunity and Infection, University of Birmingham, Birmingham, United Kingdom, ³Rheumatology Research Group, Centre for Translational Inflammation Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK, Birmingham, United Kingdom, ⁴Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Birmingham, United Kingdom, ⁵Centre for Endocrinology, Diabetes and Metabolism,, University of Birmingham, Birmingham, United Kingdom, ⁶University of Leeds, Leeds, United Kingdom, ⁷Rheumathology Research Group, University of Birmingham, Birmingham, United Kingdom, ⁸University of Sydney, ANZAC Research Institute, Sydney, Australia
Background/Purpose Inadequate endogenous glucocorticoid (GC) synthesis during inflammation has been proposed as an aetiological factor in the development of rheumatoid arthritis (RA). It has been…
Abstract Number: 388 • 2014 ACR/ARHP Annual Meeting
Soluble TREM-1 Is a Biomarker of Anti-CCP-Positive, DMARD-Naive Early Rheumatoid Arthritis
Shachaf Ofer-Shiber¹, Elisheva Pokroy-Shapira², Yair Molad^3,4, Shirly Oren², Hagit Shay-Aharoni² and Ilan Babai⁵, ¹Department of Internal Medicine H, Rabin Medical Center, Beilinson Hospital and Sackler Faculty of Medicine, Tel Aviv University, Petach Tikva, Israel, ²Rheumatology Unit, Rabin Medical Center, Beilinson Hospital and Sackler Faculty of Medicine, Tel Aviv University, Petach Tikva, Israel, ³Rheumatology Unit, Rabin Medical Center, Beilinson Hospital and Sackler Faculty of Medicine, Tel Aviv University, Petah Teqva, Israel, ⁴Laboratory of Inflammation Research, Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Petach Tikva, Israel, ⁵Laboratory of Clinical Immunology, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel
Background/Purpose : Triggering receptor expressed on myeloid cells-1 (TREM-1) is a cell-surface receptor, expressed mainly on monocytes and neutrophils and involved in amplification of the inflammatory…
Abstract Number: 387 • 2014 ACR/ARHP Annual Meeting
Levels of IgG Autoantibodies to Oxidation-Associated MDA Neo-Determinants Are a Biomarker for Systemic Inflammation and Disease Activity in SLE and RA
Caroline Grönwall¹, Lelise Getu², Jeffrey D. Greenberg³, Robert M. Clancy⁴ and Gregg J. Silverman¹, ¹Medicine, New York University School of Medicine, New York, NY, ²New York University School of Medicine, New York, NY, ³Rheumatology, New York University School of Medicine, New York, NY, ⁴Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY
Background/Purpose Monitoring disease activity in patients with autoimmune rheumatic disease is an essential part of clinical care. Highly reactive malondialdehyde (MDA) arise from reactive oxygen…
Abstract Number: 386 • 2014 ACR/ARHP Annual Meeting
Association of Pharmacogenetic Markers with Treatment Response in Patients with Rheumatoid Arthritis
Ute I. Schwarz¹, Janet E. Pope², Edward Keystone³, Boulos Haraoui⁴, Carter Thorne⁵, Yun-Hee Choi¹, Melanie Poulin-Costello⁶, Nabil Bayan⁷ and Richard B. Kim¹, ¹Western University, London, ON, Canada, ²Medicine, Western University, London, ON, Canada, ³Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁴University of Montreal Hospital Centre, Montreal, QC, Canada, ⁵Southlake Regional Health Centre, Newmarket, ON, Canada, ⁶Biostatistics, Amgen Canada Inc., Mississauga, ON, Canada, ⁷Amgen Canada Inc., Mississauga, ON, Canada
Background/Purpose : In the CAnadian Methotrexate and Etanercept Outcome Study (CAMEO) continued therapy with etanercept (ETN) and methotrexate (MTX) led to better outcomes at month…
Abstract Number: 385 • 2014 ACR/ARHP Annual Meeting
Validation of a Prognostic Model to Predict Structural Damage Assessed By X-Ray in Patients with RA Using MRI Data from a Clinical Trial
EA Alemao¹, S Joo², S Banerjee¹, P Allison³, P Emery⁴, M Weinblatt⁵ and Katherine Liao⁶, ¹Bristol-Myers Squibb, Princeton, NJ, ²Bristol-Myers Squibb, Hopewell, NJ, ³University of Pennsylvania, Philadelphia, PA, ⁴University of Leeds, Leeds, United Kingdom, ⁵Brigham and Women's Hospital, Boston, MA, ⁶Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA
Background/Purpose: We developed and validated a prognostic model for rapid radiographic progression (RRP) using X-ray data to identify RA patients (pts) at risk of structural…
Abstract Number: 380 • 2014 ACR/ARHP Annual Meeting
In Palindromic Rheumatism, Older Age, Shorter Interval Between Attacks and Positive Anti-CCP Antibodies May Predict Progression to RA
Masatoshi Hayashi^1,2, Jackie L. Nam³, Laura Hunt³, Elizabeth Hensor³, Toshihisa Kanamono⁴, Toshihisa Kojima⁵, Naoki Ishiguro⁵ and Paul Emery⁶, ¹NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds., Leeds, United Kingdom, ²5-22-1 Wakasato, Nagano Red Cross Hospital, Nagano, Japan, ³NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁴Departments of Orthopedic surgery and Rheumatology, Nagano Red Cross Hospital, Nagano, Japan, ⁵Orthopaedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan, ⁶NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds., United Kingdom, Leeds, United Kingdom
Background/Purpose Palindromic rheumatism (PR) is a clinical syndrome characterised by episodes of joint swelling that settle spontaneously. A proportion of patients with PR progress and…
Abstract Number: 370 • 2014 ACR/ARHP Annual Meeting
Double Positivity of RA Serologies More Prevalent Yet Associated with Clinical Response in Ethnic Minority Patients with Rheumatoid Arthritis
Mercedes Quinones¹, Sharon Dowell², Ignacio Garcia-Valladares³, Gail S. Kerr⁴, Christopher Swearingen⁵, Luis R. Espinoza⁶, Yusuf Yazici⁷, Edward L. Treadwell⁸, Theresa Lawrence Ford⁹, Yvonne Sherrer¹⁰, Angelia Mosley-WIlliams¹¹, Rodolfo Perez Alamino¹², Chunqiao Luo¹³, Akgun Ince¹⁴, Adrian Godoy² and John Amatruda¹⁵, ¹Division of Rheumatology, Howard University Hospital, Washington, DC, ²Division of Rheumatology, Howard University, Washington, DC, ³Immunology and Rheumatology, Hospital General de Occidente, Zapopan, Jal., Mexico, ⁴Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, ⁵Pediatrics and Biostatistics, University of Arkansas, Little Rock, AR, ⁶Medicine-Section of Rheum, LSU Medical Center, New Orleans, LA, ⁷Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ⁸Dept Medicine Div of Rheum, East Carolina University, Greenville, NC, ⁹North Georgia Rheumatology Group, PC, Lawrenceville, GA, ¹⁰Rheum/Immunology, Centre Rheum Immunol Arthritis, Fort Lauderdale, FL, ¹¹Rheumatology, Detroit VAMC, Detroit, MI, ¹²internal Medicine, LSUHSC, New Orleans, LA, ¹³University of Arkansas for Medical Sciences, Little Rock, AR, ¹⁴Arthitis Consultants Inc, St. Louis University, St. Louis, MO, ¹⁵Rheumatology, Howard University, Washington, DC
Double Positivity of RA Serologies More Prevalent But Associated with Clinical Response in a Diverse Ethnic Cohort with Rheumatoid ArthritisBackground/Purpose: The presence of both the…
Abstract Number: 369 • 2014 ACR/ARHP Annual Meeting
Validation of Snapshot, a Rheumatoid Arthritis Assessment Tool, Against CDAI, DAS28 (ESR), and DAS28 (CRP) in Canadian Patients with Rheumatoid Arthritis
William G Bensen¹, Wynn Bensen², Melissa Deamude², Cynthia Mech³, Robert Bensen⁴, Arthur N. Lau⁵ and Alpesh Shah⁶, ¹St Josephs Hospital and McMaster University, Hamilton, ON, Canada, ²Dr William G Bensen Medicine Professional Corp, Rheumatology Health Team, Dr. Bensen's Rheumatology Clinic, Hamilton, ON, Canada, ³Dr. William G. Bensen, Rheumatology Health Team, Dr. Bensen's Rheumatology Clinic, Hamilton, ON, Canada, ⁴Rheumatology Health Team, Dr. Bensen's Rheumatology Clinic, Hamilton, ON, Canada, ⁵Rheumatology and Clinical Epidemiology, Division of Rheumatology, McMaster University, Hamilton, ON, Canada, ⁶Epidemiology and Biostatistics, University of Western Ontario, MSc in Clinical Epidemiology, University of Western Ontario, London, ON, Canada
Background/Purpose: Measuring disease activity in Rheumatoid Arthritis (RA) remains an elusive goal. Both DAS and CDAI have an inherent weakness because similar numbers can result…
Abstract Number: 368 • 2014 ACR/ARHP Annual Meeting
Serum C1M Level Predicts Disease Progression and Early Treatment Efficacy in Rheumatoid Arthritis
Anne C. Bay-Jensen¹, Anne Sofie Siebuhr², Inger Byrjalsen³, Claus Christiansen³ and Morten Asser Karsdal¹, ¹Nordic Bioscience, Biomarkers and Research, Herlev, Denmark, ²Rheumatology, Nordic Bioscience, Biomarkers and Research, Herlev, Denmark, ³Nordic Bioscience, Herlev, Denmark
Background/Purpose: Rheumatoid arthritis (RA) is partly characterized by joint destruction. Personalized health care is needed in RA to enable i) prediction of those patients that…
Abstract Number: 367 • 2014 ACR/ARHP Annual Meeting
In Early Rheumatoid Arthritis Patients with Non-Response to Methotrexate Monotherapy the Change in Multi-Biomarker Disease Activity Score Is Differentially Associated with Subsequent Response to Non-Biological Versus Biological Therapy
Karen Hambardzumyan¹, R.J. Bolce², Saedis Saevarsdottir³, Kristina Forslind⁴, Ingemar F. Petersson⁵, Pierre Geborek⁶, Eric H. Sasso², David Chernoff², Scott Cruickshank⁷ and Ronald F. van Vollenhoven⁸, ¹ClinTRID, the Karolinska Institute, Stockholm, Sweden, ²Crescendo Bioscience Inc., South San Francisco, CA, ³Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ⁴Department of Medicine, Karolinska Institute, Stockholm, Sweden, ⁵Lund University, Lund, Sweden, ⁶Section of Rheumatology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden, ⁷Scott Cruickshank and Associates, Inc., Santa Barbara, CA, ⁸Unit for clinical therapy research (ClinTrid), Karolinska Institute, Stockholm, Sweden
Background/Purpose For patients with early RA (eRA), methotrexate (MTX) is recommended as first-line treatment and in non-responders both the addition of conventional non-biological disease modifying…
Abstract Number: 366 • 2014 ACR/ARHP Annual Meeting
Soluble 4-1BB Is a Marker of Joint Involvement and Disease Activity in Rheumatoid Arthritis
Morten Aagaard Nielsen¹, Thomas Andersen², Kristian Stengaard-Pedersen³, Kim Hoerslev-Petersen⁴, Merete Lund Hetland⁵, Peter Junker⁶, Mikkel Ostergaard⁷, Malene Hvid¹ and Bent Deleuran⁸, ¹Department of Biomedicine, Aarhus University, Aarhus, Denmark, ²Dept. of Biomedicine, Aarhus University, Aarhus, Denmark, ³Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ⁴Rheumatology, Research Unit at King Christian X Hospital for Rheumatic Diseases, Graasten, Denmark, ⁵DANBIO, Center for Rheumatology and Spine Diseases, Glostrup University Hospital, Glostrup, Denmark, Glostrup, Denmark, ⁶University of Southern Denmark, Odense, Denmark, ⁷Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, ⁸Dept. of Rheumatology, Aarhus University Hospital, Aarhus, Denmark
Background/Purpose 4-1BB is induced on T cells after antigen encounter and promotes clonal expansion and accumulation of high numbers of antigen-specific effector-type T cells primarily…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].