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  • Abstract Number: 2081 • 2016 ACR/ARHP Annual Meeting

    Dermal Temperature Is an Excelent Prognostic Indicator to Guide RA Therapy

    JoAnn Ball1 and Maria Greenwald2, 1rheumatology, Desert Medical Advances, Palm Deseret, CA, 2Rheumatology, Desert Medical Advances, Palm Desert, CA

    Background/Purpose: Nurses and rheumatology extenders can rapidly identify rheumatoid arthritis (RA) patients who flare, with high predictive value for which individual is at high risk…
  • Abstract Number: 2082 • 2016 ACR/ARHP Annual Meeting

    Identification of Major Clinical Characteristics and Linear Correlations Among DAS28, HAQ and Morning Stiffness Time Using Smart System of Disease Management (SSDM)

    Jianlin Huang1, Hongzhi Wang2, Jing Yang3, Wenqiang Fan4, Hua Wei5, Rong Mu6, Xinwang Duan7, Xiangyuan Liu8, Fang He9, Zhenchun Zhang10, Fei Xiao11, Hui Xiao11, Yuhua Jia11, Yuan Liu11, Li Zhang11, Bing Wu11 and Xiaofeng Li12, 1Department of rheumatology, The Sixth Hospital Affiliated to Sun yat-sen University, Guangzhou, China, 2The First Hospital of Jiaxing, Jiaxing, China, 3Department of rheumatology, Central Hospital of MianYang, Sichuan, Mian Yang, China, 4Department of rheumatology, Central Hospital of XinXiang, Henan, XinXiang, China, 5No 98,Nantong West Rd,Yangzhou, Northern Jiangsu People's Hospital, Yangzhou, China, 6Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, China, 7Department of rheumatology, The Second Affiliated Hospital of Nanchang University, Nanchang, China, 8Department of Rheumatology and Immunology, Peking University Third hospital, Bei jing, China, 9Central Hospital of Sui Ning, Sichuan, Suining, China, 10People's Hospital of Linyi, Shandong, Linyi, China, 11Gothic Internet Technology Corporation, Shanghai, China, 12The Second Affiliated Hospital of Shanxi Medical College, Taiyuan, China

    Background/Purpose: There are more than 5 million rheumatoid arthritis (RA) patients in China, but only 5,000 rheumatologists. Treat-to-target (T2T) is a widely accepted cretria as…
  • Abstract Number: 2083 • 2016 ACR/ARHP Annual Meeting

    Comparing the Electronic Patient Reported Outcome (ePro) Tool Versus the Paper Reported Outcome (pPro) Tool in Rheumatoid Arthritis Patients Treated with Certolizumab Pegol

    Charles Inderjeeth1, Warren Raymond2 and Andrisha Inderjeeth3, 1Rheumatology And Rehab and Aged Care, University of western Australia, North Metro Health Service, Perth WA, Australia, 2Rheumatology and Geriatric Medicine, Sir Charles Gairdner Hospital and University of Western Australia, Nedlands, Australia, 3Sir Charles Gairdner Hospital, Perth, Australia

    Background/Purpose: Clinical disease activity for patients with rheumatoid arthritis requires frequent monitoring for optimal management. Patient reported outcome (PRO) tools provide information that complements physician’s…
  • Abstract Number: 2084 • 2016 ACR/ARHP Annual Meeting

    Effects of a Web-Based Patient Decision Aid on Biologics for Rheumatoid Arthritis: A Proof-of-Concept Study

    Linda Li1, Chris Shaw2, Diane Lacaille1, Elaine Yacyshyn3, C. Allyson Jones4, Paul Adam5, Cheryl Koehn6, Alison Hoens7, Jasmina Geldman8, Charles Goldsmith9, Eric C. Sayre8 and Nick Bansback10, 1Rheumatology, Arthritis Research Canada, Richmond, BC, Canada, 2School of Interactive Arts and Technology, Simon Fraser University, Surrey, BC, Canada, 3University of Alberta, Edmonton, AB, Canada, 4Physical Therapy, University of Alberta, Edmonton, AB, Canada, 5Mary Pack Arthritis Program, Vancouver, BC, Canada, 6Arthritis Consumer Experts, Vancouver, BC, Canada, 7Dept of Physical Therapy, University of British Columbia, Vancouver, BC, Canada, 8Arthritis Research Canada, Richmond, BC, Canada, 9Faculty of Health Sciences, Simon Fraser University, Vancouver, BC, Canada, 10School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada

    Background/Purpose : Under the treat-to-target approach for patients with rheumatoid arthritis (RA), a biologic agent is considered when the target is not met despite trying…
  • Abstract Number: 2085 • 2016 ACR/ARHP Annual Meeting

    Minding the Gap:  the Use of Nurse Practitioners and Physician Assistants in U.S. Rheumatology Practice to Affect Rheumatology Workforce Shortages

    Benjamin J Smith1, Marcy B. Bolster2, Marcia Ditmyer3, Karla B. Jones4, Seetha Monrad5 and Daniel Battafarano6, 1Rheumatology, McIntosh Clinic, P.C., Thomasville, GA, 2Massachusetts General Hospital, Boston, MA, 3University of Nevada, Las Vegas, NV, 4Rheumatology, Nationwide Children's, Columbus, OH, 5Medicine, University of Michigan, Ann Arbor, MI, 6Medicine, San Antonio Military Medical Center, San Antonio, TX

    Title:  Minding the Gap:  The Use of Nurse Practitioners and Physician Assistants in U.S. Rheumatology Practice to Affect Rheumatology Workforce Shortages Authors: Smith BJ1, Bolster…
  • Abstract Number: 2086 • 2016 ACR/ARHP Annual Meeting

    Hexagonal Phase Phospholipid Neutralization Assay Is the Most Sensitive but Least Specific Among Nine Tests for Detecting APS in SLE or Non-SLE Patients

    Katalin Banki1, Phillip Aleksiejuk2, Jessica Patel2 and Andras Perl3, 1Clinical Pathology, SUNY Upstate Medical University, Syracuse, NY, 2Internal Medicine, SUNY Upstate Medical University, Syracuse, NY, 3Department of Medicine, Upstate Medical University, Syracuse, NY

    Background/Purpose: Antiphospholipid antibody syndrome (APS) is an autoimmune, hypercoagulable state which may elicit thrombosis and pregnancy loss.  Although several tests exist to guide diagnosis of…
  • Abstract Number: 2087 • 2016 ACR/ARHP Annual Meeting

    A Type I Interferon Signature in Monocytes and Decreased Levels of Circulating Plasmacytoid Dendritic Cells in Patients with Primary Antiphospholipid Syndrome

    Lucas L. van den Hoogen1, Ruth D.E. Fritsch-Stork2, Marjan A. Versnel3, Ronald H.W.M. Derksen4, Joel A.G. van Roon5,6 and Timothy R.D.J. Radstake5,6, 1Rheumatology and Clinical Immunology, Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 2Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 3Immunology, Erasmus Medical Center, Rotterdam, Netherlands, 4Departments of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 5Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands, 6Department of Rheumatology & Clinical Immunology, UMC Utrecht, Utrecht, Netherlands

    Background/Purpose: In several autoimmune diseases, most notably in systemic lupus erythematosus (SLE), a type I interferon (IFN) signature has been described. This signature is thought…
  • Abstract Number: 2088 • 2016 ACR/ARHP Annual Meeting

    Rituximab Use in Pediatric Lupus Anticoagulant Hypoprothrombinemia Syndrome – Report of Three Cases and Review of the Literature

    Kader Cetin Gedik1, Salma Siddique2, Cassyanne L. Aguiar3 and Doruk Erkan4, 1Pediatric Rheumatology, Cohen Children's Medical Center of New York/ Hofstra Northwell School of Medicine, Lake Success, NY, 2Hospital for Special Surgery- NewYork-Presbyterian / Weill Cornell Medical Center, New York, NY, 3Pediatric Rheumatology, Cohen Children's Medical Center / Hofstra Northwell School of Medicine, Lake Success, NY, 4Rheumatology, Hospital for Special Surgery- Weill Cornell Medicine, New York, NY

    Background/Purpose: Lupus anticoagulant hypoprothrombinemia syndrome (LA-HPS) is a rare condition that may predispose to both thrombosis and bleeding due to positive lupus anticoagulant (LA) and…
  • Abstract Number: 2089 • 2016 ACR/ARHP Annual Meeting

    Deviation of T and B Cell Subset and Its Association with Single Nucleotide Polymorphisms in Patients with Antiphospholipid Syndrome

    Ryo Hisada1, Masaru Kato1, Hisako Nakagawa2, Eri Sugawara1, Masatoshi Kanda1, Kazumasa Ohmura1, Ikuma Nakagawa1, Kenji Oku1, Toshiyuki Bohgaki1, Olga Amengual1, Tetsuya Horita1, Shinsuke Yasuda1 and Tatsuya Atsumi1, 1Division of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan, 2Department of Probiotics Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

    Background/Purpose: Antiphospholipid syndrome (APS) is a well-characterized autoimmune and thrombotic disorder but its pathogenesis remains to be elucidated. Genomic studies have revealed the association of signal…
  • Abstract Number: 2090 • 2016 ACR/ARHP Annual Meeting

    Investigating the Genetic Variations of Antiphospholipid Syndrome By High-Throughput Exome Sequencing

    Sung-Hoon Park1, Chan Uk Lee1, Ji Na Kim2, Ji-Won Kim1, Hwajeong Lee2, Seong-Kyu Kim2 and Jung-Yoon Choe1, 1Medicine, Catholic university of Daegu School of medicine, Daegu, Korea, The Republic of, 2Catholic university of Daegu School of medicine, Daegu, Korea, The Republic of

    Background/Purpose:  The antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence of antiphospholipid antibodies in serum together with clinical manifestations such as thrombosis,…
  • Abstract Number: 2091 • 2016 ACR/ARHP Annual Meeting

    Antiphospholipid Syndrome Patients’ Time within Therapeutic Range of International Normalized Ratio (INR)

    Meghan Greenfield1, Laura Durcan2 and Gregory Del Zoppo2, 1Department of Rheumatology, University of Washington, Seattle, WA, 2University of Washington, Seattle, WA

    Background/Purpose:  Antiphospholipid Syndrome (APS) is a systemic autoimmune disease characterized by recurrent arterial or venous thrombosis and/or recurrent pregnancy morbidities, with persistently positive antiphospholipid antibodies.…
  • Abstract Number: 2092 • 2016 ACR/ARHP Annual Meeting

    Plasma Soluble Triggering Receptor Expressed on Myeloid Cells-1 Is Elevated in Patients with Thrombotic Primary Antiphospholipid Syndrome.  

    Yair Molad1,2, Yonatan Edel3,4, Yael Pri-Paz Basson5, Elisheva Pokroy-Shapira6, Shirly Oren5, Ariela Dortort5 and Vitaly Kliminski4,7, 1Rheumatology Unit, Rheumatology Unit, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel, 2Laboratory of Inflammation Research, Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Petach Tikva, Israel, 3Department of Medicine C, Beilinson Hospital, Rabib Medical Center, Petach Tikva, Israel, 4Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 5Rheumatology Unit, Beilinson Hospital, Rabin Medical Center, Petach Tikva, Israel, 6Rheumatology Unit, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel, 7Laboratory of Inflammation Research, Felsenstein Medical Research Center, Rabin Medical Center, Petach Tikva, Israel

    Background/Purpose : Primary antiphospholipid syndrome (PAPS) is characterized by thrombotic and/or obstetrical morbidity in the presence of persistent antiphospholipid antibodies (APLA) and in the absence…
  • Abstract Number: 2093 • 2016 ACR/ARHP Annual Meeting

    Association of Conventional Risk Factors and Antiphospholipid Antibodies to Thrombosis in Patients with Autoimmune Diseases: Lessons Learned from a Year-Long Systematic Assessment

    Polona Žigon1, Anuška Podovšovnik2, Ales Ambrozic3, Matija Tomsic1, Alojzija Hocevar1, Natasa Gaspersic3, Ziga Rotar1, Sonja Praprotnik4, Snezna Sodin Semrl1,5 and Sašša Čučnik1,6, 1Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, 2Divison of Internal Medicine, General Hospital Izola, Izola, Slovenia, 3Department of Rheumatology, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia, 4Department of Rheumatology, University Medical Centre Ljubljana, Slovenia, Ljubljana, Slovenia, 5Faculty of Mathematics, Natural Science and Information Technology, University of Primorska, Koper, Slovenia, 6Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia

    Background/Purpose: Patients with autoimmune disorders are at risk for thrombotic events and antiphospholipid antibodies (aPL) are one of known markers of increased thrombotic risk. The…
  • Abstract Number: 2094 • 2016 ACR/ARHP Annual Meeting

    Complement Activation in Antiphospholipid Syndrome Due to the Multi-Activated Pathways of the Complement System

    Hiroyuki Nakamura1, Kenji Oku2, Ryo Hisada2, Kazumasa Ohmura2, Masaru Kato2, Toshiyuki Bohgaki2, Olga Amengual2, Tetsuya Horita2, Shinsuke Yasuda2 and Tatsuya Atsumi2, 1Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Japan, 2Division of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan

    Background/Purpose:  Complement activation is proposed as one of the major thrombophilic mechanisms in antiphospholipid syndrome (APS). Among three complement pathways (classical, alternative and lectin), activation…
  • Abstract Number: 2095 • 2016 ACR/ARHP Annual Meeting

    Autoantibodies Against High Density Lipoprotein-Associated Proteins Are Related to Elevated Oxidized Low Density Lipoprotein Levels in Antiphospholipid Syndrome

    Kenji Oku1, Uhei Shibata2, Joana Batuca3, Olga Amengual4, Michihiro Kono2, Hiroyuki Nakamura5, Ryo Hisada1, Kazumasa Ohmura1, Masaru Kato2, Toshiyuki Bohgaki1, Shinsuke Yasuda1, Jose Delgado Alves3,6 and Tatsuya Atsumi1, 1Division of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan, 2Hokkaido University Graduate School of Medicine, Sapporo, Japan, 3CEDOC/NOVA Medical School, Lisbon, Portugal, 4Hokkaido University,Medicine II, Sapporo, Japan, 5Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, Japan, 6Fernando Fonseca Hospital, Amadora, Portugal

    Background/Purpose: Oxidized low-density lipoprotein (oxLDL), a key molecule in atherogenesis, serves as the source of anionic charged particles that bind to beta2glycoprotein I (Β2GPI) and…
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