Abstracts Archive - Page 1272 of 2425 - ACR Meeting Abstracts

Abstract Number: 997 • 2017 ACR/ARHP Annual Meeting
Incidence and Clinical Characteristics of Active Tuberculosis in a Cohort of Patients with Inflammatory Arthritis Treated with TNF-Inhibitors
Ana Maria Gheorghiu¹, Alexandru Garaiman², Alexandra Radu², Alina Soare³, Victoria Arama⁴, Dragos Bumbacea⁵, Rucsandra Dobrota⁶, Raida Oneata⁷, Simona Pintilie², Mihaela Milicescu⁷, Ioan Ancuta⁷, Andrei Martin², Mariana Sasu¹, Claudia Ciofu¹, Liviu Macovei¹, Victor Stoica⁷, Mihai Bojinca⁷ and Carina Mihai⁸, ¹Carol Davila University of Medicine and Pharmacy,Internal Medicine and Rheumatology Department ,,Dr.I.Cantacuzino'' Clinical Hospital, Bucharest, Romania, ²Internal Medicine and Rheumatology, CANTACUZINO HOSPITAL, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, ³Department of Internal Medicine 3 – Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany, ⁴Infectious Diseases 1 Department, Matei Bals National Institute for Infectious Diseases, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, ⁵Department of Pneumology, Elias Emergency University Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, ⁶Department of Rheumatology, Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁷Carol Davila University of Medicine and Pharmacy, Internal Medicine and Rheumatology Department, Cantacuzino Clinical Hospital, Bucharest, Romania, ⁸Internal Medicine and Rheumatology Dept., Cantacuzino Clinical Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Background/Purpose: Tuberculosis (TB) is a major concern in patients receiving TNF inhibitors (TNFi). Objectives: To assess the incidence of active TB and the efficacy of…
Abstract Number: 998 • 2017 ACR/ARHP Annual Meeting
Mental Health in Patients with Axial Spondyloarthritis: Increasing Our Understanding of the Disease. Results from the Spanish Atlas
Marco Garrido-Cumbrera¹, Victoria Navarro-Compán², David Galvez-Ruiz¹, Carlos Jesus Delgado Dominguez¹, Pilar Font-Ugalde³, Olta Brace¹, Pedro Zarco⁴, Jorge Chacon-Garcia¹ and Pedro Plazuelo-Ramos⁵, ¹Universidad de Sevilla, Seville, Spain, ²Rheumatology, Hospital Universitario La Paz, Madrid, Spain, ³Rheumatology service, IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, ⁴H Fundación Alcorcón, Alcorcón, Spain, ⁵CEADE, Madrid, Spain
Background/Purpose: This study’s aim was to assess the association between sociodemographic characteristics, disease progression, and mental health comorbidity with risk of mental disorders (RMD).Methods: In…
Abstract Number: 999 • 2017 ACR/ARHP Annual Meeting
Association between Smoking with Spinal Level of Stiffness and Functional Limitation in Patients with Axial Spondyloarthritis: Results from the Spanish Atlas
Marco Garrido-Cumbrera¹, Victoria Navarro-Compán², Jorge Chacon-Garcia¹, Jordi Gratacos-Masmitja³, David Galvez-Ruiz¹, Eduardo Collantes Estevez⁴, Pedro Zarco⁵ and Olta Brace¹, ¹Universidad de Sevilla, Seville, Spain, ²Rheumatology, Hospital Universitario La Paz, Madrid, Spain, ³Rheumatology, Hospital Parc Taulí, Sabadell - Barcelona, Spain, ⁴Universidad de Cordoba, Cordova, Spain, ⁵H Fundación Alcorcón, Alcorcón, Spain
Background/Purpose: Smoking has been associated with greater disease activity and radiographic progression in patients with Axial Spondyloarthritis (ax-SpA). In addition, radiographic damage has been linked…
Abstract Number: 1000 • 2017 ACR/ARHP Annual Meeting
Use of Mutual Information Theory in Development and Refinement of a Predictive Model for Early Identification of Ankylosing Spondylitis
Atul A. Deodhar¹, Cody Garges², Oodaye Shukla², Theresa Arndt², Tara Grabowsky² and Yujin Park³, ¹Oregon Health & Science University, Portland, OR, ²HVH Precision Analytics, LLC, King of Prussia, PA, ³Novartis Pharmaceuticals Corporation, East Hanover, NJ
Background/Purpose: Delayed diagnosis and treatment of ankylosing spondylitis (AS) contribute to the economic, physical and psychological burden on patients and their caregivers. The objective of…
Abstract Number: 1001 • 2017 ACR/ARHP Annual Meeting
Persistence, Discontinuation, and Switching Patterns Among Ankylosing Spondylitis Patients Newly Initiating Biologic Therapy
Theresa Hunter¹, Krista Schroeder², Sarah Al Sawah² and David Sandoval Calderon², ¹Global Patient Outcomes and Real World Evidence, Eli Lilly and Company, Indianapolis, IN, ²Eli Lilly and Company, Indianapolis, IN
Background/Purpose: The primary goals of treating Ankylosing Spondylitis (AS) patients are to maximize long-term health-related quality of life through control of symptoms and inflammation, prevention…
Abstract Number: 1002 • 2017 ACR/ARHP Annual Meeting
Survival and Years of Potential Life Lost in Connective Tissue Disease and Vasculitis; Data from the Norwegian Connective Tissue Diseases and Vasculitis Registry (NOSVAR)
Torhild Garen¹, Karoline Lerang¹, Anna Maria Hoffmann-Vold², Helena Andersson¹, Øyvind Midtvedt¹, Karin Kilian¹, Ragnar Gunnarsson¹, Birgir Gudbrandsson¹, Gudrun Norby¹, Oyvind Molberg² and Øyvind Palm¹, ¹Department of Rheumatology, Oslo University Hospital, Oslo, Norway, OSLO, Norway, ²Department of Rheumatology, Oslo University Hospital, Oslo, Norway, Oslo, Norway
Background/Purpose: Survival is decreased in patients with connective tissue diseases (CTDs) and vasculitis, however few studies have compared the mortality between the specific diseases prospectively…
Abstract Number: 1003 • 2017 ACR/ARHP Annual Meeting
Hair Treatments and the Risk of Systemic Lupus Erythematosus: the Michigan Lupus Epidemiology & Surveillance (MILES) Program
Emily C. Somers¹, Christina Mrukowicz², Wendy Marder¹, W. Joseph McCune³, Afton L. Hassett⁴, Suzanna Zick⁵, Siobán Harlow⁶ and Caroline Gordon⁷, ¹Internal Medicine-Rheumatology, University of Michigan, Ann Arbor, MI, ²University of Michigan, Ann Arbor, MI, ³Int Med/ Rheum, University of Michigan, Ann Arbor, MI, ⁴Rheumatology, Emory University, Atlanta, GA, ⁵Department of Family Medicine, University of Michigan, Ann Arbor, MI, ⁶Epidemiology Department- School of Public Health, Obstetrics and Gynecology- Medical School, University of Michigan, Ann Arbor, MI, ⁷School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom
Background/Purpose: Hair dye exposure has been reported as a risk factor for systemic lupus erythematosus (SLE) and connective tissue diseases, though conflicting results exist. We…
Abstract Number: 1004 • 2017 ACR/ARHP Annual Meeting
Arthritis Impact at the State and County Level — United States, 2015
Kamil E. Barbour¹, Suson Moss², Janet Croft², Jennifer M. Hootman³, Louise Murphy⁴, Kristina Theis², Yan Wang², Hua Lu², Teresa J. Brady¹ and Charles G. Helmick², ¹Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ²Centers for Disease Control and Prevention, Atlanta, GA, ³Centers for Disease Control and Prevention, Kennesaw, GA, ⁴Division of Population Health, Centers for Disease Control and Prevention, Atlanta, GA
Background/Purpose: Arthritis, a leading cause of disability, affects 54.4 million US adults. By knowing the state and county level arthritis impact, state-level public health professionals…
Abstract Number: 1005 • 2017 ACR/ARHP Annual Meeting
The Prevalence of Patellofemoral Osteoarthritis in China: A Multi-Center Population-Based Cross-Sectional Study
Zhanglai Li¹, Qiang Liu¹, Changsheng Zhao², Yuqing Zhang³, Xiaowei Li¹ and Jianhao Lin¹, ¹Arthritis Clinic and Research Center, Peking University People's Hospital,Peking University, Beijing, China, ²Peking University International Hospital, Peking University International Hospital, Beijing, China, ³School Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: To describe the prevalence and risk factors of patellofemoral osteoarthritis (OA) in a Chinese population.Methods: A multi-center population-based cross-sectional survey was conducted in 2015…
Abstract Number: 1006 • 2017 ACR/ARHP Annual Meeting
Sex Differences in Depressive Symptom Subtypes in Knee Osteoarthritis
Alan Rathbun¹, Megan Schuler², Elizabeth Stuart³, Michelle Shardell⁴, Michelle S. Yau⁵ and Marc Hochberg⁶, ¹Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, ²Rand Coportation, Boston, MA, ³Mental Health, Biostatistics, and Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ⁴Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, ⁵Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, MA, ⁶Department of Medicine, University of Maryland School of Medicine, Baltimore, MD
Background/Purpose: Knee osteoarthritis (OA) is characterized by structural changes in subchondral bone and degradation of articular cartilage, but the pathology does not necessarily lead to…
Abstract Number: 1007 • 2017 ACR/ARHP Annual Meeting
Smoking Signicantly Reduces Effectiveness and Long-Term Survival of Biologic Treatment in Patients with Rheumatoid Arthritis
Roger Rolon Campuzano¹, Andrea Lujan Coronel Ale¹, Osvaldo Luis Cerda¹, Fernando Dal Pra¹, Emilce E Schneeberger¹, María de los Angeles Correa², Marcos Rosemffet¹, Emilio Buschiazzo³, Rodrigo Garcia Salinas⁴, Silvia Papasidero⁵, Belén Barrios⁵, Hernán Maldonado Ficco⁶ and Gustavo Citera⁷, ¹Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, Buenos Aires, Argentina, ²Section Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, Buenos Aires, Argentina, ³Section of Rheumatology, Hospital Señor del Milagro, Salta, Argentina, Salta, Argentina, ⁴Section of Rheumatology, Hospital Italiano de La Plata, Buenos Aires, Argentina, La Plata, Argentina, ⁵Section of Rheumatology, Hospital General de Agudos “Dr. E. Tornú”, Buenos Aires, Argentina, Buenos Aires, Argentina, ⁶section of Rheumatology, Clinica Regional del Sud, Córdoba, Argentina, Córdoba, Argentina, ⁷Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, Buenos Aires, Argentina
Background/Purpose: The introduction of biological agents has been an important advance in the treatment of RA. However, they are not exempt from adverse events and…
Abstract Number: 1008 • 2017 ACR/ARHP Annual Meeting
mtDNA Cybrids from OA Patients Are Less Efficient Using Glycolysis and Are More Susceptible to Apoptosis Under Stress Conditions
Mercedes Fernandez Moreno^1,2, Tamara Hermida-Gómez³, Andrea Dalamao-Fernandez⁴, M. Eugenia Vazquez Mosquera⁴, Estefanía Cortés-Pereira¹, Morena Scotece⁴, Sara Relaño-Fernandez⁵, Ignacio Rego-Pérez¹ and Francisco J Blanco⁶, ¹Servicio de Reumatología. Area Genomica. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, ²CIBER-BBM, Madrid, Spain, ³Rheumatology, INIBIC. Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. CIBER-BBN., A Coruña, Spain, ⁴Servicio de Reumatología. Area Genomica. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A CORUÑA, Spain, ⁵Plataforma de Genómica. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, ⁶Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña. España, A Coruña, Spain
Background/Purpose: Previous studies have showed that chondrocytes from OA patients had mitochondrial alteration in comparison with healthy. However the role of mitochondria in the biological…
Abstract Number: 1009 • 2017 ACR/ARHP Annual Meeting
Novel Non-Coding RNAs Associated with Rheumatoid Arthritis in Asians By Gene-Based Testing
Aleksander Lenert¹ and David W. Fardo², ¹Internal Medicine, Div. of Rheumatology, University of Kentucky, Lexington, KY, ²Biostatistics, College of Public Health, University of Kentucky, Lexington, KY
Background/Purpose: Rheumatoid arthritis (RA) is a complex genetics disease driven by multiple genetic contributors as evidenced by association with over 100 risk SNPs by GWAS.…
Abstract Number: 1010 • 2017 ACR/ARHP Annual Meeting
Identification of Circulating Biomarkers of Disease Activity and Organ Involvement in ANCA-Associated Vasculitis By Targeted Proteomics
Jun Ishizaki¹, Ayako Takemori², Koichiro Suemori¹, Takuya Matsumoto¹, Yoko Akita¹, Masaki Yasukawa¹, Nobuaki Takemori² and Hitoshi Hasegawa¹, ¹Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Ehime, Japan, ²Division of Proteomics Research, Proteo-Science Center, Ehime University, Ehime, Japan
Background/Purpose: Targeted proteomics, which involves quantitative analysis of targeted proteins using selected reaction monitoring (SRM) mass spectrometry, has emerged as a new methodology for discovery…
Abstract Number: 1011 • 2017 ACR/ARHP Annual Meeting
Mitochondrial Haplogroups-Mediated Methylation Regulates Apoptosis in Osteoathritis Cartilage
Ignacio Rego-Pérez¹, Estefanía Cortés-Pereira¹, Juan Fernández-Tajes Sr.², Mercedes Fernandez Moreno¹, Maria Eugenia Vazquez Mosquera¹, Sara Relaño-Fernandez³, Natividad Oreiro⁴, Carlos Fernandez-Lopez¹ and Francisco J Blanco¹, ¹Servicio de Reumatología. Area Genomica. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, ²The Wellcome Trust Center for Human Genetics. McCarthy´s Group. University of Oxford, Oxford, United Kingdom, ³Plataforma de Genómica. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, ⁴1) Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruna, Spain
Background/Purpose: Recent studies revealed that haplogroup J associates with a decreased rate of incident knee Osteoarthritis. Among the functional characteristics of this haplogroup, lower rates…

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