Abstracts Archive - Page 1164 of 2607 - ACR Meeting Abstracts

Abstract Number: 419 • 2019 ACR/ARP Annual Meeting
Real-World Evidence on the Early Effects of Golimumab on Work Productivity and Activity Impairment in Patients with Spondyloarthritis: Interim Results from a Prospective, Observational Study
Panagiotis Athanassiou ¹, Ioannis Kallitsakis ², Gkikas Katsifis ³, Anastasios Kotrotsios ⁴, Georgios Vosvotekas ⁵, Panagiotis Georgiou ⁶, Andreas Bounas ⁷, Yiannis Haratsis ⁸, Evangelia Petrikkou ⁸ and Dimitrios Vassilopoulos⁹, ¹General Hospital of Thessaloniki “Agios Pavlos”, Thessaloniki, Greece, ²Private Practice, Chania, Greece, ³Naval Hospital of Athens, Rheumatology Clinic, Athens, Greece, ⁴Private Practice, Karditsa, Greece, ⁵Euromedica General Clinic of Thessaloniki, Rheumatology Clinic, Thessaloniki, Greece, ⁶General Hospital of Patras “Agios Andreas”, Patras, Greece, ⁷Olympion therapeutirion, Patras, Greece, ⁸Merck Sharp & Dohme Pharmaceutical, Industrial and Commercial S.A, Medical Affairs, Athens, Greece, ⁹2nd Department of Internal Medicine and Laboratory, National and Kapodistrian University of Athens, School of Medicine, Hippokration General Hospital, Athens, Greece
Background/Purpose: There are limited real life data regarding the effect of golimumab on work productivity and activity impairment in rheumatic diseases. The aim of our…
Abstract Number: 420 • 2019 ACR/ARP Annual Meeting
Assessment of Fatigue in Adults with Moderate to Severe Systemic Lupus Erythematosus (SLE): A Qualitative Study to Explore What Patients Feel Should Be Measured in Clinical Trials
Sally Mannix¹, Andrea Beyer ², Vibeke Strand ³, Leslie Hanrahan ⁴, Cristina Abel ⁵, Bruno Flamion ² and Asha Hareendran ⁶, ¹Evidera, Bethesda, ²Idorsia Pharmaceuticals, Allschwil, Switzerland, ³Division of Immunology/Rheumatology, Stanford University, Stanford, CA, ⁴Lupus Foundation of America, Washington DC, ⁵Evidera, Bethesda, MD, ⁶Evidera, London, United Kingdom
Background/Purpose: Fatigue is one of the most common symptoms reported by patients with systemic lupus erythematosus (SLE) and is responsible for considerable loss of time at work…
Abstract Number: 421 • 2019 ACR/ARP Annual Meeting
An Examination of Patient-Reported Outcomes Data from a Randomized Trial Examining Etanercept and Methotrexate as Monotherapy or in Combination in Patients with Psoriatic Arthritis
Vibeke Strand¹, Philip Mease ², Ervant Maksabedian ³, Bradley Stolshek ³, Lyrica Liu ³, David Collier ³, Gregory Kricorian ³ and Joseph Merola ⁴, ¹Division of Immunology/Rheumatology, Stanford University, Stanford, CA, ²Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA, ³Amgen Inc., Thousand Oaks, CA, ⁴Harvard Medical School, Brigham and Women’s Hospital, Boston, MA
Background/Purpose: Health-related quality of life is impacted in patients (pts) with psoriatic arthritis (PsA). Patient-reported outcomes (PROs) are an important means of measuring treatment improvements…
Abstract Number: 422 • 2019 ACR/ARP Annual Meeting
The Impact of Adalimumab vs Placebo on Patient-Reported Outcomes and Utility Measures Among Patients with Moderately to Severely Active Psoriatic Arthritis
Vibeke Strand¹, Pankaj Patel ², Naijun Chen ² and Elizabeth M Lesser ³, ¹Division of Immunology/Rheumatology, Stanford University, Stanford, CA, ²AbbVie Inc., North Chicago, IL, ³AbbVie Inc., North Chicago
Background/Purpose: Physical function and health-related quality of life (HRQoL) are negatively impacted in patients (pts) with PsA, and treatment with conventional and biological (b) DMARDs…
Abstract Number: 423 • 2019 ACR/ARP Annual Meeting
Patient Reported Outcomes over 2 Years in Psoriatic Arthritis Patients Initiating Treatment with 1st, 2nd or 3rd TNF Inhibitor in Routine Care – Was PRO Remission Achieved? Results from the EuroSpA Collaboration
Lykke Midtbøll Ørnbjerg¹, Lennart Jacobsson ², Anne Gitte Loft ³, Florenzo Iannone ⁴, Michael J. Nissen ⁵, Eirik Kristianslund ⁶, Herman Mann ⁷, Maria José Santos ⁸, Manuel Pombo-Suarez ⁹, Kari K. Eklund ¹⁰, Ziga Rotar ¹¹, Bjorn Gudbjornsson ¹², Mehmet Akif Öztürk ¹³, Catalin Codreanu ¹⁴, Marleen van de Sande ¹⁵, Johan Wallman ¹⁶, Ennio Giulio Favalli ¹⁷, Burkhard Moeller ¹⁸, Joe Sexton ¹⁹, Karel Pavelka ⁷, Elsa Vieira-Sousa ²⁰, Carlos Sánchez-Piedra ²¹, Nina Trokovic ²², Matija Tomsic ²³, Thorvardur J Love ²⁴, Ayşe Cefle ²⁵, Ruxandra IONESCU ²⁶, Irene van der Horst-Bruinsma ¹⁵, Gareth Jones ²⁷, Cecilie Heegaard Brahe ²⁸, Merete Lund Hetland ¹ and Mikkel Østergaard ²⁹, ¹DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, ²Dept of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden,, Gothenburg, Sweden, ³Department of Rheumatology, Aarhus University Hospital., Aarhus, Denmark, ⁴Department of Emergency and Transplantation , Rheumatology Unit, University Hospital of Bari, Bari, Italy., Bari, Italy, ⁵University Hospital Geneva, Geneva, Switzerland, ⁶Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway., Oslo, Norway, ⁷Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague 2, Czech Republic, ⁸Rheumatology department, Hospital Garcia de Orta, Almada, Portugal, ⁹Unit Research, Spanish Society of Rheumatology, Madrid, Spain, ¹⁰ROB-FIN registry, Department of Medicine, Helsinki University and University Hospital, Helsinki, Finland, ¹¹UMC LJUBLJANA, DPT. OF RHEUMATOLOGY, LJUBLJANA, Slovenia, ¹²Centre for Rheumatology Research, Landspitali and Faculty of Medicine, University of Iceland, Reykjavik, Iceland, ¹³Division of Rheumatology, Gazi University School of Medicine, Ankara, Turkey, Ankara, Turkey, ¹⁴Center of Rheumatic Diseases, University of Medicine and Pharmacy, Bucharest, Romania., Bucharest, Romania, ¹⁵Amsterdam University Medical Center, Amsterdam, Netherlands, ¹⁶Department of Clinical Sciences Lund, Rheumatology Lund University, Lund, Sweden, ¹⁷University of Milan, Department of Rheumatology, ASST Gaetano Pini-CTO, Milan, Lombardia, Italy, ¹⁸University Hospital Bern, Bern, Switzerland, ¹⁹Diakonhjemmet Hospital, Dept. of Rheumatology, Oslo, Norway, ²⁰Rheumatology and Metabolic Bone Diseases, Hospital de Santa Maria - Centro Hospitalar Lisboa Norte, EPE | Rheumatology Research Unit, Instituto de Medicina Molecular - Faculty of Medicine, University of Lisbon, Lisbon Academic Medical Centre, Lisbon, Portugal,, Lisbon, Portugal, ²¹Research Unit, Spanish Society of Rheumatology, Madrid, Spain, ²²Helsinki University Central Hospital, Helsinki, Finland, ²³Department of Rheumatology, University Medical Centre, Ljubjana, Slovenia, ²⁴Faculty of Medicine, University of Iceland, Reykjavik, Iceland, ²⁵Division of Rheumatology, Kocaeli University School of Medicine, Kocaeli, Turkey, Kocaeli, Turkey, ²⁶SPITALUL CLINIC SFANTA MARIA, Bucharest, ²⁷University of Aberdeen, Aberdeen, United Kingdom, ²⁸Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup, Denmark, Copenhagen, Denmark, ²⁹Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Patient Reported Outcomes (PROs) provide important information on assessment of pain, disease activity, fatigue and physical function in patients with psoriatic arthritis (PsA). Knowledge…
Abstract Number: 424 • 2019 ACR/ARP Annual Meeting
A Novel Patient-Reported Outcome Measure in IgG4-Related Disease: The Symptom Severity Index
Tyler Harkness¹, Karen Donelan ¹, Xiaoqing Fu ¹, Rachel Wallwork ¹, Cory Perugino ¹, John Stone ² and Zachary Wallace ¹, ¹Massachusetts General Hospital, Boston, ²Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA
Background/Purpose: IgG4-related disease (IgG4-RD) causes symptoms, the severity of which vary by organ involvement. The Responder Index (RI) captures physicians’ judgement of disease activity, but…
Abstract Number: 425 • 2019 ACR/ARP Annual Meeting
Differences in Correlation Between Objective Disease Measurements and Patient’s/physician’s Global Assessment in the Large Non-interventional Study SUSTAIN
Jörg Wendler ¹, Peter Wagener ², Schwarze Ilka ³, Evgenia Movshovich⁴, Nils Damann ⁴ and Frank Behrens ⁵, ¹Rheumatologische Schwerpunktpraxis, Erlangen, Germany, ²Fachpraxis für Rheumatologie und Osteologie, Bruchhausen-Vilsen, Germany, ³Praxis für Innere Medizin und Rheumatologie, Leipzig, Germany, ⁴Janssen-Cilag, Neuss, Germany, ⁵Rheumatology Goethe-University Frankfurt & Fraunhofer IME-TMP, Frankfurt, Germany
Background/Purpose: The wish of a treating physician is to make sure, that the patient gets an effective and safe therapy and is satisfied with the…
Abstract Number: 426 • 2019 ACR/ARP Annual Meeting
Time to Response for Clinical and Patient-Reported Outcomes in Patients with Psoriatic Arthritis Treated with Tofacitinib, Adalimumab, or Placebo
Dafna Gladman¹, Laura Coates ², Joseph Wu ³, Lara Fallon ⁴, Ming-Ann Hsu ⁵, Andrew Bushmakin ³, Elizabeth Bacci ⁶, Joseph Cappelleri ³ and Philip Helliwell ⁷, ¹University of Toronto, Toronto, ON, Canada, ²University of Oxford, Oxford, United Kingdom, ³Pfizer Inc, Groton, CT, ⁴Pfizer Inc, Montreal, QC, Canada, ⁵Pfizer Inc, Collegeville, PA, ⁶Evidera, Seattle, WA, ⁷University of Leeds, Leeds, United Kingdom
Background/Purpose: With many disease domains affected in PsA, clinical and patient-reported outcome (PRO) measures are important to assess disease improvement following treatment. Rapid, meaningful improvements…
Abstract Number: 427 • 2019 ACR/ARP Annual Meeting
Correlation Between Patient Reported Outcomes Measurement Information System (PROMIS) and RAPID3 in Rheumatoid Arthritis Patients Starting a New Biologic DMARD
Tyler Williams¹, M. Elaine Husni ², Yuxuan Jin ³, Greg Strnad ¹, Sage O'Bryant ¹ and Chad Deal ⁴, ¹Cleveland Clinic, Cleveland, OH, ²Department of Rheumatologic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, ³Quantitative Health Science, Cleveland Clinic, Cleveland, OH, ⁴Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: RAPID3 is a disease activity measure which relies on patient-reported outcomes (PROs) to assess physical function, pain, and global health but does not require…
Abstract Number: 428 • 2019 ACR/ARP Annual Meeting
Assessing Meaningful Changes in Disease Activity as Clinical Trial Efficacy Measures for Cutaneous Lupus Erythematosus
Srita Chakka¹, Rebecca Krain ¹, Sarah Ahmed ², Josef Concha ¹, Rui Feng ³ and Victoria Werth ⁴, ¹University of Pennsylvania, Philadelphia, PA, ²Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA, Philadelphia, PA, ³University of Pennsylvania, Philadelphia, ⁴Corporal Michael J. Crescenz VAMC, Philadelphia, PA, USA and Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA, Philadelphia, PA
Background/Purpose: To date, there are no approved treatments for cutaneous lupus erythematosus (CLE), a disease known to significantly burden a patient’s quality of life (QoL).…
Abstract Number: 429 • 2019 ACR/ARP Annual Meeting
Concordance Between Physician and Patient Assessment of Disease Activity in Rheumatoid Arthritis Using Disease Activity Score: Phase II Results
Nelly Ziade¹, Samar Alemadi ², Mohammad Abu Jbara ³, Sahar Saad ⁴, Lina El-Kibbi ⁵, Manal Al-Mashaleh ⁶, Bassel El-Zorkany ⁷, Georges Merheb ⁸, Elie Alam ⁹, Alla Aiko ¹⁰, Jamil Messaykeh ¹¹, Nelly Salloum ¹², Amani Daher ¹, Hussein Halabi ¹³, Kamel Mroue' ¹⁴, Basel Masri ¹⁵, Humeira Badsha ¹⁶, Ghita Harifi ¹⁶ and Thurrayya Arayssi ¹⁷, ¹Saint-Joseph University, Beirut, Lebanon, ²Hamad medical corporation, Doha, Qatar, ³Jordan, Amman, Jordan, ⁴King Hamad University Hospital, Bahrain, Bahrain, ⁵Specialized Medical Center, Riyadh, Saudi Arabia, ⁶King Hussein Medical Center, Amman, Jordan, ⁷Cairo University, Cairo, Egypt, ⁸Holy Spirit University of Kaslik, Kaslik, Lebanon, ⁹Levant Hospital, Beirut, Lebanon, ¹⁰Beirut, Beirut, Lebanon, ¹¹Monla Hospital, Tripoli, Lebanon, ¹²RN, Beirut, Lebanon, ¹³King Faisal Specialist Hospital & Research Center, Jeddah, Saudi Arabia, ¹⁴Bahman Hospital, Beirut, Lebanon, ¹⁵Jordan Hospital, Amman, Jordan, ¹⁶Dr Humeira Badsha Medical Center, Dubai, United Arab Emirates, ¹⁷Weill Cornell Medicine-Qatar, Doha, Qatar
Background/Purpose: Involving patients with rheumatoid arthritis (RA) in the assessment of their disease may increase adherence to treatment, improve disease outcomes and reduce consultation time.…
Abstract Number: 430 • 2019 ACR/ARP Annual Meeting
Axial Spondyloarthritis Patients Report Important Impairments in Daily Life and Work Ability – a Web Survey in 472 Patients
Sebastian Ibanez¹, Rianne van Bentum ², Omar Valenzuela ³ and Irene van der Horst-Bruinsma ², ¹Facultad de Medicina Clinica Alemana - UDD, Santiago, Region Metropolitana, Chile, ²Amsterdam University Medical Center, Amsterdam, Netherlands, ³Facultad de Medicina Clinica Alemana -UDD, Santiago, Region Metropolitana, Chile
Background/Purpose: Axial spondyloarthritis (axSpA) can be associated with significant burden and impaired work activity. In Chile, several barriers impede adequate treatment, such as insufficient access…
Abstract Number: 431 • 2019 ACR/ARP Annual Meeting
Psychometric Properties of the Pediatric Patient-Reported Outcomes Measurement Information System (PROMIS®) Item Banks in a Dutch Clinical Sample of Children with Juvenile Idiopathic Arthritis
Michiel Luijten ¹, Caroline Terwee ², Hedy van Oers ², Mala Joosten ³, Merlijn van den Berg ², Dieneke Schonenberg-Meinema ², Koert Dolman ⁴, Rebecca Ten Cate ⁵, Leo Roorda ⁶, Martha Grootenhuis ³, Marion van Rossum⁷ and Lotte Haverman ², ¹Amsterdam University Medical Centers, Amsterdam, Noord-Holland, Netherlands, ²Amsterdam University Medical Centers, Amsterdam, Netherlands, ³Princess Maxima Centre for Pediatric Oncology, Utrecht, Netherlands, ⁴Onze Lieve Vrouwe Gasthuis West, Amsterdam, Netherlands, ⁵Leiden University Medical Centre, Leiden, Netherlands, ⁶Amsterdam Rehabilitation Research Center | Reade, Amsterdam, Netherlands, ⁷Amsterdam University Medical Centers, Amsterdam
Background/Purpose: Patient-reported outcome measures (PROMs) are often used to include the patients perspective on treatment (outcome). However, the choice of PROMs is difficult, as there…
Abstract Number: 432 • 2019 ACR/ARP Annual Meeting
Does Improvement in Patient Pain and Fatigue Lag Behind Clinical Remission in Rheumatoid Arthritis Patients? Data from a Rheumatoid Arthritis Registry
Janet Pope¹, Emmanouil Rampakakis ², Mohammad Movahedi ³, Angela Cesta ⁴, John Sampalis ² and Claire Bombardier ⁴, ¹Western University, London, ON, Canada, ²JSS Medical Research, Montreal, Canada, ³Ontario Best Practices Research Initiative, Toronto General Research Institute University Health Network, Toronto, Canada, ⁴Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada
Background/Purpose: Rheumatoid arthritis (RA) patients are often not in remission due to patient global assessment of disease activity (PtGA) which is included in the formula…
Abstract Number: 433 • 2019 ACR/ARP Annual Meeting
Comparison of PROMIS Computerized Adaptive Testing-Administered Item Banks versus Fixed Short Forms in Juvenile Myositis
Ruchi Patel ¹, Valeria Esparza ², Jin-Shei Lai ¹, Elizabeth Gray ¹, Rowland Chang ³, David Cella ³ and Kaveh Ardalan⁴, ¹Northwestern University Feinberg School of Medicine, Chicago, ²University of Illinois-Chicago College of Medicine, Chicago, ³Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Background/Purpose: Compared to healthy children, youth with juvenile myositis (JM) often report poorer health-related quality of life (HRQoL). Legacy HRQoL measures may underestimate the impact…

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