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Abstract Number: 1043

Ocular Scleral Pathology and Immune-Mediated Inflammatory Diseases. Study of 170 Patients from a Single Universitary Center

Lara Sanchez-Bilbao1, Inigo Gonzalez-Mazon2, José Luis Martín-Varillas3, David Martinez-Lopez4, Carmen Alvarez-Reguera1, Alba Herrero Morant1, Rosalia Demetrio-Pablo1, Vanesa Calvo-Río1, Miguel Ángel González-Gay5 and Ricardo Blanco1, 1Hospital Universitario Marques de Valdecilla, Santander, Spain, 2Hospital Universitario Marques de Valdecilla, Bezana, Spain, 3Hospital Sierrallana, Torrelavega, Spain, 4Hospital Universitario Marques de Valdecilla, Santander (SPAIN), Spain, 5Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain

Meeting: ACR Convergence 2020

Keywords: autoimmune diseases, Eye Disorders, Inflammation

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Session Information

Date: Sunday, November 8, 2020

Session Title: Miscellaneous Rheumatic & Inflammatory Diseases Poster II: Sarcoidosis, Interstitial Lung Disease, & Inflammatory Eye Disease

Session Type: Poster Session C

Session Time: 9:00AM-11:00AM

Background/Purpose: Ocular scleral pathology (OSP) includes episcleritis and scleritis. Episcleritis is generally a benign disease with a self-limited course, while scleritis is a more severe ocular condition. Both may be associated with immune-mediated inflammatory diseases (IMID).

In a wide series with OSP our aim was to assess the a) epidemiological and clinical features and b) relationship with IMID.

Methods: Study of all consecutive patients studied in a single Universitary Hospital during the last ten years with: a) episcleritis and b) scleritis diagnosed by clinical features and slit-lamp (Watson and Hayreh criteria).

Results: We studied 170 patients (101 women/ 69 men) / 340 affected eyes with OSP (episcleritis=132; scleritis=38); mean age at diagnosis 49.03±14.11 years.

OSP was unilateral in 138 (81.2%), recurrent in 70 (41.2%) and chronic in 21 (12.4%). Most of them were idiopathic (n=85, 50%) while associated IMID were 43.5% (TABLE 1).

Topical treatment was used in all patients. In addition to systemic corticosteroids, conventional immunosuppressive and biological drugs were required in 52 cases (30.6%) and 20 (11.8%), respectively (TABLE 2). The main indication for biological therapy was the presence of underlying IMID.

Conclusion: Scleral pathology is a relatively frequent entity and it is necessary to exclude an underlying systemic disease.


Disclosure: L. Sanchez-Bilbao, None; I. Gonzalez-Mazon, None; J. Martín-Varillas, None; D. Martinez-Lopez, Lilly, 2; C. Alvarez-Reguera, None; A. Herrero Morant, None; R. Demetrio-Pablo, None; V. Calvo-Río, None; M. González-Gay, None; R. Blanco, None.

To cite this abstract in AMA style:

Sanchez-Bilbao L, Gonzalez-Mazon I, Martín-Varillas J, Martinez-Lopez D, Alvarez-Reguera C, Herrero Morant A, Demetrio-Pablo R, Calvo-Río V, González-Gay M, Blanco R. Ocular Scleral Pathology and Immune-Mediated Inflammatory Diseases. Study of 170 Patients from a Single Universitary Center [abstract]. Arthritis Rheumatol. 2020; 72 (suppl 10). https://acrabstracts.org/abstract/ocular-scleral-pathology-and-immune-mediated-inflammatory-diseases-study-of-170-patients-from-a-single-universitary-center/. Accessed January 15, 2021.
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