Date: Sunday, October 21, 2018
Session Title: Pain Mechanisms – Basic and Clinical Science Poster – ARHP
Session Type: ACR Poster Session A
Session Time: 9:00AM-11:00AM
Background/Purpose: There are limited studies in the literature indicating that neuropathic pain occurs in knee osteoarthritis (OA) (1). The aim of this cross sectional study was to evaluate frequency of neuropathic pain in knee OA patients and to determine the relation with disease variables.
Methods: Twenty knee OA patients who were not having any comorbid disease and/or using drugs that would cause neuropathy, were recruited to the study. Demographic properties (age, sex, disease duration) and clinical characteristics (functional status by WOMAC and pain intensity by VAS) recorded. The neuropathic property of knee pain was assessed by both LANSS and DN4 scales. Descriptive statistics was used for clinical variables and frequency of neuropathic pain. The difference of clinical variables between patients with and without neuropathic pain, were examined using t tests and chi square tests for continuous and categorical variables respectively. Correlation coefficients of clinical variables and neuropathic pain scores determined by LANSS and DN4, were analyzed with Spearman correlation analyses. The significance threshold was set as p values less than 0.05.
Results: Twenty knee OA patients (11 female, 9male) with a mean age of 55±18 years were included to the study. 11 patients (55%) were defined as having neuropathic pain depending on the LANSS (scores≥12) and DN4 (scores≥4) questionnaire scores. The mean scores of LANSS scale and DN4 were correlated with WOMAC scores
Conclusion: In conclusion neuropathic pain may be common in knee OA patients. Diagnosis and treatment of neuropathic pain are warranted in order to increase functional disability in patients suffering from knee OA.
- Dimitroulas T, Duarte RV, Behura A3, Kitas GD, Raphael Neuropathic pain in osteoarthritis: a review of pathophysiological mechanisms and implications for treatment. Semin Arthritis Rheum. 2014 Oct;44(2):145-54.
To cite this abstract in AMA style:Borman P, Kaygisiz F, Yaman A. Neuropathic Pain in Patients with Knee Osteoarthritis (Preliminary Report) [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10). https://acrabstracts.org/abstract/neuropathic-pain-in-patients-with-knee-osteoarthritis-preliminary-report/. Accessed July 2, 2020.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/neuropathic-pain-in-patients-with-knee-osteoarthritis-preliminary-report/