Session Type: ACR Poster Session C
Session Time: 9:00AM-11:00AM
Neuropathic pain (NP) was accused for increased pain and reduced functional capacity in knee osteoarthritis (KO). Here we aimed to find out the prevalence of neuropathic pain and it’s relationship with gender, age, body mass index (BMI), pain, symptom duration and functional status in patients with KO.
713 patients with KO were included in the study from the multicenter national cohort conducted by the Turkish League Against Rheumatism-Osteoarthritis Study Group. Sociodemographic variables, BMI, and duration of symptoms were recorded. Pain severity was measured by visual analog scale (VAS), neuropathic pain was assessed by PainDETECT questionnaire and Western Ontario and McMaster Universities Arthritis Index (WOMAC) questionnaire and timed up and go test were used for functional evaluation, and somatosensorial dysfunction and characteristics of pain (night pain, relief of pain on rest, pain on motion, aggrevation of symptoms with cold) were also questioned.
The mean age of the patients with KO were 63.29± 9.53 and 83.9 % were female, 16.1% were male, mean duration of symptoms was 80.73±86.59 months (1-720 months), and BMI was 31.5±5.4. NP was found in 20.9 % of the patients and 19.2% of the patients were in the unclear range according to PainDETECT. The age, gender and symptom duration of patients were comparable in patients with or without NP. BMI (31.2±5.4 vs 32.0±5.4, p= 0.016), pain severity (6.35±0.12 vs 6.77±0.29, p=0.004), WOMAC function [31 (3-80) vs 43 (5-106), p=0.036] and WOMAC stiffness [3 (0-16) vs 4 (0-8), p=0.014] scores, night pain (68.4% vs 31.5%, p=0.001) and aggrevation of symptoms by cold (70.4% vs 29.5%, p=0.032) were higher in KO patients with NP. There was no difference between the WOMAC total, WOMAC pain and timed up and go test scores, somatosensorial dysfunction, relief of pain on rest and pain on motion of the patients with or without NP.
BMI and pain severity were higher in KO patients with NP and may probably provoke neuropathic pain which in turn decreases functional capacity. Night pain and aggrevation of symtoms with cold may also be related to neuropathic pain.
To cite this abstract in AMA style:Kaptanoglu E, Şahin O, Tuncer T, Hizmetli S, Altan L, Ayhan F, Bal A, Bilgilisoy M, Bozbas G, Cerrahoglu L, Cevik R, Duruoz T, Dulgeroglu D, Gurer G, Gursoy S, Hepguler S, Kacar C, Kaya T, Melikoglu M, Nas K, Ozcakir S, Ozdolap S, Saridogan M, Sarikaya S, Sindel D, Şendur OF, Tikiz C, Ugurlu H. Neuropathic Pain in Patients with Knee Osteoarthritis and Related Factors: A Multicenter Longitudinal Study-Preliminary Report [abstract]. Arthritis Rheumatol. 2017; 69 (suppl 10). https://acrabstracts.org/abstract/neuropathic-pain-in-patients-with-knee-osteoarthritis-and-related-factors-a-multicenter-longitudinal-study-preliminary-report/. Accessed September 24, 2021.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/neuropathic-pain-in-patients-with-knee-osteoarthritis-and-related-factors-a-multicenter-longitudinal-study-preliminary-report/