Session Title: Osteoarthritis - Clinical Aspects: Imaging and Biomechanics
Session Type: Abstract Submissions (ACR)
Presarcopenia, which is defined as skeletal muscle mass loss, and knee pain have been gained attention with ageing. Little is known about the association of lower extremity presarcopenia (LEPS) and severity of knee pain. Thus, this study was conducted to the relationship between severity of self-reported knee pain and LEPS.
From the 5th Korean National Health and Nutrition Examination Survey (KNHNES V1-2, n=17,476), the data of 721 participants, who underwent dual x-ray absorptiometry (DXA) and bilateral knee plain radiographs, and complained knee pain were analyzed. LEPS was defined as a lower extremity skeletal muscle mass index below -2SD of the value in sex-matched young reference groups. Participant were categorized into 4 groups; normal, LEPS, non-LEPS with obesity (NLEPSO), LEPS with obesity (LEPSO).
LEPS and LEPSO are significantly associated with the severity of knee pain (LEPS 6.9±0.4, LEPSO 7.2±0.5, P<0.05). These results did not change after adjusting for various confounding factors. In participants with non-radiographic knee OA (n=268), the severity of knee pain was related with LEPS (7.2±0.6, P<0.05). In radiographic knee OA participants (n=452), LEPSO was related with severity of knee pain (7.3±0.5, P<0.05). Sex, smoking status, osteoporosis, and vitamin D levels were not related with the severity of self-reported knee pain.
LEPS is directly associated with severity of knee pain. This attribution supports increasing muscle mass is very important to reduce knee pain. Thus, early detection of LEPS may help physicians to detect pain-sensitive LEPS patients who can benefit from early intervention such as exercise.
Y. H. Cheon,
W. H. Yoo,
Y. S. Suh,
H. O. Kim,
K. S. Park,
S. I. Lee,
H. J. Jeon,
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