ACR Meeting Abstracts

ACR Meeting Abstracts

  • Home
  • Meetings Archive
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018 ACR/ARHP Annual Meeting
    • 2017-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • Meeting Resource Center

Abstract Number: 1549

Experience from a Diverse Rheumatology Cohort with COVID-19: Are We Doing Better Than We Expected?

Michael Grant1, Matas Orentas2, Sobia Hassan1, Sonali Khandelwal1, Donyea Moore3 and Najia Shakoor1, 1Rush University, Chicago, IL, 2RUMC, Chicago, IL, 3Rush University Medical Center, Chicago, IL

Meeting: ACR Convergence 2021

Keywords: Anti-TNF Drugs, COVID-19, Disease-Modifying Antirheumatic Drugs (Dmards), Miscellaneous Rheumatic and Inflammatory Diseases, Outcome measures

  • Tweet
  • Email
  • Print
Session Information

Date: Tuesday, November 9, 2021

Session Title: Infection-related Rheumatic Disease Poster (1530–1564)

Session Type: Poster Session D

Session Time: 8:30AM-10:30AM

Background/Purpose: The COVID-19 pandemic has been particularly concerning for patients with rheumatologic conditions because they are potentially predisposed to more severe outcomes. Studies have suggested that higher steroid dose, rituximab and certain DMARDs were associated with worse COVID-19 outcomes while TNF-inhibitors were associated with better outcomes. However, more studies are needed to confirm these trends particularly in more diverse patient populations. Here, we evaluate a predominantly Black and Hispanic cohort of rheumatology patients with COVID-19 compared to controls on their infection-related outcomes.

Methods: An urban academic medical center has a registry of patients with rheumatological conditions and laboratory confirmed COVID-19 as well as a separate repository of COVID-19 patients without rheumatic disease. Data collected included demographics, comorbidities, medications, hospitalization and hospital course. Chi-squared, independent samples t-test, and logistic regression were used for analyses.

Results: Results are summarized in Tables 1 and 2. 175 rheumatology patients (43 SLE, 52 RA, 26 psoriasis and psoriatic arthritis, 22 other connective tissue diseases, 32 other diagnoses including inflammatory arthritis and myositis) and 481 control patients were evaluated. Both groups had a substantial portion of Black patients while the rheumatology group also included a significant number of Hispanic patients. Prevalence of DM was higher in the control group.

Patients with rheumatic disease had longer length of stay in the hospital (p=0.034), however, overall did not have increased odds of hospitalization, ICU admission, intubation, or death even after adjustment for confounders. GC and DMARD use were not associated with overall outcomes. There was decreased odds of hospitalization with use of TNF-inhibitors. Rituxan use was associated with increased odds of hospitalization and death.

Conclusion: This predominantly Black and Hispanic cohort of rheumatology patients with COVID-19 had very comparable outcomes overall to those without rhematic disease. TNF-inhibitor use was associated with decreased risk of hospitalization while rituximab use was associated with increased risk of hospitalization and death. These results are reassuring for our patients overall but suggest that we need to continue to evaluate subsets of our patients on specific therapies for potentially better or worse outcomes. Continued sharing of data across the country and world will be invaluable in helping us provide appropriate guidance and management for our patients.


Disclosures: M. Grant, None; M. Orentas, None; S. Hassan, None; S. Khandelwal, None; D. Moore, None; N. Shakoor, DJO/DR. Comfort, 9, 10.

To cite this abstract in AMA style:

Grant M, Orentas M, Hassan S, Khandelwal S, Moore D, Shakoor N. Experience from a Diverse Rheumatology Cohort with COVID-19: Are We Doing Better Than We Expected? [abstract]. Arthritis Rheumatol. 2021; 73 (suppl 9). https://acrabstracts.org/abstract/experience-from-a-diverse-rheumatology-cohort-with-covid-19-are-we-doing-better-than-we-expected/. Accessed February 3, 2023.
  • Tweet
  • Email
  • Print

« Back to ACR Convergence 2021

ACR Meeting Abstracts - https://acrabstracts.org/abstract/experience-from-a-diverse-rheumatology-cohort-with-covid-19-are-we-doing-better-than-we-expected/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

ACR Pediatric Rheumatology Symposium 2020

© COPYRIGHT 2023 AMERICAN COLLEGE OF RHEUMATOLOGY

Wiley

  • Home
  • Meetings Archive
  • Advanced Search
  • Meeting Resource Center
  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences