ACR Meeting Abstracts

ACR Meeting Abstracts

Abstract Number: 587

Clinical Characteristics of Nonradiographic Axial Spondyloarthritis in Korea: A Comparison with Ankylosing Spondylitis

Hyungjin Kim1, Hyemin Jeong1, Seulkee Lee1, Inyoung Kim1, Jiwon Hwang2, Jaejoon Lee1, Jinseok Kim3, Eun-Mi Koh4 and Hoon-Suk Cha5, 1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 2Department of Medicine,Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 31753-3, Ara-1 Dong, Jeju National University Hospital, Jeju, South Korea, 4Dept of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 5Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea

Meeting: 2014 ACR/ARHP Annual Meeting

Keywords: , ,

Session Information

Title: Spondyloarthropathies and Psoriatic Arthritis - Clinical Aspects and Treatment I

Session Type: Abstract Submissions (ACR)

Background/Purpose: To evaluate the clinical characteristics and outcomes of nonradiographic axial spondyloarthritis (nr-axSpA) in Korean patients.

Methods: A retrospective analysis evaluated 155 patients with nr-axSpA at a single tertiary hospital between January 2001 and January 2011. Baseline characteristics and clinical courses were reviewed and compared with those of patients with ankylosing spondylitis (AS).  

Results: The mean age at disease onset was 29.5 ± 10.8 years, and 52 (33.5%) patients were female. The mean age at symptom onset was older (29.5 ± 10.8 vs. 25.9 ± 9.2, respectively, p < 0.001) and the male to female ratio was lower (2:1 vs. 5:1, respectively, p = 0.001) in patients with nr-axSpA compared with patients with AS. The proportion of females was higher among patients with late onset-SpA than early-onset nr-axSpA (55.0 vs. 30.1%, respectively, p = 0.029). Among 74 patients with nr-axSpA, whose follow-up duration was more than 1.5 years, 29 (39.2%) patients progressed to AS during the follow-up period. The proportion of females was lower in progressors that that of non-progressors (13.8 vs. 44.4%, respectively, p = 0.010). Presence of syndesmophyte and minimal X-ray changes at baseline were frequently observed in progressors compared with non-progressors (26.7 vs. 0.0 %, p = 0.006 and 69.0 vs. 35.6%, p = 0.005, respectively).

Conclusion: The predominance of male patients is more prominent among Korean patients with SpA compared with Caucasians. Female nr-axSpA patients had late symptom onset and less progression to AS. X-ray changes at baseline were associated with radiographic progression.

Disclosure:

H. Kim,
None;

H. Jeong,
None;

S. Lee,
None;

I. Kim,
None;

J. Hwang,
None;

J. Lee,
None;

J. Kim,
None;

E. M. Koh,
None;

H. S. Cha,
None.

« Back to 2014 ACR/ARHP Annual Meeting

ACR Meeting Abstracts - https://acrabstracts.org/abstract/clinical-characteristics-of-nonradiographic-axial-spondyloarthritis-in-korea-a-comparison-with-ankylosing-spondylitis/