A Comparative Study of Serositis Between Inpatients with Psoriatic Arthritis and Rheumatoid Arthritis

Ashmia Saif¹, Priyanka Dongare², Meghan Beard³, Yunhan Liao⁴, Xiaoyue Zhang⁴, Qingping Yao⁵ and Asha Patnaik⁶, ¹Stony Brook University Hospital, Syosset, NY, ²Stony Brook University Hospital, Highland, NY, ³Stony Brook Southampton, Moriches, NY, ⁴Biostatistical Consulting Core - Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, ⁵Stony Brook University, Stony Brook, NY, ⁶Stony Brook University Medical Center, East Setauket, NY

Meeting: ACR Convergence 2023

Keywords: autoimmune diseases, Cohort Study, Psoriatic arthritis, rheumatoid arthritis

Session Information

Date: Sunday, November 12, 2023

Title: (0483–0509) Spondyloarthritis Including Psoriatic Arthritis – Diagnosis, Manifestations, & Outcomes Poster I: PsA

Session Type: Poster Session A

Session Time: 9:00AM-11:00AM

Background/Purpose: Autoimmune diseases such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA) can causes erositis including pericarditis and pleuritis. However, the rate of serositis in PsA is not defined, though several case reports have described pleuropericardial involvement. The prevalence of pericarditis in RA ranges from 30% to50%. This study aimed to estimate the frequency of pleuropericarditis in PsA vs RA.

Methods: A retrospective chart review of hospitalized patients with RA and PsA was conducted between 2013 and 2021. The frequencyof pericarditis or pleuritis was compared between RA and PsA patients. This study was approved by the Institutional Review Board of Stony Brook University.

Results: There were a total of 113 inpatients aged 18 and 65 (Table 1). These patients were divided into two groups: 57 patients with RA (Group 1) and 56 with PsA (Group 2). Of the 57 RA patients, 48 patients had pericardial or pleural effusions and 46 were determined to have idiopathic etiology. Of the 56 PsA patients, 42 had pericardial or pleural effusions and 23 were considered idiopathic. Approximately 41% of PsA patients had idiopathic pericardial or pleural effusions as compared with 81% RA patients. This shows a statistically significant difference between the two groups (P < 0.0001).

Conclusion: This study suggests that both RA and PsA patients can cause pleuropericarditis, and the frequency of idiopathic etiology in RA may be two-fold higher than PsA. Further study using a larger cohort of patients is warranted to accurately estimate the rate of serositis.

References
1. Movahedian M, et al. Chest pain due to pericardial effusion as initial presenting feature of rheumatoid arthritis: case report and review of the literature. Cardiology research. 2017; 8(4): 161.
2. Esposito M, et al. Resolution of idiopathic recurrent pericarditis in a psoriatic arthritis patient treated with etanercept. European Journal of Dermatology. 2012; 22(1): 151-152.

Table 1: comparison of pleuropericardial involvement between psoriatic arthritis and rheumatoid
arthritis

Disclosures: A. Saif: None; P. Dongare: None; M. Beard: None; Y. Liao: None; X. Zhang: None; Q. Yao: None; A. Patnaik: None.

To cite this abstract in AMA style:

Saif A, Dongare P, Beard M, Liao Y, Zhang X, Yao Q, Patnaik A. A Comparative Study of Serositis Between Inpatients with Psoriatic Arthritis and Rheumatoid Arthritis [abstract]. Arthritis Rheumatol. 2023; 75 (suppl 9). https://acrabstracts.org/abstract/a-comparative-study-of-serositis-between-inpatients-with-psoriatic-arthritis-and-rheumatoid-arthritis/. Accessed .

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