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Abstracts tagged "Cohort Study"

  • Abstract Number: L01 • ACR Convergence 2020

    Outcomes of COVID-19 Infection in Patients with Rheumatic Diseases in a Multicenter Healthcare System: A Comparative Cohort Study

    Naomi Serling-Boyd1, Kristin D'Silva1, Tiffany Hsu2, Xiaoqing Fu3, Rachel Wallwork4, April Jorge1, Yuqing Zhang1, Ellen Gravallese5, Hyon K. Choi6, Jeffrey Sparks7 and Zachary Wallace8, 1Massachusetts General Hospital, Boston, MA, 2Brigham and Women's Hospital, Jamaica Plain, MA, 3Mass General Hospital, Boston, MA, 4Johns Hopkins Hospital, Baltimore, MA, 5Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 6MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA, 7Brigham and Women's Hospital, Boston, MA, 8Massachusetts General Hospital, Newton, MA

    Background/Purpose: The risk of poor outcomes from COVID-19 among rheumatic disease patients compared to the general population remains poorly understood. Filling this knowledge gap is…
  • Abstract Number: 0022 • ACR Convergence 2020

    Association Between Changes in Pain Sensitization and Changes in Disease Activity After 12 Weeks of Disease Modifying Anti-Rheumatic Drug Therapy in Rheumatoid Arthritis

    Andrew Heisler1, Jing Song2, Lutfiyya Muhammad3, Alyssa Wohlfahrt4, Wendy Marder5, Marcy Bolster6, Clifton Bingham III7, Daniel Clauw8, Dorothy Dunlop9, Tuhina Neogi10 and Yvonne Lee3, 1Northwestern University Feinberg School of Medicine, Oak Park, IL, 2Northwestern University, Chicago, 3Northwestern University Feinberg School of Medicine, Chicago, IL, 4Brigham and Womans Hospital, Boston, MA, 5University of Michigan, Ann Arbor, MI, 6Massachusetts General Hospital, Concord, MA, 7Johns Hopkins University, Baltimore, MD, 8Michigan Medicine, Ann Arbor, MI, 9Northwestern University, New Haven, CT, 10Boston University School of Medicine, Boston, MA

    Background/Purpose: Patients with rheumatoid arthritis (RA) have abnormalities in central nervous system regulation of pain, leading to enhanced pain sensitivity at joint sites (peripheral sensitization)…
  • Abstract Number: 0576 • ACR Convergence 2020

    Medical Savings of Timely Rheumatoid Arthritis Diagnoses

    Kathryn Johnson1, Christine Sawicki1, Cristina Sotelo2, Tanvi Kalevar3, Sylvie Lardeux4, Fabio Casadio3, David Baghdadi5, Michele Hamburger6, Elisea Avalos-Reyes7 and Kjel Johnson1, 1CVS Health, Lincoln, RI, 2CVS Health, Austin, TX, 3CVS Health, New York, NY, 4CVS Health, Wellesley, MA, 5CVS Health, Woonsocket, RI, 6Frances Hamburger Institute, Hauppauge, NY, 7CVS Health, Irving, TX

    Background/Purpose: Previous studies suggest that early rheumatoid arthritis (RA) recognition and treatment provides greater clinical benefits than treatment started later in the disease course. However,…
  • Abstract Number: 1015 • ACR Convergence 2020

    The Prevalence and Risk Factors for Liver Fibrosis Among Rheumatoid Arthritis (RA) Patients on Disease-Modifying Anti-rheumatic Drugs (DMARDs)

    Chou Luan Tan1, Boon Han Ng2, Noor Shahrazat Ahmad2, Shahrul Aiman Soelar2, Muhammad Zulhilmi Asyraf Jazlan2, Mohd Ammar Dzakirin Md Mansor2, Mohd Azri Mohd Suan2, Kuang Kiat Kiew2, Zalwani Zainuddin2, Muhammad Radzi Abu Hassan2 and Chong Hong Lim2, 1Hospital Sultanah Bahiyah, Kementerian Kesihatan Malaysia, Alor Setar, Kedah, Malaysia, 2Hospital Sultanah Bahiyah, Alor Setar, Kedah, Malaysia

    Background/Purpose: Majority of DMARDs, including methotrexate (MTX), leflunomide (LEF) and sulfasalazine (SSZ) arebelieved to be hepatotoxic, causing liver fibrosis. However, the clinical findings were inconsistent.…
  • Abstract Number: 1343 • ACR Convergence 2020

    Early Real-World Experience of Tofacitinib for Psoriatic Arthritis: Data from a United States Healthcare Claims Database

    Philip Mease1, Pamela Young2, David Gruben3, Lara Fallon4, Rebecca Germino5 and Arthur Kavanaugh6, 1Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, 2Pfizer Inc, Collegeville, PA, 3Pfizer Inc, Groton, CT, 4Pfizer Inc, Montreal, QC, Canada, 5Pfizer Inc, New York, NY, 6UC San Diego Health System, San Diego, CA

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of psoriatic arthritis (PsA). It was approved in the US in December 2017 for…
  • Abstract Number: 1874 • ACR Convergence 2020

    Differences Between Men and Women in the Patient Pathways to Diagnosis of Ankylosing Spondylitis

    Mark Hwang1, Martin Rozycki2, Theresa Arndt2, Esther Yi3 and Michael Weisman4, 1McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, 2HVH Precision Analytics, LLC, Wayne, PA, 3Novartis Pharmaceuticals Corporation, East Hanover, NJ, 4Cedars Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA

    Background/Purpose: Healthcare claims databases can be used to identify patients with ankylosing spondylitis (AS) prior to diagnosis. This study explores differences in pathways to AS…
  • Abstract Number: 0089 • ACR Convergence 2020

    The Risk Factors of Recurrence in Relapsing Polychondritis; A Study of 41 Cases

    Tsuneyasu Yoshida1, Hajime Yoshifuji2, Mirei Shirakashi1, Koji Kitagori1, Shuji Akizuki2, Ran Nakashima1, Kosaku Murakami1, Motomu Hashimoto3, Masao Tanaka3 and Koichiro Ohmura1, 1Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, Kyoto, Kyoto, Japan, 2Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, Kyoto, Japan, 3Department of Advanced Medicine for Rheumatic Diseases, Kyoto University Graduate School of Medicine, Kyoto, Kyoto, Japan

    Background/Purpose: Relapsing polychondritis (RP) is a rare disease which causes inflammation in systemic cartilages. Although glucocorticoids (GC) and immunosuppressive drugs (IS) have been used, the…
  • Abstract Number: 0584 • ACR Convergence 2020

    Total Cost of Care for Patients with Rheumatoid Arthritis

    Kjel Johnson1, Rebecca Karos2, Elisea Avalos-Reyes3, Fabio Casadio4, Michele Hamburger5 and Chiara Leprai4, 1CVS Health, Lincoln, RI, 2CVS Health, Wellesley, MA, 3CVS Health, Irving, TX, 4CVS Health, New York, NY, 5Frances Hamburger Institute, Hauppauge, NY

    Background/Purpose: The range of medical costs associated with rheumatoid arthritis (RA) is, in part, related to the various treatment options. Treatment for RA focuses on…
  • Abstract Number: 1037 • ACR Convergence 2020

    Relationship Between Air Quality and Sarcoidosis Inflammatory Activity

    Aaron Case1, Dustin Fraidenburg2, Israel Rubinstein2 and Christian Ascoli2, 1University of Illinois at Chicago, Chicago, IL, 2Division of Pulmonary,Critical Care, Sleep and Allergy; Department of Medicine, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA, Chicago, IL

    Background/Purpose: African Americans [AA] and minorities in the lower socioeconomic strata of Chicago are disproportionately affected by pulmonary sarcoidosis, and regularly exposed to poorer air…
  • Abstract Number: 1464 • ACR Convergence 2020

    Multi-Variate Approach Including Serology and Genetics for an Improved Identification of Patients at Risk of Developing Rheumatoid Arthritis

    Céline Lamacchia1, Maresa Grundhuber2, Isabel Gehring2, Pascale Roux Lombard3, Michael John Nissen1, Andrea Rubbert Roth4, Ruediger Mueller5, Ulrich Walker6, Burkhard Moeller7, Diego Kyburz8, Adrian Ciurea9, Sascha Swiniarski10 and Axel Finckh11, 1Geneva University Hospital, Geneva - 14, Switzerland, 2Thermo Fisher Scientific Phadia GmbH, Freiburg, Germany, 3Geneva University Hospital, Geneva, Switzerland, 4Klinik für Rheumatologie, Kantonsspital St Gallen, St Gallen, Sankt Gallen, Switzerland, 5KSA: Aarau Hospital, Aarau, Switzerland, 6Basel University Hospital, Basel, Switzerland, 7Inselspital - University Hospital Bern, Bern, Switzerland, 8University Hospital Basel, Basel, Switzerland, 9University Hospital Zurich, Zurich, Switzerland, 10Phadia GmbH / Thermo Fisher Scientific, Freiburg, Germany, 11Division of Rheumatology, University Hospitals of Geneva, Geneva, Switzerland

    Background/Purpose: First-degree relatives of RA patients (FDR-RA) have an increased prevalence for rheumatoid arthritis (RA) [1] and joint symptoms [2]. Identification of individuals with imminent RA…
  • Abstract Number: 1892 • ACR Convergence 2020

    Pattern and Influential Factors in Promoting Treat-to-Target (T2T) for F Ankylosing Spondylitis (AS) Patients with the App of Smart System of Disease Management (SSDM): A Cohort Study from China

    Jing Xue1, Hongzhi Wang2, Hongbin Li3, Hui Song4, Yasong Li5, Xiaofei Shi6, Hongjun Zhao7, Feng Wei8, Bing Wu9, Hui Xiao10, Yuhua Jia9, Fei Xiao9 and Huaxiang Wu1, 1The Second Affiliated Hospital of Zhejiang University school of Medicine, Hangzhou, China (People's Republic), 2The First Hospital of Jiaxing, Jiaxing, China (People's Republic), 3The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China (People's Republic), 4Beijing Jishuitan Hospital, Beijing, China (People's Republic), 5Zhejiang Provincial People's Hospital, Hangzhou, China (People's Republic), 6The First Affiliated Hospital of Henan University of science and technology, Luoyang, China (People's Republic), 7Xiangya Hospital of Central South University, Changsha, China (People's Republic), 8Jiangmen Central Hospital Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen, China (People's Republic), 9Shanghai Gothic Internet Technology Co., Ltd., Shanghai, China (People's Republic), 10Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic)

    Background/Purpose: Ankylosing Spondylitis Disease Activity Score (ASDAS) is adopted to evaluate the degree of disease activity and the inflammatory response in AS patients. ASDAS score…
  • Abstract Number: 0178 • ACR Convergence 2020

    Associations of Multimorbidity with DMARD Initiation and Achieving Target Disease Activity Thresholds in Active Rheumatoid Arthritis: A Cohort Study Using the Rheumatology Informatics System for Effectiveness (RISE) Registry

    Bryant England1, Huifeng Yun2, Lang Chen3, Kaleb Michaud1, Ted Mikuls1 and Jeffrey R Curtis2, 1University of Nebraska Medical Center, Omaha, NE, 2Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 3University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Although a treat-to-target strategy is endorsed in rheumatoid arthritis (RA) treatment guidelines, its routine implementation in real-world settings, particularly in the context of multimorbidity,…
  • Abstract Number: 0623 • ACR Convergence 2020

    Cytokine Storm: Outcomes in SARS-CoV-2 Patients Treated with Biologics in a Rheumatology Cohort

    Neha Chiruvolu1, Muntarin Karim2, Patil Injean3, Sandy Lee3, Karina Torralba4, Christina Downey3, Mehrnaz Hojjati5, Loomee Doo5, Donna Jose6, Deepa Panikkath3, Micah Yu5, Anna Lafian5, Marven Cabling5 and Vaneet Sandhu7, 1UC Riverside School of Medicine, Riverside, CA, 2Loma Linda University Health System, Loma Linda, CA, 3Loma Linda University Medical Center, Redlands, CA, 4Loma Linda University School of Medicine, Redlands, CA, 5Loma Linda University Medical Center, Loma Linda, CA, 6Loma Linda University Medical Center, Ontario, CA, 7Loma Linda University, Loma Linda, CA

    Background/Purpose: Cytokine Release Syndrome (CRS) or Macrophage Activation Syndrome (MAS) is a life threating hyperinflammatory condition that can complicate rheumatic disease as well as infections…
  • Abstract Number: 1082 • ACR Convergence 2020

    The Presence of Anti-Jo1, anti-PL7, And/or anti-MDA5 Antibodies in Idiopathic Inflammatory Myopathy Confers an Increased Risk of a Significant Restrictive Pulmonary Defect

    Dmitriy Cherny1 and Carrie Richardson1, 1Rush University Medical Center, Chicago, IL

    Background/Purpose: A subset of patients with idiopathic inflammatory myopathy develop significant restrictive lung disease, although risk factors for this are poorly defined. Autoantibodies may be…
  • Abstract Number: 1492 • ACR Convergence 2020

    The Childhood Arthritis and Rheumatology Research Alliance Start Time Optimization of Biologic Therapy in Polyarticular JIA Study: Report of Primary Study Outcomes

    Yukiko Kimura1, George Tomlinson2, Laura Schanberg3, Mary Ellen Riordan4, Anne Dennos5, Vincent Del Gaizo6, Katherine Murphy7, Pamela F. Weiss8, Brian Feldman9 and Sarah Ringold10, 1Hackensack Meridian School of Medicine, Hackensack, NJ, 2Department of Medicine, University Hospital Network, Toronto, Toronto, ON, Canada, 3Duke University Medical Center, Durham, NC, 4Hackensack University Medical Center, Westwood, NJ, 5Duke University, Durham, NC, 6Childhood Arthritis & Rheumatology Research Alliance (CARRA), Whitehouse Station, NJ, 7Lousiana Department of Public Health, New Orleans, LA, 8Children's Hospital of Philadelphia, Philadelphia, 9The Hospital for Sick Children, Toronto, ON, Canada, 10Seattle Children's, Seattle, WA

    Background/Purpose: There is uncertainty regarding when to start biologic medications for polyarticular juvenile idiopathic arthritis (P-JIA). The Childhood Arthritis and Rheumatology Research Alliance (CARRA) developed…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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