Abstract Number: 605 • 2012 ACR/ARHP Annual Meeting
Increased Incidence of Herpes Zoster Among Patients with Systemic Lupus Erythematosus
Background/Purpose: Herpes zoster (HZ) is the painful reactivation of latent varicella zoster virus infection. The incidence of HZ may be increased in some autoimmune…Abstract Number: 2257 • 2012 ACR/ARHP Annual Meeting
Association of Low Vitamin D with High Disease Activity in an Australian Systemic Lupus Erythematosus Cohort
Background/Purpose: Previous cross-sectional studies suggest that low vitamin D may be associated with higher disease activity in SLE. Vitamin D status varies with geographic location…Abstract Number: 940 • 2012 ACR/ARHP Annual Meeting
Incidence of Systemic Lupus Erythematosus in England, 1998-2010
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic auto-immune disease associated with a wide spectrum of clinical manifestations and increased mortality. The most recent data…Abstract Number: 2683 • 2012 ACR/ARHP Annual Meeting
Interferon-Associated Cytokine and Chemokine Expression in Patients with Serologically Active Clinically Quiescent (SACQ) Systemic Lupus Erythematosus (SLE)
Background/Purpose: Interferon-α (IFN-α) plays a prominent pro-inflammatory role in SLE. Studies suggest clinical/serologic discordance may illuminate SLE pathophysiology: peripheral IFN-α production is blunted in autoantibody-producing,…Abstract Number: 2260 • 2012 ACR/ARHP Annual Meeting
Serum DNAse I Anti DNAse I Antibodies , CRP and Antibodies to CRP Relation to Disease Activity in Systemic Lupus Eryhtematous: Longitudinal Studies
Background/Purpose: Defective clearance of both nuclesomes and immune complexes has been suggested to intiate and perpetuate the disease. Defects in DNAse I gene in mice have shown SLE like symptoms,…Abstract Number: 942 • 2012 ACR/ARHP Annual Meeting
Validity and Reliability of the Lupus Damage Index Questionnaire (LDIQ): A Prospective Study
Background/Purpose: The Systemic Lupus International Collaborating Clinics/American College of Rheumatology (ACR) Damage Index (SDI) is a validated instrument for assessing organ damage in systemic lupus…Abstract Number: 1897 • 2012 ACR/ARHP Annual Meeting
Pregnancy and Contraception in Adolescents and Teens with SLE: Are pediatric rheumatologists adequately Screening and Educating Their Patients?
Background/Purpose: Pregnancy in patients with systemic lupus erythematosus (SLE) is often complicated by both disease flares and risks to the fetus. It is important that young women with SLE be educated on both the…Abstract Number: 943 • 2012 ACR/ARHP Annual Meeting
Impact of Systemic Lupus Erythematosus On Work Productivity and Income in the United States
Background/Purpose: Systemic lupus erythematosus (SLE) is a complex, chronic autoimmune disorder characterized by fluctuating periods of disease activity affecting multiple organ systems. This study was…Abstract Number: 1795 • 2012 ACR/ARHP Annual Meeting
Correction for Basophil and Monocyte Frequencies Identifies Specific Gene Expression Differences Associated with SLE Disease Flare: Interim Report From the Bold (Biomarkers of Lupus Disease) Study
Background/Purpose: Heterogeneity of clinical manifestations and pathogenic mechanisms has complicated treatment of SLE patients. The BOLD study allows evaluation of gene expression changes associated with…Abstract Number: 944 • 2012 ACR/ARHP Annual Meeting
Job-Related Burden and Effort-Reward Imbalance in Patients with Systemic Lupus Erythematosus
Background/Purpose: Working life factors influence patients’ (life) satisfaction and well being. Effort at work is part of a social contract that reciprocates effort by adequate…Abstract Number: 1710 • 2012 ACR/ARHP Annual Meeting
Increase in Vitamin D Improves Disease Activity and Systolic Blood Pressure in Systemic Lupus Erythematosus
Background/Purpose: Vitamin D deficiency has also been associated with different chronic conditions including cardiovascular diseases such as coronary artery disease, cardiac failure and hypertension. In…Abstract Number: 932 • 2012 ACR/ARHP Annual Meeting
Medical Costs and Health Care Resource Use in Patients with Systemic Lupus Erythematosus in an Insured Population
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that may affect multiple organ systems. The clinical manifestations of SLE are heterogeneous, and subjects…Abstract Number: 1427 • 2012 ACR/ARHP Annual Meeting
Late Onset Systemic Lupus Erythematosus: Is It Actually A Milder Variant?
Background/Purpose: Classically, late onset Systemic Lupus Erythematosus (SLE) has been described as a milder variant of the disease. The objective of this study is to…Abstract Number: 886 • 2012 ACR/ARHP Annual Meeting
Association Between Neutrophil Gene Signature and Disease Characteristics in Systemic Lupus Erythematosus Patients
Background/Purpose: Neutrophils and neutrophil death (“netosis”) are now understood to play a role in the pathogenesis of SLE. A neutrophil gene signature exists in SLE,…