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Abstracts tagged "Statistical methods"

  • Abstract Number: 1812 • ACR Convergence 2022

    Impact of Misclassification on the US Prevalence of Gout: Bayesian Sensitivity Analysis of the National Health & Nutrition Examination Survey (NHANES)

    Lingxiao Chen1, Yue Zhang2 and Kazuki Yoshida3, 1Kolling Institute, Sydney, Australia, 2University of Utah, Salt Lake City, UT, 3Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Gout is considered the most common inflammatory arthritis in the US with an estimated prevalence of 3.9% based on the National Health and Nutrition…
  • Abstract Number: 2100 • ACR Convergence 2022

    Employment Trajectory of Canadian Young Adults with Systemic Lupus Erythematosus

    Lily Lim1, Menelaos Konstanidis2, Zahi Touma3, Diane Lacaille4, Umut Oguzoglu1, Christine Peschken1, Nicole Anderson3, Ramandeep Kaur1 and Eleanor Pullenayegum2, 1University of Manitoba, Winnipeg, MB, Canada, 2University of Toronto, Toronto, ON, Canada, 3Schroeder Arthritis Institute, Krembil Research Institute, University Health Network and University of Toronto, Toronto, ON, Canada, 4Arthritis Research Canada, University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: Young adulthood (18-30 years) is a time of many changes. Young adults finish school, enter the labour force, and maybe start their own families.…
  • Abstract Number: 2224 • ACR Convergence 2022

    Genes Causative of Primary Immunodeficiency Are Risk Factors for and Over-expressed in Systemic Lupus Erythematosus

    Haley Davis1, Adam Labonte1, Katherine Owen2, Erika Hubbard1, Jessica Kain1, Brian Kegerreis1, Prathyusha Bachali3, Amrie Grammer4 and Peter Lipsky1, 1AMPEL BioSolutions, Charlottesville, VA, 2RILITE, Crozet, VA, 3AMPEL BioSolutions, Redmond, WA, 4AMPEL LLC, Charlottesville, VA

    Background/Purpose: Systemic lupus erythematosus (SLE) is a polygenic autoimmune disease whose specific causes are incompletely understood and for which there exists no single comprehensive diagnostic…
  • Abstract Number: 1218 • ACR Convergence 2021

    Unsupervised Clustering Identifies Unique Subsets of Patients in a Racially and Ethnically Diverse Rheumatoid Arthritis Cohort

    Gabriella Lui1, Namrata Singh2, James Andrews3, Jonathan Graf4 and Katherine Wysham5, 1University of Washington Department of Bioengineering, Seattle, WA, 2University of Washington, Bellevue, WA, 3University of Washington, Seattle, WA, 4Ucsf, San Francisco, CA, 5VA Puget Sound/University of Washington, Seattle, WA

    Background/Purpose: Single biomarkers have limited utility to date in guiding clinical care in RA. There is growing interest in applying machine learning algorithms to combine…
  • Abstract Number: 1290 • ACR Convergence 2021

    Validation of a Novel Lupus Multivariable Outcome Score as an Outcome Measure for Systemtic Lupus Erythematosus Trials

    Michal Abrahamowicz1 and Peter Lipsky2, 1McGill University, Montréal, QC, Canada, 2AMPEL BioSolutions, Charlottesville, VA

    Background/Purpose: Development of effective new Systemic Lupus Erythematosus (SLE) treatments requires a validated responder index responsive to clinically meaningful change and relevant to clinical practice.…
  • Abstract Number: 0259 • ACR Convergence 2021

    JIA Diagnoses and Trends from 2006-2019: Has the U.S. ICD-9-to-ICD-10 Transition Created Coding Artifacts?

    Daniel Horton1, Lauren Parlett2, Cecilia Huang3, Stephen Crystal4, Amy Davidow5, Tobias Gerhard6, Carlos Rose7, Kevin Haynes2 and Brian Strom8, 1Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 2HealthCore, Wilmington, DE, 3Rutgers Institute for Health, New Brunswick, NJ, 4Rutgers School of Social Work, New Brunswick, NJ, 5Rutgers School of Public Health, New Brunswick, NJ, 6Ernst Mario School of Pharmacy, New Brunswick, NJ, 7Thomas Jefferson University, Wilmington, DE, 8Rutgers Biomedical and Health Sciences, Newark, NJ

    Background/Purpose: JIA is the most common rheumatic disease of childhood, but recent data on diagnostic trends in the US are lacking. Furthermore, the impact of…
  • Abstract Number: 0543 • ACR Convergence 2021

    Novel Insights into Systemic Sclerosis Using a Sensitive Computational Method to Analyze Whole-genome Bisulfite Sequencing Data

    Jeffrey Yu1, Tianyuan Lu1, Kaiqiong Zhao1, Kathleen Oros Klein1, Maximilien Lora2, Ines Colmegna3, Celia MT Greenwood4 and Marie Hudson2, 1Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, QC, Canada, 2McGill University, Montréal, QC, Canada, 3The Research Institute of the McGill University Health Centre, Montréal, QC, Canada, 4Epidemiology, Biostatistics and Occupational Health / Faculty of Medicine and Health Sciences / McGill University, Montréal, QC, Canada

    Background/Purpose: While the etiology of systemic sclerosis (SSc) remains largely unknown, epigenetic dysregulation including abnormal DNA methylation is thought to contribute to its onset and…
  • Abstract Number: 0759 • ACR Convergence 2021

    The Patient as Assessor of Disease Status: A Graphical Evaluation of Relations Between Patient-Reported Outcomes in Early Rheumatoid Arthritis

    Diederik De Cock1, Gert Verhavert1, Sofia Pazmino1, Delphine Bertrand1, Michal Doumen1, Rene Westhovens2 and Patrick Verschueren3, 1KU Leuven, Leuven, Belgium, 2University Hospitals KU Leuven, Maaseik, Belgium, 3University Hospitals Leuven - KULeuven, Leuven, Belgium

    Background/Purpose: Current EULAR-guidelines recommend treating Rheumatoid Arthritis (RA) early, intensively and to-target. Patient-Reported Outcomes (PROs) can be important contributors for remote monitoring of disease status…
  • Abstract Number: 0850 • ACR Convergence 2021

    Regression Methods for Modeling Western Ontario and McMaster Universities Arthritis Index (WOMAC) Pain Scores for Early Stage Knee Osteoarthritis

    Benjamin Sweigart and Michael LaValley, Boston University School of Public Health, Boston, MA

    Background/Purpose: The Western Ontario and McMaster Universities Arthritis Index (WOMAC) pain score [range 0-20] is a common outcome measure for clinical trials and observational studies…
  • Abstract Number: 0851 • ACR Convergence 2021

    Application of a Modified Recursive Feature Elimination Machine Learning Algorithm to Select Predictors of Mortality in Those with and Without Osteoarthritis

    Siyeon Kim1, Siqi Xiang1, Liubov Arbeeva1, Carolina Alvarez1, Amanda Nelson1, Yvonne Golightly1, Leigh Callahan2, Michael Kosorok1 and Becki Cleveland3, 1University of North Carolina at Chapel Hill, Chapel Hill, NC, 2University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC, 3Thurston Arthritis Research Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC

    Background/Purpose: Radiographic osteoarthritis (rOA) and joint symptoms at the knee and hip are predictors of mortality. However, questions remain about the nature of the relationship…
  • Abstract Number: 0106 • ACR Convergence 2020

    A Machine Learning-derived Radiomics Nomogram for Diagnosis of Osteoporosis and Osteopenia

    Qianrong Xie1, Yue Chen2, Yimei Hu3, Fanwei Zeng4, Pingxi Wang4, Lin Xu5, Jianhong Wu6, Jie Li1, Jing Zhu7, Ming Xiang8 and Fanxin Zeng9, 1Department of Clinical Research Center, Dazhou Central Hospital, Dazhou, China (People's Republic), 2Department of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China (People's Republic), 3Department of Orthopedics, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China (People's Republic), 4Department of bone disease, Dazhou Central Hospital, Dazhou, China (People's Republic), 5Department of medical imaging, Dazhou Central Hospital, Dazhou, China (People's Republic), 6Department of Rheumatology, Dazhou Central Hospital, Dazhou, China (People's Republic), 7Department of Rheumatology and Immunology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, China (People's Republic), 8Department of Orthopedics, Sichuan Provincial Orthopedic Hospital, Chengdu, China (People's Republic), 9Department of Clinical Research Center, Dazhou Central Hospital, Dazhou, Sichuan, China (People's Republic)

    Background/Purpose: To discriminate osteoporosis and osteopenia using a quantitative computed tomography (QCT) radiomics signatures and clinical variables.Methods: This retrospective study enrolled 635 patients with QCT images and clinical characteristics from November…
  • Abstract Number: 0487 • ACR Convergence 2020

    Association Between an Extended Lifestyle Score and Adverse Health-related Outcomes in People with Rheumatoid Arthritis: A Study of 5295 UK Biobank Participants

    Jordan Canning1, Stefan Siebert2, Bhautesh Jani1, Frances Mair1 and Barbara Nicholl1, 1University of Glasgow, Glasgow, Scotland, United Kingdom, 2University of Glasgow, Glasgow, United Kingdom

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterised by inflammation of the synovial joints. Traditional lifestyle factors, such as smoking and poor diet,…
  • Abstract Number: 0613 • ACR Convergence 2020

    Modeling the Effects of Covid-19 Protective Behaviors and Healthcare Delivery on the Health of Patients with Rheumatic Disease

    Kevin Kennedy1, Emily Sirotich2, Salman Surangiwala3, Maggie Larche2, Mitchell Levine1 and Jonathan Hausmann4, 1McMaster University, Hamilton, Canada, 2McMaster University, Hamilton, ON, Canada, 3Queen’s School of Medicine, Kingston, Canada, 4Boston Children's Hospital / Beth Israel Deaconess Medical Center, Cambridge, MA

    Background/Purpose: COVID-19 has caused global disruptions in the management of chronic illnesses. The extent to which patients with rheumatic disease have been affected by COVID-19…
  • Abstract Number: 1009 • ACR Convergence 2020

    Missing Data and Multiple Imputation in Rheumatoid Arthritis Registries Using Sequential Random Forest Method

    Ahmed Al-Saber1, Adeeba Al-Herz2, Jiazhu Pan1, Khulood Saleh3, Adel Al-Awadhi4, Waleed Al-Kandari3, Eman Hasan5, Aqeel Ghanem6, Mohammed Hussain5, Yaser Ali7, Ebrahim Nahar7, Ahmad Alenizi8, Sawsan Hayat7, Fatemah Abutiban9, Ali Aldei5, Amjad Alkadi10, Heba Alhajeri7, Husain Behbehani3, Naser Alhadhood3, Khaled Mokaddem5, Ahmed Khadrawy3, Ammad Fazal3, Agaz Zaman7, Ghada Mazloum7, Youssef Bartella5, Sally Hamed5 and Ramia Alsouk8, 1Department of Mathematics and Statistics, University of Strathclyde, Glasgow, United Kingdom, 2Al-Amiri Hospital, Kuwait City, Kuwait, 3Farwania Hosiptal, Farwania, Kuwait, 4Faculty of Medicine, Kuwait University, Jabria, Kuwait, 5Al-Amiri Hospital, Kuwait, Kuwait, 6Mubarak Al-Kabeer Hospital, Kuwait City, Kuwait, 7Mubarak Al-Kabeer Hospital, Hawally, Kuwait, 8Jahra Hospital, Jahra, Kuwait, 9Rheumatology Unit, Department of Medicine, Jaber Alahmed Alsabah hospital, State of Kuwait, Jahra, Kuwait, 10Sabah Hospital, Kuwait, Kuwait

    Background/Purpose: Missing data in clinical epidemiological researches violate the intention to treat principle, reduce statistical power and can induce bias if they are related to…
  • Abstract Number: 1419 • ACR Convergence 2020

    Clinical Disease Might Be Divided into Two Phenotypes in ANCA Associated Vasculitis; Results of a Cluster Analysis

    Elif Ediboglu1, Onay Gercik2, Emre Bilgin3, Dilek Solmaz4, Irfan Ocal5, Arzu Saglam6, Zeki Soypacacı2, Haluk Cinaklı5, Sedat Kiraz3, Ömer Karadağ7 and Servet Akar2, 1Izmir Katip Celebi University, Izmir, Izmir, Turkey, 2Izmir Katip Celebi University, Izmir, Turkey, 3Hacettepe University, Ankara, Turkey, 4Izmir Katip Celebi University, Department of Internal Medicine, Division of Rheumatology, Izmir, TURKEY, Izmir, Turkey, 5Izmir Katip Celebi University, Izmir, 6Hacettepe University, Ankara, 7Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara,, Ankara, Turkey

    Background/Purpose: One of the controversial matters in ANCA associated vasculitis is the definition of disease based on clinical characteristics since there is a remarkable overlap…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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