Abstracts tagged "spondyloarthritis"

Abstract Number: 1324 • ACR Convergence 2020
Risk Factors for Adverse Pregnancy Outcomes in Women with Spondyloarthritis: An Observational Study from Two European Multidisciplinary Pregnancy Clinics
Ana Rita Cruz-Machado¹, Francesca Crisafulli², Sofia Barreira³, Patricia Martins⁴, Maria Chiara Gerardi⁵, Matteo Filippini², Micaela Fredi², Roberto Gorla⁶, Maria Grazia Lazzaroni², Cecilia Nalli⁶, Marco Taglietti², Andrea Lojacono⁷, Sonia Zatti⁸, Monica Centeno⁹, Cláudia Araújo¹⁰, Luísa Pinto¹⁰, Franco Franceschini¹¹, Angela Tincani¹², Susana Capela¹ and Laura Andreoli², ¹Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal, ²Rheumatology and Clinical Immunology Unit, Spedali Civili and University of Brescia, Brescia, Lombardia, Italy, ³Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal, ⁴Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universit�rio Lisboa Norte - Hospital de Santa Maria, Set�bal, Portugal, ⁵Rheumatology and Clinical Immunology Unit, Spedali Civili and University of Brescia, Milano, Italy, ⁶Rheumatology and Clinical Immunology Unit, Spedali Civili and University of Brescia, Brescia, Italy, ⁷Obstetrics and Gynaecology, Spedali Civili and University of Brescia, Brescia, Italy, ⁸Obstetrics and Gynecology Unit, Spedali Civili and University of Brescia, Brescia, Lombardia, Italy, ⁹Departamento de Obstetrícia, Ginecologia e Medicina da Reprodução, Hospital de Santa Maria, CHULN, Lisbon, Portugal, ¹⁰Departamento de Obstetrícia, Ginecologia e Medicina da Reprodução, Hospital de Santa Maria, CHULN, Lisboa, Portugal, ¹¹Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy, ¹²Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Milano, Italy
Background/Purpose: Women with Spondyloarthritis (SpA) seem at increased risk for adverse pregnancy outcomes (APO), however limited data have been published so far. The aim of…
Abstract Number: 1375 • ACR Convergence 2020
Remission in Axial Spondyloarthritis: Is There a Difference Between NSAIDs and Biologics in the Real Life?
Charlotte Baert¹, Charlene Mouafo Toukam², Tatiana Sokolova³, Maria S. Stoenoiu⁴, Patrick Durez⁵, Laurent Meric De Bellefon² and Adrien Nzeusseu Toukap⁶, ¹Rheumatology department, St-Luc university hospitals, Brussels, Belgium, ²Rheumatology department; St-Luc University Hospitals, Brussels, Belgium, ³Rheumatology, Cliniques Universitaires Saint-Luc – Université catholique de Louvain (UCL) – Institut de Recherche Expérimentale et Clinique (IREC), Brussels, Belgium, ⁴1Department of Rheumatology, Cliniques Universitaires Saint-Luc, 2Institut de recherche expérimentale et cliniques (IREC), Brussels, Belgium, ⁵Division of Rheumatology, Cliniques Universitaires Saint-Luc, Bruxelles, Belgium, ⁶1Department of Rheumatology, Cliniques Universitaires Saint Luc, 2Institut de recherche expérimentale et clinique (IREC), Brussels, Belgium
Background/Purpose: Randomized-controlled trials (RCTs) done in axial spondyloarthritis (AxSpA) patients have shown that remission in Ankylosing Spondylitis and nonradiographic AxSpA patients treated without biologics (BIOL)…
Abstract Number: 1857 • ACR Convergence 2020
KIR3DL2 Is Not Overexpressed on CD4+ T Cells and NK Cells in Patients with Axial Spondyloarthritis csDMARD and bDMARD Naive
Guillaume Larid¹, Sophie Trijau¹, Clothilde Barral¹, Pierre Lafforgue¹ and Thao Pham², ¹Aix Marseille Univ, APHM, Rheumatology department, Marseille, France, ²Aix Marseille Univ, APHM, department of rheumatology, Marseille, France
Background/Purpose: Overexpression of KIR3DL2 on CD4+ T-cells and NK-cells has been reported in patients with ankylosing spondylitis (AS) HLAB27+. We aimed to 1) analyse KIR3DL2…
Abstract Number: 1884 • ACR Convergence 2020
Disease Activity in an Axial Spondyloarthritis Cohort During the COVID-19 Pandemic
Jean Liew¹, Maria Castillo², Ethan Zaccagnino², Patricia Katz³, Nigil Haroon⁴ and Lianne Gensler⁵, ¹University of Washington, Seattle, WA, ²UCSF, San Francisco, CA, ³University of California, San Francisco, Novato, CA, ⁴University of Toronto, Toronto, ON, Canada, ⁵University of California San Francisco, San Francisco, CA
Background/Purpose: Response to the global coronavirus disease (COVID-19) pandemic has resulted in shelter-in-place orders and major changes to how people go about their daily lives.…
Abstract Number: 2019 • ACR Convergence 2020
Preliminary Definition of a Positive MRI for Active Lesions in the Sacroiliac Joints Typical of Axial Spondyloarthritis
Walter Maksymowych¹, Xenofon Baraliakos², Ulrich Weber³, Pedro M Machado⁴, Susanne J Pedersen⁵, Joachim Sieper⁶, Stephanie Wichuk¹, Denis Poddubnyy⁷, Martin Rudwaleit⁸, Désirée van der Heijde⁹, Robert Landewé¹⁰, Joel Paschke¹¹, Mikkel Østergaard¹² and Robert G Lambert¹³, ¹University of Alberta, Edmonton, AB, Canada, ²Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany, ³University of South Denmark, Odense, Denmark, ⁴University College London, London, United Kingdom, ⁵Rigshospitalet University, Copenhagen, Denmark, ⁶Charité Universitätsmedizin Berlin, Berlin, Germany, ⁷Charité – Universitätsmedizin Berlin, Berlin, Germany, ⁸Department of Internal Medicine and Rheumatology, Klinikum Bielefeld, Germany, ⁹Leiden University Medical Center, Leiden, Netherlands, ¹⁰Amsterdam University Medical Center & Zuyderland Hospital, Amsterdam, Netherlands, ¹¹CARE Arthritis, Edmonton, AB, Canada, ¹²Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, ¹³University of Alberta and CARE Arthritis, Edmonton, AB, Canada
Background/Purpose: The ASAS definition of a positive MRI for inflammation (ASAS-MRI+) is intended for classification of patients as having axSpA but is often misused for…
Abstract Number: 0238 • ACR Convergence 2020
Gestational Desire and Certolizumab Pegol in Patients with Chronic Inflammatory Rheumatic Disease. Preliminary Results of the GESTAMAD Cohort
Laura Gonzalez Hombrado¹, Marina Salido Olivares², Maria Carmen Ortega de la O³, Pilar Navarro Alonso⁴, Patricia Castro Perez⁵, Ana Castilla⁶, Alvaro Garcia Martos⁷, Celia Arconada³, Angel Aragon Diez⁸, Carolina Marin huertas³ and Eva Maria Andres Esteban⁹, ¹Hospital Universitario del Tajo, MADRID, Spain, ²Hospital de Parla, Madrid, Spain, ³Hospital infanta Elena, Madrid, Spain, ⁴Hospital de Fuenlabrada, Madrid, Madrid, Spain, ⁵Hospital Universitario de Getafe, Madrid, Spain, ⁶Hospital Universitario La Paz, Madrid, Spain, ⁷Hospital Universitario del Tajo, Madrid, ⁸Hospital Universitario de Gerafe, Madrid, Spain, ⁹Rey Juan Carlos University, Madrid, Spain
Background/Purpose: INTRODUCTION The use of biological therapies during pregnancy has been contraindicated since the beginning of the use of these drugs. In recent years several…
Abstract Number: 0630 • ACR Convergence 2020
“No Benefit from a Strict Immobilization in Vertebral Osteomyelitis” Vertebral Immobilization and Neurological Complication in Acute Pyogenic Vertebral Osteomyelitis: SPONDIMMO, a Prospective Cohort of 250 Patients
Adrien Le Pluart¹, COIFFIER Guillaume², Christelle Darrieutort¹, CORMIER Grégoire³, GODOT Sophie⁴, Sebastien Ottaviani⁵, Gaetane Nocturne⁶, MEROT Oriane⁷, COUDERC Marion⁸, HOPPE Emmanuel⁹, MULLEMAN Denis¹⁰, Benoit Le Goff¹¹ and Geraldine Bart¹², ¹Nantes University Hospital Center, Nantes, France, ²Rennes University Hospital Center, Rennes, France, ³La Roche Sur Yon Hospital Center, La Roche Sur Yon, France, ⁴Paris Croix Saint Simon Hospital Center, Paris, France, ⁵Rheumatology Department, Bichat hospital, APHP, Paris, France, ⁶Rheumatology Department, Bicetre Hospital, APHP, France, Le Kremlin-Bicêtre, France, ⁷Saint Nazaire Hospital Center, Saint-Nazaire, Pays de la Loire, France, ⁸Clermont Ferrant University Hospital Center, Clermont Ferrand, France, ⁹Angers University Hospital Center, Angers, France, ¹⁰Tours University Hospital Center, Tours, France, ¹¹Nantes University Hospital, Nantes, Pays de la Loire, France, ¹²Rennes University Hospital Center, Rennes, Bretagne, France
Background/Purpose: Vertebral osteomyelitis (VO) can be associated with neurological complications. We showed in a previous study that they occurred in 40% of patients with VO.…
Abstract Number: 1028 • ACR Convergence 2020
Probabilistic Linkage of a Cohort of Individuals with Symptoms Suggestive of Early Spondyloarthritis and the French National Healthcare Database
Aya Ajrouche¹, Candice Estellat¹, Clementina Lopez-Medina², Anna Molto³, Adeline Ruyssen Witrand⁴, Pascal Claudepierre⁵, Florence Tubach⁶, Laure Gossec⁷ and Maxime Dougados⁸, ¹AP-HP, Hôpital Pitié-Salpêtrière, Département Santé Publique, Centre de Pharmacoépidémiologie (Cephepi), Sorbonne Université, INSERM, Institut Pierre Louis d’Epidémiologie et de Santé Publique, équipe PEPITES, CIC 1901, F75013, Paris, France, Paris, France, ²Rheumatology Department, Cochin Hospital, Paris, Paris, France, ³Rheumatology Department, Cochin Hospital, APHP, Paris, France, Paris, France, ⁴Rheumatology center, University Hospital of Toulouse, Inserm 1027, University Paul Sabatier, Toulouse, France, Toulouse, France, ⁵Hôpital Henri Mondor, Université Paris Est Créteil, EA 7379 EpiDermE, department of rheumatology, Créteil, France, ⁶Pierre Louis Institute of Epidemiology and Public Health, INSERM 1136, Sorbonne University and Centre of Pharmacoepidemiology, Pitié Salpêtrière Hospital, APHP.Sorbonne University, Paris, Ile-de-France, France, ⁷Sorbonne Université and Hôpital Universitaire Pitié Salpêtrière, Paris, France, ⁸Université de Paris, Department of Rheumatology, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Paris, France
Background/Purpose: DESIR is the French cohort of patients with symptoms suggestive of early axial Spondyloarthritis (axSpA). Our objective was to enrich this cohort with claims…
Abstract Number: 1327 • ACR Convergence 2020
Comorbidity Burden in Patients with Non-Radiographic Axial Spondyloarthritis at Least as High as in Ankylosing Spondylitis
Jonas Sagard¹, Elisabet Lindqvist², Elisabeth Mogard¹, Anna Jöud³, Mats Geijer⁴, Tor Olofsson¹ and Johan K. Wallman¹, ¹Department of Clinical Sciences Lund, Rheumatology, Lund University, Sweden. Department of Rheumatology, Skåne University Hospital, Lund, Sweden., Lund, Sweden, ²Department of Clinical Sciences Lund, Rheumatology, Lund University, Sweden. Department of Rheumatology, Skåne University Hospital. Lund, Sweden, Lund, Sweden, ³Department of Laboratory Medicine, Division of Occupational and Environmental Medicine, Lund University, Sweden., Lund, Sweden, ⁴Department of Radiology, Institute of Clinical Sciences, University of Gothenburg, Sahlgrenska Academy, Gothenburg, Sweden. Department of Radiology, Sahlgrenska University Hospital, Gothenburg, Sweden., Gothenburg, Sweden
Background/Purpose: Few studies have investigated the overall occurrence of comorbidities in patients with non-radiographic axial spondyloarthritis (nr-axSpA) in relation to ankylosing spondylitis (AS). Compared to…
Abstract Number: 1376 • ACR Convergence 2020
Impact of Body Composition Measures on the Response to Biological Disease-modifying Anti-rheumatic Drugs in Patients with Ankylosing Spondylitis
Valeria Rios Rodriguez¹, Mikhail Protopopov¹, Fabian Proft¹, Judith Rademacher¹, Burkhard Muche¹, Anne-Katrin Weber¹, Susanne Lüders¹, Hildrun Haibel¹, Maryna Verba¹, Joachim Sieper¹ and Denis Poddubnyy², ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²Charité – Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: Data on the impact of body weight and body mass index (BMI) on the response to biological disease-modifying anti-rheumatic drugs (bDMARDs) in axial spondyloarthritis…
Abstract Number: 1858 • ACR Convergence 2020
Increased Proportion of TH17, TH22 and TC17 Cells and the Correlation to IL-22 and Clinical Parameters in Patients with Ankylosing Spondylitis from Northern Sweden
Kristina Lejon¹, Urban Hellman², Lan Do², Anjani Kumar² and Helena Forsblad-d'Elia³, ¹Department of Clinical microbiology, Infection and Immunology, Umeå University, Umeå, Sweden, ²Department of Public Health and Clinical Medicine, Rheumatology, Umeå, Sweden, ³Department of Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Vasterbottens Lan, Sweden
Background/Purpose: Increased levels of TH17 and TH22 as well as TC17 and TC22 cells have previously been associated with ankylosing spondylitis (AS). The correlation between…
Abstract Number: 1887 • ACR Convergence 2020
Spinal Mobility and Function: How Closely Do They Associate in Axial Spondyloarthropathy?
Sinead Maguire¹, Phil Gallagher² and Finbar O'Shea¹, ¹St James' Hospital, Dublin, Ireland, ²St Vincents University Hospital, UCD, Dublin, Ireland
Background/Purpose: Axial spondyloarthropathy (axSpA) is a form of inflammatory arthritis affecting the axial skeleton. Persistent disease activity can result in restricted spinal mobility over time,…
Abstract Number: 2020 • ACR Convergence 2020
Preliminary Definition of a Positive MRI for Structural Lesions in the Sacroiliac Joints in Axial Spondyloarthritis
Walter Maksymowych¹, Xenofon Baraliakos², Ulrich Weber³, Pedro M Machado⁴, Susanne J Pedersen⁵, Joachim Sieper⁶, Stephanie Wichuk¹, Denis Poddubnyy⁷, Martin Rudwaleit⁸, Désirée van der Heijde⁹, Robert Landewé¹⁰, Joel Paschke¹¹, Robert G Lambert¹² and Mikkel Østergaard¹³, ¹University of Alberta, Edmonton, AB, Canada, ²Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany, ³University of South Denmark, Odense, Denmark, ⁴University College London, London, United Kingdom, ⁵Rigshospitalet University, Copenhagen, Denmark, ⁶Charité Universitätsmedizin Berlin, Berlin, Germany, ⁷Charité – Universitätsmedizin Berlin, Berlin, Germany, ⁸Department of Internal Medicine and Rheumatology, Klinikum Bielefeld, Germany, ⁹Leiden University Medical Center, Leiden, Netherlands, ¹⁰Amsterdam University Medical Center & Zuyderland Hospital, Amsterdam, Netherlands, ¹¹CARE Arthritis, Edmonton, AB, Canada, ¹²University of Alberta and CARE Arthritis, Edmonton, AB, Canada, ¹³Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: There is lack of international consensus as to what defines a structural lesion on MRI of the sacroiliac joints (SIJ) typical of axial spondyloarthritis…
Abstract Number: 0310 • ACR Convergence 2020
The Prediction of Psoriatic Arthritis Tool (PRESTO) Study – Interim Report
Lihi Eder¹, Ker-Ai Lee², Vinod Chandran³, Jessica Widdifield⁴, Aaron Drucker⁵, Christopher Ritchlin⁶, Cheryl Rosen⁷, Richard Cook² and Dafna Gladman³, ¹Women’s College Research Institute, University of Toronto, Toronto, ON, Canada, ²University of Waterloo, Waterloo, ON, Canada, ³Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, ⁴University of Toronto - Toronto, Toronto, ON, Canada, ⁵University of Toronto, Toronto, Canada, ⁶Department of Medicine, University of Rochester Medical Center, Rochester, NY, ⁷University of Toronto, Toronto, ON, Canada
Background/Purpose: A simple, scalable tool that identifies psoriasis patients at high risk for developing PsA could improve early detection and facilitate early intervention. Our overall…
Abstract Number: 0695 • ACR Convergence 2020
Chronic Inflammatory Back Pain Occurring Later in Life: A Neglected Concept
Lauren Ridley¹, Nahid Rianon², Mark Hwang³, MinJae Lee⁴, Lianne Gensler⁵, Michael Ward⁶, Matthew Brown⁷, Amirali Tahanan², Mohammad Rahbar², Mariko Ishimori⁸, Michael Weisman⁹ and John Reveille¹⁰, ¹McGovern Medical School at UTHealth, Houston, TX, ²McGovern Medical School at UTHealth, Houston, ³McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, ⁴UT Southwestern, Dallas, ⁵University of California San Francisco, San Francisco, CA, ⁶National Institutes of Health, Bethesda, MD, ⁷Guy's and St Thomas, NHS Foundation Trust and King's College London NIHR Biomedical Research Centre, King's College London, London, United Kingdom, London, United Kingdom, ⁸Cedars-Sinai Medical Center, Los Angeles, CA, ⁹Distinguished Professor of Medicine Emeritus, David Geffen School of Medicine at UCLA, LOS ANGELES, CA, ¹⁰Department of Internal Medicine, University of Texas, Houston, TX
Background/Purpose: Chronic back pain (CBP) is a common musculoskeletal complaint and a significant cause of disability (Weisman et al., 2013). A subset of CBP, chronic…

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