Abstract Number: 1816 • 2016 ACR/ARHP Annual Meeting
SLE and Uctd in the Rheumatology Informatics System for Effectiveness (RISE) Registry
Background/Purpose: The ACR-sponsored RISE (Rheumatology Informatics System for Effectiveness) Registry is an electronic health record (EHR)-based national database of rheumatology clinical visits. De-identified patient data…Abstract Number: 2810 • 2016 ACR/ARHP Annual Meeting
Correlates of Spontaneous Cytokine Production in Individuals Undergoing Interferon-Gamma Release Assay Testing
Background/Purpose: The interferon gamma (IFN-G) release assay (IGRA) estimates probability of latent TB infection (LTBI) based on IFN-G released by whole blood after 18h exposure…Abstract Number: 2936 • 2016 ACR/ARHP Annual Meeting
All-Trans Retinoic Acid Stabilizes Natural T Regulatory Cells Isolated from Patients with Systemic Lupus Erythematosus Under Inflammatory Conditions
Background/Purpose: Recent studies have demonstrated that naturally occurring CD4+Foxp3+regulatory T cells (nTregs) are unstable and dysfunctional in the presence of pro-inflammatory cytokines. All-trans RA (atRA),…Abstract Number: 121 • 2016 ACR/ARHP Annual Meeting
Systemic Lupus Erythematosus (SLE) Is a Salient Cause of Premature Mortality in the United States: A Sex-Based Exploration
Background/Purpose: The epidemiology of SLE has a complex gendered aspect, characterized by marked differences between the sexes in terms of the incidence, prevalence, and clinical…Abstract Number: 965 • 2016 ACR/ARHP Annual Meeting
Clinical and Serologic Variables Associated with Renal Response Among Lupus Nephritis Phase III Trial Patients Treated with Standard of Care Immunosuppression
Background/Purpose: Lupus nephritis (LN) is associated with high treatment failure rates and the development of new therapies for LN is limited by the lack of…Abstract Number: 1384 • 2016 ACR/ARHP Annual Meeting
Comparison of the Systemic Lupus Collaborating Clinics-Damage Index Score with a Physician Global Assessment of Damage in an International Cohort of Patients with Childhood-Onset Systemic Lupus
Background/Purpose: Childhood-onset systemic lupus erythematosus (cSLE) is a chronic autoimmune disease, which can affect any organ system. cSLE is associated with significant morbidity, including…Abstract Number: 1817 • 2016 ACR/ARHP Annual Meeting
A Longitudinal Analysis of Change in Lupus Disease Activity Pattern in Hopkins Lupus Cohort Using a Multistate Markov Model Approach
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a multi-systemic inflammatory disease with extreme variability of its activity over time. We have described three main patterns: long…Abstract Number: 2811 • 2016 ACR/ARHP Annual Meeting
Predictors of Persistent Disease Activity and Persistent Remission in Systemic Lupus Erythematosus – Results from the Hopkins Lupus Cohort
Background/Purpose: Systemic lupus erythematosus (SLE) is characterized by a variability of disease expression, both between individuals and within individuals, over time. The aim of this…Abstract Number: 2937 • 2016 ACR/ARHP Annual Meeting
Regulation of Follicular Helper T (TFH) Cells By ROCK2 (Rho-associated coiled-coil containing protein kinase 2)
Background/Purpose: Follicular helper T (TFH) cells promote humoral responses and serve as a limiting factor for the selection of high affinity germinal center B cells.…Abstract Number: 122 • 2016 ACR/ARHP Annual Meeting
A Small Number of Patients with SLE Account for Most of the Direct and Indirect Hospitalization Costs
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that can affect multiple organ systems and is associated with high morbidity. Studies have shown…Abstract Number: 966 • 2016 ACR/ARHP Annual Meeting
Renal Activity in Lupus (RAIL) Urinary Biomarkers Predict Treatment Response
Renal Activity In Lupus (RAIL) Urinary Biomarkers Predict Treatment Response Background/Purpose: We have previously demonstrated the strong predictive value of the Renal Activity In Lupus…Abstract Number: 1387 • 2016 ACR/ARHP Annual Meeting
Evaluation of Mild to Moderate SLE Flare in Patients with Childhood-Onset Disease
Background/Purpose: One aspect of childhood SLE lacking understanding is the prediction of disease flares. The objective of this study is to identify predictors of mild…Abstract Number: 1828 • 2016 ACR/ARHP Annual Meeting
Metabolic Reprogramming in CD4+CD28-CXCR3intt-bethi cells and Its Relevance to Pathogenesis in Patients with SLE
Background/Purpose: CD4+ T cells play a crucial role in pathological process of Systemic Lupus Erythematosus (SLE). Recently, importance of metabolic reprograming in immunocompetent cells was…Abstract Number: 2815 • 2016 ACR/ARHP Annual Meeting
Comparison of Lupus Nephritis Induction Therapy with Cyclophosphamide High Dose Versus Low Dose
Background/Purpose: To Compare the induction therapy of lupus nephritis with cyclophosphamide (CYC) high dose or low dose and identify possible predictors of disease remission. Methods:…Abstract Number: 2984 • 2016 ACR/ARHP Annual Meeting
Novel Anti-Malarial Drug Derivative Inhibited Type I Interferon Production and Autoimmune Inflammation through Inhibition of CGAS-Sting Pathway in Trex1-/- Mouse
Background/Purpose: Type I interferon, (IFN-I) is strongly implicated in the pathogenesis of SLE as well as rare monogenic ‘interferonopathies’ such as Aicardi-Goutieres Syndrome (AGS) caused…
- « Previous Page
- 1
- …
- 18
- 19
- 20
- 21
- 22
- …
- 38
- Next Page »