ACR Meeting Abstracts

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Abstracts tagged "skin"

  • Abstract Number: 0512 • ACR Convergence 2020

    Efficacy of Apremilast for the Treatment of Manifestations of Behçet’s Syndrome Other Than Oral Ulcers, Including Skin Lesions and Arthritis

    Gülen Hatemi1, Alfred Mahr2, Mitsuhiro Takeno3, Doyoung Kim4, Melike Melikoğlu1, Sue Cheng5, Sven Richter5, Michele Brunori6, Maria Paris5, Mindy Chen5 and Yusuf Yazici7, 1Istanbul University‒Cerrahpaşa, Cerrahpaşa Medical School and Behçet’s Disease Research Center, Istanbul, Turkey, 2Cantonal Hospital St. Gallen, St. Gallen, Switzerland, 3Nippon Medical School, Graduate School of Medicine, Tokyo, Japan, 4Yonsei University College of Medicine and Severance Hospital, Seoul, Republic of Korea, 5Amgen Inc., Thousand Oaks, 6Amgen Europe GmbH, Rotkreuz, Switzerland, 7New York University School of Medicine, New York

    Background/Purpose: Behçet’s syndrome is a chronic, multi-system inflammatory disorder characterized by painful and recurrent oral ulcers (OU) and other manifestations, such as skin lesions and…
  • Abstract Number: 0841 • ACR Convergence 2020

    CD6 Modulation Ameliorates Kidney and Skin Disease in a Spontaneous Murine Lupus Model

    Samantha Chalmers1, Sayra Garcia1, Rajalakshmy Ayilam Ramachandran2, Chandra Mohan2, Leal Herlitz3, Dalena Chu4, Jeanette Ampudia4, Cherie Ng5, Stephen Connelly4 and Chaim Putterman1, 1Albert Einstein College of Medicine, Bronx, NY, 2University of Houston, Houston, TX, 3Cleveland Clinic, Cleveland, OH, 4Equillium, Inc, San Diego, CA, 5Equillium, Inc, La Jolla, CA

    Background/Purpose: T cells are an important contributor to the pathogenesis of SLE and lupus nephritis, and thus present themselves as interesting therapeutic targets. CD6 is…
  • Abstract Number: 0845 • ACR Convergence 2020

    Hematopoietic Specific Deficiency of Rho Kinase Attenuates Neutrophil NETosis and UVB-induced Skin Inflammation

    Minghui Li1, Xing Lyu1, Yubin Li2, James Liao3, Victoria Werth4 and Ming-Lin Liu1, 1University of Pennsylvania, philadelphia, 2University of Pennsylvania and the Michael J. Crescenz VA Medical Center, Philadelphia, PA, 3University of Chicago, Chicago, 4University of Pennsylvania and Corporal Michael J. Crescenz Veterans Administration Hospital, Philadelphia

    Background/Purpose: Neutrophils are the most abundant leukocytes and the first to be recruited to the site of photodamage after ultraviolet B (UVB) exposure. We have…
  • Abstract Number: 2693 • 2018 ACR/ARHP Annual Meeting

    What Is the Effect of Cyclophosphamide Iv Pulse Therapy in Patients with Diffuse Cutaneous Systemic Sclerosis on Skin Involvement: An Observational Study

    Brigit Kersten, Nathan den Broeder, Frank van den Hoogen, Els van den Ende and Madelon Vonk, Rheumatology, Radboud University Medical Center, Nijmegen, Netherlands

    Background/Purpose: Patients with systemic sclerosis who have proximal skin involvement are classified as diffuse cutaneous systemic sclerosis (DcSSc). Patients with progressive skin involvement have worse prognosis.…
  • Abstract Number: 2716 • 2018 ACR/ARHP Annual Meeting

    A New Score to Predict Digital Ulcers Combining Clinical Data, Imaging and Patient History in Systemic Sclerosis

    Stefanie Friedrich1,2, Susanne Lueders3, Gerd R. Burmester4, Gabriela Riemekasten5 and Sarah Ohrndorf4, 1Department of of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin; Germany, Berlin, Germany, 2Department of Radiology, Charité University Hospital, Berlin; Germany, Berlin, Germany, 3Department of Gastroenterology and Rheumatology, Charité Universitätsmedizin Berlin, Berlin, Germany, 4Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany, 5Rheumatology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany

    Background/Purpose: Ischemic complications such as digital ulcers (DU) are a common complication in systemic sclerosis (SSc) patients. The aim of this study was to combine…
  • Abstract Number: 2682 • 2017 ACR/ARHP Annual Meeting

    Correlation between Capillaroscopic Patterns of Nailfold Microangiopathy and Three Different Methods to Assess Dermal Thickness in Systemic Sclerosis Patients

    Barbara Ruaro1, Alberto Sulli2, Carmen Pizzorni1, Elisa Alessandri1, Sabrina Paolino1, Massimo Ghio1, Veronica Tomatis3, Vanessa Smith4 and Maurizio Cutolo1, 1Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino, Genoa, Italy, Genoa, Italy, 2Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino, Genoa, Italy, Genova, Italy, 3Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, Genoa, Italy, 4Department of Rheumatology, Ghent University Hospital, Faculty of Internal Medicine, Ghent University, Ghent, Belgium, Ghent, Belgium

    Background/Purpose: Systemic sclerosis (SSc) is characterized by increase of dermal thickness (DT) and impairment of microvascular system (1). Several studies demonstrate that nailfold capillaroscopy (NVC)…
  • Abstract Number: 3176 • 2016 ACR/ARHP Annual Meeting

    Meta-Analysis of SSc Clinical Trials with Molecular Gene Expression Data Suggests Potential Combination Therapies

    Jaclyn N. Taroni1, Viktor Martyanov2 and Michael L. Whitfield2, 1Department of Molecular & Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH, 2Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH

    Background/Purpose: Clinical trials in SSc have tended to be underpowered and not meet clinical endpoints. Genome-wide gene expression measured in some studies can prove challenging…
  • Abstract Number: 844 • 2015 ACR/ARHP Annual Meeting

    Identification of Subclinical Skin Involvement By High Frequency Ultrasound in Systemic Sclerosis Patients

    Barbara Ruaro, Alberto Sulli, Elena Bernero, Marco A. Cimmino, Sabrina Paolino and Maurizio Cutolo, Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, IRCCS A.O.U. San Martino-IST, University of Genova, Genoa, Italy, Genoa, Italy

    Background/Purpose: Skin involvement may be evaluated in systemic sclerosis (SSc) by modified Rodnan skin score (mRSS), the validated method to distinguish between patients with limited…
  • Abstract Number: 2777 • 2014 ACR/ARHP Annual Meeting

    Clinical-Biological Spectrum and Therapeutic Management of Hypocomplementemic Urticarial Vasculitis: Data from a French Nationwide Study on 57 Patients

    Marie Jachiet1, Alain Le Quellec2, Alban Deroux3, Pascal Godmer4, Mikael Ebbo5, Leonardo Astudillo6, Beatrice Flageul7, Nicolas Dupin8, Selim Aractingi1, Loïc Guillevin for the French Vasculitis Study Group9, Luc Mouthon9 and Benjamin Terrier10, 1Dermatology, Cochin Hospital, Paris, France, 2Division of internal Medicine, Hôpital Saint-Eloi, Centre Hospitalier Universitaire de Montpellier, Montpellier, Montpellier, France, 3Internal Medicine, CHU Grenoble, Grenoble, France, 4Department of Internal Medicine, Centre Hospitalier Bretagne Atlantique de Vannes, Vannes, France, 5Internal Medicine, CHU, Marseille, France, 6Internal Medicine, CHU, Toulouse, France, 7Dermatology, Saint Louis, Paris, France, 8Service de Dermatologie, Hôpital Cochin, AP-HP, Paris, France, 9National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, Paris, France, 10National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris, France

    Background/Purpose Hypocomplementemic urticarial vasculitis (HUV), an uncommon vasculitis of unknown etiology, is rarely reported. It is also called anti-C1q vasculitis in the 2012 revised International…
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