Abstracts tagged "risk factors"

Abstract Number: 0682 • ACR Convergence 2025
Predictors of Severe Outcomes in Scleroderma Renal Crisis: Updated Results from a Single Center Study
Alex Luta¹, Saloni Mitchell² and Virginia Steen³, ¹Hospital for Special Surgery, New York, NY, ²Mount Sinai West and Morningside, New York, NY, ³Georgetown University School of Medicine, Washington, DC
Background/Purpose: Scleroderma Renal Crisis (SRC) is a severe manifestation of Systemic Sclerosis (SSc) associated with elevated morbidity and mortality. We aimed to address the challenges…
Abstract Number: 0437 • ACR Convergence 2025
Lipid Screening in Rheumatoid Arthritis: A Retrospective Cohort Study Highlighting Gaps in Cardiovascular Risk Prevention
Anokhi Saklecha¹, Amelia Khoo², Sierra Mendelsohn², Abhijeet Danve³, Mei Xue Dong⁴ and Lisa Suter², ¹Yale University, New Haven, CT, ²Yale School of Medicine, New Haven, CT, ³Section of Rheumatology, Department of Medicine, Yale School of Medicine, New Haven, CT, ⁴Yale-New Haven Medical Center, new haven, CT
Background/Purpose: Rheumatoid arthritis (RA) is associated with a 1.5 to 2 fold increased risk of cardiovascular disease (CVD) due to systemic inflammation and endothelial dysfunction.…
Abstract Number: 2658 • ACR Convergence 2025
Risk of Immune-Mediated Inflammatory Diseases and Other Safety Outcomes in Patients with T2DM and Obesity Initiating GLP-1 RA: A Propensity Score-Matched Multi-center Study using the TriNetX Global Network
Hsin-Hua Chen and Wen-Cheng Chao, Taichung Veterans General Hospital, Taichung, Taiwan (Republic of China)
Background/Purpose: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are increasingly prescribed for type 2 diabetes mellitus (T2DM) and obesity due to their beneficial metabolic effects. However,…
Abstract Number: 1884 • ACR Convergence 2025
The Importance of Adherence to Dietary Recommendations for Rheumatoid Arthritis Risk May Be Greater in Younger Individuals – Results from a Nested Case-Control Study
Rebecka Bäcklund¹, Ulf Bergström¹, Michele Compagno¹, Linnea arvidsson², Emil Rydell³, Emily Sonestedt¹ and Carl Turesson³, ¹Lund University, Malmö, Sweden, ²Lund University, Malmö, ³Lund University, Malmö, Sweden
Background/Purpose: Healthy eating habits might prevent the development of rheumatoid arthritis (RA). The impact of such lifestyle factors on the risk of RA may differ…
Abstract Number: 1478 • ACR Convergence 2025
Construction and Validation of a Prediction Model of Cognitive Dysfunction in Patients with Systemic Lupus Erythematosus
Bin Zhou¹, QIn Huang², Pan Wang³ and Qiguo Cui⁴, ¹Nanfang Hospital, Guangzhou, Guangdong, China (People's Republic), ²Nanfang Hospital, Guangzhou, China (People's Republic), ³southern medical university Nanfang Hospital, Guangzhou, China (People's Republic), ⁴Southern Medical Univercity Nanfang Hospital, guang zhou, China (People's Republic)
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs. Cognitive dysfunction (CD) is a common but often underestimated complication in…
Abstract Number: 0677 • ACR Convergence 2025
Increased incidence of sudden cardiac death in systemic sclerosis: estimate & correlates.
Jessica Fairley¹, Elizabeth Paratz², Dylan Hansen³, Susanna Proudman⁴, Joanne Sahhar⁵, Gene-Siew Ngian⁶, Diane Apostolopoulos⁶, Jennifer Walker⁷, Lauren Host⁸, Wendy Stevens¹, Andre La Gerche², Mandana Nikpour⁹ and Laura Ross¹, ¹The University of Melbourne, Melbourne, Victoria, Australia, ²St Vincent's Institute of Medical Research, Melbourne, Victoria, Australia, ³St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia, ⁴The University of Adelaide, Adelaide, Victoria, Australia, ⁵Monash Health, Melbourne, Victoria, Australia, ⁶Monash University, Melbourne, Victoria, Australia, ⁷Flinders University, Adelaide, Victoria, Australia, ⁸Fiona Stanley Hospital, Perth, Victoria, Australia, ⁹University of Sydney, School of Public Health, Faculty of Medicine and Health, Sydney, New South Wales, Australia; St Vincent’s Hospital Melbourne, Department of Rheumatology, Fitzroy, Victoria, Australia, Melbourne, Victoria, Australia
Background/Purpose: The incidence of sudden cardiac death (SCD) is suspected to be increased in systemic sclerosis (SSc). However, data describing SCD incidence in SSc are…
Abstract Number: 0436 • ACR Convergence 2025
Why Do Patients with Rheumatic Disease Have MACE and Thrombotic Events?
Andrea Mazariego and Maria Greenwald, Desert Medical Advances, Rancho Mirage, CA
Background/Purpose: Patients with rheumatic disease have an increased risk for thrombotic events and major adverse cardiac events (MACE) due to systemic inflammation. Bleeding time is…
Abstract Number: 2630 • ACR Convergence 2025
The Absence of DORIS Remission Is Associated with Greater Risk of Preterm Birth and Preeclampsia in SLE Pregnancies
Camila Hernández-Blanco¹, Philip Carlucci², Peter Izmirly³, Jessica Dai⁴, Mala Masson⁵, Michael Belmont¹, Amit Saxena⁶, Jane Salmon⁷, Justin Brandt¹ and Jill Buyon⁸, ¹NYU Langone Health, New York, NY, ²New York University School of Medicine, New York, NY, ³New York University Grossman School of Medicine, New York, NY, ⁴New York University Grossman School of Medicine, Tenafly, NJ, ⁵NYU Langone Medical Center- Division of Rheumatology, New York, NY, ⁶Division of Rheumatology, Department of Medicine, NYU Grossman School of Medicine, New York, NY, ⁷Hospital for Special Surgery, New York, NY, ⁸NYU Grossman School of Medicine, New York, NY
Background/Purpose: Systemic Lupus Erythematosus (SLE) primarily affects females of childbearing age and increases the risk of adverse pregnancy outcomes (APOs), particularly in non-White individuals and…
Abstract Number: 1842 • ACR Convergence 2025
Social Vulnerability Index, Type 2 Lupus Symptoms, and Select Dysregulated Immune Features Identify Stage 2 (Pre-classification) SLE in the Lupus Autoimmunity in Relatives (LAUREL) Follow-up Cohort
Melissa Munroe¹, Zoe Reed², Joel Guthridge², Diane Kamen³, Timothy Niewold⁴, Kendra Young⁵, Angel Weng⁵, Emma Wu⁵, Gary Gilkeson⁶, Michael Weisman⁷, Mariko Ishimori⁷, Daniel Wallace⁸, John Harley⁹, David Karp¹⁰, Jill Norris¹¹ and Judith James², ¹Oklahoma Medical Research Foundation; Progentec Diagnostics, Inc., Oklahoma City, OK, ²Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Medical University of South Carolina, Johns Island, SC, ⁴Hospital for Special Surgery, New York, New York, ⁵Colorado School of Public Health, Aurora, CO, ⁶Medical University of South Carolina, Charleston, SC, ⁷Cedars-Sinai Medical Center, LOS ANGELES, CA, ⁸Cedars Sinai Medical Center, Studio City, CA, ⁹US Department of Veterans Affairs Medical Center, Cincinnati, OH, ¹⁰UT Southwestern Medical Center, Dallas, TX, ¹¹Colorado School of Public Health, Denver, CO
Background/Purpose: Socioeconomic environmental factors are associated with SLE disease activity and early mortality and may contribute to disease progression in at-risk populations. Blood relatives (BRs)…
Abstract Number: 1469 • ACR Convergence 2025
Remission, Low Level Disease Activity State (LLDAS) and Relapse in Patients With Early-Onset, Adult-Onset and Late-Onset Systemic Lupus Erythematosus
Adriana Vázquez-Hernández¹, Emilio Godinez-Lazarini², Erik Cimé-Aké² and Hilda Fragoso-Loyo³, ¹Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Immunology and Rheumatology Department, Mexico City, Distrito Federal, Mexico, ²Instituto Nacional de Ciencias Médicas y Nutrición. Salvador Zubirán. Immunology and Rheumatology Department, Mexico City, Mexico, ³Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, Mexico City, Mexico
Background/Purpose: In systemic lupus erythematosus (SLE), differences have been observed between patients of different ages at onset. This study evaluates remission, low disease activity, and…
Abstract Number: 0633 • ACR Convergence 2025
Diffuse Alveolar Hemorrhage in ANCA-Associated Vasculitis (AAV) and Systemic Lupus Erythematosus (SLE): A Comparative Analysis
Sai Shanmukha Sreeram Pannala¹, Medha Rajamanuri², Srikar Sama³, Fares Saliba⁴, Omar Mourad⁵, Elizabeth Fagin⁶, Koushik Varma Sangaraju⁷, Veena Katikineni⁸ and Anastasia Slobodnick⁹, ¹Northwell health/Staten Island university Hospital, new york city, NY, ²Southern Illinois University School of Medicine, Springfield, IL, ³University of California San Francisco Fresno, Fresno, CA, ⁴Staten Island University Hospital, Staten Island, NY, ⁵Zucker School of Medicine at Hofstra/Northwell at Staten Island University Hospital, Staten Island, NY, ⁶Staten Island University Hospital, Teaneck, NJ, ⁷St. Luke's University Health Network, Bethlehem, PA, ⁸Desert Orthopaedic and Rheumatologic Institute, Apple Valley, CA, ⁹Northwell, Staten Island, NY
Background/Purpose: Diffuse alveolar hemorrhage (DAH) is a rare but severe complication in Systemic Lupus Erythematosus (SLE), occurring in up to one-third of cases at disease…
Abstract Number: 0425 • ACR Convergence 2025
High Density Lipoprotein Dysfunction in Juvenile Idiopathic Arthritis as Compared to Children without Rheumatologic Disease
Tahnee Spoden¹, Samira Nazzar Romero², Deborah McCurdy³, Alice Hoftman⁴, Sangmee Bae⁵, Jennifer Wang⁴, Ani Shahbazian⁴ and Christina Charles-Schoeman⁶, ¹UCLA, Los Angeles, CA, ²Nemours Children's Health, Orlando, ³UCLA Medical Center, Los Angeles, CA, ⁴UCLA, Los Angeles, ⁵UCLA Rheumatology, Los Angeles, CA, ⁶UCLA Medical Center, Santa Monica, CA
Background/Purpose: Cardiovascular disease remains the leading cause of mortality in patients with Rheumatoid Arthritis (RA). Normally, high density lipoprotein (HDL) acts in a cardioprotective capacity…
Abstract Number: 2509 • ACR Convergence 2025
Predicting future relapse with proteomics in ANCA-Associated Vasculitis
Evan Barnes¹, Nora Shepherd², Colebrooke Johnson¹, David O'Dea¹, Bohang Jiang³, Emily Hyle², Zachary Williams⁴, Zachary Wallace⁵ and Gary Reynolds⁶, ¹Massachusetts General Hospital, Boston, MA, ²Massachusetts General Hospital, Boston, ³MGH, Boston, MA, ⁴Massachusetts General Hospital, Nancy, KY, ⁵Massachusetts General Hospital, Newton, MA, ⁶Massachusetts General Hospital, Newcastle upon Tyne, United Kingdom
Background/Purpose: Outcomes for ANCA associated vasculitis (AAV) have been transformed in recent years with many patients achieving prolonged periods of remission. Guidelines advise continuing maintenance…
Abstract Number: 1832 • ACR Convergence 2025
Time-to-Event Analysis of Statin Use and Thrombotic Risk in Patients with Systemic Lupus Erythematosus: A Single-Center Retrospective Study
Christine Lenchur¹, Niurka Liranzo Tejera¹, Adal Abonamah¹, Takemichi Matsui¹, Emily Cosentino¹, Priscilla Abate Namnum², Olga Marushchak¹, Melissa Akselrad¹, Martin John³, Sophia Lutgen⁴, Celestine He⁵, Boluwatito Oladeinde³, Harleen Sidhu⁶, Emilia Bagiella⁵, Ian Wright⁵ and Chrisanna Dobrowolski⁵, ¹Mount Sinai Morningside/West Hospitals, Icahn School of Medicine at Mount Sinai, New York, NY, ²Mount Sinai Morningside/West Hospitals, Icahn School of Medicine at Mount Sinai, New York, ³Icahn School of Medicine at Mount Sinai, New York, ⁴Mount Sinai Morningside/West Hospitals, Icahn School of Medicine at Mount Sinai, New York City, NY, ⁵Icahn School of Medicine at Mount Sinai, New York, NY, ⁶Icahn School of Medicine at Mount Sinai/NYC H+H- Elmhurst, Queens, NY, Rego Park, NY
Background/Purpose: Patients with systemic lupus erythematosus (SLE) face elevated risk of thrombotic events (TEs) due to traditional cardiovascular factors and chronic inflammation. Statins may offer…
Abstract Number: 1467 • ACR Convergence 2025
Risk Factors Associated with Chronic Kidney Disease and End-Stage Kidney Disease in Patients with Newly Diagnosed Lupus Nephritis
Aakash V. Patel¹, Lingxiao Zhang², Hyon K. Choi³ and April Jorge⁴, ¹Massachusetts General Hospital, Harvard Medical School, Boston, MA, ²Massachusetts General Hospital, Boston, ³MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA, ⁴Massachusetts General Hospital, Boston, MA

Background/Purpose: Lupus nephritis (LN) affects over half of patients with systemic lupus erythematosus (SLE) and is associated with an increased risk for adverse kidney outcomes.…

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