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Abstracts tagged "Rheumatoid Factor"

  • Abstract Number: 2741 • 2017 ACR/ARHP Annual Meeting

    Rheumatoid Factor (RF) Levels Remain Persistently Elevated 24 Weeks after Interferon (INF) Free Direct Antiviral Agents (DAA) Therapy in the Majority of RF+ HCV Infected Persons

    Corinne Kowal1, Carey Shive2,3, Elizabeth Zebrowski4,5, Lenche Kostadinova1,6, Brianna Fuller1,6, Elane Reyes2, Kelsey Rife4, Amy Hirsch4, Anita Compan4, Shyam Kottilil7, Yngve Falck-Ytter6,8, Leonard H. Calabrese9, Donald Anthony4,6,10,11 and Maya Mattar6,12, 1Department of Medicine, Louis Stokes VA Medical Center, Cleveland, OH, 2Department of Medicine and Pathology, Case Western Reserve University, Cleveland, OH, 3VA Geriartic Research and Education Clinical Center (GRECC), Louis Stokes VA Medical Center, Cleveland, OH, 4Louis Stokes VA Medical Center, Cleveland, OH, 5Department of Medicine, Case Western Reserve University, Cleveland, OH, 6Case Western Reserve University, Cleveland, OH, 7IHV Clinical Research Unit, University of Maryland, Baltimore,, Baltimore, MD, 8Internal Medicine/ Division of gastroenterology, Louis Stokes VA Medical Center, Cleveland, OH, 9Rheumatic & Immunologic Disease and Infectious Disease, Cleveland Clinic Foundation, Cleveland, OH, 10Division of Medicine and Pathology, Divisions of Infectious and Rheumatic diseases, University Hospitals Cleveland Medical Center, Cleveland, OH, 11VA Geriatric Research and Education Clinical Center (GRECC), Cleveland, OH, 12Internal Medicine/ Division of Rheumatology, University Hospitals Cleveland Medical Center, Cleveland, OH

    Background/Purpose: Cryoglobulinemic vasculitis (CV) is an extrahepatic manifestation of chronic HCV infection. It varies in severity from mild to life threatening. Some but not all…
  • Abstract Number: 2916 • 2017 ACR/ARHP Annual Meeting

    The Presence of a Large Number of Autoantibodies at Baseline Is Favourable for Early Treatment Response but Unfavourable for Drug-Free Remission in RA Patients

    Emma de Moel1, Veerle Derksen1, LA Trouw1, Holger Bang2, R.J. Goekoop3, I Speyer4, TWJ Huizinga1, CF Allaart1, REM Toes1 and Diane van der Woude5, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Orgentec Diagnostika GmbH, Mainz, Germany, 3Haga Hospital, The Hague, Netherlands, 4Haaglanden Medical Center, The Hague, Netherlands, 5Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: The autoantibody response of seropositive RA is very diverse and consists of various numbers of isotypes and antibodies to multiple post-translational modifications. It is…
  • Abstract Number: 72 • 2017 ACR/ARHP Annual Meeting

    The Presence of IgM Rheumatoid Factor Impede Immunodetection of Tnfa on Circulating Extracellular Vesicles Obtained from Rheumatoid Arthritis Patients

    Onno J. Arntz1, Bartijn C.H. Pieters1, Rogier Thurlings2, Peter M. van der Kraan3, F van den Hoogen2 and Fons A.J. van de Loo3, 1Experimental Rheumatology, Radboudumc, Nijmegen, Netherlands, 2Rheumatology, Radboudumc, Nijmegen, Netherlands, 3Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands

    Background/Purpose: Tumor-necrosis factor (TNF)-α plays a key role in the pathophysiology of rheumatoid arthritis (RA) and membrane bound TNFα is sufficient to induce arthritis in…
  • Abstract Number: 239 • 2017 ACR/ARHP Annual Meeting

    Ultrasound Abnormalities Predict Arthritis Development in ACPA and/or RF Positive Arthralgia Patients

    Annelies Blanken1, Marian van Beers-Tas1, Marlies Meursinge Reynders1 and Dirkjan van Schaardenburg1,2, 1Amsterdam Rheumatology and immunology Center | Reade, Amsterdam, Netherlands, 2Amsterdam Rheumatology and immunology Center | Academic Medical Center, Amsterdam, Netherlands

    Background/Purpose: Early diagnosis of rheumatoid arthritis (RA) is important for controlling disease activity and preventing joint damage. Individuals positive for anticitrullinated protein antibodies (ACPA) and/or…
  • Abstract Number: 480 • 2017 ACR/ARHP Annual Meeting

    ANTI-Carbamylated Protein Antibodies (CARP) in Palindromic Rheumatism: Prevalence and Clinical Significance

    Raul Castellanos-Moreira Sr.1, Virginia Ruiz-Esquide1, María José Gomara2, Sonia Cabrera-Villalba1, Sebastian C Rodriguez-Garcia1, Georgina Salvador3, Andrea Cuervo1, Julio Ramírez1, M. Victoria Hernández1, Juan Cañete1, Isabel Haro2 and Raimon Sanmartí1, 1Rheumatology Service, Hospital Clínic de Barcelona, Barcelona, Spain, 2Unit of Synthesis and Biomedical Applications of Peptides, IQAC-CSIC, Barcelona, Spain, 3Hospital Universitario Mutua Terrassa, Barcelona, Spain

    Background/Purpose: Autoantibodies (RF or ACPA) are found in sera from patients with palindromic rheumatism (PR) but there are no studies analyzing the presence of Anti-carbamylated…
  • Abstract Number: 27 • 2016 ACR/ARHP Annual Meeting

    A Rheumatologist’s Assessment of Therapy Responses (Rxresp) and Rheumatoid Factor Status (neg/pos) in 1995 Predicted Mortality through 2015 in a Community-Based Cohort of Incident Rheumatoid Arthritis Cases and Matched Control Subjects

    Alfonse T. Masi1, Azeem A. Rehman2, Laura Jorgenson3 and Jean C. Aldag3, 1University of Illinois, College of Medicine at Peoria, Peoria, IL, 2Neurosurgery, University of West Virginia Medical School, Morgantown, WV, 3Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL

    Background/Purpose: Greater disease severity, older age, positive serum rheumatoid factor (RF), and long-standing glucocorticoid usage contribute to increased mortality of rheumatoid arthritis (RA) patients. This…
  • Abstract Number: 491 • 2016 ACR/ARHP Annual Meeting

    Anti-Citrullinated Peptide Antibodies Testing Rate over Time in Newly Diagnosed RA Patients – Data from Three Administrative Claims Databases (2007–2014)

    E Alemao, Z Guo and L Burns, Bristol-Myers Squibb, Princeton, NJ

    Background/Purpose: Current clinical guidelines recommend testing for anti-citrullinated protein antibodies (ACPA) at the time of RA diagnosis.1 However, there is a lack of information about…
  • Abstract Number: 494 • 2016 ACR/ARHP Annual Meeting

    Sensitivity and Specificity of 14-3-3η, Anti-CEP-1 and Anti-Sa Antibodies in a Cohort of Seronegative and Suspected Rheumatoid Arthritis (RA) Patients from a Community Rheumatology Practice

    Dmitry Karayev1, Guoqiu Shen1, Yvonne Lam1, Andrew Rimmer1, Nayan Lal1, Eugene Karayev1, Kristine Azarraga1, Ronald A. Blum1, Allan L. Metzger1, Robert I. Morris1 and Arash A. Horizon2, 1Rheumatology Diagnostics Laboratory, Inc. (RDL), Los Angeles, CA, 2Center for Rheumatology Medical Group, Los Angeles, CA

    Background/Purpose: RA is the most common autoimmune inflammatory joint disease, affecting up to 1% of the world population. Detection of antibodies, specifically against IgM rheumatoid…
  • Abstract Number: 496 • 2016 ACR/ARHP Annual Meeting

    Impact of Anti-Citrullinated Protein Antibody and/or Rheumatoid Factor on Rheumatoid Arthritis Manifestations and Outcomes

    Ee Tzun Koh1, Angela Marie Chan1, Wei Qiang See2, Wenwei Xiang2, Khai Pang Leong1 and Tan Tock Seng Rheumatoid Arthritis Study Group, 1Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore, Singapore, 2Clinical Research and Innovation Office, Tan Tock Seng Hospital, Singapore, Singapore

    Background/Purpose: RA Patients with anti-citrullinated protein antibody (ACPA) or rheumatoid factor (RF) are known to have worse clinical outcomes compared to seronegative patients. To determine…
  • Abstract Number: 505 • 2016 ACR/ARHP Annual Meeting

    The Longitudinal Stability of the RA Biomarkers RF and ACPA in Classifying RA Subtypes over Extended Follow up

    Carl Orr, Francis Young and Douglas J. Veale, Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, University College Dublin, Dublin 4, Ireland

    Background/Purpose: In recent years several studies suggest that first order stratification of RA should be based on the presence or absence of rheumatoid factor (RF)…
  • Abstract Number: 552 • 2016 ACR/ARHP Annual Meeting

    Disability in Early Rheumatoid Arthritis, Course and Predictors  

    Therese Hansson1,2, Christina Book1,2, Lennart T.H. Jacobsson1,3 and Carl Turesson1,2, 1Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, 2Department of Rheumatology, Skåne University Hospital, Malmö, Sweden, 3Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden

    Background/Purpose: Patient reported outcome measures (PROMs), including the Health Assessment Questionnaire Disability Index (HAQ-DI), are valuable and reliable instruments for assessment of disease severity and…
  • Abstract Number: 579 • 2016 ACR/ARHP Annual Meeting

    MRI-Detected Osteitis Is Not Associated with the Presence or Level of ACPA Alone, but with the Combined Presence of ACPA and RF

    Debbie M. Boeters1, Wouter P. Nieuwenhuis1, Marije K. Verheul1, Elize C. Newsum1, Monique Reijnierse2, René E.M. Toes1, Leendert A. Trouw1 and Annette H.M. van der Helm-van Mil1, 1Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Radiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Within rheumatoid arthritis (RA) bone marrow edema (BME, osteitis) and anti-citrullinated protein antibodies (ACPAs) are associated with radiographic progression. ACPA has been associated with…
  • Abstract Number: 988 • 2016 ACR/ARHP Annual Meeting

    Risk of Rheumatoid Arthritis after Transfusion of Blood from Donors Later Diagnosed with  Rheumatoid Arthritis: A Retrospective Cohort Study

    Søren Andreas Just1, Kjell Titlestad2, Gustaf Edgren3, Klaus Rostgaard4, Johan Askling5, Hanne Lindegaard1 and Henrik Hjalgrim4, 1Department of Rheumatology, Department of Rheumatology, Odense University Hospital, Odense, Denmark, Odense, Denmark, 2Department of Clinical Immunology, Department of Clinical Immunology, Odense Unversity Hospital, Odense, Denmark, Odense, Denmark, 3Department of Medical Epidemiology and Biostatistics, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Stockholm, Sweden, 4Epidemiology Research, Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark, Copenhagen, Denmark, 5Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm, Sweden

    Background/Purpose: Rheumatoid Arthritis (RA) is a disease that can have a long sub-clinical phase. During this phase the person with pre-RA could have factors in…
  • Abstract Number: 1589 • 2016 ACR/ARHP Annual Meeting

    Body Mass Index Does Not Impact Abatacept Retention in Biologic-Naive Patients with Rheumatoid Arthritis Who Have Poor Prognostic Factors: A 12-Month Interim Analysis of an Observational, Prospective Study

    R Alten1, H-M Lorenz2, HG Nüßlein3, X Mariette4, M Galeazzi5, A Cantagrel6, M Chartier7, Y Elbez8, C Rauch9 and M Le Bars7, 1Schlosspark-Klinik University Medicine, Berlin, Germany, 2University Hospital, Heidelberg, Germany, 3University of Erlangen, Nürnberg, Germany, 4Université Paris-Sud, Paris, France, 5University of Siena, Siena, Italy, 6Purpan Hospital, Toulouse, France, 7Bristol-Myers Squibb, Rueil-Malmaison, France, 8Excelya, Boulogne-Billancourt, France, 9Bristol-Myers Squibb, Munich, Germany

    Background/Purpose: In patients with RA, obesity may impair clinical response to anti-TNF agents.1,2 In contrast, BMI does not appear to impact treatment retention or clinical…
  • Abstract Number: 1603 • 2016 ACR/ARHP Annual Meeting

    Clinical Responses to Tocilizumab Analyzed By Serologic Status in Rheumatoid Arthritis

    Laura Cappelli1, J. Lynn Palmer2 and Clifton Bingham III3, 1Medicine/Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 2CORRONA Research Foundation, Phoenix, AZ, 3Johns Hopkins University, Baltimore, MD

    Clinical Responses to Tocilizumab Analyzed by Serologic Status in Rheumatoid Arthritis Background/Purpose: Biologic medications have improved outcomes for patients with rheumatoid arthritis (RA), but little…
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Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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