ACR Meeting Abstracts

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Abstracts tagged "Rheumatoid Factor"

  • Abstract Number: 2607 • 2015 ACR/ARHP Annual Meeting

    Anti-Cyclic Citrullinated Peptide Antibodies and Rheumatoid Factor in Rheumatoid Arthritis Hispanics Exposed to Biomass Smoke

    Raymundo Vera-Pineda1, Alberto Cardenas-de La Garza2, Jorge Esquivel-Valerio3, Dionicio A. Galarza-Delgado2, Jose Ramon Azpiri-Lopez4, Iris J. Colunga-Pedraza2, Mario Alberto Garza-Elizondo2 and Jesus Zacarias Villarreal-Pérez5, 1Cardiology., Hospital Universitario, UANL., Monterrey, Mexico, 2Rheumatology, Hospital Universitario, UANL., Monterrey, Mexico, 3Rheumatology, Hospital Universitario.UANL, Monterrey, Mexico, 4Cardiology, Hospital Universitario, UANL., Monterrey, Mexico, 5Endocrinology, Hospital Universitario, UANL., Monterrey, Mexico

    Background/Purpose: Tobacco smoke has been associated to anti-cyclic citrullinated peptide (anti-CCP) antibodies positivity. Recently, in wood-smoke-induced chronic obstructive pulmonary disease (COPD) patients without rheumatoid arthritis…
  • Abstract Number: 515 • 2015 ACR/ARHP Annual Meeting

    Are Changes in Autoantibody Levels Reflecting Change in Prognosis of Rheumatoid Arthritis?

    Manuel Unger1, Farideh Alasti1, Paul Studenic1, Josef S. Smolen2,3 and Daniel Aletaha1, 1Department of Internal Medicine 3, Division of Rheumatology, Medical University Vienna, Vienna, Austria, 22nd Department of Medicine, Hietzing Hospital, Vienna, Austria, 3Department of Medicine 3, Division of Rheumatology, Medical University Vienna, Vienna, Austria

    Background/Purpose: The presence of rheumatoid factor (RF) and antibodies against citrullinated peptides (ACPA) is associated with progression of joint damage in patients with rheumatoid arthritis…
  • Abstract Number: 2660 • 2015 ACR/ARHP Annual Meeting

    Elevated 14-3-3η Serum Protein Levels Increase RA Confirmation Rates in Recent-Onset Polyarthritis Patients

    Nathalie Carrier1, Anthony Marotta2, Artur de Brum-Fernandes3,4, Patrick Liang3,4, Ariel Masetto5,6, Yuan Gui2, Jane Savill2, Sara Michienzi2, Henri Ménard7, Walter Maksymowych8 and Gilles Boire4, 1Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, 2Augurex Life Sciences Corp., Vancouver, BC, Canada, 3Department of Medicine/Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, 4Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada, 5Department of Medicine/Division of Rheumatology, Université de Sherbrooke, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada, 6Department of Medicine/Division of Rheumatology, University of Sherbrooke, Sherbrooke, QC, Canada, 7MSK Research Axis, McGill University Health Center Research Institute, Montreal, QC, Canada, 8Department of Medicine, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: The 14-3-3 family of conserved regulatory proteins consists of seven isoforms: α/β, γ, δ/ζ, ε, η, θ/τ and σ. These proteins exist as intracellular…
  • Abstract Number: 551 • 2015 ACR/ARHP Annual Meeting

    Baseline Autoantibodies Preferentially Impact Abatacept Efficacy in Patients with RA Who Are Biologic Naïve: 6-Month Results from a Real-World, International, Prospective Study

    R Alten1, HG Nüßlein2, M Galeazzi3, H-M Lorenz4, X Mariette5, A Cantagrel6, M Chartier7, G Desachy8, C Poncet9, C Rauch10 and M Le Bars11, 1Schlosspark-Klinik University Medicine, Berlin, Germany, 2University Erlangen, Nürnberg, Germany, 3University of Siena, Siena, Italy, 4University Hospital, Heidelberg, Germany, 5Université Paris-Sud, Paris, France, 6Purpan Hospital, Toulouse, France, 7Chiltern International, Neuilly, France, 8Excelya, Boulogne-Billancourt, France, 9Docs International, Nanterre, France, 10Bristol-Myers Squibb, Munich, Germany, 11Bristol-Myers Squibb, Rueil-Malmaison, France

    Background/Purpose: In a recent meta-analysis, neither rheumatoid factor (RF) nor anti-cyclic citrullinated peptide (anti-CCP) antibody status were associated with clinical response to treatment with anti-TNF…
  • Abstract Number: 2676 • 2015 ACR/ARHP Annual Meeting

    Is It Useful to Determine All Rheumatoid Factors Isotypes to Enhance Rheumatoid Arthritis Detection?  a Clinical Laboratory Perspective

    Alejandro Garza-Alpirez1, Mario Alberto Garza-Elizondo2, David Vega-Morales2, Cassandra Skinner-Taylor2, Ricardo Ramírez3, Roberto Negrete-López4, Jorge Esquivel-Valerio2, Miguel Villarreal-Alarcon2 and Andrés Mendiola1, 1Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario " Dr. José Eleuterio González". Universidad Autónoma de Nuevo León, Monterrey, Mexico, 2Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, Mexico, 3Rheumatology, Hospital Universitario, UANL., Monterrey, Mexico, 4Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario, Monterrey, Mexico

    Background/Purpose: Rheumatoid arthritis (RA) diagnosis includes determination of autoantibodies and, their presence can represents 33% (2/6) to 50% (3/6) of the 2010 ACR/EULAR classification criteria…
  • Abstract Number: 584 • 2015 ACR/ARHP Annual Meeting

    Positivity for Rheumatoid Factor Is Associated with a Better Short-Term Response and Long-Term Drug Retention of Abatacept: Results from Consecutive 508 Patients with Rheumatoid Arthritis in a Japanese Multicenter Registry

    Nobunori Takahashi1, Toshihisa Kojima1, Koji Funahashi2 and Naoki Ishiguro3, 1Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya, Japan, 2Nagoya University Hospital, Nagoya, Japan, 3Department of Orthopedic Suregery, Nagoya University Hospital, Nagoya, Japan

    Background/Purpose: Abatacept (ABT) is a biologic drug and has been available for rheumatoid arthritis (RA) patients since 2010 in Japan. There have still been few…
  • Abstract Number: 623 • 2015 ACR/ARHP Annual Meeting

    Seronegative Sjögren’s Syndrome Is Characterized By a Lower Prevalence of B-Cell Related Clinical Manifestations and a Lower Biologic Systemic Activity

    Luca Quartuccio1, Chiara Baldini2,3,4, Elena Bartoloni Bocci5, Roberta Priori6, Francesco Carubbi7, Laura Corazza1, Alessia Alunno8, Serena Colafrancesco6, Nicoletta Luciano2, Roberto Gerli9, Roberto Giacomelli10, Guido Valesini11, Stefano Bombardieri12 and Salvatore De Vita13,14, 1S. Maria della Misericordia, University of Udine, Italy, Udine, Italy, 2Internal Medicine, University of Pisa, Pisa, Italy, 3University of Pisa, Rheumatology Unit, Pisa, Italy, 4Department of Internal Medicine, Rheumatology Unit, University of Pisa, Pisa, Italy, 5Rheumatology Unit, Department of Medicine, University of Perugia, Pila, Italy, 6Rheumatology Unit, Sapienza University of Rome, Rome, Italy, 7Rheumatology Clinic, University of L'Aquila, L'Aquila, Italy, 8Clinical and Experimental Medicine, Rheumatology Unit, University of Perugia, Perugia, Italy, 9Rheumatology Clinic, University of Perugia, Perugia, Italy, 10University of L'Aquila, L'Aquila, Italy, 11Internal Medicine and Medical Specialties Department, Policlinico Umberto I, La Sapienza University of Rome, Roma, Italy, 12Rheumatology Unit, University of Pisa, Italy, Pisa, Italy, 13Santa Maria della Misericordia Hospital, University of Udine, Udine, Italy, 14Rheumatology, DSMB, University Hospital Santa Maria della Misericordia, Udine, Italy

    Background/Purpose: The American-European Consensus Group (AECG) Criteria (1) for Sjögren's syndrome (SS) require the presence of at least one of the following two conditions: the…
  • Abstract Number: 626 • 2015 ACR/ARHP Annual Meeting

    Efficacy of Belimumab and Targeting of Rheumatoid Factor Positive B-Cells in Sjögren’s Syndrome: Follow-up of the Open-Label Phase II Study

    Luca Quartuccio1, Sara Salvin2, Laura Corazza1, Saviana Gandolfo2, Martina Fabris3 and Salvatore De Vita4, 1S. Maria della Misericordia, University of Udine, Italy, Udine, Italy, 2Rheumatology Clinic, University of Udine, Udine, Italy, 3Clinic of Rheumatology, University of Udine, Udine, Italy, 4Santa Maria della Misericordia Hospital, University of Udine, Udine, Italy

    Background/Purpose: Belimumab, a monoclonal anti-B lymphocyte Stimulator (BLyS) antibody is preliminary found to be effective in Sjögren’s syndrome (SS) patients with moderate to high systemic…
  • Abstract Number: 1207 • 2015 ACR/ARHP Annual Meeting

    Predictive Utility of Anti- Citrullinated Peptide Antibodies and Rheumatoid Factor – a Retrospective Dataanalysis

    Miriam Gärtner, Mathias Schneeweiss, Josef S. Smolen and Klaus Machold, Department of Rheumatology, Medical University of Vienna, Vienna, Austria

    Background/Purpose: Antibody profiling encompassing rheumatoid factor (RF) and anti-citrullinated peptide antibodies (ACPA) supports diagnosis in patients with Rheumatoid arthritis (RA). However, RF and ACPA are…
  • Abstract Number: 1559 • 2015 ACR/ARHP Annual Meeting

    Clinical Characteristics and Medication Use Among Arab Patients with Rheumatoid Arthritis in Some Arab States

    Karim Bayoumy1, Soha Roger Dargham1, Wessam Elhaq1, Samar Al Emadi2, Mohammed Hammoudeh2, Basel Masri3, Hussein Halabi4, Humeira Badsha5, Imad Uthman6, Salah Mahdy2, Robert Plenge7, Richa Saxena7, Marianthi Kapiri1 and Thurayya Arayssi8, 1Weill Cornell Medical College in Qatar, Doha, Qatar, 2Medicine, Hamad Medical Corporation, Doha, Qatar, 3Jordan Hospital, Amman, Jordan, 4Medicine, King Faisal Specialist Hospital and research center, Jeddah, Saudi Arabia, 5Al Biraa Arthritis and Bone Clinic, Dubai, United Arab Emirates, 6Internal Medicine, American University of Beirut, Beirut, Lebanon, 7The Broad Institute of MIT and Harvard, Program of Medical and Population Genetics, Cambridge, MA, 8Internal Medicine, Weill Cornell Medical College in Qatar, Doha, Qatar

    Background/Purpose: Data on the clinical and genetic characteristics of Arab patients with Rheumatoid Arthritis (RA) is limited. Our aim is to report on the clinical…
  • Abstract Number: 1578 • 2015 ACR/ARHP Annual Meeting

    Serum Rheumatoid Factor and Anti-Cyclic Citrullinated Peptide Antibody Are Associated with Subclinical Interstitial Lung Disease in the Multi-Ethnic Study of Atherosclerosis: A Population-Based Study

    Elana J. Bernstein1, R. Graham Barr2, John H.M. Austin3, Steven M. Kawut4, Ganesh Raghu5, Jessica L. Sell6, Eric A. Hoffman7, John D. Newell Jr.8, Jubal R. Watts Jr.9, P. Hrudaya Nath10, Sushil K. Sonavane9, Joan M. Bathon1, Darcy S. Majka11 and David J. Lederer2, 1Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 2Medicine, Columbia University College of Physicians & Surgeons, New York, NY, 3Radiology, Columbia University College of Physicians & Surgeons, New York, NY, 4Division of Pulmonary, Allergy, and Critical Care, University of Pennsylvania, Philadelphia, PA, 5University of Washington, Seattle, WA, 6Columbia University College of Physicians & Surgeons, New York, NY, 7University of Iowa, Iowa City, IA, 8Radiology, University of Iowa, Iowa City, IA, 9Radiology, University of Alabama at Birmingham, Birmingham, AL, 10University of Alabama at Birmingham, Birmingham, AL, 11Division of Rheumatology, Northwestern University, Chicago, IL

    Background/Purpose: Approximately 30% of adults diagnosed with interstitial lung disease (ILD) have an underlying established autoimmune disease. Based on the strong links between autoimmunity and…
  • Abstract Number: 1607 • 2015 ACR/ARHP Annual Meeting

    Rheumatoid Factor Is Associated with the Distribution of Hand Joint Destruction in a Dose-Dependent Manner

    Chikashi Terao1, Noriyuki Yamakawa2, Koichiro Yano3, I.M. Markusse4, Katsunori Ikari3, Shinji Yoshida3, Moritoshi Furu5, Motomu Hashimoto5, Hiromu Ito5, Takao Fujii6, Koichiro Ohmura7, Kosaku Murakami7, Meiko Takahashi2, Masahide Hamaguchi8, Yasuharu Tabara2, Atsuo Taniguchi3, Shigeki Momohara3, Soumya Raychaudhuri9, Cornelia F. Allaart10, Hisashi Yamanaka11, Tsuneyo Mimori12 and Fumihiko Matsuda13, 1Departments of Genetics and Rheumatology, Brigham and Women's Hospital, Boston, MA, 2Kyoto University Graduate School of Medicine, Kyoto, Japan, 3Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 4LUMC, Leiden, Netherlands, 5Department of the Control for Rheumatic Diseases, Department of the Control for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 6Dept of Rheum/Clinical Immun, Kyoto University Graduate School of Medicine, Kyoto, Japan, 7Dept of Rheum & Clinical Immun, Kyoto Univ Grad School of Med, Kyoto, Japan, 8Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan, 9Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, 10Rheumatology, LUMC, Leiden, Netherlands, 11Tokyo Women's Medical University, Tokyo, Japan, 12Dept of Rheum & Clinical Immun, Kyoto Univ Grad Schl of Med, Kyoto, Japan, 13Genomic Center, Kyoto University Graduate School of Medicine, Kyoto, Japan

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic disease leading to joint destruction. Although many studies have addressed correlates associated with the speed of joint destruction,…
  • Abstract Number: 1658 • 2015 ACR/ARHP Annual Meeting

    Rheumatoid Factor Status Affects the Efficacy of First Biological Treatment in RA

    Yoshikazu Ogawa1, Nobunori Takahashi2, Koji Funahashi2, Shuji Asai3, Toki Takemoto3, Tatsuo Watanabe3, Nobuyuki Asai2, Naoki Ishiguro4 and Toshihisa Kojima2, 1orthopedic surgery, Nagoya University Hospital, Nagoya, Japan, 2Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya, Japan, 3Nagoya University Hospital, Nagoya, Japan, 4Department of Orthopedic Suregery, Nagoya University Hospital, Nagoya, Japan

    Background/Purpose: Rheumatoid factor (RF) is considered an important factor in diagnosing rheumatoid arthritis (RA). The association between the treatment efficacy of biological agents and RF…
  • Abstract Number: 1740 • 2015 ACR/ARHP Annual Meeting

    Anti-Cyclic Citrullinated Peptide Antibodies and Inflammatory Bowel Disease 

    Jaita Mukherjee1, Maria Mouyis1, Kavina Shah1, Mohammad Mahdi Saeidinejad1, Ayesha Akbar2 and Shahir Hamdulay1, 1Rheumatology, Northwick Park Hospital, Middlesex, United Kingdom, 2Gastroenterology, Northwick Park Hospital, Middlesex, United Kingdom

    Background/Purpose: Enteropathic arthropathy refers to the pattern of inflammatory arthritis seen in association with gastrointestinal pathology. Arthritis in the presence of inflammatory bowel disease can…
  • Abstract Number: 2257 • 2015 ACR/ARHP Annual Meeting

    Decline of Lung Function Is Associated with the Presence of Rheumatoid Factor in Korean Health Screening Subjects without Clinically Apparent Lung Diseases

    Jiwon Hwang1, Jae-Uk Song2, Hyungjin Kim3, Hyemin Jeong4, Yeong Hee Eun5, Chan Hong Jeon6, Ji-Min Oh7, Jaejoon Lee4, Hoon-Suk Cha8, Eun-Mi Koh5 and Joong Kyong Ahn9, 1Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea, 2Department of Internal Medicine, Kangbuk Samsung Hospital, Seoul, South Korea, 3Department of medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 4Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 5Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 6Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, South Korea, 7Anyang SAM Hospital, Anyang, South Korea, 8Division of Rheumatology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 9Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea

    Background/Purpose: Rheumatoid factor (RF) is an autoantibody directed against the Fc component of IgG. It is present in approximately 70-80% of rheumatoid arthritis (RA) patients…
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