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Abstracts tagged "rheumatoid arthritis"

  • Abstract Number: 1319 • ACR Convergence 2025

    The Association of Rheumatoid Arthritis in Patients with Vitiligo: Systematic Review and Meta-Analysis

    Nattanicha Chaisrimaneepan1, thunyaporn Khoruamklang2, Pitchaporn Yingchoncharoen3, Tulaton Sodsri4 and Miriam Paz3, 1Texas Tech University Health Sciences Center, Lubbock, TX, 22Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, bangkok, Thailand, 3Texas Tech University Health Sciences Center, Lubbock, 4Department of Medicine, Texas Tech University Health Sciences Center, Bangkok, Thailand

    Background/Purpose: Vitiligo is associated with many autoimmune diseases, but its association with rheumatic disease has not been well-defined. Therefore, we conducted a systematic review and…
  • Abstract Number: 1266 • ACR Convergence 2025

    Shared Decision Making in Rheumatoid Arthritis: Is RA disease activity associated with patient reported measures of shared decision making pre-SDM intervention?

    Jennifer Barton1, Joshua Baker2, gabriela Schmajuk3, Madhavi Valiveti4, Alexandra Bennett5, Benjamin Morasco6, Allison O'Neill7 and Meike Niederhausen8, 1VA Portland Health Care System/OHSU, Portland, OR, 2University of Pennsylvania, Philadelphia, PA, 3University of California, San Francisco, and San Francisco Veterans Affairs Medical Center, San Francisco, CA, 4VAMC Wilmington, Wilmington, DE, 5Center to Improve Veteran Involvement in Care (CIVIC) and VA Portland Health Care System, Portland, OR, 6Center to Improve Veteran Involvement in Care, VA Portland Health Care System, Portland, OR, 7Center to Improve Veteran Involvement in Care, VA Portland Health Care System, Portland, OR, 8Oregon Health & Science University/VA Portland Health Care System, Portland, OR

    Background/Purpose: Shared decision making (SDM) is outlined as the first overarching principle of the treat to target guidelines for rheumatoid arthritis (RA). The quality of…
  • Abstract Number: 1095 • ACR Convergence 2025

    Tolerance of non-TNF α treatments in patient with an inflammatory rheumatic (IRD) and autoimmune demyelinating diseases: French retrospective cases series

    dellal azeddine1, Jean-Guillaume Letarouilly2, Jacques Morel3, René-Marc Flipo4, Valerie Devauchelle5, richette pascal6, Philippe Dieude7, Hubert Marotte8, FELTEN Renaud9, LATOURTE Augustin10, CHEVET Baptiste11, HILLIQUIN Pascal12, SORDET Christelle9, DERNIS mmanuelle13, WENDLING Daniel14, Arsène Mekinian15, Nathalie BALLANDRAUD16, Christophe Richez17, TOURNADRE Anne18, salmon Jean -Hugues19, SAILLOT Carine20, kedra joanna21, nahon stephane22, LE GOFF Benoit23, Bruno Fautrel24, Francis BERENBAUM25, David SAADOUN26, PHAM Thao16 and SELLAM JEREMIE27, 1GHI LE RAINCY MONTFERMEIL, Montfermeil, France, 2Université de Lille, CHU Lille, Service de rhumatologie, Lille, France, LILLE, Nord-Pas-de-Calais, France, 3CHU and University of Montpellier, Montpellier, France, 4Université de Lille, CHU Lille, Service de rhumatologie, Lille, France, Lille, France, 5UBO, Brest, France, 6Rheumatology Department, Lariboisiere Hospital, Paris, Ile-de-France, France, 7Service de Rhumatologie, Hôpital Bichat APHP, Paris, Paris, Ile-de-France, France, 8INSERM 1059/University of Saint-Etienne, Saint-Etienne, France, 9Service de Rhumatologie, Centre de référence des maladies auto-immunes rares (RESO), Hôpitaux Universitaires de Strasbourg, Strasbourg, Strasbourg, Alsace, France, 10Rheumatology Department, Lariboisiere Hospital, Paris, France, 11CHU BREST, brest, Bretagne, France, 12CH SUD FRANCILIEN, PARIS, France, 13chu caen, CAEN, Haute-Normandie, France, 14CHU de Besançon, Besançon, Franche-Comte, France, 15Department of Internal Medicine, Inflammation-Immunopathology-Biotherapy Department (DMU i3), Saint-Antoine University Hospital, 75012 Paris, France, Paris, France, 16CHU MARSEILLE, marseille, Provence-Alpes-Cote d'Azur, France, 17Bordeaux University Hospital, Bordeaux, France, 18CHU CLERMONT, CLERMONT, Lorraine, France, 19CHU REIMS, REIMS, Champagne-Ardenne, France, 20CHU ORLEANS, ORLEANS, Pays de la Loire, France, 21Pitié-Salpêtrière Hospital, Rheumatology Department, APHP, Sorbonne University,, Paris, France, 22GHI LE RAINCY MONTFERMEIL, Montfermeil, Ile-de-France, France, 23CHU Nantes, Nantes, France, 24Sorbonne Université - APHP, Department of Rheumatology, Hôpital Pitié-Salpêtrière, Inserm UMRS 1136-5, PARIS, France, Paris, France, 25Sorbonne University/Inserm/AP-HP/4Moving Biotech, Paris, France, 26CHU LA PITIE SALPETRIERE, PARIS, Ile-de-France, France, 27Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, F-75012 Paris, France, /Rheumatology Department, AP-HP Saint-Antoine Hospital, 184, rue du Faubourg Saint-Antoine, 75012, Paris, France., Paris, France

    Background/Purpose: The use of TNFα antagonist is not recommended if the patient have a suspicion or demyelinating diseases (DD) confirmed [1]. There are a few…
  • Abstract Number: 1025 • ACR Convergence 2025

    Association Between Rural-Urban Clinics and the Management of Adult Rheumatoid Arthritis in the United States

    Megan Lorenz, Paxten Wahlund, Henry Elsenpeter, Abe Sahmoun and James Beal, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND

    Background/Purpose: Disease modifying anti-rheumatic drugs (DMARDs) improve symptom management and outcomes in rheumatoid arthritis (RA). While residence may influence management strategies and access to care,…
  • Abstract Number: 0924 • ACR Convergence 2025

    Human Serum Albumin Co-Modified with Malondialdehyde-Acetaldehyde and Citrulline Bind Multiple Scavenger Receptors and Alter Cellular Morphology

    Lauren Klingemann1, Michael Duryee1, Nozima Aripova1, Wenxian Zhou2, Hannah Johnson1, Breanna Butler1, Carlos Hunter1, Ted Mikuls1 and Geoffrey Thiele1, 1University of Nebraska Medical Center, Omaha, NE, 2University of Nebraska Medical Center, Bellevue, NE

    Background/Purpose: Post-translational modifications (PTMs) of self-proteins are implicated in the pathogenesis of rheumatoid arthritis (RA). The PTMs, malondialdehyde-acetaldehyde (MAA), citrulline (CIT), and the co-modification of…
  • Abstract Number: 0833 • ACR Convergence 2025

    Sputum Anti-CCP-IgA and NET-Associated Proteins Predict Risk and Timing of the Transition From Systemic Autoimmunity to Classified RA

    Timothy Wilson1, Claudia Lugo2, Marie Feser3, Mark Gillespie4, Troy Torgerson5, Gary Firestein6, V. Michael Holers7, Kevin Deane8 and Kristen Demoruelle9, 1Thomas Jefferson University, Philadelphia, PA, 2University of Colorado, Denver, CO, 3University of Colorado Anschutz Medical Campus, Aurora, CO, 4Allen Institute for Immunology, Seattle, WA, 5Allen Institute for Immunology, Enumclaw, WA, 6University of California, San Diego, San Diego, CA, 7University of Colorado Anschutz Medical Campus, Aurora, 8University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 9University of Colorado Anschutz Medical Campus, Golden, CO

    Background/Purpose: The presence of serum anti-CCP-IgG antibodies can predict the future development of clinically evident RA. Neutrophil extracellular trap (NET) formation can be a source…
  • Abstract Number: 0767 • ACR Convergence 2025

    Quality of Life in Patients with Rheumatoid Arthritis with Foot and Ankle Involvement

    Egla Samantha Sanchez-Peralta1, Andrea Cantero-Castro2, Karina Deciderio-Pavon3, Jesús Gilberto Espinoza-Gámez3, Irasema Arcibar-Liceaga3, Carolina De Leon-Carrillo3, Angel Kevin Garza-Elizondo1, Ryan Jared Sanchez-De la Cruz3, Jesus Alberto Cardenas-de la Garza4, Dionicio A. Galarza-Delgado5, Diana E. Flores-Alvarado1 and Jorge Alberto Elizondo-Rodriguez2, 1Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Nuevo Leon, Mexico, 2Traumatology Service, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo Leon, Mexico, 3Rheumatology Service, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo Leon, Mexico, 4Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Mexico, 5Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico

    Background/Purpose: Foot and ankle involvement in patients with rheumatoid arthritis is a common yet often underexplored and underrecognized manifestation. This can negatively affect patients' quality…
  • Abstract Number: 0489 • ACR Convergence 2025

    Efficacy and safety profile of JAK inhibitors in current practice in rheumatoid arthritis

    Omar Al Tabaa1, Salomé Abdellaoui1, Sophie Hecquet1, Marion Thomas2, Sandrine Carves1, Alice Combier1, Olivier Fogel3, Yannick Allanore4 and Jérôme Avouac5, 1Rheumatology department, Cochin Hospital, Paris, France, 2APHP, Paris, France, 3AP-HP, Paris, France, 4Université Paris Cité, Paris, France, 5Hôpital Cochin, AP-HP Centre - Université Paris Cité, Paris, France

    Background/Purpose: JAKi have been used in rheumatoid arthritis in current practice for several years now, with the progressive arrival on the market of 4 molecules.…
  • Abstract Number: 0473 • ACR Convergence 2025

    A Phase 2b Dose-Ranging Study of Peresolimab for Adults with RA

    Jay Tuttle1, Kirstin Griffing2, Mark Genovese2, Hyungmin Rha2, So Young Park2, Pia Yachi1, Ajay Nirula1, LANCE PFEIFER2, Tami Jo Rayle2, Jesus Abraham Simón-Campos3, Clifton Bingham4, Kevin Winthrop5, Daniel Aletaha6, Iain McInnes7, Yu Xue8, Yoshiya Tanaka9, Roy Fleischmann10, Paul Emery11 and Michael Weinblatt12, 1Lilly Biotechnology Center, San Diego, CA, 2Eli Lilly and Company, Indianapolis, IN, 3Köhler & Milstein Research, UADY School of Medicine, Merida, Yucatan, Mexico, 4Johns Hopkins University, Baltimore, MD, 5Oregon Health & Science University, Portland, OR, 6Medical University Vienna, Wien, Austria, 7University of Glasgow, Glasgow, United Kingdom, 8Huashan Hospital, Fudan University, Shanghai, China (People's Republic), 9University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 10Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX, 11University of Leeds, Leeds, England, United Kingdom, 12Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Peresolimab, a humanized IgG1 mAb, activates programmed cell death protein 1. In a phase 2a study, peresolimab demonstrated efficacy in participants (pts) with RA…
  • Abstract Number: 0457 • ACR Convergence 2025

    Pulmonary Profiles: Characterizing Lung Findings in Rheumatoid Arthritis Patients Undergoing Lung Cancer Screening

    Pratyusha Banik1, Melody Andrews1, Sudhakar Pipavath1 and Namrata Singh2, 1University of Washington, Seattle, WA, 2University of Washington, Bellevue, WA

    Background/Purpose: Rheumatoid arthritis (RA) has been associated with an increased risk of lung cancer with shared risk factors being heavy smoking history and possibly interstitial…
  • Abstract Number: 0439 • ACR Convergence 2025

    Osteoarthritis and Other Degenerative Musculoskeletal Disorders Are Common and Often Associated with Active Inflammation in Difficult-to-Treat Rheumatoid Arthritis: A Cross-Sectional Cohort

    Blanche QUERE1, Grégoire CORMIER2, LE GOFF Benoit3 and Adrien LE PLUART4, 1CHU de Nantes, Nantes, Pays de la Loire, France, 2Centre Hospitalier département de Vendée, La Roche Sur Yon, France, 3CHU Nantes, Nantes, France, 4CHU Nantes, Nantes, Pays de la Loire, France

    Background/Purpose: Despite advances in therapeutic strategies, a subset of patients with rheumatoid arthritis (RA) continues to experience persistent symptoms. In 2022, the EULAR proposed a…
  • Abstract Number: 0353 • ACR Convergence 2025

    Incidence of Clinical Fragility Fractures and Mortality in Patients with Rheumatoid Arthritis Treated with Rituximab

    Montserrat Roig Kim1, Carla Marco-Pascual2, Martí Aguilar-Coll1, Javier Narváez3, Joan Miquel Nolla1 and Carmen Gomez Vaquero4, 1Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain, 2Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, 3Hospital Universitario de Bellvitge, Barcelona, Spain, 4Hospital Universitari de Bellvitge, 08907 L'Hospitalet, Spain

    Background/Purpose: Patients with Rheumatoid Arthritis (RA) have an increased risk of osteoporosis and fragility fractures. Bone loss in RA is multifactorial and mainly determined by…
  • Abstract Number: 0187 • ACR Convergence 2025

    Message Testing in Online Recruitment Advertisements for a National Rheumatoid and Psoriatic Arthritis Study

    Matthew Kearney1, Sarah Hopkins Gillespie1, Stephanie Chen1, Tyler Cavin2, Christine Lindsay3, Christopher Ritchlin4, Jennifer Seifert5, Susan Goodman6, Jessica Fishman1 and Alexis Ogdie7, 1University of Pennsylvania, Philadelphia, PA, 2University of Rochester, Rochester, NY, 3Self, prosper, TX, 4University of Rochester Medical Center, Canandaigua, NY, 5University of Colorado and Oklahoma Medical Research Foundation, Aurora, CO, 6Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 7Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Wilmington, DE

    Background/Purpose: Study recruitment procedures have increasingly included paid advertisements using social media. However, it is unclear which types of message framing will be the most…
  • Abstract Number: 0095 • ACR Convergence 2025

    Effect of JAK Inhibitors on Osteoblast Differentiation

    Toshihiro Tanioka1 and Takeo Isozaki2, 1Graduate School of Pharmacy, Showa Medical University, Shinagawa-ku,Tokyo, Tokyo, Japan, 2Graduate School of Pharmacy, Showa Medical University, Tokyo, Tokyo, Japan

    Background/Purpose: Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and joint destruction. Among the therapeutic strategies available, Janus kinase (JAK) inhibitors have…
  • Abstract Number: 0075 • ACR Convergence 2025

    Impact of CXCL2 and IL-11 from Rheumatoid Arthritis Synovial Fibroblasts on Angiogenesis and Endothelial Cell Network Formation

    Elena Neumann1, Frederik Loetfering2, Paula Welbrink3, Corinna Heck3, Daria Kuersammer3, Klaus Frommer1, Stefan Rehart4 and Ulf Müller-Ladner1, 1Dept. of Rheumatology and Clinical Immunology, Campus Kerckhoff, Bad Nauheim, Justus-Liebig-University, Germany, Bad Nauheim, Hessen, Germany, 2Justus Liebig University Giessen, Campus Kerckhoff, Bad Nauheim, 3Justus-Liebig-Universität Gießen, Campus Kerckhoff, Bad Nauheim, Germany, 4Agaplesion Markus Hospital, Frankfurt, Hessen, Germany

    Background/Purpose: In rheumatoid arthritis (RA), hypervascularization contributes to synovial inflammation. RA synovial fibroblasts (RASF) contribute to cartilage and bone erosion but also promote angiogenesis. Activated…
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