ACR Meeting Abstracts

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Abstracts tagged "rheumatoid arthritis"

  • Abstract Number: 0473 • ACR Convergence 2023

    The Number of Rheumatoid Arthritis Patients Who Give up Pregnancy Due to the Disease Is Decreasing

    Ryo Inoue1, Sakiko Isojima1, Toshihiro Matsui2, Shigeto Tohma3 and Nobuyuki Yajima4, 1Division of Rheumatology, Department of Medicine, Showa University School of Medicine, Shinagawa City, Tokyo, Japan, 2NHO Sagamihara National Hospital, Kanagawa, Japan, 3NHO Tokyo National Hospital, Dallas, TX, 4Showa-Universtiy of Medicine, Tokyo, Japan

    Background/Purpose: Biologics have been shown not to be a disruption in pregnancy, and the reproductive health care environment surrounding rheumatoid arthritis patients has improved significantly.…
  • Abstract Number: 0769 • ACR Convergence 2023

    Development and Validation of a Combined Clinical and Genetic Risk Score for Interstitial Lung Disease in a Large, Multicenter, Prospective Rheumatoid Arthritis Cohort

    Austin Wheeler1, Joshua Baker2, Yangyuna Yang1, Punyasha Roul1, K Wysham3, Grant Cannon4, Gary Kunkel5, Gail Kerr6, Dana Ascherman7, Paul Monach8, Andreas Reimold9, Jill Poole1, Tony Merriman10, Ted R Mikuls11 and Bryant England1, 1University of Nebraska Medical Center, Omaha, NE, 2University of Pennsylvania, Philadelphia, PA, 3VA Puget Sound/University of Washington, Seattle, WA, 4University of Utah and Salt Lake City VA, Salt Lake City, UT, 5University of Utah, Salt Lake City, UT, 6Washington DC VAMC/Georgetown and Howard Universities, Washington, DC, 7University of Pittsburgh, Pittsburgh, PA, 8VA Boston Healthcare System, Boston, MA, 9University of Texas Southwestern Medical Center, Dallas, TX, 10University of Alabama at Birmingham, Birmingham, AL, 11Division of Rheumatology and Immunology, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is an extra-articular manifestation of RA that causes substantial morbidity and mortality. Although some clinical and genetic risk…
  • Abstract Number: 0808 • ACR Convergence 2023

    Real-World Disease Monitoring Patterns in Rheumatoid Arthritis-Associated Interstitial Lung Disease in the Veterans Affairs Health Care System

    Bryant England1, Tate Johnson1, Yangyuna Yang1, Punyasha Roul1, Daniel Hershberger1, Brian Sauer2, Grant Cannon3, Joshua Baker4 and Ted R Mikuls5, 1University of Nebraska Medical Center, Omaha, NE, 2Salt Lake City VA/University of Utah, Salt Lake City, UT, 3University of Utah and Salt Lake City VA, Salt Lake City, UT, 4University of Pennsylvania, Philadelphia, PA, 5Division of Rheumatology and Immunology, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: There are currently no clinical practice guidelines for monitoring RA-associated interstitial lung disease (RA-ILD). Pulmonary function tests (PFTs) and chest computed tomography (CT) imaging…
  • Abstract Number: 0976 • ACR Convergence 2023

    Sarcopenia and All-Cause Mortality in US Adults with and Without Rheumatoid Arthritis

    Qiping Xu and Xuanling Du, Mayo Clinic Health System, Mankato, MN

    Background/Purpose: Sarcopenia, which refers to the loss of muscle strength and mass, has been linked to adverse health outcomes. Although several systemic reviews have reported…
  • Abstract Number: 1022 • ACR Convergence 2023

    Lower Rates of Statin Therapy Initiation in Dermatomyositis/Polymyositis vs. Rheumatoid Arthritis Patients with Hyperlipidemia: A Multicenter USA-Based Study (2018-2023)

    Joseph Fares1, ross Summer1 and Giorgos Loizidis2, 1The Jane and Leonard Korman Respiratory Institute, Thomas Jefferson University Hospital, Philadelphia, PA, 2Division of Rheumatology, Thomas Jefferson University Hospital, Philadelphia, PA

    Background/Purpose: Despite the proven cardioprotective benefits of statin therapy in RA, concern for statin-associated muscle symptoms (SAMS) might deter clinicians from prescribing them to DM/PM…
  • Abstract Number: 1260 • ACR Convergence 2023

    Optimal Approaches for Reducing Depressive Symptoms in Rheumatoid Arthritis Patients Based on Psychological Interventions: A Systematic Review and Network Meta-analysis

    Zhang Lijuan and Wu Beiwen, Shanghai Jiao Tong University School of Medicine, Shanghai, China

    Background/Purpose: In recent years, numerous psychological interventions for rheumatoid arthritis (RA) patients have been developed. However, it remains unclear which psychological interventions are effective and…
  • Abstract Number: 1278 • ACR Convergence 2023

    Nature and Severity of Activity Limitations According to the Health Assessment Questionnaire Disability Index in Patients with Rheumatoid Arthritis and Functional Disability

    Manja van Wissen1, Maaike gademan1, Cornelia van den Ende2, Max Teuwen1, Wilfred Peter1, Dirkjan van Schaardenburg3, Alfons den Broeder2, Thea Vliet Vlieland4 and Salima van Weely1, 1Leiden University Medical Center, Leiden, Netherlands, 2Sint Maartenskliniek, Nijmegen, Netherlands, 3Reade, Amsterdam, Netherlands, 4Leids University Medical Center, Leiden, Netherlands

    Background/Purpose: Not withstanding modern treatment, some Rheumatoid Arthritis (RA) patients have severe disability due to persistently high disease activity, joint destruction/deformities and/or comorbidities. Insight into…
  • Abstract Number: 1294 • ACR Convergence 2023

    Patient Reported Outcome Measures for Rheumatoid Arthritis Disease Activity: Using Rasch Measurement Theory and Cognitive Interviewing to Achieve More Meaningful Measurement

    Tim Pickles1, Mike Horton2, Karl Bang Christensen3, Rhiannon Phillips4, David Gillespie1, Neil Mo5 and Ernest Choy6, 1Cardiff University, Cardiff, United Kingdom, 2University of Leeds, Leeds, United Kingdom, 3University of Copenhagen, Copenhagen, Denmark, 4Cardiff Metropolitan University, Cardiff, United Kingdom, 5Swansea Bay University Health Board, Port Talbot, United Kingdom, 6Section of Rheumatology, Cardiff University, Cardiff, United Kingdom

    Background/Purpose: Disease Activity (DA) monitoring is a standard of care in Rheumatoid Arthritis (RA). A systematic review of Patient Reported Outcome Measures (PROMs) for RA…
  • Abstract Number: 1310 • ACR Convergence 2023

    Comparison of Two Methotrexate Initiation Strategies in Rheumatoid Arthritis in Current Practice

    Paola Vidal-Montal1, Alice Combier2, Alexia STEELANDT2, Marion THOMAS2, Javier Narvaez3, Joan Miquel Nolla1, Yannick ALLANORE4 and Jerome AVOUAC5, 1Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 2HOPITAL COCHIN AP-HP, Service de Rhumatologie, Paris, France, 3Hospital Universitario de Bellvitge, Barcelona, Spain, 4Université Paris Cité, Paris, France, 5Rheumatology A Department, Hôpital Cochin, AP-HP Centre - Université Paris Cité, Paris, France

    Background/Purpose: To compare the efficacy and tolerance at 3 and 6 months of two methotrexate (MTX) initiation strategies in rheumatoid arthritis (RA). Methods: Retrospective,monocentric,cross-sectionalstudy including…
  • Abstract Number: 1327 • ACR Convergence 2023

    Effects of Long-Term Low Dose Glucocorticoid Treatment for Rheumatoid Arthritis on Body Weight and Blood Pressure: A Pooled Analysis of Individual Patient Data from Five Randomised Trials

    Andriko Palmowski1, Sabrina Mai Nielsen2, Zhivana Boyadzhieva3, Linda Hartman4, Judith Oldenkott5, Björn Svensson6, Ingiäld Hafström7, Siegfried Wassenberg8, Ernest Choy9, John Kirwan10, Robin Christensen11, Maarten Boers12 and Frank Buttgereit13, 1Charité - Universitätsmedizin Berlin, Berlin, Germany, 2The Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, 3Charité Universitatsmedizine - Berlin, Berlin, Germany, 4Amsterdam University Medical Centers, Amsterdam, Netherlands, 5Charite - University Medicine Berlin, Berlin, Germany, 6Lund University, Lund, Sweden, 7Karolinska Institutet, Stockholm, Sweden, 8Rheumazentrum Ratingen, Ratingen, Germany, 9Section of Rheumatology, Cardiff University, Cardiff, United Kingdom, 10University of Bristol, Bristol, United Kingdom, 11Musculoskeletal Statistics Unit, The Parker Institute, Copenhagen, Denmark, 12Amsterdam UMC, Vrije Universiteit, Amersfoort, Netherlands, 13Charité Universitätsmedizin, Dept. Rheumatology, Berlin, Germany

    Background/Purpose: High-dose glucocorticoids (GCs) can cause weight gain and hypertension. It is unclear whether GCs at ≤7.5mg/day prednisone equivalent ("low dose"), administered for rheumatoid arthritis…
  • Abstract Number: 1343 • ACR Convergence 2023

    Cardiovascular (CV) and Malignancy Events in the Filgotinib Rheumatoid Arthritis (RA) Clinical Development Program up to 8.3 Years

    Xavier Mariette1, Sven Borchmann2, Sandrine Aspeslagh3, Jaime Calvo- Alén4, Richard Moriggl5, Zoltan Szekanecz6, Francesco De Leonardis7, Nadia Verbruggen8, Paul Van Hoek9, Marc Schmalzing10, Andreas Stallmach11, Christina Charles-Schoeman12, Vijay Rajendran13, Christine Rudolph9, Chris Watson14, Yoshiya Tanaka15 and Ernest Choy16, 1Université Paris-Saclay, Le Kremlin-Bicêtre, France, 2Department of Internal Medicine, University of Cologne, Cologne, Germany, 3Department of Medical Oncology, UZ Brussel, Brussels, Belgium, 4Rheumatology, Bioaraba Research Unit, Hospital Universitario Araba, Vitoria, Spain, 5Institute of Animal Breeding and Genetics, University of Veterinary Medicine, Vienna, Austria, 6Division of Rheumatology, University of Debrecen, Debrecen, Hungary, 7Medical Affairs, Galapagos GmbH, Basel, Switzerland, 8Biostatistics, Galapagos NV, Mechelen, Belgium, 9Medical Safety, Galapagos NV, Mechelen, Belgium, 10University Hospital, Rheumatology/Clinical Immunology, Department of Internal Medicine II, Würzburg, Germany, 11Department of Internal Medicine, Jena University Hospital, Jena, Germany, 12UCLA Medical Center, Santa Monica, CA, 13Clinical Research, Galapagos NV, Mechelen, Belgium, 14Medical Affairs, Galapagos Biotech Ltd., Cambridge, United Kingdom, 15University of Occupational and Environmental Health, Kitakyushu, Japan, 16Section of Rheumatology, Cardiff University, Cardiff, United Kingdom

    Background/Purpose: Filgotinib (FIL) is a Janus kinase (JAK) 1 preferential inhibitor for the treatment of RA. Data from the ORAL Surveillance post-marketing study (NCT02092467) suggest…
  • Abstract Number: 1651 • ACR Convergence 2023

    Beneficial Effect of Temporary Methotrexate Interruption on B and T Cell Responses upon SARSCoV-2 Vaccination in Patients with Rheumatoid Arthritis or Psoriatic Arthritis

    Esther Vicente Rabaneda1, Pedro Martínez-Fleta2, Ana Triguero-Martínez2, Emilia Roy3, Miren Uriarte-Ecenarro4, Francisco Gutiérrez-Rodríguez4, Patricia Quiroga4, Ana Romero4, Nuria Montes2, Laura Esparcia Pinedo2, María Aranzazu Alfranca2, Rosario Garcia-Vicuna5, Francisco Sánchez-Madrid2, Isidoro González-Álvaro4 and Santos Castañeda5, 1Rheumatology, Hospital Universitario de La Princesa, Madrid, Spain, 2Division of Immunology, Hospital Universitario de La Princesa, Madrid, Spain, 3Division of Internal Medicine, Hospital Universitario de La Princesa, Madrid, Spain, 4Division of Rheumatology, Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Spain, 5Hospital Universitario de la Princesa, Madrid, Spain

    Background/Purpose: Previous published works have raised the concern that methotrexate (MTX) might have a negative effect on immune response upon vaccine administration. At the beginning…
  • Abstract Number: 1728 • ACR Convergence 2023

    A Novel Animal Model for Investigating the Effect of HLA-DRB1 on Atherosclerosis

    Garth Blackler, James Akingbasote, Patti Kiser, Christopher Howlett, Ewa Cairns and Lillian Barra, Western University, London, ON, Canada

    Background/Purpose: HLA-DRB1 alleles are associated with various autoimmune and inflammatory conditions, including rheumatoid arthritis, polymyalgia rheumatica, giant cell arteritis, systemic lupus erythematosus, diabetes and atherosclerotic…
  • Abstract Number: 1744 • ACR Convergence 2023

    Histological and Molecular Comparison in the Synovial Tissue of Patients with Active Rheumatoid Arthritis to Remission

    Selina Ohl1, Klaus Frommer1, Markus Rickert2, Stefan Rehart3, Ulf Müller-Ladner1 and Elena Neumann1, 1Justus Liebig University Gießen, Campus Kerckhoff, Bad Nauheim, Germany, 2Dept. of Orthopaedics and Orthopaedic Surgery, University Hospital Giessen and Marburg, Giessen, Germany, 3Dept. of Orthopaedics and Trauma Surgery, Agaplesion Markus Hospital Frankfurt, Frankfurt, Germany

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease which leads to local and systemic manifestations. Subsequently, the inflamed synovium drives the destruction of…
  • Abstract Number: 1760 • ACR Convergence 2023

    Methotrexate Augments the Release of Granulocyte-macrophage Colony-stimulating Factor from Activated Rheumatoid Arthritis Fibroblast-like Synoviocytes – Possible Consequences for Persistence of Joint Inflammation

    Beatrice Bergström1, Tilia Selldén1, Miriam Bollmann2, Mattias N.D Svensson1 and Anna-Karin Hultgård Ekwall3, 1University of Gothenburg, Gothenburg, Sweden, 2Department of Rheumatology and Inflammation research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 3University of Gothenburg, Kullavik, Sweden

    Background/Purpose: Activated fibroblast-like synoviocytes (FLS) are important mediators of synovitis and structural damage in rheumatoid arthritis (RA)[1]. Granulocyte-macrophage colony-stimulating factor (GM-CSF, encoded by the CSF2…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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