Abstracts tagged "Rheumatoid arthritis (RA)"

Abstract Number: 2684 • 2013 ACR/ARHP Annual Meeting
Impact Of Anti-Rheumatic Treatment On Immunogenicity Of Pandemic H1N1 Influenza Vaccine In Patients With Arthritis
Meliha C. Kapetanovic¹, Lars-Erik Kristensen², Tore Saxne³, Teodora Aktas⁴, Andreas Mörner⁴ and Pierre Geborek⁵, ¹Dept of Clinical Sciences Lund, Section of Rheumatology, Lund University, Lund, Sweden, ²Dept of Clinical Sciences, Lund, Section for Rheumatology, Lund University, Faculty of Medicine, Malmö, Sweden, ³Section of Rheumatology, Deparment of Clinical Sciences, Lund, Lund University, Lund, Sweden, ⁴Vaccinology Unit, Department of Diagnostics and Vaccinology, Swedish Institute for Communicable Disease Control, Solna, Sweden., Vaccinology Unit, Department of Diagnostics and Vaccinology, Swedish Institute for Communicable Disease Control, Solna, Sweden., Solna, Sweden, ⁵Section of Rheumatology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden
Impact of anti-rheumatic treatment on immunogenicity of pandemic H1N1 influenza vaccine in patients with arthritis Background/Purpose: An adjuvanted pandemic H1N1 influenza (pH1N1) vaccine (Pandemrix®) was…
Abstract Number: 2304 • 2013 ACR/ARHP Annual Meeting
Follow-Up Of Patients With Preclinical Rheumatoid Arthritis – Results Of a Telephone Survey
Pascal Klaus¹, Vivien Köhler¹, Hans Bastian¹, Tanja Braun¹, Eva Gremmelsbacher¹, Vera Höhne-Zimmer¹, Frank Buttgereit¹, Gerd Burmester¹ and Jacqueline Detert², ¹Charité - Universitätsmedizin Berlin, Berlin, Germany, ²Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Berlin, Germany
Background/Purpose: Preclinical rheumatoid arthritis (pre-RA) describes a subset of patients with arthralgia (but no synovitis) where either anti-citrullinated peptide antibodies (ACPA) and/or rheumatoid factor (RF)…
Abstract Number: 1371 • 2013 ACR/ARHP Annual Meeting
Tuberculosis Infection In Patients With Tumor Necrosis Factor–α Antagonists In South Korea;retrospective Analysis Using By National Health Insurance Review and Assessment Service
Jong Wook Beom¹, Eun-Jung Park², Jinseok Kim³, Se Chang Park⁴ and Gi Hyeon Seo⁵, ¹Medicine, Jeju National University Hospital, Jeju, South Korea, ²Internal Medicine, Department of Medicine, Jeju National University Hospital, Jeju University School of Medicine, Republic of Korea, Jeju, South Korea, ³Internal Medicine, Jeju National University Hospital, Jeju, South Korea, ⁴Veterinary Medicine, Seoul National University, Seoul, South Korea, ⁵Health Insurance Review and Assessment Service, Seoul, South Korea
Background/Purpose: Tumor necrosis factor-α (TNF-α) antagonists bring new hope for treating rheumatoid arthritis (RA) over the past decade. However, the subsequent increased risk of developing…
Abstract Number: 376 • 2013 ACR/ARHP Annual Meeting
The Risk Of Pneumococcal Infections After Immunisation With Pneumococcal Conjugate Vaccine Compared To Non-Vaccinated Inflammatory Arthritis Patients
Johanna Bengtsson¹, Pierre Geborek², Tore Saxne³, Martin Englund⁴, Ingemar F. Petersson⁴, Jan-Åke Nilsson⁵, Göran Jönsson⁶ and Meliha C. Kapetanovic⁷, ¹Department of Clinical Sciences, Lund, Section of Rheumatology, Lund University and Skåne University Hospital, Lund, Sweden, Lund, Sweden, ²Section of Rheumatology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden, ³Section of Rheumatology, Deparment of Clinical Sciences, Lund, Lund University, Lund, Sweden, ⁴Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ⁵Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, ⁶Lund Universoty, Dept of Clinical Sciences Lund, Section of Infectious Diseases, Lund, Sweden, ⁷Dept of Clinical Sciences Lund, Section of Rheumatology, Lund University, Lund, Sweden
The risk of pneumococcal infections after immunisation with pneumococcal conjugate vaccine compared to non-vaccinated inflammatory arthritis patientsBackground/Purpose: The purpose was to examine the risk of…
Abstract Number: 2686 • 2013 ACR/ARHP Annual Meeting
Impact of Methotrexate Dose Reduction Upon Initiation of Adalimumab On Clinical and Ultrasonographic Parameters in Patients With Moderate to Severe Rheumatoid Arthritis
Gurjit S. Kaeley¹, Amy M. Evangelisto², Midori Jane Nishio³, Shufang Liu⁴ and Hartmut Kupper⁵, ¹College of Medicine, University of Florida, Jacksonville, FL, ²Arthritis, Rheumatic and Back Disease Associates, Voorhees, NJ, ³Diablo Clinical Research, Walnut Creek, CA, ⁴AbbVie Inc., North Chicago, IL, ⁵AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany
Background/Purpose: Methotrexate (MTX) is the recommended first-line disease-modifying antirheumatic drug (DMARD) for the treatment of moderately to severely active rheumatoid arthritis (RA). Whether patients (pts)…
Abstract Number: 2242 • 2013 ACR/ARHP Annual Meeting
Patient Versus Physician Joint Counts In Rheumatoid Arthritis Utilizing a Unique Self-Joint Examination Tool
Daisy Bang¹, Yomei Shaw², Christine L. Amity³, Kelly A. Reckley⁴, Ilinca D. Metes⁵ and Marc C. Levesque⁶, ¹Division of General Internal Medicine, University of Pittsburgh, Pittsburgh, PA, ²Department of Health Policy and Management, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, ³Rheumatology & Clinical Immun, Univ of Pittsburgh, Pittsburgh, PA, ⁴Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, ⁵Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁶Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: The quantitative assessment of disease activity has been endorsed by the American College of Rheumatology (ACR) to improve rheumatoid arthritis (RA) outcomes. To facilitate…
Abstract Number: 1356 • 2013 ACR/ARHP Annual Meeting
Disease Activity Of Rheumatoid Arthritis Is Influenced By Seasonal Change, As Analyzed Based On a Nationwide Japanese Cohort Database
Tetsuji Sawada¹, Hiroaki Mori², Kota Shimada³, Haeru Hayashi¹, Koichiro Tahara¹, Jinju Nishino⁴ and Shigeto Tohma⁵, ¹Rheumatology, Tokyo Medical University, Tokyo, Japan, ²Rheumatology, Tokyo Meidical University, Tokyo, Japan, ³Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan, ⁴Nishino Clinic, Orthopedics and Rheumatology, Tokyo, Japan, ⁵Clinical Research Center for Allergy and Rheumatology, Sagamihara Hospital, National Hospital Organization, Sagamihara, Japan
Background/Purpose: Previous studies have suggested that environmental factors, such as weather, humidity and seasonal change, may affect rheumatoid arthritis (RA). In the present study, we…
Abstract Number: 357 • 2013 ACR/ARHP Annual Meeting
Predictive Value Of Anti Cyclic Citrullinated Peptide and Rheumatoid Factor To The Development Of Rheumatoid Arthritis In a Cohort Of Healthy Relatives Of Patients With Rheumatoid Arthritis
Jose Dionisio Castillo-Ortiz¹ and Cesar Ramos-Remus², ¹Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ²Unidad de Investigacion en Enfermedades Cronico-Degenerativas, Guadalajara, Mexico
Background/Purpose: Consanguineous relatives of patients with RA are at a higher risk to develop RA. It is also known that specific antibodies including CCP and…
Abstract Number: 2690 • 2013 ACR/ARHP Annual Meeting
Survival Of The Second Biologic After The First Tumor Necrosis Factor Alpha Inhibitor’s Failure In The Treatment Of Rheumatoid Arthritis: Prospective Observational Data From Biorx.Si Registry
ŽIga Rotar¹ and Matija Tomsic², ¹Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, ²Department of Rheumatology, University Medical Centre Ljubjana, Ljubljana, Slovenia
Background/Purpose: Current recommendations for management of RA propose a tumor necrosis factor alpha inhibitor (TNFi) for patients failing to achieve the treatment target with synthetic…
Abstract Number: 1951 • 2013 ACR/ARHP Annual Meeting
The Spring Ligament Window: A Unique Sonoanatomic View Into a Complex Rheumatoid Joint
Joanne Kitchen¹, I. Moller², Maribel Miguel-Perez³ and David A. Bong⁴, ¹Instituto Poal de Reumatolgia, Barcelona, Spain, ²Instituto Poal, Barcelona, Spain, ³University of Barcelona, Barcelona, Spain, ⁴Instituto Poal de Reumatologia, Barcelona, Spain
Background/Purpose: The calcaneonavicular or spring ligament (SL) is a group of 3 stout non-elastic fibrocartilaginous bands in the medial mid-foot that is important in maintaining…
Abstract Number: 1335 • 2013 ACR/ARHP Annual Meeting
Sarcopenia Is Associated With Joint Damage In Rheumatoid Arthritis patients a Cross Sectional Study In a Peruvian Population
Erika Noriega¹, Rocio V. Gamboa-Cardenas¹, Manuel F. Ugarte-Gil^2,3, Mariela Medina-Chinchon², Francisco Zevallos-Miranda², J. Mariano Cucho-Venegas², Risto A. Perich-Campos^2,4, Jose L. Alfaro-Lozano², Zoila Rodriguez-Bellido^2,4 and Cesar A. Pastor-Asurza^2,4, ¹Rheumatology, Hospital Almenara, Lima, Peru, ²Rheumatology, Hospital Guillermo Almenara, EsSalud, Lima, Peru, ³Universidad Cientifica del Sur, Lima, Peru, ⁴Universidad Nacional Mayor de San Marcos, Lima, Peru
Background/Purpose: Sarcopenia is a low-level, smoldering inflammatory state driven by cytokines and oxidative stress. In rheumatoid arthritis (RA) the relationship between sarcopenia and severity of…
Abstract Number: 224 • 2013 ACR/ARHP Annual Meeting
Ultrasound Evaluation Of Joints, Tendons and Subcutaneous Tissue Of Hands In 74 Scleroderma Patients
Anat Scheiman-Elazary¹, Ami Ben-Artzi², Suzanne Kafaja², V Ranganath³, Nabeel Borazan⁴, Philip J. Clements⁵ and Daniel Furst⁶, ¹Rheumatology, Rheumatology UCLA, Los Angeles, CA, ²David Geffen School of Medicine, UCLA, Los Angeles, CA, ³Medicine, Division of Rheumatology, David Geffen School of Medicine, UCLA, Los Angeles, CA, ⁴Medicine, Rheumatology UCLA, Los Angeles, CA, ⁵University of California, Los Angeles, Department of Medicine, Los Angeles, CA, ⁶Rheumatology, David Geffen School of Medicine, UCLA, Los Angeles, CA
Background/Purpose: A previous ultrasound study of the hands in scleroderma (SSC) and rheumatoid arthritis (RA), found mild inflammatory changes in the tendons and joints of…
Abstract Number: 2644 • 2013 ACR/ARHP Annual Meeting
Phase IB/Iia Study On Intravenous Administration Of Expanded Allogeneic Adipose-Derived Mesenchymal Stem Cells In Refractory Rheumatoid Arthritis Patients
JM Alvaro-Gracia¹, Juan A. Jover², Rosario Garcia-Vicuña³, Luis Carreño⁴, Alberto Alonso⁵, Sara Marsal⁶, Francisco J. Blanco⁷, Víctor M. Martínez-Taboada⁸, Peter C. Taylor⁹, Federico Díaz-González¹⁰ and Lydia Dorrego¹¹, ¹Unidad de Terapias Biológicas. Servicio de Reumatología, Hospital Universitario de La Princesa, Madrid, Spain, ²Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, ³Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, ⁴Rheumatology, Gregorio Marañón Hospital, Madrid, Spain, ⁵Hospital de Cruces, Bilbao, Spain, ⁶Rheumatology Research Group, Vall d'Hebron Hospital Research Institute, Barcelona, Spain, ⁷INIBIC-Hospital Universitario A Coruña. Rheumatology Division. Genomic Group, A Coruña, Spain, ⁸Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV., Santander, Spain, ⁹NDORMS, Botnar Research Centre, University of Oxford, Oxford, United Kingdom, ¹⁰Hospital Universitario de Canarias, La Laguna. Tenerife, Spain, ¹¹TiGenix, Tres Cantos, Spain
Background/Purpose: Expanded adipose-derived stem cells (eASCs) are shown to have immune-modulatory effects both in vitro and in animal models of arthritis. eASCs are currently under…
Abstract Number: 1952 • 2013 ACR/ARHP Annual Meeting
The Value Of An Automated Ultrasound System In The Detection Of Synovitis
Ruediger Mueller¹, Mathias Gruenke², Joerg Wendler³, Florian Schuch³, Karina Hofmann-Preiss⁴, Ina Boettger⁴, Ruediger Jakobs⁵, Hendrik Schulze-Koops⁶ and Johannes von Kempis¹, ¹Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, ²Division of Rheumatoloy, Medizinische Klinik IV, University of Munich, Munich, Germany, ³Schwerpunktpraxis Rheumatologie, Erlangen, Germany, ⁴Institut für bildgebende Diagnostik und Therapie, Erlangen, Germany, ⁵Siemens AG, Erlangen, Germany, ⁶Division of Rheumatology and Clinical Immunology, University of Munich, Munich, Germany
Background/Purpose: The detection of joint swelling caused by synovitis is important for the diagnosis and assessment of inflammatory arthritis. Ultrasound (US) and MRI have proven…
Abstract Number: 1291 • 2013 ACR/ARHP Annual Meeting
COVA322: Overcoming Limitations Of Current Biologics In Rheumatoid Arthritis By a Novel, Bispecific Tumor-Necrosis-Factor-Alpha / Interleukin-17A (TNF/IL-17A) Inhibitor Moving Towards The Clinic
Dragan Grabulovski, Michela Silacci, Nadja Baenziger-Tobler, Wibke Lembke, Wenjuan Zha, Richard Woods, Isabella Attinger-Toller, Roger Santimaria, Susann Koenig-Friedrich, Ulrike von der Bey, Mathias Locher and Julian Bertschinger, Covagen AG, Schlieren, Switzerland
Background/Purpose: Biologic treatment options such as TNF inhibitors have revolutionized the treatment of inflammatory diseases, such as rheumatoid arthritis (RA), psoriasis and psoriatic arthritis. However, there…

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