ACR Meeting Abstracts

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Abstracts tagged "Rheumatoid arthritis (RA)"

  • Abstract Number: 2390 • 2019 ACR/ARP Annual Meeting

    Prediction of Disease Relapses by Multi-biomarker Disease Activity Score and Autoantibody Status in RA Patients Tapering DMARD Treatment in Stable Remission

    Melanie Hagen1, Koray Tascilar 2, Michaela Reiser 3, Judith Haschka 4, Arnd Kleyer 5, Larissa Valor 6, Bernhard Manger 7, Georg Schett 8 and Jürgen Rech 9, 1Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen Nürnberg (FAU), University Hospital Erlangen, Erlangen, Germany, Erlangen, Germany, 2Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany, Erlangen, Bayern, Germany, 3Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Bayern, Germany, 4Karl Landsteiner Institute for Gastroenterology and Rheumatology, St. Vincent Hospital Vienna, II Medical Department, Vienna, Austria, 5Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany, Erlangen, Germany, 6Friedrich-Alexander-University Erlangen-Nürnberg. Department of Internal Medicine 3 - Rheumatology and Immunology. Erlangen., Erlangen, Germany, 7Friedrich-Alexander-University Erlangen-Nürnberg. Department of Internal Medicine 3 - Rheumatology and Immunology. Erlangen. Germany., Erlangen, Germany, 8Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany, 9Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany

    Background/Purpose: Achieving remission is the ultimate treatment goal in patients with rheumatoid arthritis (RA). With the development and wider use of highly effective disease modifying…
  • Abstract Number: 2772 • 2019 ACR/ARP Annual Meeting

    Clinical and Biological Changes in Rheumatoid Arthritis Patients Exposed to an Anti-inflammatory Diet

    francesca cedola1, Roxana Coras 2, Marta Fernandez-Bustamante 3, Meritxell Agusti-Perez 3, Maram Al-Harthi 3, Susan Lee 3, Abha Singh 3, Choi Soo 3, Kathy Nguyen 3, Oswald Quehenberger 3, Tatyana Shekhtman 3, Shahrokh Golshan 3 and Monica Guma 4, 1University of California San Diego, Rome, Italy, 2. Department of Medicine, School of Medicine. University of California, San Diego, 3University of California San Diego, san diego, 4Department of Medicine, School of Medicine. University of California San Diego, La Jolla, United States

    Background/Purpose: RA patients often inquire about dietary interventions to improve disease control, as they perceive quick changes in pain and/or swelling after consumption of certain…
  • Abstract Number: 2872 • 2019 ACR/ARP Annual Meeting

    Risk of 30-day Readmission and Adverse Events After Primary Hip or Knee Arthroplasty: A Comparison of Patients with Rheumatoid Arthritis versus Osteoarthritis Using the Nationwide Readmission Database

    Ali Yazdanyar1, Anthony Donato 2, Kathleen McElwee 3, Mary Chester Wasko 4 and Michael Ward 5, 1Lehigh Valley Hospital- Cedar Crest, Allentown, PA, 2Reading Hospital, PA, Reading, 3Reading Hospital, Reading, PA, 4Allegheny Health Network-West Penn Hospital, Pittsburgh, PA, 5NIAMS, Bethesda, MD

    Background/Purpose: To assess the risk of 30-day readmission, mortality, and adverse events among adults with Rheumatoid Arthritis as compared to Osteoarthritis after primary hip or…
  • Abstract Number: 36 • 2019 ACR/ARP Annual Meeting

    Discovery, Verification and Validation of Rheumatoid Arthritis Activity Monitoring Biomarkers

    Lucía González-Rodríguez1, Valentina Calamia 1, Rocío Paz-González 1, Patricia Fernández-Puente 1, Cristina Ruiz-Romero 1, Antonio Julià 2, Antonio Fernández-Nebro 3, Jesús Tornero 4, Sara Marsal 5 and Francisco J. Blanco 6, 1Proteomics Group, Rheumatology Division, ProteoRed, PRB2-ISCIII. INIBIC-Hospital Universitario A Coruña,15006 A Coruña-Spain, A Coruña, Galicia, Spain, 2Rheumatology Research Group, Vall d’Hebron Hospital Research Institute, Barcelona, Spain., Barcelona, Catalonia, Spain, 3UGC Reumatología, Instituto de Investigación Biomédica (IBIMA), Hospital Regional Universitario de Málaga, Spain., Málaga, Andalucia, Spain, 4Hospital Universitario Guadalajara, Guadalajara, Spain., Guadalajara, Castilla-La Mancha, Spain, 5Vall d’Hebron Hospital, Barcelona, Catalonia, Spain, 6Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain

    Background/Purpose: Rheumatoid arthritis (RA) is a long-lasting inflammatory autoimmune disorder that ultimately leads to the destruction of joint architecture. The activity of this disease is…
  • Abstract Number: 117 • 2019 ACR/ARP Annual Meeting

    The Indole Derivative NecroX Blocks Th17 Cell Differentiation and Fibroblast-like Synoviocytes-mediated Th1/Th17 Responses in Rheumatoid Arthritis

    Hyun Jung Yoo1, Shin Eui Kang 2, Ji Hye Lee 3, Ra Ham Kim 4 and Yeong-Wook Song 5, 1Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Medicine, Seoul National University, Seoul, Repulbic of Korea, Seoul, Republic of Korea, 2Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Medicine, Seoul National University, Seoul, Republic of Korea, Seoul, Republic of Korea, 3Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea., Seoul, Republic of Korea, 4Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Medicine, Seoul National University, Seoul, Republic of Korea, Seoul, Republic of Korea, 5Seoul National University Hospital, Seoul, Republic of Korea

    Background/Purpose: Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of synovium, which causes progressive joint destruction and reduction in quality of life.…
  • Abstract Number: 196 • 2019 ACR/ARP Annual Meeting

    Risk of Subsequent Atherosclerotic Cardiovascular Disease After the First Unprovoked Venous Thromboembolism in Patients with Rheumatoid Arthritis

    Gulsen Ozen1, Sofia Pedro 2, Rebecca Schumacher 2, Teresa Simon 3 and Kaleb Michaud 1, 1University of Nebraska Medical Center, Omaha, NE, 2Forward, The National Databank for Rheumatic Diseases, Wichita, KS, 3Bristol-Myers Squibb*, Princeton, NJ

    Background/Purpose: With the advent of JAK inhibitors has come increased concerns for the risk of venous thromboembolism (VTE), which was already known to be increased…
  • Abstract Number: 315 • 2019 ACR/ARP Annual Meeting

    Improving the Rate of Tuberculosis Screening Among High Risk Rheumatoid Arthritis Patients on Biologic Agents Using a Proposed Questionnaire

    Hamayon Babary1, Suraiya Afroz 1, John Carter 1, Yih Lin 1, Marie O'Brien 2, Marcos Maldonado 1, Helen Bateman 1, Gabriela Montes-Rivera 1, Grace Berlin 2, Dan Tseytlin 2, Madeline MacDonald 3, Yasmin Ayoubi 4, Matthew Nguyen 4, Shalini Setty 4, Rahul Mhaskar 4 and Joanne Valeriano-Marcet 1, 1University of South Florida Division of Rheumatology, Tampa, FL, 2Lehigh Valley Health Network, Allentown, PA, 3University of South Florida, College of Medicine, Tampa, FL, 4University of South Florida College of Medicine, Tampa, FL

    Background/Purpose: The use of biologics has transformed the treatment paradigm for RA; however, reactivation of Mycobacterium Tuberculosis is still a concern. Frequent TB screenings without…
  • Abstract Number: 454 • 2019 ACR/ARP Annual Meeting

    Principal Component Analysis Identifies Unique Sub-Populations in Rheumatoid Arthritis Using a Combination of Serological Biomarkers: A Cross Sectional Study

    Jordan Van Dyk1, Bryan Heard 1 and Cheryl Barnabe 1, 1University of Calgary, Calgary, AB, Canada

    Background/Purpose: Determining the prognosis of rheumatoid arthritis (RA) could guide more precise treatment selection, optimizing outcomes while minimizing unnecessary therapeutic exposures. It is important that…
  • Abstract Number: 488 • 2019 ACR/ARP Annual Meeting

    Citrullinated Antigens with Multiple Citruline Similar Motif Could Be Used for RA Diagnosis

    zhiwei ru 1, Xuedong Chen 2, Xiaoyan huang 1, Jianrong Lou 1, YongZheng peng 3 and Xiang Yang1, 1Leide bioscience Inc, guang zhou, Guangdong, China (People's Republic), 2Southern Medicine University, guang zhou, Guangdong, China (People's Republic), 3Southern Medicine University, guang dong, Guangdong, China (People's Republic)

    Background/Purpose: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic joint inflammation that ultimately leads to joint destruction. Diagnosis of RA is important…
  • Abstract Number: 535 • 2019 ACR/ARP Annual Meeting

    Exploratory Analysis of a Phase 2b Study Confirms Substantial Pain Improvement with Anti-GM-CSF Monoclonal Antibody Otilimab (GSK3196165) in Patients (Pts) with Active RA

    Christopher D. Buckley1, Jesus A. Simon Campos 2, Vyacheslav Zhdan 3, Brandon Becker 4, Olivier Collignon 5, Carol Hawkes 6, Mark Layton 7, Jatin Patel 8, Katherine Davy 7, Anubha Gupta 7 and Sofia Fernandes 5, 1Rheumatology Research Group, University of Birmingham, Birmingham, United Kingdom, 2Köhler & Milstein Research, Mérida, Mexico, 3M.V. Sklifosovskyi Poltava Regional Clinical Hospital, Poltava, Ukraine, 4GSK, Upper Providence, PA, 5GSK, Stevenage, United Kingdom, 6GSK, Stockley Park, United Kingdom, 7GlaxoSmithKline, Stevenage, United Kingdom, 8GlaxoSmithKline, Stockley Park, United Kingdom

    Background/Purpose: Treatment of pain remains a priority for patients (pts) with RA. Otilimab (GSK3196165) is a human mAb that inhibits GM-CSF, a key driver in…
  • Abstract Number: 840 • 2019 ACR/ARP Annual Meeting

    Trajectory of Multimorbidity in Rheumatoid Arthritis in a U.S. Commercial Insurance Claims Database from 2006-2015

    Bryant England1, Punyasha Roul 2, Fang Yu 2, Harlan Sayles 2, Kaleb Michaud 2, Fenglong Xie 3, Jeffrey Curtis 4 and Ted Mikuls 5, 1VA Nebraska-Western IA Health Care System & University of Nebraska Medical Center, Omaha, 2University of Nebraska Medical Center, Omaha, NE, 3University of Alabama at Birmingham, Birmingham, 4University of Alabama at Birmingham, Birmingham, AL, 5VA Nebraska-Western IA Health Care System & University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Multimorbidity, the presence of multiple chronic conditions, predisposes individuals to disability and premature mortality. RA is well known to be associated with select chronic…
  • Abstract Number: 956 • 2019 ACR/ARP Annual Meeting

    The Impact of Psychiatric Comorbidity on Health Care Utilization and Preventive Health Care in Rheumatoid Arthritis: A Population Based Study

    Carol Hitchon1, Charles Bernstein 1, James Bolton 1, Renée El-Gabalawy 1, John Fisk 2, Alan Katz 1, Lisa Lix 3, James Marriott 1, Scott Patten 4, Christine Peschken 3, Jitender Sareen 1, Alexander Singer 1, Randy Walld 1 and Ruth Ann Marrie 1, 1University of Manitoba, Winnipeg, MB, Canada, 2Dalhousie University, Halifax, NS, Canada, 3University of Manitoba, Winnipeg, Canada, 4University of Calgary, Calgary, AB, Canada

    Background/Purpose: Psychiatric comorbidity is increased in rheumatoid arthritis (RA) and may complicate medical care, increasing the risk of adverse health outcomes and health care utilization…
  • Abstract Number: 1170 • 2019 ACR/ARP Annual Meeting

    Cortical Bone Erosion in the 2nd Metacarpal Bone Head: Association with Its Bone Mineral Density by HR-pQCT in Rheumatoid Arthritis Patients

    Camille Figueiredo1, Mariana Perez 1, Ana Cristina de Medeiros Ribeiro 2, Valeria Caparbo 1 and Rosa Pereira 3, 1Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil, 2Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil, 3Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Sao Paulo, Brazil

    Background/Purpose: Periarticular trabecular bone loss and local cortical bone erosions are typical features of bone disease in rheumatoid arthritis (RA) 1 . Little, however, is…
  • Abstract Number: 1343 • 2019 ACR/ARP Annual Meeting

    Pop a Pill or Give Myself a Shot? Patient Perspectives of Disease-modifying Anti-rheumatic Drug (DMARD) Choice for Rheumatoid Arthritis (RA)

    Jasvinder Singh1, Haley Tornberg 2 and Susan Goodman 3, 1University of Alabama Medical Center, Birmingham, 2Hospital for Special Surgery, New York, NY, 3Hospital For Special Surgery/Weill Cornell Medicine, New York, NY

    Background/Purpose: Little is known about the patient perspective related to DMARD choice in RA. Our objective was to assess how patients decide whether to add…
  • Abstract Number: 1370 • 2019 ACR/ARP Annual Meeting

    Not All Joints Are Equal: Challenge DAS28 System and Identify Factors Leading to a Mismatch Between T2T and HAQ Among RA Patients Through Data Mining from Smart System of Disease Management (SSDM)

    Jing Yang1, Zhenbiao Wu 2, Yongfu Wang 3, Hua Wei 4, Yu Zhang 1, Xiaoling Liu 5, Xiaofeng Rong 6, Jinmei Zou 1, Xiaofei Shi 7, Hongbin Li 8, Rui Wu 9, Xiaoli Deng 10, Huiqiong Zhou 11, Yuan Jia 12, Wei Zhao 13, Shi Chen 12, Xuewu Zhang 12, Yingnan Li 14, Yingkun Nie 14, Yifang Mei 15, Jianyu Zhang 16, Hanyou Mo 17, li Sun 18, Yanfei Chen 19, Haili Shen 20, Dongsheng Li 21, Yonggang Zhao 22, Hui Xiao 23, Bing Wu 24, Yuhua Jia 22 and Fei Xiao 25, 1Central Hospital of MianYang, Mianyang, Sichuan, China (People's Republic), 2The First Affiliated Hospital of The Fourth Military Medical University, Xian, Shanxi, China (People's Republic), 3The First Affiliated Hospital of BaoTou Medical College, Baotou, Nei Mongol, China (People's Republic), 4Northern Jiangsu People's Hospital, Yangzhou, China (People's Republic), 5The 1st Affiliated Hospital of Guangzhou University of TCM, Guangzhou, China (People's Republic), 6The 1st Affiliated hospital of Chongqing medical University, Chongqing, Chongqing, China (People's Republic), 7First Affiliated Hospital of Henan University of Science and Technology, luoyang, Henan, China (People's Republic), 8The Affiliated Hospital of Inner Mongolia Medical University, Huhhot, Nei Mongol, China (People's Republic), 9The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China (People's Republic), 10Peking University Third Hospital, Beijing, Beijing, China (People's Republic), 11Fourth Medical Center of PLA Genal Hospital, Beijing, Beijing, China (People's Republic), 12Peking University People's Hospital, Beijing, Beijing, China (People's Republic), 13Chinese PLA General Hospital, Beijing, Beijing, China (People's Republic), 14The 2nd Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China (People's Republic), 15The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China (People's Republic), 16The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China (People's Republic), 17Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China (People's Republic), 18The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China (People's Republic), 19The First Hospital of Lanzhou University, Lanzhou, Gansu, China (People's Republic), 20The Second Hospital of Lanzhou University, Lanzhou, Gansu, China (People's Republic), 21Ganzhou People's Hospital, Ganzhou, Jiangxi, China (People's Republic), 22Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), 23Shanghai Gothic Internet Technology Co., Ltd, shanghai, Shanghai, China (People's Republic), 24Shanghai Gothic Internet Technology Co., Ltd, Shanghai, China (People's Republic), 25Shanghai Gothic Internet Technology Co., Ltd., shanghai, China (People's Republic)

    Background/Purpose: Treat to target (T2T), achieving a DAS28 score lower than 3.2, is the strategy recommended by ACR and EULAR. Health assessment questionnaire (HAQ) is…
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