ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstracts tagged "rheumatoid arthritis (RA) and tofacitinib"

  • Abstract Number: 580 • 2018 ACR/ARHP Annual Meeting

    Clinical Effectiveness of Tofacitinib 11mg Once Daily (QD) Versus Tofacitinib 5mg Twice Daily (BID) in the Corrona US RA Registry

    Stanley Cohen1, Heather J Litman2, Connie Chen3, Tatjana Lukic3, Ann Madsen3, Liza Takiya4, Kimberly J Dandreo2, Taylor Blachley2 and Jeffrey Greenberg2, 1Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX, 2Corrona LLC, Waltham, MA, 3Pfizer Inc, New York, NY, 4Pfizer Inc, Collegeville, PA

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA, originally approved at 5 mg twice daily (BID). In 2016, an extended-release…
  • Abstract Number: 581 • 2018 ACR/ARHP Annual Meeting

    Comparative Analysis of Outcomes Among Patients with Rheumatoid Arthritis Initiating Tofacitinib in Combination with Oral MTX Who Discontinue, Interrupt, or Persist with MTX

    Stanley Cohen1, Boulos Haraoui2, Jeffrey R. Curtis3, Timothy Smith4, John Woolcott5, David Gruben6, Christopher W Murray5, Noriko Iikuni4, Andrew Koenig5 and James Harnett4, 1Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX, 2Institut de Rhumatologie de Montreal, Montreal, QC, Canada, 3University of Alabama at Birmingham, Birmingham, AL, 4Pfizer Inc, New York, NY, 5Pfizer Inc, Collegeville, PA, 6Pfizer Inc, Groton, CT

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA, in combination with MTX or other non‑biologic (nb)DMARDs, or as monotherapy. Two…
  • Abstract Number: 606 • 2018 ACR/ARHP Annual Meeting

    Similiar Efficacy of Tofacinitib on Disease Activity in Rheumatoid Arthritis Patients with and without Previous Biologicals; Results from the Turkbio Regıstry

    Berrin Zengin1, Nevsun Inanc2, Servet Akar3, Gerçek Can1, Ediz Dalkiliç4, Abdurrahman Tufan5, Soner Senel6, Suleyman Serdar Koca7, Handan Yarkan1, Yavuz Pehlivan8, Zeynep Erturk9, Berna Goker5, Haner Direskeneli2, Merih Birlik1, Nurullah Akkoc10 and Fatos Onen1, 1Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey, 2Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 3Faculty of Medicine, Department of Rheumatology, Izmir Katip Celebi University, Izmir, Turkey, 4Rheumatology, Uludag University Faculty of Medicine, Bursa, Turkey, 5Internal Medicine-Rheumatology, Gazi University Faculty of Medicine, Ankara, Turkey, 6Rheumatology, Kayseri Erciyes University, Faculty of Medicine, Kayseri, Turkey, 7Rheumatology, Firat University Faculty of Medicine, Elazığ, Turkey, 8Rheumatology, Uludag University, Faculty of Medicine, Bursa, Turkey, 9Rheumatology, Marmara University Faculty of Medicine, istanbul, Turkey, 10Rheumatology, İzmir, Turkey, İzmir, Turkey

    Background/Purpose: Tofacitinib, a JAK3 inhibitor has been used to treat patients with rheumatoid arthritis (RA) in Turkey since 2015. The aim of this study was…
  • Abstract Number: 607 • 2018 ACR/ARHP Annual Meeting

    Clinical and Functional Response to Tofacitinib and Adalimumab in Patients with Rheumatoid Arthritis: Probability Plot Analysis of Results from the ORAL Strategy Trial

    Tsutomu Takeuchi1, Josef S. Smolen2, Roy Fleischmann3, Noriko Iikuni4, Haiyun Fan5, Koshika Soma6, Ermeg Akylbekova7 and Tomohiro Hirose8, 1Keio University, Tokyo, Japan, 2Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria, 3Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX, 4Pfizer Inc, New York, NY, 5Pfizer Inc, Collegeville, PA, 6Pfizer Inc, Groton, CT, 7IQVIA, Durham, NC, 8Pfizer Japan Inc, Tokyo, Japan

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA. ORAL Strategy (NCT02187055), a 12-month, global, Phase 3b/4 study, demonstrated that in…
  • Abstract Number: 533 • 2017 ACR/ARHP Annual Meeting

    Assessment of Radiographic Progression in Patients with Rheumatoid Arthritis Treated with Tofacitinib: Data from an Open-Label Long-Term Extension Study over 3 Years

    Désirée van der Heijde1, Jürgen Wollenhaupt2, Stanley B Cohen3, Sander Strengholt4, Ketti Terry5, Ryan DeMasi6, Kenneth Kwok7, Irina Lazariciu8 and Lisy Wang5, 1Leiden University Medical Center, Leiden, Netherlands, 2Schön-Klinik Hamburg-Eilbek Teaching Hospital of the University of Hamburg, Hamburg, Germany, 3Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX, 4Pfizer Inc, Capelle aan den IJssel, Netherlands, 5Pfizer Inc, Groton, CT, 6Pfizer Inc, Collegeville, PA, 7Pfizer Inc, New York, NY, 8QuintilesIMS, Saint-Laurent, QC, Canada

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA. The long-term safety and clinical efficacy of tofacitinib 5 and 10 mg…
  • Abstract Number: 535 • 2017 ACR/ARHP Annual Meeting

    Effect of a Step-up or Step-Down in Tofacitinib Dose on Efficacy and Safety in Long-Term Extension Studies

    Ruediger Mueller1, Hendrik Schulze-Koops2, Daniel E Furst3, Stanley B Cohen4, Kenneth Kwok5, Anna Maniccia5, Lisy Wang6, Ermeg Akylbekova7 and Johannes von Kempis1, 1Kantonsspital St. Gallen, St. Gallen, Switzerland, 2Klinikum der Universität München, Munich, Germany, 3UCLA, Los Angeles, CA, 4Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX, 5Pfizer Inc, New York, NY, 6Pfizer Inc, Groton, CT, 7QuintilesIMS, Durham, NC

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA. Efficacy and safety of tofacitinib 5 and 10 mg BID have been…
  • Abstract Number: 614 • 2017 ACR/ARHP Annual Meeting

    Effect of Tofacitinib on Reducing Pain in Patients with Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

    Alexis Ogdie1, Kurt de Vlam2, Iain B. McInnes3, Philip J Mease4, Philip Baer5, Tatjana Lukic6, Kenneth Kwok6, Cunshan Wang7, Ming-Ann Hsu7 and Anna Maniccia6, 1Division of Rheumatology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2UZ Leuven, Leuven, Belgium, 3Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom, 4Swedish Medical Center and University of Washington, Seattle, WA, 5Baer Weinberg MPC, Scarborough, ON, Canada, 6Pfizer Inc, New York, NY, 7Pfizer Inc, Groton, CT

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA), which has also been evaluated in other inflammatory rheumatic diseases…
  • Abstract Number: 1397 • 2017 ACR/ARHP Annual Meeting

    American College of Rheumatology Response Rates Determined Using 28 Versus 68/66 Joint Count in Patients with Rheumatoid Arthritis Receiving Tofacitinib in Phase 3 Studies

    Josef S. Smolen1, William Shergy2, Grace C. Wright3, Ryan DeMasi4, Kenneth Kwok5, Christopher F Mojcik5, Noriko Iikuni5, Svitlana Tatulych6 and Gustavo Citera7, 1Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 2Rheumatology Associates of North Alabama, Huntsville, AL, 3NYU Langone Medical Center, New York, NY, 4Pfizer Inc, Collegeville, PA, 5Pfizer Inc, New York, NY, 6Pfizer Inc, Groton, CT, 7Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). In a clinical trial setting, standard criteria for measuring the…
  • Abstract Number: 1421 • 2017 ACR/ARHP Annual Meeting

    Tofacitinib Monotherapy Improves Arterial Stiffness in Conventional Dmards Active Rheumatoid Arthritis Patients. a Cohort Study

    Kensuke Kume1, Kanzo Amano2, Susumu Yamada1, Toshikatsu Kanazawa3 and Kazuhiko Hatta4, 1Rheumatology, Hiroshima Clinic, Hiroshima, Japan, 2rheumatology., hiroshima clinic, Hiroshima, Japan, 3rheumatology, hiroshima clinic, hiroshima, Japan, 4Rheumatology, Hatta Clinic, Kure, Japan

    Background/Purpose: Patients with rheumatoid arthritis (RA) have an increased cardiovascular (CV) risk. We should have strategies for primary cardiovascular prevention in RA. We reported Tofacitinib(Tofa) plus…
  • Abstract Number: 1427 • 2017 ACR/ARHP Annual Meeting

    Monitoring of Absolute Lymphocyte Count in Patients with Rheumatoid Arthritis Treated with Tofacitinib

    Gerd R. Burmester1, Zoltan Szekanecz2, Pinaki Biswas3, Sriram Krishnaswami4, Christopher F Mojcik3, Hernan Valdez3, Jamie Geier3 and Sander Strengholt5, 1Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Free University and Humboldt University Berlin, Berlin, Germany, 2University of Debrecen Faculty of Medicine, Debrecen, Hungary, 3Pfizer Inc, New York, NY, 4Pfizer Inc, Groton, CT, 5Pfizer Inc, Capelle aan den IJssel, Netherlands

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA. Lymphopenia is a frequent feature of RA,1 and RA medications may also…
  • Abstract Number: 1437 • 2017 ACR/ARHP Annual Meeting

    C-Reactive Protein Levels in Patients with or without Structural Progression: A Post-Hoc Analysis from a Phase 3 Tofacitinib Trial

    Roy Fleischmann1, Carol A Connell2, Haiyun Fan3 and Sander Strengholt4, 1Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX, 2Pfizer Inc, Groton, CT, 3Pfizer Inc, Collegeville, PA, 4Pfizer Inc, Capelle aan den IJssel, Netherlands

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). We examined high sensitivity C-reactive protein (hsCRP) levels in relation…
  • Abstract Number: 2371 • 2017 ACR/ARHP Annual Meeting

    The Efficacy of Tofacitinib in Patients with Rheumatoid Arthritis Stratified By Baseline Body Mass Index

    Ara Dikranian1, Miguel Angel Gonzalez-Gay2, Frank Wellborne3, Jose Maria Alvaro-Gracia4, Liza Takiya5, Lori Stockert5, Douglass Chapman6, Svitlana Tatulych7, Palle Dahl8 and Jeffrey R. Curtis9, 1Cabrillo Center for Rheumatic Disease, San Diego, CA, 2Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 3Houston Institute for Clinical Research, Houston, TX, 4Hospital Universitario de La Princesa, IIS Princesa, Madrid, Spain, 5Pfizer Inc, Collegeville, PA, 6Pfizer Inc, New York, NY, 7Pfizer Inc, Groton, CT, 8Pfizer Inc, Ballerup, Denmark, 9University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). This post-hoc analysis aims to explore the efficacy of tofacitinib…
  • Abstract Number: 2493 • 2017 ACR/ARHP Annual Meeting

    Efficacy and Safety of Tofacitinib in Patients with Rheumatoid Arthritis and Inadequate Response or Intolerance to Prior Therapies

    John Tesser1, Ahmet Gül2, Ewa Olech3, Kurt Oelke4, Tatjana Lukic5, Christopher W Murray6, Chuanbo Zang6 and Liza Takiya6, 1Arizona Arthritis & Rheumatology Associates, Glendale, AZ, 2Istanbul University, Istanbul, Turkey, 3UNLV School of Medicine, Las Vegas, NV, 4Rheumatic Disease Center, Glendale, WI, 5Pfizer Inc, New York, NY, 6Pfizer Inc, Collegeville, PA

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Patients (pts) with RA generally receive conventional synthetic DMARDS (csDMARDs)…
  • Abstract Number: 2785 • 2017 ACR/ARHP Annual Meeting

    Serious Infections Associated with Tofacitinib in Rheumatoid Arthritis Patients Previously Treated with Methotrexate

    Marina Amaral de Avila Machado1, Cristiano S. Moura2, Steve Ferreira Guerra1, Jeffrey R. Curtis3, Michal Abrahamowicz4, Hassan Behlouli1 and Sasha Bernatsky5, 1Department of Medicine, McGill University Health Centre, Montreal, QC, Canada, 21Division of Clinical Epidemiology, McGill University Health Centre, Montreal, QC, Canada, 3Rheumatology & Immunology, University of Alabama at Birmingham, Birmingham, AL, 4Department of Medicine, McGill University Health Centre, Montreak, QC, Canada, 5Divisions of Rheumatology and Clinical Epidemiology, McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose: Little is known about the real-world safety of tofacitinib, an oral Janus kinase inhibitor. We compared serious infections associated with tofacitinib, disease-modifying antirheumatic drugs…
  • Abstract Number: 436 • 2017 ACR/ARHP Annual Meeting

    Baseline Anemia As a Predictor of Radiographic Progression in Tofacitinib-Treated Rheumatoid Arthritis Patients: Post Hoc Analyses from Two Phase 3 Trials

    Burkhard Moeller1, Axel Finckh2, Godehard Scholz1, Harry Shi3, Carol A Connell4 and Sander Strengholt5, 1Department for Rheumatology, Immunology and Allergology, University Hospital of Bern, Bern, Switzerland, 2University Hospital of Geneva, Geneva, Switzerland, 3Pfizer Inc, Collegeville, PA, 4Pfizer Inc, Groton, CT, 5Pfizer Inc, Capelle aan den IJssel, Netherlands

    Background/Purpose: Anemia in patients with rheumatoid arthritis (RA) can help to identify those with more rapid erosive disease.1,2 Tofacitinib is an oral Janus kinase inhibitor…
  • « Previous Page
  • 1
  • 2
  • 3
  • 4
  • Next Page »
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology