Abstract Number: 2450 • 2016 ACR/ARHP Annual Meeting
Do Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis Have Reduced Fertility and Parity? a Systematic Review
Background/Purpose: Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis (RA) often affect women of reproductive age. It remains unclear as to whether these inflammatory rheumatic conditions…Abstract Number: 1212 • 2016 ACR/ARHP Annual Meeting
A Combined Large Scale Meta-Analysis Identifies COG6 As a Novel Shared Risk Locus for Rheumatoid Arthritis and Systemic Lupus Erythematosus
Background/Purpose: One of the main limitations of the association studies in autoimmunity is the difficulty in identifying genetic risk variants with modest effects, given the…Abstract Number: 1579 • 2016 ACR/ARHP Annual Meeting
Small Rnaseq Reveals Different Plasma miRNA Signature in Patients with RA and SLE: A Pilot Study
Background/Purpose: MicroRNAs (miRNAs) are ~22-nt RNAs that post-transcriptionally regulate gene expression and serve as biomarkers of many disease states. Most previous plasma miRNA studies in…Abstract Number: 1758 • 2016 ACR/ARHP Annual Meeting
Physical Activity and Sedentary Behaviour in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis
Background/Purpose: Patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are at increased risk for premature cardiovascular disease. As sedentary behaviour and lack of…Abstract Number: 1791 • 2016 ACR/ARHP Annual Meeting
Loss of Elbow Hyperextension in Females with Early Rheumatologic Disease Was Common in Systemic Lupus Erythematosus and Rheumatoid Arthritis but Rare in Fibromyalgia
Background/Purpose: The elbow extension angle (ELB) is commonly given as 180o although most healthy females exhibit hyperextension(1). The loss of hyperextension (LOH) in a…Abstract Number: 2112 • 2016 ACR/ARHP Annual Meeting
Disease-Activity Associated Autoantibodies to Malondialdehyde-Modified Proteins Can be Isolated from Synovial B Cells in RA
Background/Purpose: Malondialdehyde (MDA) is a naturally occurring reactive aldehyde that arises during apoptosis or as a consequence of elevated reactive oxygen species and lipid peroxidation.…Abstract Number: 2236 • 2016 ACR/ARHP Annual Meeting
Effects of Repository Corticotropin Injection on Medication Use in Patients with Rheumatologic Conditions: A Claims Data Study
Background/Purpose: Repository corticotropin injection (RCI) may produce anti-inflammatory and immune-modulatory effects. This study examined the demographics of those who used RCI and the trends in…Abstract Number: 37 • 2015 ACR/ARHP Annual Meeting
Cardiovascular Disease in Immune-Mediated Inflammatory Diseases: Cross Sectional Analysis of the Influence of Demographic and Traditional Cardiovascular Risk Factors
Background/Purpose : Our aim was 1) to analyze the association between demographic and traditional cardiovascular risk factors (CVRF) and cardiovascular disease (CVD) in subjects affected…Abstract Number: 621 • 2015 ACR/ARHP Annual Meeting
Previous Diagnosis of Sjögren’s Syndrome As Rheumatoid Arthritis or Systemic Lupus Erythematosus
Background/Purpose: The diagnosis of Sjögren′s Syndrome (SS) is often difficult and many patients are symptomatic for years with other diagnoses before confirmation of SS. Overlapping…Abstract Number: 1251 • 2015 ACR/ARHP Annual Meeting
Physiological Evidence for Diversification of the IFNα- or IFNβ-Mediated Response Programs in Different Autoimmune Diseases
Background/Purpose: Presence of a type I interferon (IFN) signature is described for several autoimmune diseases, including systemic lupus erythematosus (SLE), multiple sclerosis (MS), myositis (IIM)…Abstract Number: 1819 • 2015 ACR/ARHP Annual Meeting
Comparison of Electrocardiographic ST-T Changes and QTc Duration in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis
Background/Purpose: Cardiovascular disease (CVD) is a leading cause of death in systemic lupus erythematosus (SLE) and in rheumatoid arthritis (RA). Longer corrected QT segments (QTc)…Abstract Number: 2679 • 2014 ACR/ARHP Annual Meeting
Mucosal-Associated Invariant T Cell Deficiency in Systemic Lupus Erythematosus
Background/Purpose Mucosal-associated invariant T (MAIT) cells contribute to protection against certain microorganism infections and play an important role in mucosal immunity. However, the role of…Abstract Number: 1401 • 2014 ACR/ARHP Annual Meeting
Higher-Order Neuropsychological Deficits Are Frequent and Occur Early in RA and SLE: The Impact of Basic Processing Abilities on Psychological Well-Being
Background/Purpose Deficits in higher-order cognitive abilities (episodic memory, executive functions) have been reported in patients with chronic inflammatory disorders, albeit inconsistently. We investigated whether such…Abstract Number: 1072 • 2014 ACR/ARHP Annual Meeting
Sex Ratio of Offspring Born to Women with Lupus and Rheumatoid Arthritis
Background/Purpose: Women with SLE are at increased risk for pregnancy complications and specific autoantibodies may result in preferential loss of female offspring. Studies on the…Abstract Number: 387 • 2014 ACR/ARHP Annual Meeting
Levels of IgG Autoantibodies to Oxidation-Associated MDA Neo-Determinants Are a Biomarker for Systemic Inflammation and Disease Activity in SLE and RA
Background/Purpose Monitoring disease activity in patients with autoimmune rheumatic disease is an essential part of clinical care. Highly reactive malondialdehyde (MDA) arise from reactive oxygen…