rheumatoid arthritis (RA) and sex bias Archives

Abstract Number: 1496 • ACR/ARHP Annual Meeting 2018
Sex Differences in the Achievement of Clinical Remission and Low MRI Synovitis Scores in Rheumatoid Arthritis
Joshua Baker¹, Mikkel Østergaard², Carson Maynard³, Michael D. George⁴, Daniel Baker⁵ and Philip G. Conaghan⁶, ¹Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, ²Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ³Rheumatology, University of Pennsylvania, Philadlphia, PA, ⁴Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, ⁵Johnson & Johnson, Spring House, PA, ⁶University of Leeds, Leeds, UK, Leeds, United Kingdom
Background/Purpose: Several prior studies have demonstrated poor clinical responses and reduced likelihood of achievement of remission among women with rheumatoid arthritis (RA). We aimed to…
Abstract Number: 165 • ACR/ARHP Annual Meeting 2017
Rheumatoid Arthritis Risk Polymorphisms in CCR6, SNP and Estrogen-Dependent Response to Immune Mediator Gene Expression, and NF-κb Transcriptional Activity: Crosstalk between the Immune and Endocrine Systems
Ming-Fen Ho¹, Tim Bongartz², James N. Ingle³, Liewei Wang¹ and Richard M. Weinshilboum¹, ¹Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, ²Emergency Medicine, Vanderbilt University, Nashville, TN, ³Department of Medical Oncology, Mayo Clinic, Rochester, MN
Background/Purpose: The rheumatoid arthritis (RA) risk locus CCR6 rs3093024 SNP is associated with increased risk of RA in a sex-specific pattern in Asian populations. Specifically,…
Abstract Number: 2388 • ACR/ARHP Annual Meeting 2017
Women and Men with Rheumatoid Arthritis Present with Different Risks for Glucocorticoid-Related Comorbidities
Dörte Huscher¹, Katinka Albrecht¹, Frank Buttgereit², Thorsten Eidner³, Stefan Kleinert⁴, Wolfgang Ochs⁵ and Angela Zink⁶, ¹Epidemiology Unit, German Rheumatism Research Centre (DRFZ), Berlin, Germany, ²Department of Rheumatology and Clinical Immunology, Charité Univeris, Berlin, Germany, ³Rheumatology/ Osteology, Friedrich-Schiller-University Jena, University Clinic, Jena, Germany, ⁴Rheumatologie, Praxisgemeinschaft Rheumatologie-Nephrologie, Rheumatologische Schwerpunktpraxis, Erlangen, Germany, ⁵Internistisch-rheumatologische Praxisgemeinschaft Bayreuth, Bayreuth, Germany, ⁶Epidemiology Unit / Rheumatology and Clinical Immunology, German Rheumatism Research Centre (DRFZ) / Charité University Hospital, Berlin, Germany
Background/Purpose: Osteoporosis, diabetes, hypertension and cardiovascular diseases are the most threatening glucocorticoid (GC)-related comorbidities in rheumatoid arthritis (RA), both from the patients and rheumatologists perspective1.…
Abstract Number: 466 • ACR/ARHP Annual Meeting 2016
Sexually Dimorphic Dysbiosis of Gut Microbiota in Tumor Necrosis Factor Transgenic Mice with Inflammatory-Erosive Arthritis
Richard Bell^1,2, Ronald Wood³, Christopher T. Ritchlin⁴, Edward Schwarz⁵ and Homaira Rahimi⁶, ¹Center for Musculoskelatal Research, University of Rochester, Rochester, NY, ²Pathology, University of Rochester, Rochester, NY, ³University of Rochester, Rochester, NY, ⁴Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁵Orthopedeatrics, University of Rochester, Rochester, NY, ⁶Rheumatology, University of Rochester/Golisano Children's Hosp, Rochester, NY
Background/Purpose: Recent studies identify gut microbiota dysbiosis as a possible contributor to rheumatoid arthritis (RA) pathogenesis. RA patients have significantly different microbiomes than healthy controls.…
Abstract Number: 514 • ACR/ARHP Annual Meeting 2016
Gender Difference Is Apparent in the Risk of Forefoot Deformity in Patients with Rheumatoid Arthritis
Kentaro Inui¹, Tatsuya Koike², Tadashi Okano¹, Kenji Mamoto³, Kazuki Orita¹, Yuko Sugioka⁴, Masahiro Tada⁵, Hiroaki Nakamura³ and Orita incl, ¹Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Center for Senile Degenerative Disorders, Osaka City University Medical School, Osaka, Japan, ³Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ⁴Center for Senile Degenerative Disorders (CSDD), Osaka City University Medical School, Osaka, Japan, ⁵Orthopedic Surgery, Osaka City General Hospital, Osaka, Japan
Background/Purpose: Forefoot involvement in patients with rheumatoid arthritis (RA) is common, and reported to be present in 50–90% of patients without any clear gender predisposition.…
Abstract Number: 1457 • ACR/ARHP Annual Meeting 2016
Early Onset Morbidity and Mortality in Female Tumor Necrosis Factor Transgenic Mice with Inflammatory-Erosive Arthritis and Interstitial Lung Disease
Richard Bell¹, Emily Wu², Ronald Wood³, Joe Chakkalakal², Javier Rangel-Moreno⁴, Maria de la Luz Garcia-Hernandez², Christopher T. Ritchlin⁵, Edward Schwarz⁶ and Homaira Rahimi⁷, ¹Center for Musculoskelatal Research, University of Rochester, Rochester, NY, ²University of Rochaester, Rochester, NY, ³University of Rochester, Rochester, NY, ⁴Allergy, Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁵Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁶Orthopedeatrics, University of Rochester, Rochester, NY, ⁷Rheumatology, University of Rochester/Golisano Children's Hosp, Rochester, NY
Background/Purpose: Although exacerbated morbidity and mortality in rheumatoid arthritis (RA) is frequently seen in women, the etiology of this sexual dimorphism remains unclear. Previously, we…
Abstract Number: 2812 • ACR/ARHP Annual Meeting 2014
Is Rheumatoid Arthritis the Same Disease in Women and Men?- Joint Damage in Patients with EARLY Rheumatoid Arthritis at 10 YEARS after Diagnosis
Juha Asikainen¹, Kalevi Kaarela², Heidi Mäkinen³, Hannu Kautiainen⁴, Pekka Hannonen⁵, Tuomas Rannio⁶ and Tuulikki Sokka⁷, ¹Jyvaskyla Central Hospital, Jyväskylä, Finland, ²Jyväskylä Central Hospital, Jyväskylä, Finland, ³Tampere University Hospital, Tampere, Finland, ⁴Medcare Oy, Äänekoski, Finland, ⁵Jyväskylä Central Hospital, Jyvaskyla, Finland, ⁶Kuopio University Hospital, Kuopio, Finland, ⁷Jyvaskyla Central Hospital, Jyvaskyla, Finland
Background/Purpose: Rheumatoid arthritis (RA) is suggested to be a more severe disease in women than in men as disease activity appears higher in women, and…

Abstracts tagged "rheumatoid arthritis (RA) and sex bias"

Sex Differences in the Achievement of Clinical Remission and Low MRI Synovitis Scores in Rheumatoid Arthritis

Rheumatoid Arthritis Risk Polymorphisms in CCR6, SNP and Estrogen-Dependent Response to Immune Mediator Gene Expression, and NF-κb Transcriptional Activity: Crosstalk between the Immune and Endocrine Systems

Women and Men with Rheumatoid Arthritis Present with Different Risks for Glucocorticoid-Related Comorbidities

Sexually Dimorphic Dysbiosis of Gut Microbiota in Tumor Necrosis Factor Transgenic Mice with Inflammatory-Erosive Arthritis

Gender Difference Is Apparent in the Risk of Forefoot Deformity in Patients with Rheumatoid Arthritis

Early Onset Morbidity and Mortality in Female Tumor Necrosis Factor Transgenic Mice with Inflammatory-Erosive Arthritis and Interstitial Lung Disease

Is Rheumatoid Arthritis the Same Disease in Women and Men?- Joint Damage in Patients with EARLY Rheumatoid Arthritis at 10 YEARS after Diagnosis