Abstracts tagged "rheumatoid arthritis (RA) and risk"

Abstract Number: 83 • 2018 ACR/ARHP Annual Meeting
The Risk of Developing Rheumatoid Arthritis Based on HLA-DQ Genotypes
Sami B. Kanaan¹, Oyku Sensoy² and J. Lee Nelson³, ¹Clinical Research Division, Fred Hutchinson Cancer Research Center, SEATTLE, WA, ²Clinical Research Division, Fred Hutchinson Cancer Research Center, seattle, WA, ³Fred Hutchinson Cancer Research Center, Seattle, WA
Background/Purpose: The strongest genetic risk for rheumatoid arthritis (RA) is contributed from the HLA region. RA-risk associated HLA-DRB1 alleles including *04:01/4/5/8, *01:01, *10:01, and *14:02…
Abstract Number: 1466 • 2018 ACR/ARHP Annual Meeting
Altered Count of NK Cells and Non-Classical Monocyte Subpopulation in the Pre-Clinical Phase of Rheumatoid Arthritis
Klára Prajzlerová¹, Olga Kryštůfková², Petra Hánová¹, Hana Hulejová³, Monika Gregová⁴, Karel Pavelka⁴, Jiri Vencovsky¹, Ladislav Šenolt⁵ and Mária Filková¹, ¹Department of Rheumatology, First Faculty of Medicine, Charles University and Rheumatology Institute, Prague, Czech Republic, Prague, Czech Republic, ²Department of Rheumatology, First Faculty of Medicine, Charles University and Rheumatology Institute, Prague, Czech Republic, prague, Czech Republic, ³Rheumatology Institute, Prague, Czech Republic, Prague, Czech Republic, ⁴Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, ⁵First Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic
Background/Purpose: Anti-citrullinated protein antibodies (ACPA) are detectable long before the manifestation of rheumatoid arthritis (RA). EULAR provided a clinical definition of individuals with arthralgia suspicious…
Abstract Number: 1909 • 2018 ACR/ARHP Annual Meeting
Impact and Timing of Smoking Cessation on Reducing Risk for Seropositive Rheumatoid Arthritis Among Women
Xinyi Liu¹, Cianna Leatherwood¹, Sara K. Tedeschi¹, Medha Barbhaiya², Cameron Speyer¹, Bing Lu³, Karen Costenbader¹, Elizabeth Karlson¹ and Jeffrey A. Sparks¹, ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Rheumatology, Hospital for Special Surgery, New York, NY, ³Division of Rheumatology, Immunology and Allergy, Brigham & Women's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Compared to never smoking, past and current smoking are both associated with increased risk of seropositive rheumatoid arthritis (RA). Thus, smoking cessation may delay…
Abstract Number: 2140 • 2018 ACR/ARHP Annual Meeting
Association of Hydroxychloroquine Use and Incident Atrial Fibrillation in Rheumatoid Arthritis: A Retrospective Study
Alisha Gupta¹, Aditya Joshi¹, Omar Saleem¹, Mary Chester-Wasko² and Tarun S. Sharma³, ¹Internal Medicine, Allegheny General Hospital, Pittsburgh, PA, ²Allegheny Health Network, Pittsburgh, PA, ³Rheumatology, Lupus Center of Excellence, Allegheny Health Network, Pittsburgh, PA
Background/Purpose: Hydroxychloroquine (HCQ) is a derivative of quinidine, a class 1a anti-arrhythmic agent used to prevent ventricular arrhythmias and recurrent atrial fibrillation (AFib). AFib occurs…
Abstract Number: 146 • 2017 ACR/ARHP Annual Meeting
Major Cardiovascular Events Among an Inception Cohort of Seniors with Rheumatoid Arthritis
Jessica Widdifield^1,2, Michael Paterson², Anjie Huang², Bindee Kuriya³, Carter Thorne⁴, Janet E. Pope⁵ and Sasha Bernatsky⁶, ¹Clinical Epidemiology, Research Institute of the McGill University Health Centre, Montreal, ON, Canada, ²Institute for Clinical Evaluative Sciences, Toronto, ON, Canada, ³Sinai Health System, University of Toronto, Toronto, ON, Canada, ⁴Southlake Regional Health Centre, Newmarket, ON, Canada, ⁵Department of Medicine, Division of Rheumatology, University of Western Ontario, St Joseph's Health Care, London, ON, Canada, ⁶Division of Clinical Epidemiology, Research Institute of the McGill University Health Centre, Montreal, QC, Canada
Background/Purpose: We previously observed that incident RA patients have an increased risk of cardiovascular (CV) mortality relative to the general population in Ontario. Our aim…
Abstract Number: 913 • 2017 ACR/ARHP Annual Meeting
High Erythrocyte Levels of the n-6 Polyunsaturated Fatty Acid Linoleic Acid Are Associated with Lower Risk of Subsequent Rheumatoid Arthritis in a Southern European Nested Case-Control Study
Paola de Pablo¹, Dora Romaguera^2,3, Helena Fisk⁴, Philip Calder⁴, Anne-Marie Quirke⁵, Alison Cartwright⁵, Salvatore Panico⁶, Amalia Mattiello⁶, Diana Gavrila⁷, Carmen Navarro⁷, Carlotta Sacerdote⁸, Paolo Vineis^2,9, Rosario Tumino¹⁰, William Ollier¹¹, Dominique Michaud^2,12, Elio Riboli², Patrick Venables⁵ and Benjamin Fisher¹³, ¹University of Birmingham, Birmingham, United Kingdom, ²Imperial College London, London, United Kingdom, ³CIBER-OBN (Fisiopatología de la Obesidad y Nutrición), University Hospital Son Espases, Palma, Spain, ⁴University of Southampton, Southampton, United Kingdom, ⁵Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom, ⁶Federico II University of Naples, Naples, Italy, ⁷Murcia Regional Health Council, Murcia, Spain, ⁸Città della Salute e della Scienza University-Hospital, Turin, Italy, ⁹Human Genetics Foundation, Turin, Italy, ¹⁰"Civic - M.P.Arezzo" Hospital, Ragusa, Italy, ¹¹Division of Population Health, Health Services Research and Primary Care, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom, ¹²Tufts University Medical School, Boston, MA, ¹³Rheumatology Research Group, University of Birmingham, Birmingham, United Kingdom
Background/Purpose: Long-chain n-3 (also known as omega-3) polyunsaturated fatty acids (PUFA), especially eicosapentaenoic acid (EPA; 20:5n-3) and docosahexaenoic acid (DHA; 22:6n-3), have long-been considered to…
Abstract Number: 983 • 2016 ACR/ARHP Annual Meeting
Objectively Assessed Sedentary Behaviour and Light Physical Activity Are Associated with Long-Term Cardiovascular Risk in People Living with Rheumatoid Arthritis Independently of Moderate-to-Vigorous Physical Activity
Sally Fenton^1,2, Jet Veldhuijzen van Zanten^2,3, George D. Kitas^2,4, Joan Duda⁴, Peter Rouse⁵, Chen-an Yu¹ and George Metsios^2,6, ¹School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom, ²Department of Rheumatology, Russells Hall Hospital, Dudley Group of Hospitals NHS Foundation Trust, Dudley, United Kingdom, ³University of Birmingham, Birmingham, United Kingdom, ⁴School of Sport, Exercise and Rehabilitation, University of Birmingham, Birmingham, United Kingdom, ⁵Department for Health, University of Bath, Bath, United Kingdom, ⁶Department of Physical Activity Exercise and Health, University of Wolverhampton, Walsall, United Kingdom
Background/Purpose: Rheumatoid Arthritis (RA) can result in functional disability and is associated with an increased risk of cardiovascular disease (CVD). In healthy adults and…
Abstract Number: 1039 • 2016 ACR/ARHP Annual Meeting
Estimation of the Risk of Developing Rheumatoid Arthritis in High-Risk Subjects : Systematic Review and Meta-Analysis
François Vercruysse¹, Vincent Germain¹, Thomas Barnetche², Marie-Elise Truchetet³ and Thierry Schaeverbeke², ¹Rheumatology, CHU Pellegrin, Bordeaux, France, BORDEAUX, France, ²Rheumatology, CHU Pellegrin, Bordeaux, France, Bordeaux, France, ³CHU Pellegrin, Bordeaux, France, Bordeaux, France
Background/Purpose: Identifying individuals at risk for rheumatoid arthritis (RA) development is a prerequisite to understand preclinical events and to develop prevention. Based on a systematic…
Abstract Number: 1480 • 2016 ACR/ARHP Annual Meeting
Determination of the Lipid Profile in Active Disease Leads to Incorrect Cardiovascular Risk Prediction in Early Rheumatoid Arthritis Patients
Samina A. Turk¹, Dirkjan van Schaardenburg^1,2, Willem F. Lems^1,3 and Mike T. Nurmohamed^1,3, ¹Rheumatology, Amsterdam Rheumatology and immunology Center, location Reade, Amsterdam, Netherlands, Amsterdam, Netherlands, ²Rheumatology, Amsterdam Rheumatology and immunology Center, location Academic Medical Center, Amsterdam, Netherlands, Amsterdam, Netherlands, ³Rheumatology, Amsterdam Rheumatology and immunology Center, VU University medical center, Amsterdam, Netherlands
Background/Purpose: Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity and mortality. This cardiovascular risk is mainly determined by the lipid profile, which may change…
Abstract Number: 2463 • 2016 ACR/ARHP Annual Meeting
Association Between High Sodium Intake and Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis
Gulsen Ozen¹, Ali Ugur Unal², Simge Saydam³, Murat Sunbul⁴, Kursat Tigen⁴, Haner Direskeneli⁵ and Nevsun Inanc¹, ¹Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ²Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, ³Marmara University Faculty of Medicine, Istanbul, Turkey, ⁴Department of Cardiology, Marmara University Faculty of Medicine, Istanbul, Turkey, ⁵Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey
Background/Purpose: High sodium intake has been reported to be associated with increased ACPA positivity in smoker RA patients. However, apart from this, the associations with…
Abstract Number: 28 • 2016 ACR/ARHP Annual Meeting
Baseline Serum Inflammatory Biomarkers at Cohort Entry in 1974 Predicted Cardiovascular Disease (CVD) Mortality from 1995 through 2015 in a Prospective, Community-Based Study of Incident Rheumatoid Arthritis (RA) Patients and Matched Non-RA (CN) Subjects
Alfonse T. Masi¹, Azeem A. Rehman², Laura Jorgenson³ and Jean C. Aldag³, ¹University of Illinois, College of Medicine at Peoria, Peoria, IL, ²Neurosurgery, University of West Virginia Medical School, Morgantown, WV, ³Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL
Baseline Serum Inflammatory Biomarkers at Cohort Entry in 1974 Predicted Cardiovascular Disease (CVD) Mortality from 1995 through 2015 in a Prospective, Community-Based Study of Incident Rheumatoid…
Abstract Number: 31 • 2015 ACR/ARHP Annual Meeting
Risk of Chronic Obstructive Pulmonary Disease in Rheumatoid Arthritis: A Population Based Cohort Study
Katherine McGuire¹, J Antonio Avina-Zubieta², Eric C. Sayre¹, JM Esdaile³ and Diane Lacaille⁴, ¹Arthritis Research Canada, Richmond, BC, Canada, ²Arthritis Research Canada / University of British Columbia, Vancouver, BC, Canada, ³Rheumatology, Arthritis Research Canada, Richmond, BC, Canada, ⁴Arthritis Research Centre, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: A link between chronic obstructive pulmonary disease (COPD) and inflammation has been established in a number of studies. This raises the question of whether…
Abstract Number: 482 • 2015 ACR/ARHP Annual Meeting
Erosions in the Foot at Baseline Are Predictive of Orthopedic Shoe Use after 10 Years of Treat to Target Therapy
Sytske Anne Bergstra¹, Rosaline van den Berg², Naghmeh Riyazi³, Gerda M. Steup-Beekman⁴, Peter A.H.M. van der Lubbe⁵, Pit J.S.M. Kerstens⁶, Willem F. Lems⁷, T. W. J. Huizinga⁸, Robert B.M. Landewé^9,10 and Cornelia F. Allaart¹, ¹Department of Rheumatology, Leiden Universitary Medical Center, Leiden, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands, ³Rheumatology, Haga Hospital, The Hague, Netherlands, ⁴Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Vlietland Hospital, Schiedam, Netherlands, ⁶Department of Rheumatology, Reade, Amsterdam, Netherlands, ⁷Department of Rheumatology, VU Universitary Medical Center, Amsterdam, Netherlands, ⁸Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁹Amsterdam Rheumatology & Immunology Center, Academic Medical Center, Amsterdam, Netherlands, ¹⁰Atrium Medical Center, Heerlen, Netherlands
Background/Purpose: Orthopaedic shoes (OS) may help to reduce pain and increase activity participation in rheumatoid arthritis (RA) patients, but should ideally not be needed. We…
Abstract Number: 909 • 2015 ACR/ARHP Annual Meeting
Smoking Behavior Changes after Rheumatoid Arthritis Diagnosis and Risk of Mortality during 36 Years of Prospective Follow-up
Jeffrey A. Sparks¹, Uyen Sa D.T. Nguyen^2,3, Shun-Chiao Chang^4,5, Yuqing Zhang⁶, Hyon Choi⁷ and Elizabeth W. Karlson⁴, ¹Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Clinical Epidemiology Research &Training Unit, Boston University School of Medicine, Boston, MA, ³Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ⁴Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁵Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁶Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁷Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Smoking is a major preventable cause of death and cessation is recommended for the general population. However, it is unclear whether being diagnosis with…
Abstract Number: 1213 • 2015 ACR/ARHP Annual Meeting
Prospective Study of Dietary Patterns and Risk of Rheumatoid Arthritis in Women
Bing Lu¹, Yang Hu², Jeffrey A. Sparks³, Karen H. Costenbader⁴, Frank Hu⁵ and Elizabeth W. Karlson¹, ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Nutrition, Harvard School of Public Health, Boston, MA, ³Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁴Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁵Harvard School of Public Health, Boston, MA
Background/Purpose: Although some individual dietary factors have been identified to be associated with the development of rheumatoid arthritis (RA), few studies have examined the effects…

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