ACR Meeting Abstracts

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Abstracts tagged "Rheumatoid arthritis (RA)"

  • Abstract Number: L01 • ACR Convergence 2021

    Immunogenicity of mRNA COVID-19 Vaccines at 4 and 12 Weeks Post Full Vaccination in Patients with Inflammatory Rheumatic Diseases

    Catherine Raptis1, Diego Andrey2, Christoph Berger3, Axel Finckh2, Pierre Lescuyer2, Adrian Ciurea4, Tanja Maletic1, Christos Polysopoulos1, Myriam Riek1, Almut Scherer1, Kim Lauper2, Burkhard Moeller5, Judith Safford6, Sandra Schweizer7, Isabell von Loga1, Nicolas Vuilleumier8 and Andrea Rubbert-Roth9, 1SCQM Foundation, Zurich, Switzerland, 2Geneva University Hospital, Geneva, Switzerland, 3University Hospital Basel, Basel, Switzerland, 4University Hospital Zurich, Zrich, Switzerland, 5Inselspital - University Hospital Bern, Bern, Switzerland, 6RheumaCura Foundation, Zurich, Switzerland, 7Swiss League Against Rheumatism, Zurich, Switzerland, 8University Hospital of Geneva, Geneva, Switzerland, 9Kantonspital St Gallen, St.Gallen, Switzerland

    Background/Purpose: Emerging evidence indicates that immunosuppressive therapies may result in reduced immunogenicity –and presumably reduced efficacy-  following vaccination with mRNA COVID-19 vaccines but long-term data…
  • Abstract Number: L02 • ACR Convergence 2021

    COVID-19 Vaccine in Immunosuppressed Adults with Autoimmune Diseases

    Ines Colmegna1, Mariana Useche1, Emmanouil Rampakakis2, Nathalie Amiable3, Emmanuelle Rollet-Labelle3, Louis Bessette4, Jo-Anne Costa4, Marc Dionne4, Mary-Ann Fitzcharles2, Elizabeth Hazel2, Deirdre McCormack2, Laetitia Michou4, Pantelis Panopalis2, Marc-Andre Langlois5, Sasha Bernatsky6 and Paul R. Fortin7, 1The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 2McGill University Health Centre, Montreal, QC, Canada, 3Centre de Recherche du CHU de Quebec, Quebec, Canada, 4Universite Laval, Quebec, QC, Canada, 5University of Ottawa, Ottawa, ON, Canada, 6McGill University, Montreal, QC, Canada, 7CHU de Quebec - Universite Laval, Quebec, Canada

    Background/Purpose: Immunocompromised conditions and/or a history of autoimmune disease were exclusion criteria of the initial SARS-CoV-2 vaccines clinical trials. We assessed the safety and immunogenicity…
  • Abstract Number: L10 • ACR Convergence 2021

    A Randomized, Double-Blinded, Placebo-Controlled, Phase 2 Study of Safety, Tolerability and Efficacy of Pirfenidone in Patients with Rheumatoid Arthritis Interstitial Lung Disease

    joshua solomon1, Felix Woodhead2, Sonye Danoff3, Shana Haynes-Harp4, Tanvi Naik5, Cathie Spino5, Shelley Hurwitz6, Rie Maurer6, Daniel Chambers7, Martin Kolb8, Hiliary Goldberg6 and Ivan Rosas4, 1National Jewish Health, Denver, CO, 2University of Leicester, Leicester, United Kingdom, 3Johns Hopkins University, Baltimore, MD, 4Baylor College of Medicine, Houston, TX, 5University of Michigan, Ann Arbor, MI, 6Brigham and Womens Hospital, Boston, MA, 7University of Queensland, Brisbane, Australia, 8McMaster University, Hamilton, ON, Canada

    Background/Purpose: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a prevalent and morbid condition leading to premature death in 10% of those affected. The TRAIL1 trial…
  • Abstract Number: L11 • ACR Convergence 2021

    Cardiovascular Risk of Hydroxychloroquine in the Treatment of Rheumatoid Arthritis: A Retrospective Cohort Study

    ELVIRA D'ANDREA1, Rishi Desai2, Mengdong He3, Robert Glynn4, Hemin Lee2, Michael Weinblatt2, Daniel Solomon5 and Seoyoung Kim2, 1Brigham & Women's Hospital and Harvard Medical School, Boston, MA, 2Brigham and Women's Hospital, Boston, MA, 3UCLA David Geffen School of Medicine, Los Angeles, CA, 4Brigham & Women's Hospital, Boston, MA, 5Brigham and Women's Hospital, Newton, MA

    Background/Purpose: Hydroxychloroquine (HCQ) is a commonly used 1st-line disease-modifying antirheumatic drug (DMARD) for patients with rheumatoid arthritis (RA) in the U.S., while methotrexate (MTX) is…
  • Abstract Number: 166 • 2020 Pediatric Rheumatology Symposium

    Resident Memory T Cells in Human RA Synovium Display Restricted TCR Clones

    Margaret Chang1, Anais Levescot 2, Nathan Nelson-Maney 3, Rachel Blaustein 4, Kellen Winden 1, Allyn Morris 4, Spoorthi Balu 4, Alexandra Wactor 4, Kevin Wei 5, Lauren Henderson 6, Rachael Clark 4, Deepak Rao 4, Robert Fuhlbrigge 7 and Peter Nigrovic 8, 1Boston Children's Hospital, Boston, 2Boston, 3, 4Brigham and Women's Hospital, Boston, 5BWH, Boston, 6Boston Children's Hospital, Watertown, Massachusetts, 7University of Colorado, Aurora, 8Boston Children's Hospital, Boston, Massachusetts

    Background/Purpose: Resident memory T cells (TRM) are site-specific memory T cells that take up long-term residence in peripheral tissues and aid in pathogen defense. Dysregulated…
  • Abstract Number: L02 • 2019 ACR/ARP Annual Meeting

    Multiple Industrial Air Pollutants and Anti-Citrullinated Protein Antibody Positivity

    Naizhuo Zhao 1, Audrey Smargiassi 2, Marianne Hatzopoulou 3, Ines Colmegna 4, Marie Hudson 5, Marvin Fritzler 6, Philip Awadalla 7 and Sasha Bernatsky8, 1Research Institute of the McGill University Health Centre, Montreal, Canada, 2University of Montreal, Montreal, Canada, 3University of Toronto, Toronto, Canada, 4McGill University Health Center, Montreal, QC, Canada, 5Jewish General Hospital, Lady Davis Institute for Medical Research, and Department of Medicine, McGill University, Montreal, Canada, 6Cumming School of Medicine, University of Calgary, Calgary, Canada, 7Ontario Institute for Cancer Research, Toronto, Canada, 8Research Institute of the McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose: Studies of associations between industrial air emissions and rheumatic disease, or diseases-related serological biomarkers, are few. Moreover, previous evaluations typically studied individual (not mixed)…
  • Abstract Number: L12 • 2019 ACR/ARP Annual Meeting

    Safety and Efficacy of Olokizumab in a Phase III Trial of Patients with Moderately to Severely Active Rheumatoid Arthritis Inadequately Controlled by Methotrexate – CREDO1 Study

    Evgeniy Nasonov 1, Saeed Fatenejad 2, Elena Korneva 3, Diana Krechikova 4, Alexey Maslyansky 5, Tatyana Plaksina 6, Marina Stanislav 7, Rumen Stoilov 8, Tamara Tyabut 9, Sergey Yakushin 10, Elena Zonova 11 and Mark Genovese12, 1FSBSI "Scientific Research Institute of Rheumatology n.a. V.A. Nasonova", Moscow, Russia, 2SFC Medica, Charlotte, North Carolina, 3R-Pharm, Moscow, Russia, 4Non-governmental Healthcare Institution "Regional Clinical Hospital at Smolensk station of OJSC "Russian Railways, Smolensk, Russia, 5SBHI "North-West Federal Medical Research Center n.a. V.A.Almazov" of the Ministry of Healthcare of the Russian Federation, St-Petersburg, Russia, 6SBHI of Nizhny Novgorod Region "Nizhny Novgorod Regional Clinical Hospital n.a. P.A.Semashko", N.Novgorod, Russia, 7V.A. Nasonova Research Rheumatology Institute, Moscow, Russia, 8UMHAT St. Ivan Rilski, Clinic of Rheumatology, Sofia, Bulgaria, 9Belarusian Medical Academy of Postgraduate Education, City Clinical Hospital N1, Minsk, Belarus, 10Ryazan State Medical University, Ryazan, Russia, 11Novosibirsk State Medical University, State Clinical Polyclinic 1, Novosibirsk, Russia, 12Stanford University, Stanford, CA

    Background/Purpose: Olokizumab (OKZ) is a new humanized monoclonal antibody targeting IL-6 1, 2. Here we present the results of the first phase III study of…
  • Abstract Number: 2822 • 2019 ACR/ARP Annual Meeting

    Depression and Subsequent Risk for Incident Seronegative Rheumatoid Arthritis Among Women

    Jeffrey Sparks1, Susan Malspeis 1, Jill Hahn 2, Andrea Roberts 2, Laura Kubzansky 2 and Karen Costenbader 1, 1Brigham and Women's Hospital, Boston, MA, 2Harvard School of Public Health, Boston, MA

    Background/Purpose: Depression is associated with elevated systemic inflammation and risk of several chronic diseases including lupus, psoriasis, and inflammatory bowel disease. However, the association between…
  • Abstract Number: 40 • 2019 ACR/ARP Annual Meeting

    Inflammation and Neuronal Growth Factors in Rheumatoid Arthritis

    Caroline Wasén1, Lovisa Leifsdottir 2, Roda Abdalla 1, Lina Juzokaite 1, Karin Andersson 1, Malin Erlandsson 1, Marie Kalm 3 and Maria Bokarewa 1, 1Department of Rheumatology and Inflammation Research, the Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, Gothenburg, Sweden, 2Department of Rheumatology and Inflammation Research, the Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, Gotheburg, Sweden, 3hDepartment of Pharmacology, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden, Gothenburg, Sweden

    Background/Purpose: Depression and cognitive impairment are frequently reported in rheumatoid arthritis (RA). We have recently presented that reduced hippocampus volume may be linked to functional…
  • Abstract Number: 124 • 2019 ACR/ARP Annual Meeting

    Treatment with Abatacept but Not with TNF Blockers, Is Associated with a Reduction of Constitutively Elevated Circulating Follicular Helper T Cells in Rheumatoid Arthritis

    Maria-Eugenia Miranda-Carus1, Paula Fortea-Gordo 2, Laura Nuño 3, Alejandro Villalba 4, Maria-Jose Santos-Bornez 2, Diana Peiteado 2, Irene Monjo 1 and Alejandro Balsa 5, 1FIBHULP-IdiPAZ-Hospital La Paz-Rheumatology, Madrid, Spain, 2FIBHULP-IdiPAZ-Hospital La Paz, Madrid, Spain, 3Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, Madrid, Spain, 4FIBHULP-IdiPAZ-Hospital La Paz-Rheumatology, Madrid, 5Immuno-Rheumatology Research Group, IdiPaz & Rheumatology Department. La Paz University Hospital, Madrid, Spain

    Background/Purpose: Circulating CD4 T cells that express CXCR5 together with PD-1 and/or ICOS are considered as counterparts of bona fide Tfh cells and function as…
  • Abstract Number: 208 • 2019 ACR/ARP Annual Meeting

    Self-Reported Sleep Disturbances in Rheumatoid Arthritis (RA)

    Patricia Katz1, Sofia Pedro 2 and Kaleb Michaud 3, 1University of California, San Francisco, san francisco, CA, 2FORWARD, The National Databank for Rheumatic Diseases, Wichita, KS, 3FORWARD, The National Databank for Rheumatic Diseases and University of Nebraska Medical Center, Wichita, KS

    Background/Purpose: Sleep disturbances (SD) are reported to be common in RA but relatively few studies have addressed the issue. We examined the frequency and severity…
  • Abstract Number: 414 • 2019 ACR/ARP Annual Meeting

    Treat-to-Target Approach in the Management of Elderly Rheumatoid Arthritis Patients

    Vivek Joseph 1, Swetha Vontela 2, Surjeet Dheer3, Molly Weinberg 4, Zuhayr Haq 2 and Arundathi Jayatilleke 5, 1Drexel University, PHILADELPHIA, PA, 2Drexel University, Philadelphia, 3Mercy Catholic Medical Center, Philadelphia, 4Drexel University, Philadlephia, 5Drexel, Philadelphia, PA

    Background/Purpose: With the advent of biologic therapy for RA, the American College of Rheumatology advocates a treat to target (TTT) approach in the treatment of…
  • Abstract Number: 457 • 2019 ACR/ARP Annual Meeting

    Serum Myostatin in Patients with Rheumatoid Arthritis and Its Correlations with Body Compositions and the Disease Activity

    Yoko Wada1, Masanori Sudo 2, Daisuke Kobayashi 2, Takeshi Kuroda 3 and Masaaki Nakano 4, 1Niigata Rinko Hospital, Niigata, Niigata, Japan, 2Division of Clinical Nephrology and Rheumatology, Niigata University, Niigata, Niigata, Japan, 3Health administration office, Niigata University, Niigata, Niigata, Japan, 4School of Health Sciences, Faculty of Medicine, Niigata University, Niigata, Niigata, Japan

    Background/Purpose: Altered body composition is a common feature of patients with rheumatoid arthritis (RA), up to two-thirds of affected patients showing loss of muscle mass…
  • Abstract Number: 496 • 2019 ACR/ARP Annual Meeting

    Assessment of Anti-Cyclic Citrullinated Protein and Connective Tissue Disease Screening Questionnaire in Healthy Adults from the Oklahoma Immune Cohort

    McKayla Muse1, Ly Tran 1, Carla J. Guthridge 2, Nancy Redinger 2 and Judith James 3, 1Oklahoma Medical Research Foundation, Oklahoma City, 2Oklahoma Medical Research Foundation, Oklahoma City, OK, 3Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, Oklahoma City, OK

    Background/Purpose: Anti-CCP antibodies are present in the serum of healthy individuals who are at risk of developing RA and serve as an important tool for…
  • Abstract Number: 540 • 2019 ACR/ARP Annual Meeting

    Comparing Real-world Retention Rates in a Matched Cohort of Rheumatoid Arthritis Patients Who Either Remained on the Etanercept Originator or Switched to a Biosimilar

    Lisa Baganz1, Anja Strangfeld 2, Peter Herzer 3, Andreas Krause 4, Hans-Peter Tony 5 and Angela Zink 6, 1German Rheumatism Research Center, Berlin, Germany, 2German Rheumatism Research Center (DRFZ), Berlin, Germany, 3Scientific Advisory Board, München, Germany, 4Immanuel Krankenhaus, Berlin, Germany, 5Department of Rheumatology/Clinical Immunology, University Hospital, Wuerzburg, Germany, Würzburg, Germany, 6German Rheumatism Research Centre and Charité University medicine, Berlin, Germany

    Background/Purpose: In Germany, the first etanercept biosimilar was licensed in 2016. In contrast to other European countries there is no uniform recommendation for the prescription…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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